| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Claude-Agnès Reynaud | Q21257492 |
| P2093 | author name string | Jean-Claude Weill | |
| P2860 | cites work | hRAD30 mutations in the variant form of xeroderma pigmentosum | Q22010237 |
| Eukaryotic DNA Polymerases | Q22065416 | ||
| Two novel human and mouse DNA polymerases of the polX family | Q24290234 | ||
| Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2) | Q24290325 | ||
| Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination | Q24294409 | ||
| SOS-induced DNA polymerases enhance long-term survival and evolutionary fitness | Q24530758 | ||
| The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation | Q24537096 | ||
| Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair | Q24540101 | ||
| High-efficiency bypass of DNA damage by human DNA polymerase Q | Q24561381 | ||
| Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis | Q24594244 | ||
| The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis | Q24794355 | ||
| Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate | Q24802780 | ||
| Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. | Q27919645 | ||
| A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining | Q27919680 | ||
| Deoxycytidyl transferase activity of yeast REV1 protein | Q27931173 | ||
| Evidence that the long murine terminal deoxynucleotidyltransferase isoform plays no role in the control of V(D)J junctional diversity. | Q42828788 | ||
| Lesion bypass activities of human DNA polymerase mu. | Q44135115 | ||
| Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice | Q44194766 | ||
| Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene | Q45345090 | ||
| Somatic mutation of immunoglobulin light-chain variable-region genes | Q48409137 | ||
| Disruption of the developmentally regulated Rev3l gene causes embryonic lethality. | Q52163744 | ||
| Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro. | Q52541352 | ||
| Disruption of the Rev3l-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality. | Q52541355 | ||
| Variability in the Lambda Light Chain Sequences of Mouse Antibody | Q52832029 | ||
| IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts | Q54526958 | ||
| Role of mutator alleles in adaptive evolution. | Q54564129 | ||
| The absence of DNA polymerase kappa does not affect somatic hypermutation of the mouse immunoglobulin heavy chain gene. | Q54777328 | ||
| Somatic mutation and the maturation of immune response to 2-phenyl oxazolone | Q58019387 | ||
| Decreased Frequency of Somatic Hypermutation and Impaired Affinity Maturation but Intact Germinal Center Formation in Mice Expressing Antisense RNA to DNA Polymerase | Q58424602 | ||
| Origin of Antibody Variation | Q59057486 | ||
| 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins | Q59075328 | ||
| DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes | Q80194521 | ||
| Strand-biased spreading of mutations during somatic hypermutation | Q80970581 | ||
| Uracil DNA glycosylase disruption blocks Ig gene conversion and induces transition mutations | Q40338305 | ||
| Dual roles for DNA polymerase eta in homologous DNA recombination and translesion DNA synthesis | Q40342097 | ||
| Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination | Q40342102 | ||
| DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells | Q40410915 | ||
| Mutational analysis of terminal deoxynucleotidyltransferase-mediated N-nucleotide addition in V(D)J recombination | Q40564340 | ||
| AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line | Q40714843 | ||
| AID is essential for immunoglobulin V gene conversion in a cultured B cell line | Q40746479 | ||
| Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion | Q40750743 | ||
| The structural repertoire of the human V kappa domain | Q40789466 | ||
| TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line | Q40982321 | ||
| Clonal selection and learning in the antibody system | Q41002744 | ||
| Rearrangement/hypermutation/gene conversion: when, where and why? | Q41113095 | ||
| Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice | Q41807812 | ||
| Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Pol4)-dependent pathway | Q27938668 | ||
| The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta | Q28115711 | ||
| Genes and antibodies | Q28185156 | ||
| DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes | Q28190856 | ||
| Marginal-zone B cells | Q28201000 | ||
| Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu | Q28202970 | ||
| Error rate and specificity of human and murine DNA polymerase eta | Q28216092 | ||
| Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo | Q28253487 | ||
| DNA joint dependence of pol X family polymerase action in nonhomologous end joining | Q28257407 | ||
| PCNA binding through a conserved motif | Q28274063 | ||
| PCNA, the maestro of the replication fork | Q28303101 | ||
| Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice | Q28505784 | ||
| DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes | Q28506592 | ||
| Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells | Q28509339 | ||
| Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern | Q28510640 | ||
| Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice | Q28513971 | ||
| Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation | Q28586304 | ||
| DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis | Q28586606 | ||
| 129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation | Q28587504 | ||
| Distinct and opposite diversifying activities of terminal transferase splice variants | Q28587746 | ||
| Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally | Q28592782 | ||
| Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes | Q28594477 | ||
| Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro | Q28646677 | ||
| Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion | Q28646698 | ||
| Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage | Q28646728 | ||
| Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme | Q29547201 | ||
| Somatic generation of antibody diversity | Q29616439 | ||
| Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function | Q29617871 | ||
| Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis | Q29619757 | ||
| Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions | Q29619958 | ||
| The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins. | Q33257520 | ||
