Fidelity Variants and RNA Quasispecies.

scientific article

Fidelity Variants and RNA Quasispecies. is …
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scholarly articleQ13442814

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P356DOI10.1007/82_2015_483
P698PubMed publication ID26499340

P50authorAntonio V BorderíaQ37836622
Marco VignuzziQ39190581
P2093author name stringKathryn Rozen-Gagnon
P2860cites workPoliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub)Q73462886
Increased polymerase fidelity of lamivudine-resistant HIV-1 variants does not limit their evolutionary potentialQ78131151
Observations on two types of genetic instability in Escherichia coliQ78790920
Rates of spontaneous mutationQ24548000
Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High SpecificityQ24563898
Arbovirus high fidelity variant loses fitness in mosquitoes and miceQ24635860
Mutation rates among RNA virusesQ24643023
The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerasesQ24646382
Increased fidelity reduces poliovirus fitness and virulence under selective pressure in miceQ24817069
Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom ResolutionQ27480349
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virusQ27486092
Structure-function relationships among RNA-dependent RNA polymerasesQ27486391
Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active siteQ27619818
A mechanism for initiating RNA-dependent RNA polymerizationQ27630442
Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymeraseQ27635562
RNA synthesis in a cage--structural studies of reovirus polymerase lambda3Q27640090
Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiationQ27640501
Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleftQ27643088
The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymeraseQ27643134
Crystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA PolymeraseQ27643650
Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5Q27643756
The structure of a birnavirus polymerase reveals a distinct active site topologyQ27644594
Sequential structures provide insights into the fidelity of RNA replicationQ27644844
Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virusQ27651109
Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to RibavirinQ27660539
A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-EscapeQ27664656
Structural basis for active site closure by the poliovirus RNA-dependent RNA polymeraseQ27666339
Crystal Structure of Enterovirus 71 RNA-Dependent RNA Polymerase Complexed with Its Protein Primer VPg: Implication for a trans Mechanism of VPg UridylylationQ27676806
Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interfaceQ27679697
The Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active SiteQ27682030
Structure of the RNA-dependent RNA polymerase of poliovirusQ27744366
Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and BQ28145203
Selforganization of matter and the evolution of biological macromoleculesQ28248277
Variation in RNA virus mutation rates across host cellsQ28539101
Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in MosquitoesQ28545853
Quasispecies diversity determines pathogenesis through cooperative interactions in a viral populationQ29616266
The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA virusesQ29617966
A mechanism for all polymerasesQ29618812
3'-Azido-3'-deoxythymidine (AZT) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency virus type 1.Q30453467
Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencingQ33576672
Attenuation of human enterovirus 71 high-replication-fidelity variants in AG129 miceQ33602804
Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compoundsQ33741951
The cost of replication fidelity in an RNA virusQ33900476
Mutator activity of petite strains of Saccharomyces cerevisiaeQ33991421
Rationalizing the development of live attenuated virus vaccinesQ34119676
Generation and characterization of influenza A viruses with altered polymerase fidelityQ34137544
Evolution of high mutation rates in experimental populations of E. coliQ34429727
Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymeraseQ35012405
A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelityQ35163547
Isolation of fidelity variants of RNA viruses and characterization of virus mutation frequencyQ35391721
Reversion to neurovirulence of the live-attenuated Sabin type 3 oral pollovirus vaccineQ35448656
Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerasesQ35721277
Mutational robustness of an RNA virus influences sensitivity to lethal mutagenesisQ35826103
Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesisQ35907177
Quasispecies dynamics and RNA virus extinctionQ36008861
Coxsackievirus B3 mutator strains are attenuated in vivoQ36187182
Motif D of viral RNA-dependent RNA polymerases determines efficiency and fidelity of nucleotide additionQ36223299
Structure-function relationships of the viral RNA-dependent RNA polymerase: fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocketQ36225123
High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.Q36315521
A comparison of viral RNA-dependent RNA polymerasesQ36346703
A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal diseaseQ36456720
Ribavirin-resistant mutants of human enterovirus 71 express a high replication fidelity phenotype during growth in cell cultureQ36559853
Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selectionQ36718286
Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+.Q36718297
Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+.Q36718302
Vaccine-derived mutation in motif D of poliovirus RNA-dependent RNA polymerase lowers nucleotide incorporation fidelityQ37289325
The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiationQ37357669
DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studiesQ37442754
Alphavirus mutator variants present host-specific defects and attenuation in mammalian and insect modelsQ37488102
Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymeraseQ37513764
Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?Q37632038
Ribavirin-resistant variants of foot-and-mouth disease virus: the effect of restricted quasispecies diversity on viral virulenceQ37713899
Foot-and-mouth disease virus low-fidelity polymerase mutants are attenuatedQ38989187
Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastropheQ40199734
Heterogeneity of the mutation rates of influenza A viruses: isolation of mutator mutantsQ40308879
Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primerQ40727573
Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirinQ41360264
Long-Range Interaction Networks in the Function and Fidelity of Poliovirus RNA-Dependent RNA Polymerase Studied by Nuclear Magnetic ResonanceQ41673287
Interrelationship between HIV-1 fitness and mutation rate.Q41888126
Amiloride derivatives inhibit coxsackievirus B3 RNA replication.Q41914133
Structural and functional characterization of sapovirus RNA-dependent RNA polymeraseQ41975506
Nucleic acid polymerases use a general acid for nucleotidyl transferQ42239117
An increased replication fidelity mutant of foot-and-mouth disease virus retains fitness in vitro and virulence in vivoQ42253957
A study of the virulence in mice of high copying fidelity variants of human enterovirus 71.Q42255053
Studies on the biochemical basis of spontaneous mutation. I. A comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage T4.Q45061692
Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA.Q45152970
Control of mutation frequency by bacteriophage T4 DNA polymerase. I. The CB120 antimutator DNA polymerase is defective in strand displacementQ45275963
Engineering attenuated virus vaccines by controlling replication fidelityQ45397402
Mutational studies of human immunodeficiency virus type 1 reverse transcriptase: the involvement of residues 183 and 184 in the fidelity of DNA synthesisQ45768857
Generation of genetic diversity in herpes simplex virus: An antimutator phenotype maps to the DNA polymerase locusQ45797089
The crystal structure of the RNA-dependent RNA polymerase from human rhinovirus: a dual function target for common cold antiviral therapyQ46051411
High mutation frequencies among Escherichia coli and Salmonella pathogensQ48057867
Incidence of mutator strains in Escherichia coli and coliforms in nature.Q54538245
Role of mutator alleles in adaptive evolution.Q54564129
Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli.Q54648245
The cost of replication fidelity in human immunodeficiency virus type 1.Q55430533
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptaseQ71095982
Poliovirus RNA-dependent RNA polymerase (3D(pol)). Divalent cation modulation of primer, template, and nucleotide selectionQ73279890
P921main subjectviral quasispeciesQ3413375
P304page(s)303-322
P577publication date2016-01-01
P1433published inCurrent Topics in Microbiology and ImmunologyQ15752446
P1476titleFidelity Variants and RNA Quasispecies
P478volume392

Reverse relations

cites work (P2860)
Q423704761st Workshop of the Canadian Society for Virology
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Q48110822Quasispecies and virus.
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Q86320171Viral quasispecies

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