| scholarly article | Q13442814 |
| P50 | author | Alison E. Gammie | Q54488552 |
| Mark D. Rose | Q55837835 | ||
| P2093 | author name string | Naz Erdeniz | |
| Afshan Nanji | |||
| Barbara Devlin | |||
| Julia Beaver | |||
| P2860 | cites work | Initiation of methyl-directed mismatch repair | Q64389906 |
| Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer | Q71689243 | ||
| Four novel MSH2 / MLH1 gene mutations in portuguese HNPCC families | Q73305796 | ||
| Modulation of MutS ATP hydrolysis by DNA cofactors | Q73543806 | ||
| MSH2 codon 322 Gly to Asp seems not to confer an increased risk for colorectal cancer susceptibility | Q74450981 | ||
| Mutations of hMLH1 and hMSH2 in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with microsatellite instability and abnormalities of mismatch repair protein expression | Q77706024 | ||
| The Escherichia coli MutL protein physically interacts with MutH and stimulates the MutH-associated endonuclease activity | Q77765360 | ||
| Identification of germline MSH2 gene mutations in endometrial cancer not fulfilling the new clinical criteria for hereditary nonpolyposis colorectal cancer | Q79073717 | ||
| High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12. | Q40388905 | ||
| The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase | Q40570055 | ||
| Instability of simple sequence DNA in Saccharomyces cerevisiae | Q40655124 | ||
| Hypermutability and mismatch repair deficiency in RER+ tumor cells | Q41508298 | ||
| MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast | Q42427955 | ||
| Clues to the pathogenesis of familial colorectal cancer | Q42622043 | ||
| The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair | Q44530427 | ||
| Mispair specificity of methyl-directed DNA mismatch correction in vitro | Q44909730 | ||
| Effect of proline and glycine residues on dynamics and barriers of loop formation in polypeptide chains | Q45310103 | ||
| The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer | Q46652176 | ||
| Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae | Q47713981 | ||
| Functional genetic tests of DNA mismatch repair protein activity in Saccharomyces cerevisiae | Q47962525 | ||
| Frequent somatic mutations of hMSH3 with reference to microsatellite instability in hereditary nonpolyposis colorectal cancers | Q48047180 | ||
| MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2. | Q48065235 | ||
| Lynch syndrome: genetics, natural history, genetic counseling, and prevention. | Q48371688 | ||
| Distinct molecular surfaces and hydrophobicity of amino acid residues in proteins. | Q52053482 | ||
| 'Marker swap' plasmids: convenient tools for budding yeast molecular genetics. | Q52526054 | ||
| hMLH1 and hMSH2 mutations in families with familial clustering of gastric cancer and hereditary non-polyposis colorectal cancer. | Q53388325 | ||
| Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer. | Q53452567 | ||
| Mutator phenotypes of common polymorphisms and missense mutations in MSH2. | Q54360036 | ||
| Isolation and characterization of the Escherichia coli mutH gene product. | Q54397103 | ||
| In vitro and in vivo studies of MutS, MutL and MutH mutants: correlation of mismatch repair and DNA recombination. | Q54529584 | ||
| Protein modelling for all | Q57075376 | ||
| Structural invariants in protein folding | Q59064399 | ||
| Hereditary non-polyposis colorectal cancer (HNPCC): phenotype-genotype correlation between patients with and without identified mutation | Q61757262 | ||
| DNA template requirements for human mismatch repair in vitro | Q64387816 | ||
| A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair | Q64389285 | ||
| Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis | Q22122362 | ||
| Functional analysis of human MLH1 and MSH2 missense variants and hybrid human-yeast MLH1 proteins in Saccharomyces cerevisiae | Q24291685 | ||
| Human exonuclease I is required for 5' and 3' mismatch repair | Q24292224 | ||
| A defined human system that supports bidirectional mismatch-provoked excision | Q24298110 | ||
| hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6 | Q24323176 | ||
| Genetic and physical maps of Saccharomyces cerevisiae | Q24599455 | ||
| MSH2 missense mutations alter cisplatin cytotoxicity and promote cisplatin-induced genome instability | Q24810372 | ||
| Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA | Q27627633 | ||
| The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch | Q27627644 | ||
| Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair | Q27629464 | ||
| Rapid and efficient site-specific mutagenesis without phenotypic selection | Q27860608 | ||
| A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae | Q27860636 | ||
| Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair | Q27932017 | ||
| Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions | Q27932283 | ||
| Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3. | Q27934985 | ||
| Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair | Q27938608 | ||
| Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis | Q27939891 | ||
| Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast | Q28131604 | ||
| DNA mismatch repair | Q28256190 | ||
| The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer | Q28256988 | ||
| Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer | Q28257360 | ||
| Genetic mapping of a locus predisposing to human colorectal cancer | Q28268634 | ||
| Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs | Q28287503 | ||
| The nature of the accessible and buried surfaces in proteins | Q28296598 | ||
| Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice | Q28593189 | ||
| hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA | Q28610839 | ||
| Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma | Q29615026 | ||
| Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair | Q29615027 | ||
| Cancer statistics, 2005 | Q29617572 | ||
| Protein degradation and protection against misfolded or damaged proteins | Q29618400 | ||
| Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair | Q29618879 | ||
| The distribution of the numbers of mutants in bacterial populations | Q29620123 | ||
| Microsatellite instability in cancer of the proximal colon | Q29620692 | ||
| Database resources of the National Center for Biotechnology Information. | Q30825513 | ||
| Reconstitution of 5'-directed human mismatch repair in a purified system | Q33222844 | ||
| Human mismatch repair: reconstitution of a nick-directed bidirectional reaction | Q33224078 | ||
| Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations. | Q33957827 | ||
| Isolation and characterization of point mutations in mismatch repair genes that destabilize microsatellites in yeast | Q34012877 | ||
| Import of proteins into mitochondria. The precursor of cytochrome c1 is processed in two steps, one of them heme-dependent | Q34055233 | ||
| eShadow: a tool for comparing closely related sequences | Q34343012 | ||
| Structure and function of mammalian DNA ligases | Q34463842 | ||
| Negative epistasis between natural variants of the Saccharomyces cerevisiae MLH1 and PMS1 genes results in a defect in mismatch repair | Q34480201 | ||
| DNA mismatch repair defects: role in colorectal carcinogenesis | Q34568596 | ||
| MLH1 mutations differentially affect meiotic functions in Saccharomyces cerevisiae | Q34617068 | ||
| Recombination-mediated PCR-directed plasmid construction in vivo in yeast | Q34624355 | ||
| DNA mismatch correction in a defined system | Q34674714 | ||
| Dominant negative mutator mutations in the mutS gene of Escherichia coli | Q34726651 | ||
| Role of DNA mismatch repair defects in the pathogenesis of human cancer | Q35085461 | ||
| Native state proline isomerization: an intrinsic molecular switch | Q35196998 | ||
| DNA mismatch repair: molecular mechanisms and biological function | Q35550610 | ||
| Mutations in DNA mismatch repair genes: implications for DNA damage signaling and drug sensitivity (review). | Q35686587 | ||
| Helical kink and channel behaviour: a comparative study with the peptaibols alamethicin, trichotoxin and antiamoebin | Q35688410 | ||
| Microsatellite instability and mutation of DNA mismatch repair genes in gliomas. | Q35753493 | ||
| Mismatch repair and DNA damage signalling | Q35848516 | ||
| Mismatch repair proteins: key regulators of genetic recombination | Q35910241 | ||
| EXO1-A multi-tasking eukaryotic nuclease. | Q35913244 | ||
| Genetic predisposition to colorectal cancer | Q35930688 | ||
| Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database | Q35940640 | ||
| Identifying DNA methylation biomarkers of cancer drug response | Q36217806 | ||
| In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair | Q36235057 | ||
| Saccharomyces cerevisiae pms2 mutations are alleles of MLH1, and pms2-2 corresponds to a hereditary nonpolyposis colorectal carcinoma-causing missense mutation | Q36560284 | ||
| Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations | Q36570003 | ||
| Evaluation of screening strategy for detecting hereditary nonpolyposis colorectal carcinoma | Q38290753 | ||
| Escherichia coli MutL loads DNA helicase II onto DNA. | Q38308417 | ||
| MutS and MutL activate DNA helicase II in a mismatch-dependent manner | Q38337755 | ||
| Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein | Q38346658 | ||
| Use of SSCP analysis to identify germline mutations in HNPCC families fulfilling the Amsterdam criteria | Q38475625 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Saccharomyces cerevisiae | Q719725 |
| P1104 | number of pages | 15 | |
| P304 | page(s) | 707-721 | |
| P577 | publication date | 2007-08-24 | |
| P1433 | published in | Genetics | Q3100575 |
| P1476 | title | Functional characterization of pathogenic human MSH2 missense mutations in Saccharomyces cerevisiae | |
| P478 | volume | 177 |
