| scholarly article | Q13442814 |
| P2093 | author name string | Michael Lynch | |
| P2860 | cites work | Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6 | Q22242924 |
| The Average Number of Generations until Fixation of a Mutant Gene in a Finite Population. | Q24533352 | ||
| Evolvability is a selectable trait | Q24564104 | ||
| Evolution of the mutation rate | Q24602069 | ||
| Mechanism and evolution of DNA primases | Q24612068 | ||
| Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs | Q27931230 | ||
| Unique error signature of the four-subunit yeast DNA polymerase epsilon | Q27935855 | ||
| A constant rate of spontaneous mutation in DNA-based microbes | Q28271032 | ||
| Thymic lymphomas arising in Msh2 deficient mice display a large increase in mutation frequency and an altered mutational spectrum | Q28591339 | ||
| Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells | Q28592033 | ||
| Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair | Q29615027 | ||
| The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. | Q30408086 | ||
| Functional analysis of the Bacillus subtilis y shD gene, a mutS paralogue | Q42645174 | ||
| Role of mutS and mutL genes in hypermutability and recombination in Staphylococcus aureus | Q42754912 | ||
| Mismatch repair and the regulation of phase variation in Neisseria meningitidis | Q43612705 | ||
| A hypermutator phenotype attenuates the virulence of Listeria monocytogenes in a mouse model | Q43982282 | ||
| Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases | Q44705872 | ||
| Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies | Q46320742 | ||
| The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria | Q46347662 | ||
| Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions. | Q46554910 | ||
| Purification and properties of wild-type and exonuclease-deficient DNA polymerase II from Escherichia coli | Q46595699 | ||
| Effect of Escherichia coli dnaE antimutator mutants on mutagenesis by the base analog N4-aminocytidine. | Q54130748 | ||
| Mutation rate is reduced by increased dosage of mutL gene in Escherichia coli K-12. | Q54434792 | ||
| Role of mutator alleles in adaptive evolution. | Q54564129 | ||
| Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli. | Q54648245 | ||
| The cost of replication fidelity in human immunodeficiency virus type 1. | Q55430533 | ||
| No evidence for elemental-based streamlining of prokaryotic genomes | Q57618425 | ||
| DNA replication errors produced by the replicative apparatus of Escherichia coli. | Q64994677 | ||
| The accumulation of deleterious genes in a population--Muller's Ratchet | Q67444775 | ||
| Accuracy of DNA primase | Q68632530 | ||
| The age of an allele in a finite population | Q68799539 | ||
| General antimutators are improbable | Q70532050 | ||
| Molecular analysis of mutations in mutator colorectal carcinoma cell lines | Q70972736 | ||
| Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability | Q71081409 | ||
| Misincorporation of nucleotides by calf thymus DNA primase and elongation of primers containing multiple noncognate nucleotides by DNA polymerase alpha | Q72068723 | ||
| The approach to mutation-selection balance in an infinite asexual population, and the evolution of mutation rates | Q73373285 | ||
| Hypermutability to ionizing radiation in mismatch repair-deficient, Pms2 knockout mice | Q73812953 | ||
| Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae | Q74478617 | ||
| Complementation of mismatch repair gene defects by chromosome transfer | Q74801797 | ||
| The dynamics of infinitesimally rare alleles, applied to the evolution of mutation rates and the expression of deleterious mutations | Q77928374 | ||
| Fidelity of DNA polymerase delta holoenzyme from Saccharomyces cerevisiae: the sliding clamp proliferating cell nuclear antigen decreases its fidelity | Q79326276 | ||
| Highly tolerated amino acid substitutions increase the fidelity of Escherichia coli DNA polymerase I. | Q33273825 | ||
| Optimization of DNA polymerase mutation rates during bacterial evolution | Q33667067 | ||
| The cost of replication fidelity in an RNA virus | Q33900476 | ||
| Evolution-driving genes | Q33949870 | ||
| Mutants of Escherichia coli with increased fidelity of DNA replication | Q33961314 | ||
| Probability of fixation and mean fixation time of an overdominant mutation | Q33988967 | ||
| Functions of the mismatch repair gene mutS from Acinetobacter sp. strain ADP1. | Q33997106 | ||
| Second-order selection in bacterial evolution: selection acting on mutation and recombination rates in the course of adaptation | Q34203956 | ||
