Evolution and adaptation in Pseudomonas aeruginosa biofilms driven by mismatch repair system-deficient mutators.

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Evolution and adaptation in Pseudomonas aeruginosa biofilms driven by mismatch repair system-deficient mutators. is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...627842L
P356DOI10.1371/JOURNAL.PONE.0027842
P932PMC publication ID3219696
P698PubMed publication ID22114708
P5875ResearchGate publication ID51828095

P50authorSøren MolinQ26883279
Adela M LujánQ79447992
María D MaciáQ79793431
P2093author name stringLiang Yang
Antonio Oliver
Andrea M Smania
P2860cites worksigmaB regulates IS256-mediated Staphylococcus aureus biofilm phenotypic variationQ24680463
Multiple roles of biosurfactants in structural biofilm development by Pseudomonas aeruginosaQ24683834
The genomics and proteomics of biofilm formationQ24796049
DNA mismatch repair in eukaryotes and bacteriaQ28291067
Pseudomonas aeruginosa biofilms in cystic fibrosisQ28299966
Nucleotides and heteroduplex DNA preserve the active conformation of Pseudomonas aeruginosa MutS by preventing protein oligomerizationQ28366275
The mismatch repair system (mutS, mutL and uvrD genes) in Pseudomonas aeruginosa: molecular characterization of naturally occurring mutantsQ28492576
Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutantsQ28492790
Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilmsQ28493090
Quantification of biofilm structures by the novel computer program comstatQ28547921
Adaptive divergence in experimental populations of Pseudomonas fluorescens. I. Genetic and phenotypic bases of wrinkly spreader fitnessQ28768990
Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepaciaQ29615286
Biofilms as complex differentiated communitiesQ29615299
Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patientsQ29615301
Mismatch repair in replication fidelity, genetic recombination, and cancer biologyQ29616483
Development and dynamics of Pseudomonas sp. biofilmsQ30659180
Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutantsQ30944663
Simple sequence repeats and mucoid conversion: biased mucA mutagenesis in mismatch repair-deficient Pseudomonas aeruginosa.Q30974317
Dynamics of mutator and antibiotic-resistant populations in a pharmacokinetic/pharmacodynamic model of Pseudomonas aeruginosa biofilm treatment.Q31029779
Phenotypic diversification and adaptation of Serratia marcescens MG1 biofilm-derived morphotypesQ33261957
Physiological heterogeneity in biofilmsQ33319084
Role of mutation in Pseudomonas aeruginosa biofilm development.Q33482815
Spatial physiological heterogeneity in Pseudomonas aeruginosa biofilm is determined by oxygen availabilityQ33718373
Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.Q47946251
The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutantsQ50192890
Phenotypic differentiation and seeding dispersal in non-mucoid and mucoid Pseudomonas aeruginosa biofilms.Q51479991
Quorum-sensing-deficient (lasR) mutants emerge at high frequency from a Pseudomonas aeruginosa mutS strain.Q52575837
MutS deficiency and activity of the error-prone DNA polymerase IV are crucial for determining mucA as the main target for mucoid conversion in Pseudomonas aeruginosa.Q52579021
Role of mutator alleles in adaptive evolution.Q54564129
Adaptive radiation in a heterogeneous environmentQ56038387
Role of chronic Pseudomonas aeruginosa infection in the development of bronchiectasisQ67574773
Mucoid Pseudomonas aeruginosa is a marker of poor survival in cystic fibrosisQ68229087
Genetic recombination in Pseudomonas aeruginosaQ73881599
Chronic Pseudomonas aeruginosa infection in chronic obstructive pulmonary diseaseQ79805323
The effect of elevated mutation rates on the evolution of cooperation and virulence of Pseudomonas aeruginosaQ84417552
Molecular tools for study of biofilm physiologyQ33766161
Wider access to genotypic space facilitates loss of cooperation in a bacterial mutatorQ33833686
Amplification of mutator cells in a population as a result of horizontal transferQ33996324
Mucoidy, quorum sensing, mismatch repair and antibiotic resistance in Pseudomonas aeruginosa from cystic fibrosis chronic airways infectionsQ34117477
The rise and fall of mutator bacteria.Q34392588
