scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Päivi Peltomäki | Q41787886 |
P2860 | cites work | Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis | Q22122362 |
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability | Q24319995 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | pathogenesis | Q372016 |
DNA mismatch repair | Q2984243 | ||
P304 | page(s) | 1174-1179 | |
P577 | publication date | 2003-03-01 | |
P1433 | published in | Journal of Clinical Oncology | Q400292 |
P1476 | title | Role of DNA mismatch repair defects in the pathogenesis of human cancer | |
P478 | volume | 21 |
Q34325954 | 10 rare tumors that warrant a genetics referral. |
Q33552273 | A conserved MutS homolog connector domain interface interacts with MutL homologs |
Q36161227 | A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations |
Q54703592 | A large MSH2 Alu insertion mutation causes HNPCC in a German kindred. |
Q36375623 | A novel germline MLH1 mutation causing Lynch Syndrome in patients from the Republic of Macedonia |
Q41549186 | A novel heterozygous germline deletion in MSH2 gene in a five generation Chinese family with Lynch syndrome |
Q36540457 | A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair |
Q28274709 | ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background |
Q35588408 | Aberrations in the mismatch repair genes and the clinical impact on oesophageal squamous carcinomas from a high incidence area in South Africa |
Q35690218 | Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System |
Q26781643 | Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling |
Q28298882 | Alterations of copy number of methylation pattern in mismatch repair genes by methylation specific-multiplex ligation-dependent probe amplification in cases of colon cancer |
Q37321792 | Altered expression of the mismatch repair genes in DF-1 cells infected with the avian leukosis virus subgroup A. |
Q39645543 | Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway |
Q34565224 | An intronic mutation in MLH1 associated with familial colon and breast cancer. |
Q33576170 | Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden |
Q93052870 | Analysis of Molecular Pretreated Tumor Profiles as Predictive Biomarkers of Therapeutic Response and Survival Outcomes after Neoadjuvant Therapy for Rectal Cancer in Moroccan Population |
Q54281830 | Analysis of genome instability in breast cancer. |
Q42793806 | Analysis of hMLH1 and hMSH2 gene dosage alterations in hereditary nonpolyposis colorectal cancer patients by novel methods |
Q33247666 | Analysis of the excision step in human DNA mismatch repair |
Q38328409 | Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system. |
Q40569371 | Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine. |
Q40275526 | Assessing the pathogenicity of MLH1 missense mutations in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with clinical, genetic and functional features. |
Q37308298 | Assessment of functional effects of unclassified genetic variants |
Q44177099 | Association between Mismatch-repair Genetic variation and the Risk of Multiple Primary Cancers: A Meta-Analysis |
Q35587031 | Association between monoallelic MUTYH mutation and colorectal cancer risk: a meta-regression analysis |
Q44077157 | Association of hOGG1 Ser326Cys polymorphism with colorectal cancer risk: an updated meta-analysis including 5235 cases and 8438 controls |
Q53268028 | Asymptomatic synchronous quintuple primary cancers. |
Q37424404 | BaxΔ2 Family Alternative Splicing Salvages Bax Microsatellite-Frameshift Mutations. |
Q34270970 | Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene |
Q35399306 | Biomarkers and molecular diagnosis of gastrointestinal and pancreatic neoplasms |
Q28072468 | Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and others |
Q53456801 | CD133 mRNA expression and microsatellite instability in colorectal carcinoma |
Q24798955 | Cadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2-MSH6 complex |
Q37031517 | Cancer pharmacogenomics: role of DNA repair genetic polymorphisms in individualizing cancer therapy. |
Q53292592 | Cancer risk assessment using genetic panel testing: considerations for clinical application. |
Q36996117 | Cancer stem cells with genetic instability: the best vehicle with the best engine for cancer |
Q79845333 | Childhood T-cell non-Hodgkin's lymphoma, colorectal carcinoma and brain tumor in association with café-au-lait spots caused by a novel homozygous PMS2 mutation |
Q37523898 | Clinical biomarkers in oncology: focus on colorectal cancer |