| Evolving responsively: adaptive mutation | Q34297067 | ||
| Quantitative relationships for specific growth rates and macromolecular compositions of Mycobacterium tuberculosis, Streptomyces coelicolor A3(2) and Escherichia coli B/r: an integrative theoretical approach | Q34319498 | ||
| Evolution of high mutation rates in experimental populations of E. coli | Q34429727 | ||
| High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection. | Q34508854 | ||
| Processivity clamp gp45 and ssDNA-binding-protein gp32 modulate the fidelity of bacteriophage RB69 DNA polymerase in a sequence-specific manner, sometimes enhancing and sometimes compromising accuracy | Q34572723 | ||
| Antimutator mutants in bacteriophage T4 and Escherichia coli | Q34603796 | ||
| Functional overlap in mismatch repair by human MSH3 and MSH6. | Q34603929 | ||
| Beneficial mutations, hitchhiking and the evolution of mutation rates in sexual populations | Q34606746 | ||
| Genome-wide patterns of nucleotide substitution reveal stringent functional constraints on the protein sequences of thermophiles | Q34645289 | ||
| Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta. | Q35728727 | ||
| Complete genetic linkage can subvert natural selection | Q35748721 | ||
| Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon. | Q35837411 | ||
| Mutation as a stress response and the regulation of evolvability | Q35869358 | ||
| Mismatch repair genes of Streptococcus pneumoniae: HexA confers a mutator phenotype in Escherichia coli by negative complementation | Q36165935 | ||
| Spontaneously Arising mutL Mutators in Evolving Escherichia coli Populations Are the Result of Changes in Repeat Length | Q36474342 | ||
| Hypermutable bacteria isolated from humans--a critical analysis | Q36583214 | ||
| Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene | Q36643609 | ||
| Mutation rate variation in multicellular eukaryotes: causes and consequences | Q36885382 | ||
| The cellular, developmental and population-genetic determinants of mutation-rate evolution | Q36936869 | ||
| Stress-induced mutagenesis in bacteria. | Q36961683 | ||
| The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases delta and eta. | Q37199504 | ||
| Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes | Q40022200 | ||
| The diverse and dynamic structure of bacterial genomes | Q40826162 | ||
| A symmetry of fixation times in evoultionary dynamics | Q40847725 | ||
| The mutational meltdown in asexual populations | Q41067565 | ||
| Mutation rate at the hprt locus in human cancer cell lines with specific mismatch repair-gene defects | Q41140973 | ||
| MUTATION LOAD AND THE SURVIVAL OF SMALL POPULATIONS. | Q41176863 | ||
| Selection against hypermutability in Escherichia coli during long term evolution | Q41568929 | ||
| The enhanced DNA replication fidelity of a mutant herpes simplex virus type 1 DNA polymerase is mediated by an improved nucleotide selectivity and reduced mismatch extension ability | Q42028762 | ||
| The degeneration of asexual haploid populations and the speed of Muller's ratchet | Q42122982 | ||
| Pms2 deficiency results in increased mutation in the Hprt gene but not the Tk gene of Tk(+/-) transgenic mice. | Q42163621 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial 3.0 Unported | Q18810331 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1107-1118 | |
| P577 | publication date | 2011-08-04 | |
| P1433 | published in | Genome Biology and Evolution | Q15817736 |
| P1476 | title | The lower bound to the evolution of mutation rates | |
| P478 | volume | 3 |
| Q40230898 | Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli |
| Q89051609 | Alternative Polyadenylation of Mammalian Transcripts Is Generally Deleterious, Not Adaptive |
| Q34047307 | Animal Mitochondrial DNA as We Do Not Know It: mt-Genome Organization and Evolution in Nonbilaterian Lineages. |
| Q88961034 | Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice |
| Q92963637 | Clonal evolution and genome stability in a 2500-year-old fungal individual |
| Q41255353 | Contribution of increased mutagenesis to the evolution of pollutants-degrading indigenous bacteria |
| Q41926021 | Correlation between mutation rate and genome size in riboviruses: mutation rate of bacteriophage Qβ. |
| Q39202518 | DNA sequence diversity and the efficiency of natural selection in animal mitochondrial DNA. |
| Q38859901 | Delayed lysis confers resistance to the nucleoside analogue 5-fluorouracil and alleviates mutation accumulation in the single-stranded DNA bacteriophage ϕX174. |