| Q63965569 | A Novel, Drug Resistance-Independent, Fluorescence-Based Approach To Measure Mutation Rates in Microbial Pathogens |
| Q47988257 | Blocking protein quality control to counter hereditary cancers |
| Q47605252 | CRIMEtoYHU: a new web tool to develop yeast-based functional assays for characterizing cancer-associated missense variants. |
| Q37110421 | Cell-cycle and DNA damage regulation of the DNA mismatch repair protein Msh2 occurs at the transcriptional and post-transcriptional level. |
| Q83394008 | Characterization of MSH2 variants by endogenous gene modification in mouse embryonic stem cells |
| Q55380392 | Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast. |
| Q92238742 | Comparative Genomics for the Elucidation of Multidrug Resistance in Candida lusitaniae |
| Q37385768 | Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases |
| Q83227500 | Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome |
| Q37396010 | Contemporary, yeast-based approaches to understanding human genetic variation |
| Q39581441 | Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays |
| Q91891556 | Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing |
| Q40823475 | Distinct requirements within the Msh3 nucleotide binding pocket for mismatch and double-strand break repair |
| Q28602193 | Efforts to make and apply humanized yeast |
| Q37360596 | Exposure to the lampricide 3-trifluoromethyl-4-nitrophenol results in increased expression of carbohydrate transporters in Saccharomyces cerevisiae |
| Q41352646 | Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization |
| Q33739955 | Functional analysis of human mismatch repair gene mutations identifies weak alleles and polymorphisms capable of polygenic interactions |
| Q50549930 | Functional characterization of rare missense mutations in MLH1 and MSH2 identified in Danish colorectal cancer patients. |
| Q93012448 | Functional interrogation of Lynch syndrome-associated MSH2 missense variants via CRISPR-Cas9 gene editing in human embryonic stem cells |
| Q33939068 | Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families |
| Q54466704 | Germline MLH1 and MSH2 mutations in Italian pancreatic cancer patients with suspected Lynch syndrome. |
| Q34301290 | HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα. |
| Q38019869 | History of protein-protein interactions: from egg-white to complex networks |
| Q35755784 | Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact |
| Q35053925 | Integrative analysis of hereditary nonpolyposis colorectal cancer: the contribution of allele-specific expression and other assays to diagnostic algorithms |
| Q87331668 | Lynch Syndrome in high risk Ashkenazi Jews in Israel |
| Q34164054 | Lynch syndrome-associated mutations in MSH2 alter DNA repair and checkpoint response functions in vivo |
| Q43919200 | Mechanisms of pathogenicity in human MSH2 missense mutants. |
| Q39348928 | Mismatch repair analysis of inherited MSH2 and/or MSH6 variation pairs found in cancer patients. |
| Q35034398 | Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches |
| Q38271431 | Multiple factors insulate Msh2-Msh6 mismatch repair activity from defects in Msh2 domain I. |
| Q35954461 | Mutability and mutational spectrum of chromosome transmission fidelity genes |
| Q37128670 | Mutation rates, spectra, and genome-wide distribution of spontaneous mutations in mismatch repair deficient yeast |
| Q36821500 | Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants |
| Q36182997 | Pancreatic cancer and a novel MSH2 germline alteration |
| Q38029584 | Pathological assessment of mismatch repair gene variants in Lynch syndrome: past, present, and future |
| Q36350781 | Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations |
| Q36512211 | Proteasome inhibition rescues clinically significant unstable variants of the mismatch repair protein Msh2. |
| Q37308166 | Reciprocal regulation of nuclear import of the yeast MutSalpha DNA mismatch repair proteins Msh2 and Msh6. |
| Q36276354 | Residues in the N-terminal domain of MutL required for mismatch repair in Bacillus subtilis |
| Q28551589 | The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis |
| Q92857979 | The Mutator Phenotype: Adapting Microbial Evolution to Cancer Biology |
| Q36447028 | The hMSH2(M688R) Lynch syndrome mutation may function as a dominant negative |
| Q36571784 | The rate and spectrum of microsatellite mutation in Caenorhabditis elegans and Daphnia pulex |
| Q50967175 | Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. |
| Q28383634 | Yeast toxicogenomics: genome-wide responses to chemical stresses with impact in environmental health, pharmacology, and biotechnology |
| Q97529348 | Yeast-based assays for the functional characterization of cancer-associated variants of human DNA repair genes |
| Q24630038 | Yeast: an experimental organism for 21st Century biology |
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