Q91672149 | Clinical significance of MLH1/MSH2 for stage II/III sporadic colorectal cancer |
Q59798138 | Clinical utility of tumor mutational burden in patients with non-small cell lung cancer treated with immunotherapy |
Q35954814 | Clinicopathological features and management of cancers in lynch syndrome |
Q55924124 | Colorectal cancer |
Q39334444 | Colorectal cancer molecular profiling: from IHC to NGS in search of optimal algorithm |
Q33798999 | Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions |
Q53361302 | Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations. |
Q33829127 | Constitutional mismatch repair deficiency and childhood leukemia/lymphoma--report on a novel biallelic MSH6 mutation |
Q43001852 | Constitutional mismatch repair deficiency syndrome: Do we know it? |
Q38576104 | Constitutional mismatch repair deficiency syndrome: clinical description in a French cohort. |
Q42793022 | Constitutional mismatch repair-deficiency syndrome |
Q34809944 | Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg? |
Q34542463 | Contribution of the BOP1 gene, located on 8q24, to colorectal tumorigenesis |
Q41705402 | Correlation between polymorphisms in DNA mismatch repair genes and the risk of primary hepatocellular carcinoma for the Han population in northern China |
Q35597163 | Cost effectiveness of a new strategy to identify HNPCC patients |
Q47105352 | Crosstalk between mismatch repair and base excision repair in human gastric cancer |
Q42148377 | Cytological findings of langerhans cell sarcoma in a case of quintuple cancer |
Q37020817 | DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers |
Q38713996 | DNA mismatch repair deficiency and hereditary syndromes in Latino patients with colorectal cancer |
Q89558876 | DNA mismatch repair in the context of chromatin |
Q35031411 | DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy. |
Q33529216 | DNA polymorphism and risk of esophageal squamous cell carcinoma in a population of North Xinjiang, China |
Q37083718 | DNA repair dysfunction in gastrointestinal tract cancers |
Q35885592 | Deciphering the mismatch recognition cycle in MutS and MSH2-MSH6 using normal-mode analysis |
Q33356760 | Decoding the histone code: Role of H3K36me3 in mismatch repair and implications for cancer susceptibility and therapy |
Q44319548 | Defects in the DNA mismatch repair system do not contribute to the development of childhood wilms tumors |
Q28249351 | Deficiency of MSH2 expression is associated with clear cell renal cell carcinoma |
Q33820887 | Deficiency of hMLH1 and hMSH2 expression is a poor prognostic factor in Early Gastric Cancer (EGC). |
Q38868401 | Deficient Mismatch Repair and the Role of Immunotherapy in Metastatic Colorectal Cancer |
Q37081098 | Deficient mismatch repair system in patients with sporadic advanced colorectal cancer |
Q40249105 | Demonstration and characterization of mutations induced by Helicobacter pylori organisms in gastric epithelial cells |
Q37432433 | Destabilization of the MutSα's protein-protein interface due to binding to the DNA adduct induced by anticancer agent carboplatin via molecular dynamics simulations |
Q36693677 | Development of a cost-effective high-throughput process of microsatellite analysis involving miniaturized multiplexed PCR amplification and automated allele identification |
Q38204965 | Diagnostic criteria for constitutional mismatch repair deficiency syndrome: suggestions of the European consortium 'care for CMMRD' (C4CMMRD). |
Q36059087 | Do hereditary syndrome-related gynecologic cancers have any specific features? |
Q28534756 | Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway |
Q35124554 | Drug metabolism and homologous recombination repair in radiosensitization with gemcitabine |
Q38316881 | Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair. |
Q38739461 | Dynamics of MutS-mismatched DNA complexes are predictive of their repair phenotypes |
Q37087324 | E. coli mismatch repair acts downstream of replication fork stalling to stabilize the expanded (GAA.TTC)(n) sequence |
Q27012841 | Early-onset colorectal cancer: a separate subset of colorectal cancer |
Q39362273 | Effects of hyperthermia on Hsp27 (HSPB1), Hsp72 (HSPA1A) and DNA repair proteins hMLH1 and hMSH2 in human colorectal cancer hMLH1-deficient and hMLH1-proficient cell lines. |
Q30396620 | Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population |
Q36436073 | Engineered disulfide-forming amino acid substitutions interfere with a conformational change in the mismatch recognition complex Msh2-Msh6 required for mismatch repair |
Q42108356 | Enhancing Therapeutic Efficacy of Cisplatin by Blocking DNA Damage Repair |