| Q40041222 | Different rates of spontaneous mutation of chloroplastic and nuclear viroids as determined by high-fidelity ultra-deep sequencing |
| Q28597909 | Direct estimate of the rate of germline mutation in a bird |
| Q57153482 | Direct estimation of the spontaneous mutation rate by short-term mutation accumulation lines in |
| Q55311733 | Do plants have a segregated germline? |
| Q37557672 | Domestication and the mitochondrial genome: comparing patterns and rates of molecular evolution in domesticated mammals and birds and their wild relatives |
| Q36389558 | Drift-barrier hypothesis and mutation-rate evolution. |
| Q40520895 | Effect of mismatch repair on the mutation rate of bacteriophage ϕX174. |
| Q92962817 | Elevated mutation rates are unlikely to evolve in sexual species, not even under rapid environmental change |
| Q101574097 | Enhanced risk of cancer in companion animals as a response to the longevity |
| Q42277813 | Estimate of the spontaneous mutation rate in Chlamydomonas reinhardtii |
| Q42741265 | Evolution of Mutation Rates in Rapidly Adapting Asexual Populations. |
| Q27499250 | Evolution of eye development in the darkness of caves: adaptation, drift, or both? |
| Q31095701 | Evolution of microbes and viruses: a paradigm shift in evolutionary biology? |
| Q37163055 | Evolution of the Insertion-Deletion Mutation Rate Across the Tree of Life. |
| Q34661508 | Evolutionary cell biology: two origins, one objective |
| Q36414697 | Evolutionary layering and the limits to cellular perfection |
| Q34926385 | Evolutionary meandering of intermolecular interactions along the drift barrier |
| Q36437010 | Extraordinary genome stability in the ciliate Paramecium tetraurelia |
| Q41778880 | Fixation probability of rare nonmutator and evolution of mutation rates |
| Q38980350 | Genetic drift, selection and the evolution of the mutation rate |
| Q37136035 | Genetics: Feedforward loop for diversity |
| Q40540697 | Genome-Wide Biases in the Rate and Molecular Spectrum of Spontaneous Mutations in Vibrio cholerae and Vibrio fischeri |
| Q48000401 | Genomewide mutation dynamic within a long-lived individual of Armillaria gallica |
| Q55285004 | High mutation rates limit evolutionary adaptation in Escherichia coli. |
| Q36098230 | Inevitability of genetic parasites |
| Q31155069 | Inference of Candidate Germline Mutator Loci in Humans from Genome-Wide Haplotype Data |
| Q35027571 | Large-scale detection of in vivo transcription errors |
| Q91734797 | Mitochondrial DNA: the overlooked oncogenome? |
| Q46296390 | Mutation Rate Evolution in Partially Selfing and Partially Asexual Organisms |
| Q28389468 | Mutation and Human Exceptionalism: Our Future Genetic Load |
| Q36406079 | Nascent RNA folding mitigates transcription-associated mutagenesis |
| Q36935351 | No gene-specific optimization of mutation rate in Escherichia coli |
| Q38071050 | Non-random mutation: the evolution of targeted hypermutation and hypomutation |
| Q34351963 | Parasitic plants have increased rates of molecular evolution across all three genomes |
| Q55438253 | Phylogenetic divergence of cell biological features. |
| Q38154687 | Population size and the rate of evolution. |
| Q42778187 | RNA polymerase errors cause splicing defects and can be regulated by differential expression of RNA polymerase subunits |
| Q33699821 | Rapid evolution of the human mutation spectrum |
| Q37007856 | Recent Selection Changes in Human Genes under Long-Term Balancing Selection |
| Q21145734 | Revisiting an old riddle: what determines genetic diversity levels within species? |
| Q36342935 | Sex, prions, and plasmids in yeast |
| Q64241400 | Significant Strain Variation in the Mutation Spectra of Inbred Laboratory Mice |
| Q92827050 | Somatic maintenance impacts the evolution of mutation rate |
| Q37063149 | Stabilizing selection, purifying selection, and mutational bias in finite populations |
| Q28080115 | The Evolution of Per-cell Organelle Number |
| Q35882379 | The Rate and Molecular Spectrum of Spontaneous Mutations in the GC-Rich Multichromosome Genome of Burkholderia cenocepacia |
| Q37079602 | The Rate and Spectrum of Spontaneous Mutations in Mycobacterium smegmatis, a Bacterium Naturally Devoid of the Postreplicative Mismatch Repair Pathway |
| Q35919899 | The evolution of multimeric protein assemblages |
| Q35579831 | The evolutionarily stable distribution of fitness effects |
| Q35900342 | The repatterning of eukaryotic genomes by random genetic drift |
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