| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Loeb LA | |
| Jackson AL | |||
| P2860 | cites work | Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis | Q22122362 |
| Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death | Q24312211 | ||
| Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability | Q24319995 | ||
| Rates of spontaneous mutation among RNA viruses | Q24563020 | ||
| Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization | Q24564349 | ||
| The age distribution of cancer and a multi-stage theory of carcinogenesis | Q24564904 | ||
| A genetic model for colorectal tumorigenesis | Q27860582 | ||
| Mutation of a mutL homolog in hereditary colon cancer | Q28114939 | ||
| Mechanism of activation of the TGF-beta receptor | Q28245861 | ||
| Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer | Q28257360 | ||
| Genetic mapping of a locus predisposing to human colorectal cancer | Q28268634 | ||
| A constant rate of spontaneous mutation in DNA-based microbes | Q28271032 | ||
| The clonal evolution of tumor cell populations | Q28271546 | ||
| APC mutations occur early during colorectal tumorigenesis | Q28274764 | ||
| Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis | Q72050023 | ||
| Genomic instability of microsatellite repeats in prostate cancer: relationship to clinicopathological variables | Q72255961 | ||
| Frequent microsatellite alterations on chromosome 3p in esophageal squamous cell carcinoma | Q72532691 | ||
| Genetic instability of microsatellites in endometrial carcinoma | Q72559451 | ||
| Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons | Q72710428 | ||
| Loss of Apc+ in intestinal adenomas from Min mice | Q72789835 | ||
| Genetic alterations during colorectal-tumor development | Q28281200 | ||
| Inactivation of both APC alleles in human and mouse tumors | Q28587902 | ||
| Regulators of cell death | Q29042165 | ||
| The hypercycle. A principle of natural self-organization. Part A: Emergence of the hypercycle | Q29616074 | ||
| Rapid evolution of RNA genomes | Q29616272 | ||
| Microsatellite instability in cancer of the proximal colon | Q29620692 | ||
| Detection of a human CFC with a high proliferative potential. | Q30459910 | ||
| Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines | Q33720790 | ||
| Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs | Q34554581 | ||
| Mutator phenotypes in human colorectal carcinoma cell lines | Q35568305 | ||
| The rate with which spontaneous mutation alters the electrophoretic mobility of polypeptides | Q35586424 | ||
| Proliferation of mutators in A cell population | Q35618973 | ||
| The origin of point mutations in human tumor cells | Q36729577 | ||
| APC mutations in colorectal tumors with mismatch repair deficiency | Q37383704 | ||
| Errors in DNA replication as a basis of malignant changes | Q39870986 | ||
| Regulation of lymphocyte survival by the bcl-2 gene family | Q40444925 | ||
| The molecular basis of oncogenes and tumor suppressor genes. | Q40454392 | ||
| Microsatellite instability in inherited and sporadic neoplasms | Q40493550 | ||
| Instability of microsatellites in human gliomas. | Q40607686 | ||
| Microsatellite instability: marker of a mutator phenotype in cancer. | Q40630726 | ||
| Viral quasispecies. | Q40828271 | ||
| Life, death, and the pursuit of apoptosis. | Q40942974 | ||
| Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. | Q40962229 | ||
| Analysis of replication error (RER+) phenotypes in cervical carcinoma | Q41215581 | ||
| Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer | Q41332396 | ||
| Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation | Q41448577 | ||
| Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability | Q41467421 | ||
| APC mutation associated with late onset of familial adenomatous polyposis | Q41662035 | ||
| Transient mutators: a semiquantitative analysis of the influence of translation and transcription errors on mutation rates | Q41999710 | ||
| Estimation of mutation rates based on the analysis of polypeptide constituents of cultured human lymphoblastoid cells | Q42053098 | ||
| The analysis of malignancy by cell fusion: the position in 1988. | Q44577345 | ||
| Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer | Q45345220 | ||
| Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation | Q46049171 | ||
| Genetic analysis of benign, low-grade, and high-grade ovarian tumors | Q46325670 | ||
| Somatic microsatellite mutations as molecular tumor clocks | Q46820533 | ||
| Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer | Q48084125 | ||
| Molecular determinants of dysplasia in colorectal lesions. | Q52512023 | ||
| A statistical model to estimate variance in long term-low dose mutation assays: testing of the model in a human lymphoblastoid mutation assay. | Q52531215 | ||
| Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. | Q53445992 | ||
| Role of mutator alleles in adaptive evolution. | Q54564129 | ||
| The spontaneous azaguanine-resistant mutants of diploid human fibroblasts. | Q54662446 | ||
| Microsatellite instability at multiple loci in gastric carcinoma: Clinicopathologic implications and prognosis | Q61627303 | ||
| Karyotypic evolution in human malignant melanoma | Q69988265 | ||
| Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP) | Q70472511 | ||
| Molecular detection of primary bladder cancer by microsatellite analysis | Q70923967 | ||
| Frequent co-occurrence of mutator phenotype in synchronous, independent multiple cancers of the stomach | Q71006274 | ||
| Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis | Q71102439 | ||
| Mismatch repair, somatic mutations, and the origins of cancer | Q71805147 | ||
| Microsatellite instability in aberrant crypt foci from human colons | Q71900049 | ||
| A transforming growth factor beta type II receptor gene mutation common in sporadic cecum cancer with microsatellite instability | Q71909523 | ||
| A hereditary genetic marker closely associated with microsatellite instability in lung cancer | Q72033731 | ||