Q27644397 | Escherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivo |
Q90396604 | Essential Oil from Carpesium abrotanoides L. Induces Apoptosis via Activating Mitochondrial Pathway in Hepatocellular Carcinoma Cells |
Q33888955 | Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-β. |
Q35787908 | Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment |
Q38974172 | Exo1 independent DNA mismatch repair involves multiple compensatory nucleases |
Q28261787 | Exonuclease 1-dependent and independent mismatch repair |
Q89849938 | Expanding the Scope of Immunotherapy in Colorectal Cancer: Current Clinical Approaches and Future Directions |
Q38530342 | Exploring the Mechanisms of Gastrointestinal Cancer Development Using Deep Sequencing Analysis. |
Q41352646 | Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization |
Q33801710 | Fabrication of Nanoscale "Curtain Rods" for DNA Curtains Using Nanoimprint Lithography |
Q49911660 | Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae |
Q42833087 | Functional characterization of MLH1 missense variants identified in Lynch syndrome patients. |
Q36083305 | Functional characterization of pathogenic human MSH2 missense mutations in Saccharomyces cerevisiae. |
Q24619622 | Functional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separation |
Q42130318 | Gadd45 in stress signaling |
Q35847556 | Gene expression profiling in non-human primate jejunum, ileum and colon after total-body irradiation: a comparative study of segment-specific molecular and cellular responses |
Q53370638 | Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters. |
Q34008801 | Genetic predisposition to colorectal cancer: where we stand and future perspectives |
Q37468316 | Genetic risk and gynecologic cancers. |
Q33732282 | Genetic screening for familial gastric cancer |
Q37512381 | Genetic screening in young women diagnosed with endometrial cancer. |
Q31139897 | Genetic testing strategies in newly diagnosed endometrial cancer patients aimed at reducing morbidity or mortality from lynch syndrome in the index case or her relatives |
Q36822429 | Genetic-based biomarkers and next-generation sequencing: the future of personalized care in colorectal cancer |
Q38212634 | Genetics of endometrial cancer |
Q38940530 | Genomics of Esophageal Cancer and Biomarkers for Early Detection |
Q26774708 | Gut microbiota imbalance and colorectal cancer |
Q47738263 | Heat shock proteins and DNA repair mechanisms: an updated overview |
Q28085485 | Hereditary Syndromes Manifesting as Endometrial Carcinoma: How Can Pathological Features Aid Risk Assessment? |
Q37597246 | Hereditary cancer syndromes in Latino populations: genetic characterization and surveillance guidelines |
Q36060735 | Hereditary nonpolyposis colorectal cancer (Lynch syndrome): criteria for identification and management |
Q79098523 | Hereditary nonpolyposis colorectal cancer and related conditions |
Q47301537 | Hereditary nonpolyposis colorectal carcinoma (HNPCC) and HNPCC-like families: Problems in diagnosis, surveillance, and management |
Q34977063 | Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management |
Q64096442 | High expression of SMARCE1 predicts poor prognosis and promotes cell growth and metastasis in gastric cancer |
Q30356611 | Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2. |
Q47766916 | Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro |
Q57458098 | Identification of Lynch syndrome risk variants in the Romanian population |
Q64229250 | Identification of key genes and pathways involved in microsatellite instability in colorectal cancer |
Q64226690 | Identification of the Germline Mutation Profile in Esophageal Squamous Cell Carcinoma by Whole Exome Sequencing |
Q38412001 | Immunohistochemical analysis of p53, APE1, hMSH2 and ERCC1 proteins in actinic cheilitis and lip squamous cell carcinoma. |
Q90569921 | Immunohistochemical detection of the pro-apoptotic Bax∆2 protein in human tissues |
Q57168423 | Immunological-based approaches for cancer therapy |
Q41610925 | Impact of APEX Ile64val Gene Polymorphisms of DNA Repair Ber System on Modulation of the Risk of Colorectal Cancer in the Polish Population. |
Q28074585 | Impact of DNA mismatch repair system alterations on human fertility and related treatments |
Q36098562 | Improved multiplex ligation-dependent probe amplification analysis identifies a deleterious PMS2 allele generated by recombination with crossover between PMS2 and PMS2CL. |
Q41940321 | Insights into protein - DNA interactions, stability and allosteric communications: a computational study of mutSα-DNA recognition complexes |
