Genomic Instability Induced by Mutations in Saccharomyces cerevisiae POL1

scientific article published on September 1, 2003

Genomic Instability Induced by Mutations in Saccharomyces cerevisiae POL1 is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/GENETICS/165.1.65
P953full work available at URLhttps://academic.oup.com/genetics/article-pdf/165/1/65/37273943/genetics0065.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/14504218/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/14504218/pdf/?tool=EBI
http://intl.genetics.org/cgi/content/abstract/165/1/65
https://europepmc.org/articles/PMC1462734
https://europepmc.org/articles/PMC1462734?pdf=render
https://academic.oup.com/genetics/article-pdf/165/1/65/42051818/genetics0065.pdf
P932PMC publication ID1462734
P698PubMed publication ID14504218

P50authorTeresa WangQ110990964
P2093author name stringTeresa S-F Wang
Pedro J. A. Gutiérrez
P2860cites workHypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.Q36568353
Mutational effect of fission yeast polalpha on cell cycle eventsQ36897524
Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genesQ37599112
Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase deltaQ39455847
Mutator phenotype induced by aberrant replicationQ39610863
Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genesQ40022200
Instability of simple sequence DNA in Saccharomyces cerevisiaeQ40655124
An attempt to unify the structure of polymerasesQ41204694
Mutational studies of human DNA polymerase alpha. Lysine 950 in the third most conserved region of alpha-like DNA polymerases is involved in binding the deoxynucleoside triphosphateQ42065679
Fidelity studies of the human DNA polymerase alpha. The most conserved region among alpha-like DNA polymerases is responsible for metal-induced infidelity in DNA synthesis.Q43757735
DNA replication checkpointQ46141669
Nucleotide sequence and characterization of temperature-sensitive pol1 mutants of Saccharomyces cerevisiaeQ63383483
Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta.Q64988940
Putting the HO gene to work: practical uses for mating-type switchingQ70120801
Identification of a Ty insertion within the coding sequence of the S. cerevisiae URA3 geneQ70198682
Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stabilityQ71081409
The 3'-->5' exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiaeQ72240900
In vivo species specificity of DNA polymerase alphaQ72623776
Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturationQ73911234
Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitroQ24319018
Structure of the replicating complex of a pol alpha family DNA polymeraseQ27632340
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69Q27740210
A generic protein purification method for protein complex characterization and proteome explorationQ27861087
Double-strand break repair in yeast requires both leading and lagging strand DNA polymerasesQ27934176
Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repairQ27938608
The DNA replication fork in eukaryotic cells.Q27939216
Getting started with yeastQ28131602
5-Fluoroorotic acid as a selective agent in yeast molecular geneticsQ28131614
DNA replication in eukaryotic cellsQ28131747
Reconstitution of complete SV40 DNA replication with purified replication factorsQ28251397
Pathway correcting DNA replication errors in Saccharomyces cerevisiaeQ28263175
In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zetaQ28354217
Quality control by DNA repairQ28608962
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repairQ29615027
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repairQ29618879
The distribution of the numbers of mutants in bacterial populationsQ29620123
DNA polymerase I gene of Saccharomyces cerevisiae: nucleotide sequence, mapping of a temperature-sensitive mutation, and protein homology with other DNA polymerasesQ33576785
Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).Q33786528
Mutations in POL1 increase the mitotic instability of tandem inverted repeats in Saccharomyces cerevisiaeQ33960923
The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasisQ33961700
Destabilization of simple repetitive DNA sequences by transcription in yeast.Q33967667
The prevention of repeat-associated deletions in Saccharomyces cerevisiae by mismatch repair depends on size and origin of deletions.Q33968093
Microsatellite Instability in Yeast: Dependence on the Length of the MicrosatelliteQ33970339
Cell-cycle checkpoint kinases: checking in on the cell cycleQ34076838
Characterization of the repeat-tract instability and mutator phenotypes conferred by a Tn3 insertion in RFC1, the large subunit of the yeast clamp loaderQ34606398
A DNA polymerase epsilon mutant that specifically causes +1 frameshift mutations within homonucleotide runs in yeastQ34610131
Temperature-sensitive mutations in the yeast DNA polymerase I geneQ34618611
Replication proteins influence the maintenance of telomere length and telomerase protein stabilityQ34930176
Compilation and alignment of DNA polymerase sequencesQ35774285
Checkpoint activation regulates mutagenic translesion synthesisQ35963618
Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes.Q36555338
Altered replication and inverted repeats induce mismatch repair-independent recombination between highly diverged DNAs in yeast.Q36565513
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectSaccharomyces cerevisiaeQ719725
geneticsQ7162
genome instabilityQ2892636
P304page(s)65-81
P577publication date2003-09-01
P1433published inGeneticsQ3100575
P1476titleGenomic Instability Induced by Mutations in Saccharomyces cerevisiae POL1
P478volume165

Reverse relations

cites work (P2860)
Q37574087A coordinated temporal interplay of nucleosome reorganization factor, sister chromatin cohesion factor, and DNA polymerase alpha facilitates DNA replication
Q35040027A novel function of DNA polymerase zeta regulated by PCNA.
Q90047387Defective DNA Polymerase α-Primase Leads to X-Linked Intellectual Disability Associated with Severe Growth Retardation, Microcephaly, and Hypogonadism
Q27933645Defective interaction between Pol2p and Dpb2p, subunits of DNA polymerase epsilon, contributes to a mutator phenotype in Saccharomyces cerevisiae
Q35834445Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing
Q48100066Long repeats in a huge genome: microsatellite loci in the grasshopper Chorthippus biguttulus
Q33347123Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae.
Q42248736Mcm10 deficiency causes defective-replisome-induced mutagenesis and a dependency on error-free postreplicative repair.
Q27937434Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε.
Q37483304Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools
Q33751481Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress
Q39657744Replication-compromised cells require the mitotic checkpoint to prevent tetraploidization
Q37310667Retrotransposon overdose and genome integrity.
Q42467404The role of DNA polymerase alpha in the control of mutagenesis in Saccharomyces cerevisiae cells starved for nutrients
Q34123401Ubc4 and Not4 regulate steady-state levels of DNA polymerase-α to promote efficient and accurate DNA replication.

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