Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system.

scientific article published on 30 March 2009

Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.00428-08
P932PMC publication ID2687204
P698PubMed publication ID19332676

P50authorNiels HøibyQ12328808
Henrik Enghusen PoulsenQ33310622
Oana CiofuQ40705960
Lasse Engbo ChristiansenQ42754296
P2093author name stringN Kirkby
L F Mandsberg
P2860cites workComplete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogenQ22122393
Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrateQ24564458
State of the Art: Why do the lungs of patients with cystic fibrosis become infected and why can't they clear the infection?Q24802489
Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1Q28190916
Evolution of mutation rates in bacteriaQ28238561
The mismatch repair system (mutS, mutL and uvrD genes) in Pseudomonas aeruginosa: molecular characterization of naturally occurring mutantsQ28492576
Characterization of the GO system of Pseudomonas aeruginosaQ28492940
Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas aeruginosaQ28493072
Construction of improved Escherichia-Pseudomonas shuttle vectors derived from pUC18/19 and sequence of the region required for their replication in Pseudomonas aeruginosaQ29615291
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)Q29619959
High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.Q34508854
New antimicrobials in the management of cystic fibrosisQ34508869
Antimutator role of the DNA glycosylase mutY gene in Helicobacter pyloriQ35075343
The mutant selection window and antimicrobial resistanceQ35153856
The role of mutators in the emergence of antibiotic-resistant bacteriaQ35177659
Role of a MutY DNA glycosylase in combating oxidative DNA damage in Helicobacter pyloriQ35691709
Establishment of aging biofilms: possible mechanism of bacterial resistance to antimicrobial therapyQ35754096
Influence of high mutation rates on the mechanisms and dynamics of in vitro and in vivo resistance development to single or combined antipseudomonal agents.Q35879111
Understanding bacterial biofilms in patients with cystic fibrosis: current and innovative approaches to potential therapiesQ35908307
Survival strategies of infectious biofilmsQ36003660
Resistance mechanisms of multiresistant Pseudomonas aeruginosa strains from Germany and correlation with hypermutationQ36295397
Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolatesQ37007127
Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNAQ37132610
Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in gram-negative bacteriaQ37608709
Weak mutators can drive the evolution of fluoroquinolone resistance in Escherichia coliQ38665569
Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patientsQ39473195
Molecular mechanisms of beta-lactam resistance mediated by AmpC hyperproduction in Pseudomonas aeruginosa clinical strains.Q39609617
Different spectra of stationary-phase mutations in early-arising versus late-arising mutants of Pseudomonas putida: involvement of the DNA repair enzyme MutY and the stationary-phase sigma factor RpoS.Q39680847
Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosaQ39781815
Detection and susceptibility testing of hypermutable Pseudomonas aeruginosa strains with the Etest and disk diffusionQ40968218
Occurrence of hypermutable Pseudomonas aeruginosa in cystic fibrosis patients is associated with the oxidative stress caused by chronic lung inflammationQ41825397
Hypermutation is a key factor in development of multiple-antimicrobial resistance in Pseudomonas aeruginosa strains causing chronic lung infectionsQ41974061
Pulmonary oxidative stress response in young children with cystic fibrosisQ42152011
Oxidative DNA damage defense systems in avoidance of stationary-phase mutagenesis in Pseudomonas putidaQ42412527
Rapid development in vitro and in vivo of resistance to ceftazidime in biofilm-growing Pseudomonas aeruginosa due to chromosomal beta-lactamaseQ42496962
Pseudomonas aeruginosa-induced lung injury: role of oxidative stressQ43848320
Response of Escherichia coli hypermutators to selection pressure with antimicrobial agents from different classes.Q44012036
Interactions among the Escherichia coli mutT, mutM, and mutY damage prevention pathwaysQ44280600
Lipid peroxidation of lung surfactant due to reactive oxygen species released from phagocytes stimulated by bacteria from children with cystic fibrosisQ44689347
Characterization of starvation-induced dispersion in Pseudomonas putida biofilmsQ46489224
Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repairQ46617407
Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.Q47946251
High mutation frequencies among Escherichia coli and Salmonella pathogensQ48057867
An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosaQ48073553
Molecular analysis of mutS expression and mutation in natural isolates of pathogenic Escherichia coliQ48248666
Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia coliQ49201462
Effects of overexpression and antisense RNA expression of Orf17, a MutT-type enzyme.Q54464045
Role of mutator alleles in adaptive evolution.Q54564129
Costs and Benefits of High Mutation Rates: Adaptive Evolution of Bacteria in the Mouse GutQ56944626
Highly Variable Mutation Rates in Commensal and Pathogenic Escherichia coliQ56944671
Suppression of spontaneous and hydrogen peroxide-induced mutations by a MutT-type nucleotide pool sanitization enzyme, the Escherichia coli Orf135 proteinQ57751251
Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosisQ61477562
Evidence for increased oxidative damage in patients with cystic fibrosisQ72397235
Aminoglycoside-resistance mechanisms for cystic fibrosis Pseudomonas aeruginosa isolates are unchanged by long-term, intermittent, inhaled tobramycin treatmentQ73556642
Hypermutation as a Factor Contributing to the Acquisition of Antimicrobial ResistanceQ79162727
Hypermutability in environmental Pseudomonas aeruginosa and in populations causing pulmonary infection in individuals with cystic fibrosisQ80385327
Oxidative changes of bronchoalveolar proteins in cystic fibrosisQ82554110
Sequence variability and functional analysis of MutS of hypermutable Pseudomonas aeruginosa cystic fibrosis isolatesQ82856564
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectPseudomonas aeruginosaQ31856
antibiotic resistanceQ380775
P1104number of pages9
P304page(s)2483-2491
P577publication date2009-03-30
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleAntibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system
P478volume53