Q35971310 | Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers |
Q33719300 | Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair. |
Q93134021 | Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer |
Q36828947 | Lessons learned from DNA repair defective syndromes |
Q37437757 | Low expression of MSH2 DNA repair protein is associated with poor prognosis in head and neck squamous cell carcinoma |
Q35636582 | Lymphangiogenesis is pivotal to the trials of a successful cancer metastasis |
Q36758454 | Lynch syndrome related endometrial cancer: clinical significance beyond the endometrium |
Q39870596 | MLH1 deficiency enhances tumor cell sensitivity to ganciclovir |
Q41908804 | MLH1-deficient HCT116 colon tumor cells exhibit resistance to the cytostatic and cytotoxic effect of the poly(A) polymerase inhibitor cordycepin (3'-deoxyadenosine) in vitro |
Q33933576 | MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer. |
Q36991032 | Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes |
Q37540260 | Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture). |
Q36564560 | Mechanisms in eukaryotic mismatch repair |
Q36315585 | Mechanisms of therapy-related carcinogenesis |
Q37373629 | Methylation Analysis of DNA Mismatch Repair Genes Using DNA Derived from the Peripheral Blood of Patients with Endometrial Cancer: Epimutation in Endometrial Carcinogenesis. |
Q46450790 | Methylnitrosourea as challenge mutagen in assessment of the DNA mismatch repair (MMR) activity: association with some types of cancer |
Q34808577 | MiRNAs as Biomarkers for Management of Patients With Colorectal Cancer |
Q46588821 | Microsatellite instability analysis of bilateral breast tumors suggests treatment-related origin of some contralateral malignancies. |
Q83835407 | Microsatellite instability as an indicator of malignant progression in laryngeal premalignancy |
Q44003216 | Microsatellite instability testing in Korean patients with colorectal cancer |
Q33252378 | Mismatch repair and treatment resistance in ovarian cancer |
Q38741029 | Mismatch repair deficiency testing in clinical practice |
Q41705634 | Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients |
Q37494397 | Mismatch repair genes in Lynch syndrome: a review |
Q37194167 | Mismatch repair protein deficiency compromises cisplatin-induced apoptotic signaling |
Q30569509 | Mismatch repair protein hMSH2-hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediate |
Q34362289 | Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN, and FOCUS studies |
Q64228131 | Mismatch repair status and high expression of PD-L1 in nasopharyngeal carcinoma |
Q41003050 | Mismatch repair status and synchronous metastases in colorectal cancer: A nationwide cohort study. |
Q37691675 | Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex |
Q38168515 | Modern aspects of the structural and functional organization of the DNA mismatch repair system |
Q27931842 | Modulation of the DNA-binding activity of Saccharomyces cerevisiae MSH2-MSH6 complex by the high-mobility group protein NHP6A, in vitro |
Q26747329 | Molecular Subtypes and Personalized Therapy in Metastatic Colorectal Cancer |
Q37710556 | Molecular Testing for Gastrointestinal Cancer. |
Q35915251 | Molecular basis and diagnostics of hereditary colorectal cancers |
Q37554315 | Molecular characteristics of mismatch repair genes in sporadic colorectal tumors in Czech patients |
Q96952383 | Molecular dissection of CRC primary tumors and their matched liver metastases reveals critical role of immune microenvironment, EMT and angiogenesis in cancer metastasis |
Q28383483 | Molecular epidemiology of DNA repair gene polymorphisms and head and neck cancer |
Q36422005 | Molecular mechanisms of cadmium induced mutagenicity |
Q36057058 | Molecular signaling mechanisms of apoptosis in hereditary non-polyposis colorectal cancer |
Q33579734 | Mouse models of colorectal cancer |
Q38271431 | Multiple factors insulate Msh2-Msh6 mismatch repair activity from defects in Msh2 domain I. |
Q44963326 | Multiple pilomatricomas with somatic CTNNB1 mutations in children with constitutive mismatch repair deficiency. |
Q58773528 | Must Peutz-Jeghers syndrome patients have the gene mutation? A case report and review of the literature |
Q33799870 | MutLalpha and proliferating cell nuclear antigen share binding sites on MutSbeta |
Q39758947 | MutSbeta exceeds MutSalpha in dinucleotide loop repair |
Q94543875 | Mutation analysis of related genes in hamartoma polyp tissue of Peutz-Jeghers syndrome |
Q35790060 | Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer |
