Thioridazine as Chemotherapy for Mycobacterium avium Complex Diseases

scientific article published on 23 May 2016

Thioridazine as Chemotherapy for Mycobacterium avium Complex Diseases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.02985-15
P932PMC publication ID4958214
P698PubMed publication ID27216055

P50authorSandirai MusukaQ117260819
Tawanda GumboQ40336008
Shashikant SrivastavaQ56381433
Devyani DeshpandeQ58917103
P2860cites workDiagnosis and Treatment of Disease Caused by Nontuberculous MycobacteriaQ22241907
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The role of lysosomes in the cellular distribution of thioridazine and potential drug interactionsQ33178661
Reduced emergence of isoniazid resistance with concurrent use of thioridazine against acute murine tuberculosis.Q33798280
Intrapulmonary pharmacokinetics and pharmacodynamics of micafungin in adult lung transplant patientsQ34045450
Evolution in changing environments: modifiers of mutation, recombination, and migrationQ34752908
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An evolutionary reduction principle for genetic modifiersQ35614856
The antibiotic resistance arrow of time: efflux pump induction is a general first step in the evolution of mycobacterial drug resistanceQ36172383
Distribution of mycobacterial antigen based on differences of histological characteristics in pulmonary Mycobacterium avium infectious diseases--consideration of the extent of surgical resection from the pathological standpointQ83003982
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Interpretation of antibiotic concentration ratios measured in epithelial lining fluidQ36936597
Significance of Serum Protein and Tissue Binding of Antimicrobial AgentsQ37034927
Thioridazine pharmacokinetic-pharmacodynamic parameters "Wobble" during treatment of tuberculosis: a theoretical basis for shorter-duration curative monotherapy with congenersQ37335803
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The broad-spectrum antimycobacterial activities of phenothiazines, InVitro: somewhere in all of this there may be patentable potentialsQ37868591
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Protein binding: do we ever learn?Q37871252
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Forecasting Accuracy of the Hollow Fiber Model of Tuberculosis for Clinical Therapeutic OutcomesQ38979626
The role of efflux pumps in macrolide resistance in Mycobacterium avium complexQ39404012
Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatisQ39404019
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The in vitro activity of phenothiazines against Mycobacterium avium: potential of thioridazine for therapy of the co-infected AIDS patient.Q39563382
Moxifloxacin pharmacokinetics/pharmacodynamics and optimal dose and susceptibility breakpoint identification for treatment of disseminated Mycobacterium avium infectionQ39715580
Ethambutol optimal clinical dose and susceptibility breakpoint identification by use of a novel pharmacokinetic-pharmacodynamic model of disseminated intracellular Mycobacterium aviumQ40335980
Phenothiazines suppress proliferation and induce apoptosis in cultured leukemic cells without any influence on the viability of normal lymphocytes. Phenothiazines and leukemiaQ40609169
Correlations Between the Hollow Fiber Model of Tuberculosis and Therapeutic Events in Tuberculosis Patients: Learn and ConfirmQ40679730
Systematic Analysis of Hollow Fiber Model of Tuberculosis ExperimentsQ41082086
Interactions of chlorpromazine and imipramine with artificial membranes investigated by equilibrium dialysis, dual-wavelength photometry, and fluorimetryQ41668368
Role of Lysosomes in Hepatic Accumulation of ChloroquineQ41912287
Thioridazine cardiotoxicityQ42556427
Evolutionarily stable mutation rate in a periodically changing environment.Q42960953
Comparative distribution of azithromycin in lung tissue of patients given oral daily doses of 500 and 1000 mg.Q44374404
Changes in lipid structure produced by surfactant proteins SP-A, SP-B, and SP-C.Q45156342
Binding of basic and acidic drugs to rat tissue subcellular fractionsQ47877466
Distribution of thioridazine and its metabolites in human tissues and fluids obtained postmortem.Q48156900
Membrane lipids as intracellular binders of chlorpromazine and related drugsQ48308513
Role of mutator alleles in adaptive evolution.Q54564129
Predictors of survival in patients with AIDS and disseminated Mycobacterium avium complex diseaseQ58321694
Plasma levels and half lives of thioridazine and some of its metabolites. II. Low doses in older psychiatric patientsQ67549282
Modifiers of mutation rate: a general reduction principleQ69602852
Cardiotoxicity of thioridazine and two stereoisomeric forms of thioridazine 5-sulfoxide in the isolated perfused rat heartQ69630201
Tissue distribution of chlorpromazine studied by microautoradiographyQ71478019
Correlation of quantitative bone marrow and blood cultures in AIDS patients with disseminated Mycobacterium avium complex infectionQ77967992
Clinical, biochemical and post mortem studies on a patient treated with chlorpromazineQ79542790
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectMycobacterium avium aviumQ310728
chemotherapyQ974135
P304page(s)4652-4658
P577publication date2016-05-23
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleThioridazine as Chemotherapy for Mycobacterium avium Complex Diseases
P478volume60

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cites work (P2860)
Q41996877A 'shock and awe' thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium-intracellulare complex disease
Q41996885A novel ceftazidime/avibactam, rifabutin, tedizolid and moxifloxacin (CARTM) regimen for pulmonary Mycobacterium avium disease
Q41996871A programme to create short-course chemotherapy for pulmonary Mycobacterium avium disease based on pharmacokinetics/pharmacodynamics and mathematical forecasting
Q88909426Clofazimine for the Treatment of Mycobacterium kansasii
Q90781984Effect of efflux pump inhibitors on the susceptibility of Mycobacterium avium complex to clarithromycin
Q41996903Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance
Q41996896Linezolid as treatment for pulmonary Mycobacterium avium disease
Q92704112Looking beyond Typical Treatments for Atypical Mycobacteria
Q55340853Mycobacterial Response to Organic Solvents and Possible Implications on Cross-Resistance With Antimicrobial Agents.
Q41996895Tedizolid is highly bactericidal in the treatment of pulmonary Mycobacterium avium complex disease
Q41996889The discovery of ceftazidime/avibactam as an anti-Mycobacterium avium agent
Q42650868Treatment with high-dose antidepressants severely exacerbates the pathological outcome of experimental Escherichia coli infections in poultry.

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