Reverse relations

cites work (P2860)
Q33576726A MATE-family efflux pump rescues the Escherichia coli 8-oxoguanine-repair-deficient mutator phenotype and protects against H(2)O(2) killing
Q35230652Antimicrobial resistance in the respiratory microbiota of people with cystic fibrosis
Q37794342Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance
Q30403958Biofilm-related infections: bridging the gap between clinical management and fundamental aspects of recalcitrance toward antibiotics.
Q90380584Contribution of GO System Glycosylases to Mutation Prevention in Caulobacter crescentus
Q41833848Effect of ciprofloxacin concentration on the frequency and nature of resistant mutants selected from Pseudomonas aeruginosa mutS and mutT hypermutators
Q24609407Efflux-mediated drug resistance in bacteria: an update
Q37896674Emergence and spread of antibiotic resistance following exposure to antibiotics
Q38211644Evolution and impact of bacterial drug resistance in the context of cystic fibrosis disease and nosocomial settings
Q36559344Evolution in fast forward: a potential role for mutators in accelerating Staphylococcus aureus pathoadaptation
Q28359832Evolutionary diversification of Pseudomonas aeruginosa in an artificial sputum model
Q38962871Involvement of stress-related genes polB and PA14_46880 in biofilm formation of Pseudomonas aeruginosa
Q51173006Microbial ecology and adaptation in cystic fibrosis airways.
Q34117477Mucoidy, quorum sensing, mismatch repair and antibiotic resistance in Pseudomonas aeruginosa from cystic fibrosis chronic airways infections
Q37888731New horizons for cutaneous microbiology: the role of biofilms in dermatological disease
Q38006032Phenotypes selected during chronic lung infection in cystic fibrosis patients: implications for the treatment of Pseudomonas aeruginosa biofilm infections
Q38645992Phenotypic and genetic heterogeneity within biofilms with particular emphasis on persistence and antimicrobial tolerance.
Q46597577Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in guinea pigs.
Q42734622Preparation and physicochemical characterization of amoxicillin beta-cyclodextrin complexes
Q40058358Production of highly stable spray dried phage formulations for treatment of Pseudomonas aeruginosa lung infection.
Q38268531Pseudomonas aeruginosa biofilm infections: from molecular biofilm biology to new treatment possibilities.
Q28299966Pseudomonas aeruginosa biofilms in cystic fibrosis
Q35084559Pseudomonas aeruginosa: resistance to the max
Q33559774Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients
Q37464130Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels
Q42572942Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa
Q40293607Surface charge modification decreases Pseudomonas aeruginosa adherence in vitro and bacterial persistence in an in vivo implant model
Q35482558The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria
Q28492495The glycerol-3-phosphate permease GlpT is the only fosfomycin transporter in Pseudomonas aeruginosa
Q38300820The problems of antibiotic resistance in cystic fibrosis and solutions
Q35885995The properties of spontaneous mutations in the opportunistic pathogen Pseudomonas aeruginosa
Q36469527The role of 2,4-dihydroxyquinoline (DHQ) in Pseudomonas aeruginosa pathogenicity

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