| P433 | issue | 4 | |
| P1104 | number of pages | 8 | |
| P304 | page(s) | 1483-1490 | |
| P577 | publication date | 1998-04-01 | |
| P1433 | published in | Genetics | Q3100575 |
| P1476 | title | The mutation rate and cancer | |
| P478 | volume | 148 |
| Q24794741 | 5-halogenated pyrimidine lesions within a CpG sequence context mimic 5-methylcytosine by enhancing the binding of the methyl-CpG-binding domain of methyl-CpG-binding protein 2 (MeCP2). |
| Q50318144 | A Simple 3-Parameter Model for Cancer Incidences |
| Q35372337 | A new model of time scheme for progression of colorectal cancer |
| Q56898183 | Accuracy of Next Generation Sequencing Platforms |
| Q24623723 | Adaptive mutation: implications for evolution |
| Q34386480 | An association, in adult Japanese, between the occurrence of rogue cells among cultured lymphocytes (JC virus activity) and the frequency of "simple" chromosomal damage among the lymphocytes of persons exhibiting these rogue cells |
| Q90728321 | Association of Uveal Melanoma Metastatic Rate With Stochastic Mutation Rate and Type of Mutation |
| Q26779417 | Can Peto's paradox be used as the null hypothesis to identify the role of evolution in natural resistance to cancer? A critical review |
| Q37295279 | Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group |
| Q33943859 | Clusters of mutations from transient hypermutability |
| Q36582348 | Commentary: nm23, a metastasis suppressor gene with a tumor suppressor gene aptitude? |
| Q55333033 | Competition and niche construction in a model of cancer metastasis. |
| Q64387724 | Cooperation between non-essential DNA polymerases contributes to genome stability in Saccharomyces cerevisiae |
| Q36854134 | CpG island methylation in familial colorectal cancer patients not fulfilling the Amsterdam criteria |
| Q36754647 | DNA damage regulation and its role in drug-related phenotypes in the malaria parasites |
| Q33991388 | Direct selection for mutators in Escherichia coli. |
| Q39645960 | Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant |
| Q34662452 | Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations. |
| Q36224261 | Expression of p14(ARF), p15(INK4b), p16(INK4a) and skp2 increases during esophageal squamous cell cancer progression |
| Q37351268 | Functional study of the P32T ITPA variant associated with drug sensitivity in humans. |
| Q36605539 | Genetic damage in patients with chronic kidney disease, peritoneal dialysis and haemodialysis: a comparative study. |
| Q42726260 | Genetic instability and the mutator phenotype. Studies in ulcerative colitis |
| Q40442613 | Genomic instability in radial growth phase melanoma cell lines after ultraviolet irradiation |
| Q24563115 | HER-2 gene amplification can be acquired as breast cancer progresses |
| Q34055705 | Human base excision repair creates a bias toward -1 frameshift mutations |
| Q33716224 | Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde |
| Q93066256 | In vivo maturation of human embryonic stem cell-derived teratoma over time |
| Q41576528 | Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development |
| Q35550260 | Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans |
| Q21563511 | Modeling somatic evolution in tumorigenesis |
| Q33849634 | Modeling variation in tumors in vivo |
| Q37483304 | Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools |
| Q37197308 | Molecular identification of "latent precancers" for endometrial serous carcinoma in benign-appearing endometrium |
| Q36031579 | Mutational heterogeneity in human cancers: origin and consequences. |
| Q55060101 | Mutational signatures and mutable motifs in cancer genomes. |
| Q36417805 | Mutational targets in colorectal cancer cells with microsatellite instability. |
| Q35063954 | Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene. |
| Q34607018 | Mutators, population size, adaptive landscape and the adaptation of asexual populations of bacteria |
| Q34926078 | Only three driver gene mutations are required for the development of lung and colorectal cancers |
| Q42434669 | Our contribution to the public fear of cancer |
| Q34390268 | PIG-A mutations in normal hematopoiesis |
| Q43250252 | Pathways to tumorigenesis--modeling mutation acquisition in stem cells and their progeny |
| Q41682086 | Preliminary evidence of different selection pressures on cancer cells as compared to normal tissues |
| Q38793244 | Progression inference for somatic mutations in cancer |
| Q35203134 | Protein domain-level landscape of cancer-type-specific somatic mutations |
| Q91968752 | Proteogenomic Analysis of Protein Sequence Alterations in Breast Cancer Cells |
| Q56902268 | Recombination and its roles in DNA repair, cellular immortalization and cancer |
| Q36950684 | Regression of latent endometrial precancers by progestin infiltrated intrauterine device |
| Q36540486 | Regulation of mismatch repair by histone code and posttranslational modifications in eukaryotic cells |
| Q37375397 | Road to the crossroads of life and death: linking sister chromatid cohesion and separation to aneuploidy, apoptosis and cancer |
| Q54597642 | Stochastic dynamics of leukemic cells under an intermittent targeted therapy. |
| Q42426795 | Stochastic tunnels in evolutionary dynamics |
| Q51052567 | Stress-induced mutagenesis and complex adaptation. |
| Q38768283 | The Damaging Effect of Passenger Mutations on Cancer Progression |
| Q28742524 | The genome as a life-history character: why rate of molecular evolution varies between mammal species |
| Q33807763 | The inflammatory network: bridging senescent stroma and epithelial tumorigenesis |
| Q24541508 | The role of chromosomal instability in tumor initiation |
| Q35609296 | Tumbling down a different pathway to genetic instability. |
| Q35752935 | Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin |
| Q46904792 | Turning ecology and evolution against cancer |
| Q28544655 | Within-host stochastic emergence dynamics of immune-escape mutants |
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