Q27011117 | New insights and challenges in mismatch repair: getting over the chromatin hurdle |
Q28084645 | New insights into the mechanism of DNA mismatch repair |
Q41856985 | Non-specificity and synergy at the binding site of the carboplatin-induced DNA adduct via molecular dynamics simulations of the MutSα-DNA recognition complex. |
Q38421164 | Novel LOVD databases for hereditary breast cancer and colorectal cancer genes in the Chinese population |
Q35642022 | Novel MSH2 Mutation in the First Report of a Vietnamese-American Kindred with Lynch Syndrome |
Q35676307 | Novel aspects of macromolecular repair and relationship to human disease |
Q35829272 | Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1) |
Q36510713 | Optimizing the detection of hereditary non-polyposis colorectal cancer: an update. |
Q36988709 | Overexpression of MutSα Complex Proteins Predicts Poor Prognosis in Oral Squamous Cell Carcinoma |
Q33961620 | PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. |
Q38029584 | Pathological assessment of mismatch repair gene variants in Lynch syndrome: past, present, and future |
Q48375665 | Performance of Lynch syndrome predictive models in quantifying the likelihood of germline mutations in patients with abnormal MLH1 immunoexpression |
Q97524943 | Personalised mapping of tumour development in synchronous colorectal cancer patients |
Q34008793 | Pharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 years |
Q35590357 | Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis |
Q35111994 | Poly(ADP-ribose) polymerase inhibitors combined with external beam and radioimmunotherapy to treat aggressive lymphoma. |
Q36693272 | Poly(Adenosine diphosphate-ribose) polymerase inhibitors in cancer treatment |
Q34025252 | Premature aging and cancer in nucleotide excision repair-disorders |
Q37288374 | Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers |
Q38184378 | Prognostic biomarkers in colorectal cancer: where do we stand? |
Q37132721 | Prognostic value of colorectal cancer biomarkers. |
Q47733105 | Prognostic values of DNA mismatch repair genes in ovarian cancer patients treated with platinum-based chemotherapy. |
Q42613711 | Programmed death 1 blockade, an Achilles heel for MMR-deficient tumors? |
Q37056337 | Progress in the development of prognostic and predictive markers for gastrointestinal malignancies |
Q33201671 | Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis |
Q42911480 | Proteomic Analysis Reveals a Novel Mutator S (MutS) Partner Involved in Mismatch Repair Pathway. |
Q41858726 | Quantitative analysis of the effects of iododeoxyuridine and ionising radiation treatment on the cell cycle dynamics of DNA mismatch repair deficient human colorectal cancer cells |
Q89807855 | Rationale and design of the POLEM trial: avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III mismatch repair deficient or POLE exonuclease domain mutant colon cancer: a phase III randomised study |
Q33556873 | Reconstitution of Saccharomyces cerevisiae DNA polymerase ε-dependent mismatch repair with purified proteins |
Q35904200 | Regulation of UHRF1 by microRNA-9 modulates colorectal cancer cell proliferation and apoptosis |
Q36540486 | Regulation of mismatch repair by histone code and posttranslational modifications in eukaryotic cells |
Q36879506 | Regulation of therapeutic resistance in cancers by receptor tyrosine kinases |
Q36642662 | Relationship of lower uterine segment cancer with Lynch syndrome: a novel case with an hMLH1 germline mutation |
Q34397387 | Replication error deficient and proficient colorectal cancer gene expression differences caused by 3'UTR polyT sequence deletions |
Q54244033 | Role of hMLH1 and E-cadherin promoter methylation in gastric cancer progression. |
Q50765059 | SISE matters: the sum of information on seventy-yr-old equivalents measures pedigree information content when assessing the risk of HNPCC in a family. |
Q27931230 | Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs |
Q33640393 | Saccharomyces cerevisiae Msh2-Msh6 DNA binding kinetics reveal a mechanism of targeting sites for DNA mismatch repair |
Q46904587 | Screening of hub genes and pathways in colorectal cancer with microarray technology |
Q53267051 | Seeking the driver in tumours with apparent normal molecular profile on comparative genomic hybridization and targeted gene panel sequencing: what is the added value of whole exome sequencing? |
Q39984449 | Selective sensitivity to carboxyamidotriazole by human tumor cell lines with DNA mismatch repair deficiency |
