| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Yang Cao | |
| Stephen M Prescott | |||
| P433 | issue | 3 | |
| P304 | page(s) | 279-286 | |
| P577 | publication date | 2002-03-01 | |
| P1433 | published in | Journal of Cellular Physiology | Q1524270 |
| P1476 | title | Many actions of cyclooxygenase-2 in cellular dynamics and in cancer | |
| P478 | volume | 190 |
| Q33869492 | -765G > C COX-2 polymorphism may be a susceptibility marker for gastric adenocarcinoma in patients with atrophy or intestinal metaplasia. |
| Q40641379 | A conditionally replicating adenovirus targeted to tumor cells through activated RAS/P-MAPK-selective mRNA stabilization. |
| Q40582627 | A cyclooxygenase-2 promoter-based conditionally replicating adenovirus with enhanced infectivity for treatment of ovarian adenocarcinoma |
| Q55012542 | A drug combination targeting hypoxia induced chemoresistance and stemness in glioma cells. |
| Q48045028 | A small amount of cyclooxygenase 2 (COX2) is constitutively expressed in platelets |
| Q58113811 | Abnormal activation of the Akt signaling pathway in adenoid cystic carcinoma |
| Q42777131 | Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation. |
| Q36393246 | Adenovirus type 5 E1A-induced apoptosis in COX-2-overexpressing breast cancer cells |
| Q25255846 | Allellic variants in regulatory regions of cyclooxygenase-2: association with advanced colorectal adenoma |
| Q90121629 | Aloperine suppresses LPS-induced macrophage activation through inhibiting the TLR4/NF-κB pathway |
| Q28394475 | Altered prostanoid signaling contributes to increased skin tumorigenesis in Tpl2 knockout mice |
| Q55324540 | Analysis of the in vitro effects of di-(2-ethylhexyl) phthalate exposure on human uterine leiomyoma cells. |
| Q40086787 | Anti-apoptotic effects of arachidonic acid and prostaglandin E2 in pancreatic beta-cells. |
| Q34361606 | Anti-cancer effects of celecoxib on nasopharyngeal carcinoma HNE-1 cells expressing COX-2 oncoprotein |
| Q36424321 | Antitumor effect of the selective COX-2 inhibitor celecoxib on endometrial adenocarcinoma in vitro and in vivo |
| Q35123623 | Arachidonic acid cytotoxicity: can arachidonic acid be a physiological mediator of cell death? |
| Q35586837 | Aromatase and cyclooxygenases: enzymes in breast cancer |
| Q40183471 | Ascorbic acid-pretreated quartz enhances cyclo-oxygenase-2 expression in RAW 264.7 murine macrophages |
| Q64242874 | Association between rs20417 polymorphism in cyclooxygenase-2 and gastric cancer susceptibility: Evidence from15 case-control studies |
| Q35156482 | Autocrine prostaglandin E₂ signaling promotes promonocytic leukemia cell survival via COX-2 expression and MAPK pathway |
| Q39034043 | Autophagy in UV Damage Response |
| Q38413564 | Bilharzial vs non‐bilharzial related bladder cancer: pathological characteristics and value of cyclooxygenase‐2 expression |
| Q35052847 | Biological roles of CCAAT/Enhancer-binding protein delta during inflammation |
| Q39633227 | COX-2 Gene increases tongue cancer cell proliferation and invasion through VEGF-C pathway |
| Q38443121 | COX-2 expression in DCIS: correlation with VEGF, HER-2/neu, prognostic molecular markers and clinicopathological features. |
| Q33930978 | COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status |
| Q35753467 | COX-2 inhibition in cancer therapeutics: a field of controversy or a magic bullet? |
| Q34984281 | COX-2-765G>C polymorphism increases the risk of cancer: a meta-analysis |
| Q36819371 | Cancer cell signaling pathways targeted by spice-derived nutraceuticals |
| Q42913622 | Carnosic acid inhibits the proliferation and migration capacity of human colorectal cancer cells |
| Q38998361 | Celecoxib prevents curcumin-induced apoptosis in a hematopoietic cancer cell model. |
| Q39377146 | Celecoxib radiosensitizes the human cervical cancer HeLa cell line via a mechanism dependent on reduced cyclo-oxygenase-2 and vascular endothelial growth factor C expression |
| Q43295259 | Celecoxib treatment reduces peritoneal fibrosis and angiogenesis and prevents ultrafiltration failure in experimental peritoneal dialysis |
| Q36185641 | Chemoprevention of lung cancer: concepts and strategies |
| Q35150327 | Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of a 12R-LOX-chaperone complex |
| Q39647685 | Combined Inhibitory Effects of Celecoxib and Fluvastatin on the Growth of Human Hepatocellular Carcinoma Xenografts in Nude Mice |
| Q26786180 | Common Variants of the Prostaglandin-Endoperoxide Synthase 2 Gene and Hepatocellular Carcinoma Susceptibility |
| Q54561459 | Common polymorphisms in 5-lipoxygenase and 12-lipoxygenase genes and the risk of incident, sporadic colorectal adenoma. |