Evolution of high mutation rates in experimental populations of E. coliQ34429727
High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.Q34508854
Stage-specific adaptation of hypermutable Pseudomonas aeruginosa isolates during chronic pulmonary infection in patients with cystic fibrosisQ34588476
Evolving stealth: genetic adaptation of Pseudomonas aeruginosa during cystic fibrosis infectionsQ34693974
Evolutionary dynamics of bacteria in a human host environmentQ34937408
Proliferation of mutators in A cell populationQ35618973
Characterization of colony morphology variants isolated from Streptococcus pneumoniae biofilmsQ35759418
Biofilm formation by the small colony variant phenotype of Pseudomonas aeruginosaQ35772673
Influence of high mutation rates on the mechanisms and dynamics of in vitro and in vivo resistance development to single or combined antipseudomonal agents.Q35879111
Characterization of a Pseudomonas putida rough variant evolved in a mixed-species biofilm with Acinetobacter sp. strain C6.Q35879451
Resistance mechanisms of multiresistant Pseudomonas aeruginosa strains from Germany and correlation with hypermutationQ36295397
Vibrio cholerae O1 El Tor: identification of a gene cluster required for the rugose colony type, exopolysaccharide production, chlorine resistance, and biofilm formationQ36456326
Endogenous oxidative stress produces diversity and adaptability in biofilm communitiesQ36858633
Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression.Q37074619
P. aeruginosa Biofilms in CF InfectionQ37176167
Pseudomonas aeruginosa rugose small-colony variants have adaptations that likely promote persistence in the cystic fibrosis lungQ37191781
Self-generated diversity produces "insurance effects" in biofilm communitiesQ37621081
Initiation of biofilm formation by Pseudomonas aeruginosa 57RP correlates with emergence of hyperpiliated and highly adherent phenotypic variants deficient in swimming, swarming, and twitching motilitiesQ39502437
Cell death in Pseudomonas aeruginosa biofilm development.Q39791484
Lack of association between hypermutation and antibiotic resistance development in Pseudomonas aeruginosa isolates from intensive care unit patientsQ39955018
Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infectionQ39997040
Emergence of phenotypic variants upon mismatch repair disruption in Pseudomonas aeruginosaQ40557981
Highly adherent small-colony variants of Pseudomonas aeruginosa in cystic fibrosis lung infection.Q40658282
Impact of mutS inactivation on foreign DNA acquisition by natural transformation in Pseudomonas stutzeriQ40731504
Two genetic loci produce distinct carbohydrate-rich structural components of the Pseudomonas aeruginosa biofilm matrixQ40993746
Genetic adaptation of Pseudomonas aeruginosa to the airways of cystic fibrosis patients is catalyzed by hypermutationQ41366386
Generation of virulence factor variants in Staphylococcus aureus biofilms.Q41776223
Occurrence of hypermutable Pseudomonas aeruginosa in cystic fibrosis patients is associated with the oxidative stress caused by chronic lung inflammationQ41825397
Hypermutation is a key factor in development of multiple-antimicrobial resistance in Pseudomonas aeruginosa strains causing chronic lung infectionsQ41974061
Characterization of colony morphology variants isolated from Pseudomonas aeruginosa biofilmsQ42105451
Heterogeneity of biofilms formed by nonmucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosisQ42561285
Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variationQ42674600
Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutantsQ43153453
Mismatch repair and the regulation of phase variation in Neisseria meningitidisQ43612705
Dynamics of adaptive microevolution of hypermutable Pseudomonas aeruginosa during chronic pulmonary infection in patients with cystic fibrosis.Q46002328
Increased mutability of Pseudomonas aeruginosa in biofilmsQ46767850
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectPseudomonas aeruginosaQ31856
biofilmQ467410
DNA mismatch repairQ2984243
P304page(s)e27842
P577publication date2011-11-17
P1433published inPLOS OneQ564954
P1476titleEvolution and adaptation in Pseudomonas aeruginosa biofilms driven by mismatch repair system-deficient mutators
P478volume6

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