A MATE-family efflux pump rescues the Escherichia coli 8-oxoguanine-repair-deficient mutator phenotype and protects against H(2)O(2) killing

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A MATE-family efflux pump rescues the Escherichia coli 8-oxoguanine-repair-deficient mutator phenotype and protects against H(2)O(2) killing is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1000931
P932PMC publication ID2865507
P698PubMed publication ID20463878
P5875ResearchGate publication ID44593415

P50authorJesus BlazquezQ68273789
P2093author name stringAlexandro Rodríguez-Rojas
Ivan Matic
Javier R Guelfo
P2860cites workConstruction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collectionQ22122301
NorM, a putative multidrug efflux protein, of Vibrio parahaemolyticus and its homolog in Escherichia coliQ24519031
A human transporter protein that mediates the final excretion step for toxic organic cationsQ24534261
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
The multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamilyQ27930875
Molecular properties of bacterial multidrug transportersQ28139376
The multidrug efflux protein NorM is a prototype of a new family of transportersQ28297090
Mismatch repair in replication fidelity, genetic recombination, and cancer biologyQ29616483
Estimate of the genomic mutation rate deleterious to overall fitness in E. coli.Q51030744
Spontaneous mutagenesis is elevated in protease-defective cells.Q54413180
In vivo DNA cloning with a mini-Mu replicon cosmid and a helper lambda phage.Q54417364
Incidence of mutator strains in Escherichia coli and coliforms in nature.Q54538245
Suppressors of Escherichia coli mutT: antimutators for DNA replication errors.Q54593529
Regulation of the regulatory gene for the arabinose pathway, araCQ56659694
Highly Variable Mutation Rates in Commensal and Pathogenic Escherichia coliQ56944671
Rapid repeated cloning of mutant lac repressor genesQ57192132
Formation of 8-oxoguanine in cellular DNA of Escherichia coli strains defective in different antioxidant defencesQ58448110
The evolution of mutation ratesQ69536377
COMPETITION BETWEEN HIGH AND LOW MUTATING STRAINS OF ESCHERICHIA COLIQ88206326
Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological researchQ29619122
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)Q29619959
Identification of mutator genes and mutational pathways in Escherichia coli using a multicopy cloning approachQ31085131
Muller's ratchet decreases fitness of a DNA-based microbeQ33588611
A novel role for Escherichia coli endonuclease VIII in prevention of spontaneous G-->T transversions.Q33638108
The population genetics of ecological specialization in evolving Escherichia coli populationsQ33922714
A set of lacZ mutations in Escherichia coli that allow rapid detection of specific frameshift mutationsQ33956589
Mutants of Escherichia coli with increased fidelity of DNA replicationQ33961314
The mutational specificity of two Escherichia coli dnaE antimutator alleles as determined from lacI mutation spectraQ33961321
Selection for high mutation rates in chemostatsQ33989687
The rise and fall of mutator bacteria.Q34392588
High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.Q34508854
The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitnessQ34609052
Molecular basis of valine resistance in Escherichia coli K-12Q35419442
The frequency and structure of recombinant products is determined by the cellular level of MutL.Q35829125
Genetic effects of oxidative DNA damage: comparative mutagenesis of 7,8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine in Escherichia coliQ35935140
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Mutagenesis and stress responses induced in Escherichia coli by hydrogen peroxideQ36239906
In vivo DNA cloning and adjacent gene fusing with a mini-Mu-lac bacteriophage containing a plasmid repliconQ36251980
Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coliQ36870946
Stress-induced mutagenesis in bacteria.Q36961683
A MATE family multidrug efflux transporter pumps out fluoroquinolones in Bacteroides thetaiotaomicronQ39479055
Phylogenetic evidence for horizontal transfer of mutS alleles among naturally occurring Escherichia coli strainsQ39502754
The GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosaQ40324438
Selection against hypermutability in Escherichia coli during long term evolutionQ41568929
Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system.Q41937031
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutionsQ44480509
Fitness of an Escherichia coli Mutator GeneQ45158915
High mutation frequencies among Escherichia coli and Salmonella pathogensQ48057867
Genomic buffering mitigates the effects of deleterious mutations in bacteriaQ50085780
Evolutionary implications of the frequent horizontal transfer of mismatch repair genesQ50117948
A modified Luria-Delbrück fluctuation assay for estimating and comparing mutation ratesQ50138265
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P921main subjectEscherichia coliQ25419
P304page(s)e1000931
P577publication date2010-05-06
P1433published inPLOS GeneticsQ1893441
P1476titleA MATE-family efflux pump rescues the Escherichia coli 8-oxoguanine-repair-deficient mutator phenotype and protects against H(2)O(2) killing
P478volume6

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cites work (P2860)
Q46473085A novel regulatory circuit to control indole biosynthesis protects Escherichia coli from nitrosative damages during the anaerobic respiration of nitrate.
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Q35582418EmmdR, a new member of the MATE family of multidrug transporters, extrudes quinolones from Enterobacter cloacae
Q35599902Escherichia coli populations in unpredictably fluctuating environments evolve to face novel stresses through enhanced efflux activity
Q41887110Functional analysis of pneumococcal drug efflux pumps associates the MATE DinF transporter with quinolone susceptibility
Q37839122Molecular targets of oxidative stress.
Q38572833More Than Just Light: Clinical Relevance of Light Perception in the Nosocomial Pathogen Acinetobacter baumannii and Other Members of the Genus Acinetobacter
Q34998550Normal mutation rate variants arise in a Mutator (Mut S) Escherichia coli population.
Q41811490Oxidative DNA damage is instrumental in hyperreplication stress-induced inviability of Escherichia coli.
Q34263142Principles of carbon catabolite repression in the rice blast fungus: Tps1, Nmr1-3, and a MATE-family pump regulate glucose metabolism during infection
Q28482375The Escherichia coli SOS gene dinF protects against oxidative stress and bile salts
Q35482558The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria

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