| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Giulia Rancati | |
| Federica Natali | |||
| P2860 | cites work | Cancer as an evolutionary and ecological process | Q22122026 |
| Strategies of tumor immune evasion | Q22305820 | ||
| A method to select for mutator DNA polymerase deltas in Saccharomyces cerevisiae | Q83339427 | ||
| The evolution of low mutation rates in experimental mutator populations of Saccharomyces cerevisiae | Q84444250 | ||
| Polymorphic mutation frequencies in clinical isolates of Staphylococcus aureus: the role of weak mutators in the development of fluoroquinolone resistance | Q85917111 | ||
| Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales | Q91111571 | ||
| Heterozygous mutations cause genetic instability in a yeast model of cancer evolution | Q91284090 | ||
| Genomic characterization of metastatic breast cancers | Q92227242 | ||
| Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens | Q93012784 | ||
| Clonal Heterogeneity Influences the Fate of New Adaptive Mutations. | Q47104008 | ||
| DNA mismatch repair and its many roles in eukaryotic cells | Q47777273 | ||
| Evolutionary implications of the frequent horizontal transfer of mismatch repair genes | Q50117948 | ||
| Up-regulation of mismatch repair genes MSH6, PMS2 and MLH1 parallels development of genetic instability and is linked to tumor aggressiveness and early PSA recurrence in prostate cancer. | Q51350568 | ||
| High-accuracy lagging-strand DNA replication mediated by DNA polymerase dissociation. | Q52334064 | ||
| Genomic Instability Promoted by Overexpression of Mismatch Repair Factors in Yeast: A Model for Understanding Cancer Progression. | Q52589171 | ||
| Absence of azole or echinocandin resistance in Candida glabrata isolates in India despite background prevalence of strains with defects in DNA mismatch repair pathway. | Q52611995 | ||
| Insertional inactivation of mutS in Staphylococcus aureus reveals potential for elevated mutation frequencies, although the prevalence of mutators in clinical isolates is low. | Q52861291 | ||
| Mutator phenotype confers advantage in Escherichia coli chronic urinary tract infection pathogenesis. | Q54485886 | ||
| Role of mutator alleles in adaptive evolution. | Q54564129 | ||
| Costs and Benefits of High Mutation Rates: Adaptive Evolution of Bacteria in the Mouse Gut | Q56944626 | ||
| Functional Interaction Between and DNA Repair in Yeast May Uncover a Role of , and Somatic Variants in Cancer Development | Q57072621 | ||
| Genetic Interactions in Cancer Progression and Treatment | Q63383811 | ||
| Hereditary colorectal cancer | Q73088287 | ||
| Ploidy controls the success of mutators and nature of mutations during budding yeast evolution | Q80141689 | ||
| Role of hypermutability on bacterial fitness and emergence of resistance in experimental osteomyelitis due to Staphylococcus aureus | Q80832162 | ||
| Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint. | Q24564215 | ||
| Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas | Q24617520 | ||
| Elucidating the molecular architecture of adaptation via evolve and resequence experiments | Q26783005 | ||
| Evolutionary determinants of cancer | Q26801710 | ||
| Replicative DNA polymerase mutations in cancer | Q26825747 | ||
| The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2 | Q26851138 | ||
| Global analysis of protein localization in budding yeast | Q27653962 | ||
| Functional profiling of the Saccharomyces cerevisiae genome | Q27860544 | ||
| Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis | Q27860815 | ||
| Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing | Q27860948 | ||
| A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2-MSH6 complex disrupts mismatch recognition | Q27934451 | ||
| Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae | Q27936822 | ||
| Eukaryotic DNA mismatch repair | Q27939116 | ||
| Two decades beyond BRCA1/2: Homologous recombination, hereditary cancer risk and a target for ovarian cancer therapy | Q28087741 | ||
| DNA polymerases at the eukaryotic fork-20 years later | Q28255094 | ||
| Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers | Q28256331 | ||
| The clonal evolution of tumor cell populations | Q28271546 | ||
| Deciphering signatures of mutational processes operative in human cancer | Q28283300 | ||
| Germline and somatic polymerase ε and δ mutations define a new class of hypermutated colorectal and endometrial cancers | Q28286394 | ||
| A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer | Q28289377 | ||
| DNA mismatch repair in eukaryotes and bacteria | Q28291067 | ||
| High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading | Q28510929 | ||
| Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load | Q28710085 | ||
| The Evolution of Mutation Rate in Finite Asexual Populations | Q29301497 | ||
| The life history of 21 breast cancers | Q29614642 | ||
| A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. | Q33351293 | ||
| Mutator mutations enhance tumorigenic efficiency across fitness landscapes | Q33466042 | ||
| Muller's ratchet decreases fitness of a DNA-based microbe | Q33588611 | ||
| A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability | Q33591410 | ||
| Differences between germline and somatic mutation rates in humans and mice | Q33701930 | ||
| Eukaryotic Mismatch Repair in Relation to DNA Replication | Q33711830 | ||
| Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans | Q33741252 | ||
| The effect of population bottlenecks on mutation rate evolution in asexual populations | Q33763823 | ||
| The optimal rate of chromosome loss for the inactivation of tumor suppressor genes in cancer | Q33782233 | ||
| Rate and effects of spontaneous mutations that affect fitness in mutator Escherichia coli | Q37716243 | ||
| Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer | Q37775178 | ||
| Control over DNA replication in time and space | Q38030237 | ||
| Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases. | Q38191981 | ||
| Antimicrobial susceptibility testing in biofilm-growing bacteria | Q38207154 | ||
| Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polymerase δ mutation in human cells | Q38709274 | ||
| Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future | Q38758819 | ||
| Tracking the Evolution of Non-Small-Cell Lung Cancer | Q38818761 | ||
| Cohesin mutations in human cancer | Q38840393 | ||
| DNA Polymerases Divide the Labor of Genome Replication. | Q38855041 | ||
| Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy | Q39421725 | ||
| The current value of determining the mismatch repair status of colorectal cancer: A rationale for routine testing | Q39426336 | ||
| Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal | Q39700353 | ||
| Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance | Q40738359 | ||
| Human Cancers Express a Mutator Phenotype: Hypothesis, Origin, and Consequences | Q40974722 | ||
| Systematic exploration of essential yeast gene function with temperature-sensitive mutants | Q41541576 | ||
| Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii | Q41671780 | ||
| Extreme chromosomal instability forecasts improved outcome in ER-negative breast cancer: a prospective validation cohort study from the TACT trial | Q41721139 | ||
| Enrichment and elimination of mutY mutators in Escherichia coli populations | Q42031695 | ||
| Competition between high- and higher-mutating strains of Escherichia coli | Q42736352 | ||
| Evolution of Mutation Rates in Rapidly Adapting Asexual Populations. | Q42741265 | ||
| Constitutional mismatch repair-deficiency syndrome | Q42793022 | ||
| Germline MSH2 and MLH1 mutational spectrum in HNPCC families from Poland and the Baltic States | Q43075069 | ||
| The G67E mutation in hMLH1 is associated with an unusual presentation of Lynch syndrome | Q43189001 | ||
| Aneuploidy acts both oncogenically and as a tumor suppressor | Q44738012 | ||
| Patterns of Genomic Variation in the Opportunistic Pathogen Candida glabrata Suggest the Existence of Mating and a Secondary Association with Humans | Q46237990 | ||
| Somatic microsatellite mutations as molecular tumor clocks | Q46820533 | ||
| The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome | Q33913152 | ||
| Mutation frequency and biological cost of antibiotic resistance in Helicobacter pylori | Q33952076 | ||
| Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations. | Q33957827 | ||
| Mucoidy, quorum sensing, mismatch repair and antibiotic resistance in Pseudomonas aeruginosa from cystic fibrosis chronic airways infections | Q34117477 | ||
| An elevated mutation frequency favors development of vancomycin resistance in Staphylococcus aureus | Q34142416 | ||
| Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics | Q34267466 | ||
| Genetic clonal diversity predicts progression to esophageal adenocarcinoma | Q34505745 | ||
| High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection. | Q34508854 | ||
| Tempo and mode of genome evolution in a 50,000-generation experiment | Q34535938 | ||
| The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness | Q34609052 | ||
| EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae | Q34609730 | ||
| Evaluating the impact of population bottlenecks in experimental evolution | Q34616074 | ||
| Fitness evolution and the rise of mutator alleles in experimental Escherichia coli populations. | Q34616140 | ||
| Paradoxical relationship between chromosomal instability and survival outcome in cancer | Q34988001 | ||
| Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene. | Q35063954 | ||
| Identification of new human origins of DNA replication by an origin-trapping assay. | Q35131778 | ||
| The role of mutators in the emergence of antibiotic-resistant bacteria | Q35177659 | ||
| Proliferation of mutators in A cell population | Q35618973 | ||
| Predictors of progression in Barrett's esophagus II: baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression | Q35658948 | ||
| Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta. | Q35728727 | ||
| A Genetic Incompatibility Accelerates Adaptation in Yeast | Q35729697 | ||
| Complete genetic linkage can subvert natural selection | Q35748721 | ||
| Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer | Q35901185 | ||
| MLH1 promoter hypermethylation in the analytical algorithm of Lynch syndrome: a cost-effectiveness study | Q36035692 | ||
| Functional characterization of pathogenic human MSH2 missense mutations in Saccharomyces cerevisiae. | Q36083305 | ||
| Identifying mutator phenotypes among fluoroquinolone-resistant strains of Streptococcus pneumoniae using fluctuation analysis. | Q36094891 | ||
| Mismatch repair | Q36283640 | ||
| Mouse models of DNA mismatch repair in cancer research | Q36583537 | ||
| Overexpression of MutSα Complex Proteins Predicts Poor Prognosis in Oral Squamous Cell Carcinoma | Q36988709 | ||
| MSH-2 and MLH-1 protein expression in Muir Torre syndrome-related and sporadic sebaceous neoplasms | Q37188356 | ||
| APC mutations in colorectal tumors with mismatch repair deficiency | Q37383704 | ||
| High fidelity and lesion bypass capability of human DNA polymerase delta | Q37414576 | ||
| Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells. | Q37419092 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P304 | page(s) | 713 | |
| P577 | publication date | 2019-08-06 | |
| P1433 | published in | Frontiers in Genetics | Q2499875 |
| P1476 | title | The Mutator Phenotype: Adapting Microbial Evolution to Cancer Biology | |
| P478 | volume | 10 |
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