| A role for PCNA ubiquitination in immunoglobulin hypermutation | Q33263578 | ||
| Mismatch repair and immunoglobulin gene hypermutation: did we learn something? | Q33756019 | ||
| Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification | Q33853914 | ||
| Light chain gene conversion continues at high rate in an ALV-induced cell line. | Q33918728 | ||
| Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. | Q33945446 | ||
| Quantitative measurement of translesion replication in human cells: evidence for bypass of abasic sites by a replicative DNA polymerase | Q34020161 | ||
| Eukaryotic DNA polymerases: proposal for a revised nomenclature. | Q34093113 | ||
| Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene. | Q34098247 | ||
| Error-prone repair DNA polymerases in prokaryotes and eukaryotes | Q34131455 | ||
| Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota. | Q34157224 | ||
| The expanding polymerase universe | Q34186298 | ||
| Mammalian DNA beta-polymerase in base excision repair of alkylation damage. | Q34367301 | ||
| Induction of somatic mutation in a human B cell line in vitro | Q34418234 | ||
| DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse | Q34595025 | ||
| Increased catalytic activity and altered fidelity of human DNA polymerase iota in the presence of manganese | Q34645605 | ||
| Specialized DNA polymerases, cellular survival, and the genesis of mutations | Q34662609 | ||
| V(D)J recombination: RAG proteins, repair factors, and regulation | Q34667417 | ||
| Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease | Q34719398 | ||
| AID and mismatch repair in antibody diversification | Q34770418 | ||
| What role for AID: mutator, or assembler of the immunoglobulin mutasome? | Q35164207 | ||
| Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias | Q35792957 | ||
| DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination | Q36229513 | ||
| A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification | Q36229591 | ||
| Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines | Q36238936 | ||
| The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation. | Q36248087 | ||
| Suffering in silence: the tolerance of DNA damage | Q36337954 | ||
| DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination. | Q36399002 | ||
| Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions | Q36399387 | ||
| Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse | Q36403507 | ||
| A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination | Q36403922 | ||
| Somatic hypermutation: subverted DNA repair | Q36449996 | ||
| Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region | Q36630020 | ||
| Cernunnos-XLF, a recently identified non-homologous end-joining factor required for the development of the immune system. | Q36646663 | ||
| Ongoing diversification of the rearranged immunoglobulin light-chain gene in a bursal lymphoma cell line | Q36712061 | ||
| Molecular mechanisms of antibody somatic hypermutation. | Q36747477 | ||
| A biochemically defined system for mammalian nonhomologous DNA end joining | Q38333666 | ||
| Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line. | Q39744882 | ||
| Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota. | Q40323781 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 302-312 | |
| P577 | publication date | 2008-03-14 | |
| P1433 | published in | Nature Reviews Immunology | Q43355 |
| P1476 | title | DNA polymerases in adaptive immunity | |
| P478 | volume | 8 |
| Q27655731 | 3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases |
| Q91666298 | A practical guide for mutational signature analysis in hematological malignancies |
| Q34118000 | AID and somatic hypermutation. |
| Q36443102 | AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma. |
| Q37815430 | AID: a riddle wrapped in a mystery inside an enigma |
| Q37326085 | Competitive repair pathways in immunoglobulin gene hypermutation. |
| Q90057553 | Current insights into the mechanism of mammalian immunoglobulin class switch recombination |
| Q37197911 | DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes |
| Q41909494 | DNA polymerases at the replication fork in eukaryotes |
| Q42937091 | Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation. |
| Q28241953 | Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation |
| Q42085226 | Differential regulation of full-length genome and a single-stranded 7S DNA along the cell cycle in human mitochondria |
| Q36173864 | Does DNA repair occur during somatic hypermutation? |
| Q34270452 | Epstein-Barr virus infection of naïve B cells in vitro frequently selects clones with mutated immunoglobulin genotypes: implications for virus biology. |
| Q34222332 | Error-Prone DNA Repair Activity during Somatic Hypermutation in Shark B Lymphocytes |
| Q33703002 | Fanca deficiency reduces A/T transitions in somatic hypermutation and alters class switch recombination junctions in mouse B cells. |
| Q46553266 | Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells. |
| Q93012447 | Large deletions in immunoglobulin genes are associated with a sustained absence of DNA Polymerase η |
| Q24646190 | Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination |
| Q28537676 | Molecular evolution and diversity of Conus peptide toxins, as revealed by gene structure and intron sequence analyses |
| Q41984058 | Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs. |
| Q36699771 | Proteasomal degradation restricts the nuclear lifespan of AID |
| Q33496409 | Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress |
| Q33557562 | Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2. |
| Q90050600 | Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans |
| Q33820327 | Replicative Stress and the FHIT Gene: Roles in Tumor Suppression, Genome Stability and Prevention of Carcinogenesis |
| Q41999588 | Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination |
| Q28266265 | Role of non-homologous end joining in V(D)J recombination |
| Q52431678 | SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation. |
| Q24630493 | Separate roles of structured and unstructured regions of Y-family DNA polymerases |
| Q33743606 | Somatic hypermutation at A/T-rich oligonucleotide substrates shows different strand polarities in Ung-deficient or -proficient backgrounds. |
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