| Q42492517 | Comparison of PTCH1, COX-2, p53, and Ki-67 protein expression in basal cell carcinomas of nodular and superficial subtypes arising on the head and trunk |
| Q42455147 | Correlation and expression of COX-2 and P53 protein in basal cell carcinoma of eyelid |
| Q36190324 | Correlation between expression of cyclooxygenase-2 and the presence of inflammatory cells in human primary hepatocellular carcinoma: possible role in tumor promotion and angiogenesis |
| Q39001013 | Cyclooxygenase 2 (rs2745557) Polymorphism and the Susceptibility to Benign Prostate Hyperplasia and Prostate Cancer in Egyptians |
| Q35011895 | Cyclooxygenase 2 selective inhibitors in cancer treatment and prevention |
| Q44582774 | Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition |
| Q43210244 | Cyclooxygenase-2 -1195G>A (rs689466) polymorphism and cancer susceptibility: an updated meta-analysis involving 50,672 subjects |
| Q35081466 | Cyclooxygenase-2 and B-cell lymphoma-2 expression in cystitis glandularis and primary vesicle adenocarcinoma |
| Q33659189 | Cyclooxygenase-2 and p53 expression as prognostic indicators in conventional renal cell carcinoma |
| Q36179801 | Cyclooxygenase-2 expression and angiogenesis in colorectal cancer |
| Q73437468 | Cyclooxygenase-2 expression in human pituitary tumors |
| Q44269055 | Cyclooxygenase-2 inhibits tumor necrosis factor alpha-mediated apoptosis in renal glomerular mesangial cells |
| Q33503521 | Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trial |
| Q39189510 | Cyclooxygenase-2 positively regulates Akt signalling and enhances survival of erythroleukemia cells exposed to anticancer agents. |
| Q35077006 | Cyclooxygenase-2: a therapeutic target in angiogenesis. |
| Q42726279 | Cyclooxygenases in hepatocellular carcinoma. |
| Q39203258 | Cyclopamine and jervine induce COX-2 overexpression in human erythroleukemia cells but only cyclopamine has a pro-apoptotic effect. |
| Q47114856 | Diagnostic investigations of PLA2G16 and CDH11 expression levels as independent prognostic markers of human osteosarcoma |
| Q44620955 | Dietary alpha-linolenic acid reduces COX-2 expression and induces apoptosis of hepatoma cells. |
| Q34761843 | Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion |
| Q26751157 | Discoidin Domain Receptors: Potential Actors and Targets in Cancer |
| Q37754720 | Eicosanoids in inflammation and cancer: the role of COX-2. |
| Q33855260 | Embryonic expression of cyclooxygenase-2 causes malformations in axial skeleton |
| Q92327192 | Endoplasmic Reticulum Stress-Induced Resistance to Doxorubicin Is Reversed by Mulberry Leaf Polyphenol Extract in Hepatocellular Carcinoma through Inhibition of COX-2 |
| Q40524016 | Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinase |
| Q45107794 | Endothelial cell confluence regulates cyclooxygenase-2 and prostaglandin E2 production that modulate motility. |
| Q34302223 | Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1 |
| Q40017793 | Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulation of E-cadherin and has antitumor effect on human bladder cancer cells in vitro and in vivo. |
| Q51812877 | Evaluation of COX-2, EGFR, and p53 as biomarkers of non-dysplastic oral leukoplakias. |
| Q33869146 | Expression of 5-lipoxygenase in human colorectal cancer |
| Q47614613 | Expression of COX-2 is increased with age in papillary thyroid cancer. |
| Q37476188 | Expression of Cyclooxygenase-2 and Bcl-2 in human gastric adenomas |
| Q53630022 | Expression of cyclooxygenase-2 in adenocarcinomas of the uterine cervix and its relation to angiogenesis and tumor growth. |
| Q34605197 | Expression of cyclooxygenase-2 in colorectal cancer and its clinical significance |
| Q33868003 | Expression of cyclooxygenase-2 is associated with p53 accumulation in premalignant and malignant gallbladder lesions |
| Q35213252 | Future directions in the management of ovarian cancer |
| Q35741628 | Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers. |
| Q38418321 | High dietary arachidonic acid levels affect the process of eye migration and head shape in pseudoalbino Senegalese sole Solea senegalensis early juveniles. |
| Q34610297 | Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kappaB and AP-1: IkappaB kinase and c-Jun-N-terminal kinase as respective potential upstream targets |
| Q24320080 | IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis |
| Q39299375 | IL1β-mediated Stromal COX-2 signaling mediates proliferation and invasiveness of colonic epithelial cancer cells |
