scholarly article | Q13442814 |
P819 | ADS bibcode | 2014PLoSO...997008L |
P356 | DOI | 10.1371/JOURNAL.PONE.0097008 |
P932 | PMC publication ID | 4014593 |
P698 | PubMed publication ID | 24809695 |
P5875 | ResearchGate publication ID | 262189883 |
P2093 | author name string | Wan-Chen Huang | |
Tao-Shih Hsieh | |||
Yu-Shih Lin | |||
Mei-Shya Chen | |||
P2860 | cites work | Nuclease protection by Drosophila DNA topoisomerase II. Enzyme/DNA contacts at the strong topoisomerase II cleavage sites. | Q38342686 |
A two-drug model for etoposide action against human topoisomerase IIalpha | Q38359958 | ||
High-throughput assays for DNA gyrase and other topoisomerases | Q38756222 | ||
Interdomain communication in DNA topoisomerase II. DNA binding and enzyme activation. | Q40314755 | ||
Incomplete reversion of double stranded DNA cleavage mediated by Drosophila topoisomerase II: formation of single stranded DNA cleavage complex in the presence of an anti-tumor drug VM26 | Q40534513 | ||
Development and use of a high-throughput bacterial DNA gyrase assay to identify mammalian topoisomerase II inhibitors with whole-cell anticancer activity | Q44502489 | ||
Minimal DNA requirement for topoisomerase II-mediated cleavage in vitro | Q45169409 | ||
Double-stranded DNA cleavage/religation reaction of eukaryotic topoisomerase II: evidence for a nicked DNA intermediate | Q45387279 | ||
Single strand DNA cleavage reaction of duplex DNA by Drosophila topoisomerase II. | Q47070885 | ||
Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA. | Q51109804 | ||
Double strand DNA cleavage by type II DNA topoisomerase from Drosophila melanogaster | Q52518950 | ||
A homogeneous, high-throughput fluorescence anisotropy-based DNA supercoiling assay. | Q54377994 | ||
Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase II alpha in yeast | Q70467353 | ||
Betulinic acid and its derivatives, potent DNA topoisomerase II inhibitors, from the bark of Bischofia javanica | Q79455298 | ||
DNA topoisomerases: structure, function, and mechanism | Q22065417 | ||
Cellular roles of dna topoisomerases: a molecular perspective | Q22121990 | ||
Targeting DNA topoisomerase II in cancer chemotherapy | Q24649711 | ||
Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide | Q27670929 | ||
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays | Q28145712 | ||
DNA topoisomerases and their poisoning by anticancer and antibacterial drugs | Q28284744 | ||
Application of a novel microtitre plate-based assay for the discovery of new inhibitors of DNA gyrase and DNA topoisomerase VI | Q28486816 | ||
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition | Q29400901 | ||
High-throughput identification of antibacterials against methicillin-resistant Staphylococcus aureus (MRSA) and the transglycosylase | Q33746199 | ||
Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice | Q33851826 | ||
Tumor cell death induced by topoisomerase-targeting drugs. | Q34192665 | ||
Exploiting bacterial DNA gyrase as a drug target: current state and perspectives. | Q34214929 | ||
All tangled up: how cells direct, manage and exploit topoisomerase function | Q35154537 | ||
Interfacial inhibition of macromolecular interactions: nature's paradigm for drug discovery | Q36062585 | ||
Drosophila topoisomerase II double-strand DNA cleavage: analysis of DNA sequence homology at the cleavage site | Q36135719 | ||
Origin and evolution of DNA topoisomerases | Q36733344 | ||
Exploring DNA topoisomerases as targets of novel therapeutic agents in the treatment of infectious diseases | Q36754740 | ||
Real-time detection of DNA topological changes with a fluorescently labeled cruciform. | Q37012979 | ||
Bacterial topoisomerase I as a target for discovery of antibacterial compounds | Q37108422 | ||
The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing | Q37108461 | ||
DNA topoisomerases: harnessing and constraining energy to govern chromosome topology | Q37255381 | ||
New mechanistic and functional insights into DNA topoisomerases. | Q38089800 | ||
DNA topoisomerase poisons as antitumor drugs | Q38286727 | ||
A high-throughput-compatible, fluorescence anisotropy-based assay for ATP-dependent supercoiled DNA relaxation by human topoisomerase IIα. | Q38317625 | ||
A role for the passage helix in the DNA cleavage reaction of eukaryotic topoisomerase II. A two-site model for enzyme-mediated DNA cleavage | Q38331051 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | e97008 | |
P577 | publication date | 2014-01-01 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Toward discovering new anti-cancer agents targeting topoisomerase IIα: a facile screening strategy adaptable to high throughput platform | |
P478 | volume | 9 |
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