Mutators and hypermutability in bacteria: the Escherichia coli paradigm

scientific article published on December 2009

Mutators and hypermutability in bacteria: the Escherichia coli paradigm is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S12041-009-0058-2
P698PubMed publication ID20086310
P5875ResearchGate publication ID41088405

P2093author name stringJayaraman R
P2860cites workElevated expression of DNA polymerase II increases spontaneous mutagenesis in Escherichia coli.Q54439230
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Mycobacterium tuberculosis and Escherichia coli nucleoside diphosphate kinases lack multifunctional activities to process uracil containing DNAQ28487525
The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymesQ28573848
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The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)Q29619959
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Direct selection for mutators in Escherichia coli.Q33991388
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Amplification of mutator cells in a population as a result of horizontal transferQ33996324
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Escherichia coli strains (ndk) lacking nucleoside diphosphate kinase are powerful mutators for base substitutions and frameshifts in mismatch-repair-deficient strainsQ34615970
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Proofreading by DNA polymerase III of Escherichia coli depends on cooperative interaction of the polymerase and exonuclease subunitsQ34634040
Mutational analysis of the 3'-->5' proofreading exonuclease of Escherichia coli DNA polymerase IIIQ34674682
Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coliQ34697729
Coevolution with viruses drives the evolution of bacterial mutation rates.Q34722064
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Role of DNA polymerase IV in Escherichia coli SOS mutator activityQ35130259
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Escherichia coli K-12 clones that overproduce dam methylase are hypermutable.Q36323932
Replisome architecture and dynamics in Escherichia coliQ36371840
The multifaceted mismatch-repair systemQ36448284
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Mutator tRNAs are encoded by the Escherichia coli mutator genes mutA and mutC: a novel pathway for mutagenesisQ37637992
Mutants in the Exo I motif of Escherichia coli dnaQ: defective proofreading and inviability due to error catastropheQ37678547
Molecular and functional interactions between Escherichia coli nucleoside-diphosphate kinase and the uracil-DNA glycosylase Ung.Q38310794
Phylogenetic evidence for horizontal transfer of mutS alleles among naturally occurring Escherichia coli strainsQ39502754
Escherichia coli cells bearing a ribosomal ambiguity mutation in rpsD have a mutator phenotype that correlates with increased mistranslationQ39793949
Elevated mutation rate in mutT bacteria during starvation: evidence for DNA turnover?Q39841278
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The role of the mutT gene of Escherichia coli in maintaining replication fidelityQ41595474
Hypermutation is a key factor in development of multiple-antimicrobial resistance in Pseudomonas aeruginosa strains causing chronic lung infectionsQ41974061
Control of large chromosomal duplications in Escherichia coli by the mismatch repair systemQ42962535
DNA repair excision nuclease attacks undamaged DNA. A potential source of spontaneous mutationsQ43608425
Sequence analysis and phenotypes of five temperature sensitive mutator alleles of dnaE, encoding modified alpha-catalytic subunits of Escherichia coli DNA polymerase III holoenzyme.Q43862469
Interactions among the Escherichia coli mutT, mutM, and mutY damage prevention pathwaysQ44280600
Studies on the biochemical basis of spontaneous mutation. I. A comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage T4.Q45061692
Spontaneous mutagenesis associated with nucleotide excision repair in Escherichia coliQ45401435
Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repairQ46617407
Effect of deletion of SOS-induced polymerases, pol II, IV, and V, on spontaneous mutagenesis in Escherichia coli mutD5.Q47609306
The Contrasting Role of strA and ram Gene Products in Ribosomal FunctioningQ47777162
High mutation frequencies among Escherichia coli and Salmonella pathogensQ48057867
Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia coliQ49201462
P433issue3
P921main subjectEscherichia coliQ25419
P304page(s)379-391
P577publication date2009-12-01
P1433published inJournal of GeneticsQ975661
P1476titleMutators and hypermutability in bacteria: the Escherichia coli paradigm
P478volume88

Reverse relations

cites work (P2860)
Q49982300Distribution and Molecular Characterization of Salmonella enterica Hypermutators in Retail Food in China
Q95840911Genes and Proteomes Associated With Increased Mutation Frequency and Multidrug Resistance of Naturally Occurring Mismatch Repair-Deficient Salmonella Hypermutators
Q37922538Hypermutation and stress adaptation in bacteria
Q28247426Independent genome reduction and phylogenetic reclassification of the oceanic SAR11 clade
Q28069941Resistance mechanisms
Q42012937Role of DNA base excision repair in the mutability and virulence of Streptococcus mutans
Q54652456The evolution of bacterial mutation rates under simultaneous selection by interspecific and social parasitism.

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