Q34167290 | Single nucleotide polymorphisms of DNA mismatch repair genes MSH2 and MLH1 confer susceptibility to esophageal cancer |
Q39148893 | Stable expression of MutLγ in human cells reveals no specific response to mismatched DNA, but distinct recruitment to damage sites. |
Q36171056 | Stakeholder perspectives on implementing a universal Lynch syndrome screening program: a qualitative study of early barriers and facilitators. |
Q57784305 | Stochastic Processes and Component Plasticity Governing DNA Mismatch Repair |
Q37592729 | Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair |
Q27667527 | Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family |
Q27650171 | Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase λ |
Q36574973 | Syndromes with genetic instability: model diseases for (skin) cancerogenesis |
Q38834760 | Targeting deficient DNA damage repair in gastric cancer. |
Q38718010 | Temozolomide in the Era of Precision Medicine |
Q35732828 | The CREB Coactivator CRTC2 Is a Lymphoma Tumor Suppressor that Preserves Genome Integrity through Transcription of DNA Mismatch Repair Genes |
Q33557369 | The Emerging Role of PARP Inhibitors in the Treatment of Epithelial Ovarian Cancer |
Q97527458 | The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability |
Q30234889 | The Rising Incidence of Younger Patients With Colorectal Cancer: Questions About Screening, Biology, and Treatment |
Q47620321 | The Smad4/PTEN Expression Pattern Predicts Clinical Outcomes in Colorectal Adenocarcinoma |
Q55153904 | The coming of age: immunotherapy in gastrointestinal malignancies. |
Q41860625 | The effects of nucleotides on MutS-DNA binding kinetics clarify the role of MutS ATPase activity in mismatch repair |
Q38195175 | The emerging roles of ARID1A in tumor suppression |
Q35746647 | The hMLH1 -93G>A Polymorphism and Risk of Ovarian Cancer in the Chinese Population |
Q24339204 | The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα |
Q42934262 | The mismatch repair and base excision repair pathways: an opportunity for individualized (personalized) sensitization of cancer therapy |
Q42225975 | The molecular origin of the MMR-dependent apoptosis pathway from dynamics analysis of MutSα-DNA complexes |
Q36448284 | The multifaceted mismatch-repair system |
Q37983690 | The potential of exploiting DNA-repair defects for optimizing lung cancer treatment |
Q35818437 | The role of intracellular calcium for the development and treatment of neuroblastoma |
Q42572300 | The role of nucleotide cofactor binding in cooperativity and specificity of MutS recognition |
Q35904483 | The utility of immunohistochemical detection of DNA mismatch repair gene proteins. |
Q33298821 | Three novel missense germline mutations in different exons of MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families |
Q38397338 | Tissue expression of MLH1, PMS2, MSH2, and MSH6 proteins and prognostic value of microsatellite instability in Wilms tumor: experience of 45 cases. |
Q37978580 | Tumor spectrum in lynch syndrome, DNA mismatch repair system and endogenous carcinogens |
Q53519387 | Universal screening for Lynch syndrome among patients with colorectal cancer: patient perspectives on screening and sharing results with at-risk relatives. |
Q33283854 | Untangling the relationships between DNA repair pathways by silencing more than 20 DNA repair genes in human stable clones. |
Q36990046 | Update on Lynch syndrome genomics |
Q52643529 | Updates on immunotherapy for colorectal cancer. |
Q59272977 | Uroepithelial and kidney carcinoma in Lynch syndrome |
Q36246500 | Use of microsatellite instability and immunohistochemistry testing for the identification of individuals at risk for Lynch syndrome |
Q50711835 | Very high incidence of familial colorectal cancer in Newfoundland: a comparison with Ontario and 13 other population-based studies. |
Q36338245 | Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates. |
Q33852069 | Vitamin E Modifies High-Fat Diet-Induced Increase of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice. |
Q97644556 | Workflow for the Implementation of Precision Genomics in Healthcare |
Q80558791 | [Colorectal carcinogenesis. 2. Underlying epigenetic and genetic alterations and molecular classification of colorectal cancers] |
Q36103305 | mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer |
Q33726141 | miR-1290 Is a Biomarker in DNA-Mismatch-Repair-Deficient Colon Cancer and Promotes Resistance to 5-Fluorouracil by Directly Targeting hMSH2. |
Q36028209 | p53: traffic cop at the crossroads of DNA repair and recombination |
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