Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression

scientific article

Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1007441723
P356DOI10.1186/1471-2407-9-25
P932PMC publication ID2647942
P698PubMed publication ID19154585
P5875ResearchGate publication ID23802448

P2093author name stringBen Vainer
Søren A Jensen
Mogens Kruhøffer
Jens B Sørensen
P2860cites workPrognostic significance of microsatellite instability in sporadic colorectal cancer.Q53639179
Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors.Q54628312
Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapyQ57567897
Genetic heterogeneity of variable number tandem repeats in thymidylate synthase gene in colorectal cancer patientsQ63884150
Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patientsQ72313890
Tumor microsatellite instability and clinical outcome in young patients with colorectal cancerQ73345126
Microsatellite instabilityQ73683104
Proliferation, apoptosis, and survival in high-level microsatellite instability sporadic colorectal cancerQ74321037
Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative StudyQ79572431
Detection of thymidylate synthase expression in lymph node metastases of colorectal cancer can improve the prognostic informationQ80357673
Reduced likelihood of metastases in patients with microsatellite-unstable colorectal cancerQ80557773
Thymidylate synthase expression in colon carcinomas with microsatellite instabilityQ83289136
High thymidylate synthase expression is typical for sporadic MSI-H colorectal carcinomaQ83892137
Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancerQ24614511
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instabilityQ24618618
Cancer statistics, 2001Q28189339
Systematic review of microsatellite instability and colorectal cancer prognosisQ28303189
Molecular predictors of survival after adjuvant chemotherapy for colon cancerQ28363159
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinomaQ29615026
Inter-relationship between microsatellite instability, thymidylate synthase expression, and p53 status in colorectal cancer: implications for chemoresistanceQ33245747
Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancerQ33930691
Thymidylate synthase expression in stage II and III colon cancer: a retrospective reviewQ34501075
Mismatch repair proficiency and in vitro response to 5-fluorouracilQ35129256
Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysisQ35643092
Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancerQ35760529
The prognostic significance of thymidylate synthase and dihydropyrimidine dehydrogenase in colorectal cancer of 303 patients adjuvantly treated with 5-fluorouracilQ38435280
Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors-correlation to tumor histopathology and clinical follow-upQ38441178
Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancerQ38449001
Prevalence and prognostic role of microsatellite instability in patients with rectal carcinomaQ38455394
Prognostic and predictive value of the thymidylate synthase expression in patients with non-metastatic colorectal cancerQ40418496
Microsatellite instability is a predictive marker for survival benefit from adjuvant chemotherapy in a population-based series of stage III colorectal carcinomaQ40620362
Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR.Q40687159
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeastQ42427955
Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancerQ43722882
Thymidylate synthase expression in colorectal cancer: a prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapyQ43937145
The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancerQ43960974
Retrospective study on thymidylate synthase as a predictor of outcome and sensitivity to adjuvant chemotherapy in patients with curatively resected colorectal cancerQ44190145
DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular studyQ44210955
Clinicopathological and molecular biological features of colorectal cancer in patients less than 40 years of age.Q44295097
Tumor dihydropyrimidine dehydrogenase in stage II and III colorectal cancer: low level expression is a beneficial marker in oral-adjuvant chemotherapy, but is also a predictor for poor prognosis in patients treated with curative surgery aloneQ44742955
Survival after adjuvant 5-FU treatment for stage III colon cancer in hereditary nonpolyposis colorectal cancer.Q44763095
Associations between polymorphisms in the thymidylate synthase gene, the expression of thymidylate synthase mRNA and the microsatellite instability phenotype of colorectal cancer.Q44793209
Thymidylate synthase gene promoter polymorphisms are associated with TSmRNA expressions but not with microsatellite instability in colorectal cancer.Q45286673
Thymidylate synthase polymorphisms and colon cancer: associations with tumor stage, tumor characteristics and survival.Q45957330
High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategiesQ46522716
Microsatellite instability and colorectal cancer prognosis.Q46831092
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
microsatelliteQ265193
colorectal carcinomaQ25493920
P304page(s)25
P577publication date2009-01-20
P1433published inBMC CancerQ326300
P1476titleMicrosatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression
P478volume9

Reverse relations

cites work (P2860)
Q39422383ARNTL2 and SERPINE1: potential biomarkers for tumor aggressiveness in colorectal cancer.
Q36473730Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis
Q53440447Association between mismatch repair gene and irinotecan-based chemotherapy in metastatic colon cancer.
Q37708008Circadian clock circuitry in colorectal cancer
Q43048728Correlation between thymidylate synthase gene variants, RNA and protein levels in primary colorectal adenocarcinomas
Q35773077Distinct gene expression profiles of proximal and distal colorectal cancer: implications for cytotoxic and targeted therapy.
Q58407923Frequent intragenic rearrangements of DPYD in colorectal tumours
Q38732716High microsatellite instability (MSI-H) colorectal carcinoma: a brief review of predictive biomarkers in the era of personalized medicine
Q37581999Impact of microsatellite status on chemotherapy for colorectal cancer patients with KRAS or BRAF mutation
Q34521714Multifaceted enrichment analysis of RNA-RNA crosstalk reveals cooperating micro-societies in human colorectal cancer
Q36964450Personalized medicine and oncology practice guidelines: a case study of contemporary biomarkers in colorectal cancer
Q58583909Prognostic Value of Mismatch Repair Genes for Patients With Colorectal Cancer: Meta-Analysis
Q26830362Prognostic and predictive markers in stage II colon cancer: is there a role for gene expression profiling?
Q35925275Reflex immunohistochemistry and microsatellite instability testing of colorectal tumors for Lynch syndrome among US cancer programs and follow-up of abnormal results
Q37137372Sputum-based molecular biomarkers for the early detection of lung cancer: limitations and promise
Q90295780The Prognostic and Predictive Value of Dihydropyrimidine Dehydrogenase-Related Indicators in Clinical Outcomes of Chemotherapy in Colorectal Cancer Patients: a Systematic Review and Meta-Analysis
Q44785500Thymidilate synthase expression predicts longer survival in patients with stage II colon cancer treated with 5-flurouracil independently of microsatellite instability.

Search more.