scholarly article | Q13442814 |
P356 | DOI | 10.1007/S10689-011-9431-4 |
P698 | PubMed publication ID | 21404117 |
P50 | author | Peter Propping | Q1634165 |
Hans Konrad Schackert | Q40929188 | ||
Elke Holinski-Feder | Q43376219 | ||
Gabriela Möslein | Q43376252 | ||
Brigitte Royer-Pokora | Q43376295 | ||
Christoph Engel | Q56261483 | ||
Magnus von Knebel Doeberitz | Q87739754 | ||
Monika Morak | Q88115609 | ||
Verena Steinke-Lange | Q89459811 | ||
Nils Rahner | Q114515679 | ||
Timm Goecke | Q117235137 | ||
Beate Betz | Q117255561 | ||
Christian P Pox | Q117255562 | ||
P2093 | author name string | Johannes H Hegemann | |
Karin Hardt | |||
Kati Servan | |||
Haniyeh Yazdanparast | |||
Sven Boris Heick | |||
German HNPCC consortium | |||
Robin Küppers | |||
P2860 | cites work | The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2 | Q24596494 |
A novel genetic system to detect protein-protein interactions | Q27860915 | ||
The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer | Q28137782 | ||
DNA mismatch repair | Q28256190 | ||
The distribution of the numbers of mutants in bacterial populations | Q29620123 | ||
A yeast two-hybrid assay provides a simple way to evaluate the vast majority of hMLH1 germ-line mutations. | Q31146866 | ||
Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations. | Q33957827 | ||
DNA mismatch repair and genetic instability | Q34090778 | ||
The selection for mismatch repair defects in hereditary nonpolyposis colorectal cancer: revising the mutator hypothesis. | Q34405031 | ||
HNPCC mutation MLH1 P648S makes the functional protein unstable, and homozygosity predisposes to mild neurofibromatosis type 1. | Q34547820 | ||
Functional analysis of human MutSalpha and MutSbeta complexes in yeast | Q34693488 | ||
The UvrD helicase and its modulation by the mismatch repair protein MutL. | Q35100583 | ||
Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair | Q35537125 | ||
Mutations in DNA mismatch repair genes: implications for DNA damage signaling and drug sensitivity (review). | Q35686587 | ||
Genetic predisposition to colorectal cancer | Q35930688 | ||
Mechanisms in eukaryotic mismatch repair | Q36564560 | ||
Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants. | Q36568353 | ||
Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations | Q36570003 | ||
Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair | Q37592729 | ||
Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair | Q39695410 | ||
Stabilized, long-term expression of heterodimeric proteins from tricistronic mRNA. | Q40856640 | ||
The human PMS2L proteins do not interact with hMLH1, a major DNA mismatch repair protein | Q40963280 | ||
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast | Q42427955 | ||
Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity | Q42698843 | ||
Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system | Q43847787 | ||
Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR). | Q44498341 | ||
Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae | Q47713981 | ||
Functional Significance and Clinical Phenotype of Nontruncating Mismatch Repair Variants of MLH1 | Q59273262 | ||
Mediating mismatch repair | Q73311211 | ||
Sixteen rare sequence variants of the hMLH1 and hMSH2 genes found in a cohort of 254 suspected HNPCC (hereditary non-polyposis colorectal cancer) patients: mutations or polymorphisms? | Q77299844 | ||
Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer | Q77495184 | ||
The effect of genetic background on the function of Saccharomyces cerevisiae mlh1 alleles that correspond to HNPCC missense mutations | Q79518237 | ||
Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays | Q80352228 | ||
P433 | issue | 2 | |
P921 | main subject | Lynch syndrome | Q783644 |
P304 | page(s) | 273-284 | |
P577 | publication date | 2011-06-01 | |
P1433 | published in | Familial Cancer | Q15761917 |
P1476 | title | Missense variants in hMLH1 identified in patients from the German HNPCC consortium and functional studies | |
P478 | volume | 10 |
Q39389539 | Assessment of the InSiGHT Interpretation Criteria for the Clinical Classification of 24 MLH1 and MSH2 Gene Variants. |
Q34163755 | C-terminal fluorescent labeling impairs functionality of DNA mismatch repair proteins |
Q45718448 | Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors. |
Q88009101 | Evaluation of MLH1 variants of unclear significance |
Q92093286 | Full-length transcript amplification and sequencing as universal method to test mRNA integrity and biallelic expression in mismatch repair genes |
Q38932044 | Functional testing strategy for coding genetic variants of unclear significance in MLH1 in Lynch syndrome diagnosis |
Q47177393 | Haplotype analysis suggest that the MLH1 c.2059C > T mutation is a Swedish founder mutation. |
Q38029584 | Pathological assessment of mismatch repair gene variants in Lynch syndrome: past, present, and future |
Q30413890 | Q48P mutation in the hMLH1 gene associated with Lynch syndrome in three Hungarian families |
Q34533276 | The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome |
Search more.