An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy

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An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/EVO.13041
P8608Fatcat IDrelease_qjavlaofbbcw5n4gnnqhsof6wa
P698PubMed publication ID27566611

P50authorMatthieu FollQ30114358
Jeffrey D. JensenQ40513972
Claudia BankQ57548171
Hyunjin ShimQ57951020
P2093author name stringJennifer P Wang
Konstantin B Zeldovich
Nicholas Renzette
Ping Liu
Robert W Finberg
Timothy F Kowalik
Daniel N A Bolon
Sebastian Matuszewski
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Influenza A virus polymerase is a site for adaptive changes during experimental evolution in bat cellsQ28650894
Mortality associated with influenza and respiratory syncytial virus in the United StatesQ29615578
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Mutation induced extinction in finite populations: lethal mutagenesis and lethal isolationQ34372268
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A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelityQ35163547
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An overlapping protein-coding region in influenza A virus segment 3 modulates the host responseQ36554219
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Thinking too positive? Revisiting current methods of population genetic selection inferenceQ38273399
Evolution of the influenza A virus genome during development of oseltamivir resistance in vitroQ39071692
The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo.Q40579225
Prevention and treatment of bronchopneumonia in mice caused by mouse-adapted variant of avian H5N2 influenza A virus using monoclonal antibody against conserved epitope in the HA stem regionQ40852854
Lethal mutagenesis and evolutionary epidemiologyQ40863246
The mutational meltdown in asexual populationsQ41067565
Mechanism of action of T-705 against influenza virusQ41091905
Favipiravir elicits antiviral mutagenesis during virus replication in vivoQ41693281
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P433issue11
P1104number of pages15
P304page(s)2470-2484
P577publication date2016-08-26
P1433published inEvolutionQ4038411
P1476titleAn experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy.
P478volume70

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cites work (P2860)
Q91595542Considering mutational meltdown as a potential SARS-CoV-2 treatment strategy
Q91930483Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy
Q47130579Experimental adaptation of human echovirus 11 to ultraviolet radiation leads to resistance to disinfection and ribavirin
Q63976719Influenza virus polymerase inhibitors in clinical development
Q58089563Mutations in influenza A virus neuraminidase and hemagglutinin confer resistance against a broadly neutralizing hemagglutinin stem antibody
Q40072274Resistance of Echovirus 11 to ClO2 Is Associated with Enhanced Host Receptor Use, Altered Entry Routes, and High Fitness
Q40064817The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution.
Q57799444The mechanism of resistance to favipiravir in influenza
Q55424984Two sides of the same coin: A population genetics perspective on lethal mutagenesis and mutational meltdown.

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