scholarly article | Q13442814 |
P819 | ADS bibcode | 2014PLoSO...990637S |
P356 | DOI | 10.1371/JOURNAL.PONE.0090637 |
P932 | PMC publication ID | 3946170 |
P698 | PubMed publication ID | 24603686 |
P5875 | ResearchGate publication ID | 260610876 |
P50 | author | Khushboo Bafna | Q59692215 |
Shantanu Shukla | Q59692225 | ||
P2093 | author name string | Durai Sundar | |
Sunil S Thorat | |||
P2860 | cites work | Comparing the suitability of autodock, gold and glide for the docking and predicting the possible targets of Ru(II)-based complexes as anticancer agents | Q86489694 |
Antihepatotoxic activity of Swertia chirata on paracetamol and galactosamine induced hepatotoxicity in rats | Q93921351 | ||
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing | Q24563789 | ||
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis | Q24646764 | ||
The cyclooxygenases | Q24801433 | ||
Basic local alignment search tool | Q25938991 | ||
Structural insights into the stereochemistry of the cyclooxygenase reaction | Q27622531 | ||
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents | Q27734207 | ||
PRODRG: a tool for high-throughput crystallography of protein-ligand complexes | Q27860633 | ||
Multiple sequence alignment with hierarchical clustering | Q27860956 | ||
The Protein Data Bank: a computer-based archival file for macromolecular structures | Q27860989 | ||
The mechanism of action of aspirin | Q28165886 | ||
Non-steroidal anti-inflammatory drug use and the risk of gastric cancer: a systematic review and meta-analysis | Q28166328 | ||
Prostate cancer and use of nonsteroidal anti-inflammatory drugs: systematic review and meta-analysis | Q28166676 | ||
Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs | Q28174919 | ||
Protective association of aspirin/NSAIDs and esophageal cancer: a systematic review and meta-analysis | Q28194560 | ||
The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential | Q28195754 | ||
Cyclooxygenase enzymes: catalysis and inhibition | Q28212483 | ||
Indomethacin and aspirin abolish prostaglandin release from the spleen | Q28251299 | ||
Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway | Q28279767 | ||
ChemSpider: An Online Chemical Information Resource | Q28842739 | ||
Approximate atomic surfaces from linear combinations of pairwise overlaps (LCPO) | Q29012795 | ||
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility | Q29547658 | ||
Verification of protein structures: patterns of nonbonded atomic interactions | Q29615613 | ||
Cyclooxygenases 1 and 2 | Q29615645 | ||
GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit | Q29615867 | ||
VERIFY3D: assessment of protein models with three-dimensional profiles | Q29615886 | ||
Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models | Q29616389 | ||
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs | Q29617192 | ||
Update on activities at the Universal Protein Resource (UniProt) in 2013 | Q29617361 | ||
Protein structure modeling with MODELLER | Q29617759 | ||
Binding of a diverse set of ligands to avidin and streptavidin: an accurate quantitative prediction of their relative affinities by a combination of molecular mechanics and continuum solvent models | Q31446320 | ||
Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2. | Q31842803 | ||
Ajoene, a natural product with non-steroidal anti-inflammatory drug (NSAID)-like properties? | Q32139513 | ||
Combining docking and molecular dynamic simulations in drug design | Q33245994 | ||
Evaluation of the in-vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms | Q33883057 | ||
Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity | Q33939152 | ||
Generalized born models of macromolecular solvation effects | Q34059768 | ||
Cyclooxygenase-2: a therapeutic target | Q34111944 | ||
Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation | Q34338138 | ||
Amarogentin, a naturally occurring secoiridoid glycoside and a newly recognized inhibitor of topoisomerase I from Leishmania donovani. | Q34412486 | ||
Assessing the performance of the MM/PBSA and MM/GBSA methods. 1. The accuracy of binding free energy calculations based on molecular dynamics simulations | Q34531578 | ||
Many actions of cyclooxygenase-2 in cellular dynamics and in cancer | Q34539982 | ||
TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue | Q34584790 | ||
The human bitter taste receptor hTAS2R50 is activated by the two natural bitter terpenoids andrographolide and amarogentin | Q35007309 | ||
Cyclooxygenase 2: a molecular target for cancer prevention and treatment | Q35057356 | ||
Cyclooxygenase-2 Biology | Q35551907 | ||
Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor kappa B (NF-kappaB). | Q35634667 | ||
Swertia (Gentianaceae): chemical and pharmacological aspects | Q36693606 | ||
Calculation of protein-ligand binding affinities. | Q36698596 | ||
Plant-derived compounds in clinical trials | Q37085090 | ||
Salicylic Acid, a multifaceted hormone to combat disease. | Q37462957 | ||
The mode of action of aspirin-like drugs | Q39616454 | ||
Suppression of fever at near term is associated with reduced COX-2 protein expression in rat hypothalamus. | Q40576567 | ||
Constitutive cyclooxygenase-2 expression in healthy human and rabbit gastric mucosa. | Q42460880 | ||
Phenolic-linked biochemical rationale for the anti-diabetic properties of Swertia chirayita (Roxb. ex Flem.) Karst | Q44346144 | ||
Evaluation of the anticarcinogenic activity of Swertia chirata Buch.Ham, an Indian medicinal plant, on DMBA-induced mouse skin carcinogenesis model | Q44918518 | ||
Amarogentin can reduce hyperproliferation by downregulation of Cox-II and upregulation of apoptosis in mouse skin carcinogenesis model | Q46975485 | ||
Antihepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats | Q48768392 | ||
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. | Q52518083 | ||
MMPBSA decomposition of the binding energy throughout a molecular dynamics simulation of amyloid-beta (Abeta(10-35)) aggregation. | Q64964970 | ||
Aspirin selectively inhibits prostaglandin production in human platelets | Q71062251 | ||
Expression of cyclooxygenase-2 and nitrotyrosine in human gastric mucosa before and after Helicobacter pylori eradication | Q73220554 | ||
Prevention of liver carcinogenesis by amarogentin through modulation of G1/S cell cycle check point and induction of apoptosis | Q84935327 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Swertia chirayita | Q21318003 |
P304 | page(s) | e90637 | |
P577 | publication date | 2014-03-06 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | The bitter barricading of prostaglandin biosynthesis pathway: understanding the molecular mechanism of selective cyclooxygenase-2 inhibition by amarogentin, a secoiridoid glycoside from Swertia chirayita | |
P478 | volume | 9 |
Q51604196 | Chinese medicine amygdalin and β-glucosidase combined with antibody enzymatic prodrug system as a feasible antitumor therapy. |
Q38295078 | Design and evaluation of an apta-nano-sensor to detect Acetamiprid in vitro and in silico. |
Q57287548 | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics |
Q115707320 | Integrative Analytical and Computational Strategies for Qualitative and Semi-quantitative Plant Metabolome Characterization |
Search more.