Lethal mutagenesis of bacteria

scientific article (publication date: October 2008)

Lethal mutagenesis of bacteria is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1534/GENETICS.108.091413
P932PMC publication ID2567356
P698PubMed publication ID18780744
P5875ResearchGate publication ID23246518

P50authorClaus O. WilkeQ30388859
P2093author name stringJames J Bull
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Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivityQ27470003
Ribavirin Reveals a Lethal Threshold of Allowable Mutation Frequency for Hantaan VirusQ27484998
Evolution of digital organisms at high mutation rates leads to survival of the flattestQ28207333
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Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodiesQ30841593
Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteinsQ33216570
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Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexityQ34190672
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A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelityQ35163547
Genomic Instability and CancerQ35577228
Lethal mutagens: broad-spectrum antivirals with limited potential for development of resistance?Q35741477
Complete genetic linkage can subvert natural selectionQ35748721
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Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implicationsQ36008885
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Protein stability imposes limits on organism complexity and speed of molecular evolutionQ36092556
Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.Q36099285
Mechanisms of action of ribavirin against distinct virusesQ36312805
Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.Q36482715
Generation of large libraries of random mutants in Bacillus subtilis by PCR-based plasmid multimerizationQ36877947
Selection for fitness versus selection for robustness in RNA secondary structure foldingQ39593341
Selection for mutational robustness in finite populationsQ39765259
The traveling-wave approach to asexual evolution: Muller's ratchet and speed of adaptationQ41853709
Theory of lethal mutagenesis for virusesQ41979840
Estimate of the genomic mutation rate deleterious to overall fitness in E. coli.Q51030744
Application of logistic growth model to pharmacodynamic analysis of in vitro bactericidal kinetics.Q52183791
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)1061-70
P577publication date2008-10-01
P1433published inGeneticsQ3100575
P1476titleLethal mutagenesis of bacteria
P478volume180

Reverse relations

cites work (P2860)
Q47446328Arresting Evolution
Q28727500Cancer in light of experimental evolution
Q42736352Competition between high- and higher-mutating strains of Escherichia coli
Q50107946DNA Replication Fidelity in the Mycobacterium tuberculosis Complex
Q35012141Diploidy and the selective advantage for sexual reproduction in unicellular organisms
Q28474346Does mutational robustness inhibit extinction by lethal mutagenesis in viral populations?
Q53566921Dynamics and Fate of Beneficial Mutations Under Lineage Contamination by Linked Deleterious Mutations.
Q37194798Empirical complexities in the genetic foundations of lethal mutagenesis
Q33628435Evolution at a high imposed mutation rate: adaptation obscures the load in phage T7
Q58429559Evolution models with lethal mutations on symmetric or random fitness landscapes
Q33704988Genomic mutation rates that neutralize adaptive evolution and natural selection
Q55285004High mutation rates limit evolutionary adaptation in Escherichia coli.
Q35669158Lethal Mutagenesis: Targeting the Mutator Phenotype in Cancer
Q40863246Lethal mutagenesis and evolutionary epidemiology
Q40471201Lethal mutagenesis in a structured environment.
Q37397484Lethal mutagenesis in viruses and bacteria
Q33351929Lethal mutants and truncated selection together solve a paradox of the origin of life
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Q91902524Mutation bias and GC content shape antimutator invasions
Q34372268Mutation induced extinction in finite populations: lethal mutagenesis and lethal isolation
Q31016944Mutator dynamics in sexual and asexual experimental populations of yeast

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