Isolation and characterization of new proliferating cell nuclear antigen (POL30) mutator mutants that are defective in DNA mismatch repair

scientific article published on October 2002

Isolation and characterization of new proliferating cell nuclear antigen (POL30) mutator mutants that are defective in DNA mismatch repair is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.22.19.6669-6680.2002
P932PMC publication ID134031
P698PubMed publication ID12215524

P2093author name stringRichard D Kolodner
Hernan Flores-Rozas
Patrick J Lau
P2860cites workReconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteinsQ22010786
Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexesQ24290314
Post-replicative base excision repair in replication fociQ24534209
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication fociQ24602221
Crystal structure of the eukaryotic DNA polymerase processivity factor PCNAQ27730804
A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repairQ36553838
Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteinsQ36568343
Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase delta and DNA polymerase epsilonQ36573422
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL geneQ36643609
Mammalian DNA nucleotide excision repair reconstituted with purified protein components.Q36697936
Mechanisms and biological effects of mismatch repairQ37041860
Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA.Q38320783
Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repairQ39449001
Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genesQ40022200
Microbial Determinations by Flow CytometryQ41135036
The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiaeQ41430030
Novel dominant mutations in Saccharomyces cerevisiae MSH6.Q41711225
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeastQ42427955
Stimulation of eukaryotic flap endonuclease-1 activities by proliferating cell nuclear antigen (PCNA) is independent of its in vitro interaction via a consensus PCNA binding regionQ43690417
Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repairQ46348708
A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repairQ64389285
Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repairQ74064844
Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complexQ27929854
The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairsQ27930815
The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesisQ27931779
Enhancement of MSH2-MSH3-mediated mismatch recognition by the yeast MLH1-PMS1 complexQ27932428
Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeastQ27934236
Heteroduplex DNA correction in Saccharomyces cerevisiae is mismatch specific and requires functional PMS genesQ27934736
Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3.Q27934985
The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutationsQ27935158
exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repairQ27935389
Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repairQ27938608
Eukaryotic DNA mismatch repairQ27939116
Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correctionQ27939611
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesisQ27939891
A rapid method for localized mutagenesis of yeast genesQ28131692
Replication protein A stimulates proliferating cell nuclear antigen-dependent repair of abasic sites in DNA by human cell extractsQ28142871
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complexQ28142999
Proliferating cell nuclear antigen is required for DNA excision repairQ28182009
D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNAQ28183697
PCNA binding through a conserved motifQ28274063
Biochemistry and genetics of eukaryotic mismatch repairQ28282377
ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repairQ28610858
Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalphaQ28610863
Replacement of chromosome segments with altered DNA sequences constructed in vitroQ29614231
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repairQ29615027
Mismatch repair in replication fidelity, genetic recombination, and cancer biologyQ29616483
The distribution of the numbers of mutants in bacterial populationsQ29620123
Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolismQ32068528
Mammalian DNA mismatch repairQ33847720
Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2.Q33951095
In vivo analysis reveals that the interdomain region of the yeast proliferating cell nuclear antigen is important for DNA replication and DNA repairQ33968478
DNA mismatch repair and genetic instabilityQ34090778
A mutation of the yeast gene encoding PCNA destabilizes both microsatellite and minisatellite DNA sequencesQ34606404
Temperature-sensitive mutations in the yeast DNA polymerase I geneQ34618611
Two modes of FEN1 binding to PCNA regulated by DNA.Q35116227
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzymeQ35739744
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectDNA mismatch repairQ2984243
P304page(s)6669-6680
P577publication date2002-10-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleIsolation and characterization of new proliferating cell nuclear antigen (POL30) mutator mutants that are defective in DNA mismatch repair
P478volume22

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cites work (P2860)
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Q27659293Analysis of the role of PCNA-DNA contacts during clamp loading
Q33726437Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks
Q36761745Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms
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Q28709604DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae
Q35989544Dead-End Elimination with a Polarizable Force Field Repacks PCNA Structures
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Q27679146Distinct Structural Alterations in Proliferating Cell Nuclear Antigen Block DNA Mismatch Repair
Q28261787Exonuclease 1-dependent and independent mismatch repair
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Q33961620PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair.
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Q28551589The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis
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Q38940317Understanding how mismatch repair proteins participate in the repair/anti-recombination decision
Q36338245Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates.

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