| Q52061798 | Identification of differentially regulated genes during elongation and early implantation in the ovine trophoblast using complementary DNA array screening. |
| Q28165527 | Increased NF-κB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells |
| Q57070511 | Inflammatory gene mRNA expression in human peripheral blood and its association with colorectal cancer |
| Q33596371 | Influence of age and gender on association between -765G > C COX-2 genetic polymorphism and gastric adenocarcinoma risk: a case-control study in Iran |
| Q40618173 | Inhibition of Phorbol Ester–Induced COX-2 Expression by Epigallocatechin Gallate in Mouse Skin and Cultured Human Mammary Epithelial Cells |
| Q35171200 | Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2 |
| Q40618107 | Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-Penta-O-galloyl-β-D-glucose in murine macrophage cells |
| Q33577982 | Inhibitory Effect of IFN-beta, on the Antitumor Activity of Celecoxib in U87 Glioma Model |
| Q36695052 | Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: the Singapore Chinese Health Study |
| Q33813699 | Jacalin Has Chemopreventive Effects on Colon Cancer Development. |
| Q48229709 | Late administration of a specific COX-2 inhibitor does not treat and/or prevent progression of gastric tumors in rats submitted to duodenogastric reflux procedure |
| Q24800010 | Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer |
| Q26850218 | Lung cancer: a classic example of tumor escape and progression while providing opportunities for immunological intervention |
| Q37185003 | Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells. |
| Q36756158 | Malignancy associated with the use of intestinal segments in the urinary tract |
| Q43245354 | Marine Sponge Natural Products with Anticancer Potential: An Updated Review |
| Q37330050 | Marine n-3 and saturated fatty acids in relation to risk of colorectal cancer in Singapore Chinese: a prospective study |
| Q52685362 | Matrine Induction of ROS Mediated Apoptosis in Human ALL B-lymphocytes Via Mitochondrial Targeting |
| Q34704784 | Mechanisms of oxysterol-induced carcinogenesis. |
| Q37875160 | Mechanisms of resistance to photodynamic therapy |
| Q36336831 | Mechanistic aspects of COX-2 expression in colorectal neoplasia |
| Q41145128 | Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells. |
| Q40722888 | Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors |
| Q42705756 | Modulator effects of meloxicam against doxorubicin-induced nephrotoxicity in mice. |
| Q37349574 | Multi-Target Approaches in Colon Cancer Chemoprevention Based on Systems Biology of Tumor Cell-Signaling. |
| Q37772725 | NSAIDs and cardiovascular disease: transducing human pharmacology results into clinical read-outs in the general population |
| Q38991887 | Niflumic acid affects store-operated Ca(2+)-permeable (SOC) and Ca (2+)-dependent K (+) and Cl (-) ion channels and induces apoptosis in K562 cells |
| Q36262238 | Niflumic acid exhibits anti-tumor activity in nasopharyngeal carcinoma cells through affecting the expression of ERK1/2 and the activity of MMP2 and MMP9 |
| Q33664095 | Non-Steroidal Anti-Inflammatory Drugs in the Carcinogenesis of the Gastrointestinal Tract |
| Q24197474 | Non-steroidal anti-inflammatory agents to induce regression and prevent the progression of cervical intraepithelial neoplasia |
| Q50065350 | Non-steroidal anti-inflammatory agents to induce regression and prevent the progression of cervical intraepithelial neoplasia. |
| Q28195436 | Nonsteroidal anti-inflammatory drugs in colorectal cancer: from prevention to therapy |
| Q35640641 | Novel approaches to treat asymptomatic, hormone-naive patients with rising prostate-specific antigen after primary treatment for prostate cancer |
| Q38998679 | Odontogenic epithelial proliferation is correlated with COX-2 expression in dentigerous cyst and ameloblastoma |
| Q28195678 | Oesophageal squamous cell neoplasia in head and neck cancer patients: upregulation of COX-2 during carcinogenesis |
| Q35770111 | Overexpression of cyclo-oxygenase-2 is an independent predictor of unfavourable outcome in node-negative breast cancer, but is not associated with protein kinase B (Akt) and mitogen-activated protein kinase (ERK1/2, p38) activation or with Her-2/neu |
| Q53599778 | Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development. |
| Q33752909 | PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-beta signaling during mammary tumorigenesis |
| Q35620647 | PLA2G16 Expression in Human Osteosarcoma Is Associated with Pulmonary Metastasis and Poor Prognosis |
| Q38902303 | PTGS2 (COX-2) -765 G > C functional promoter polymorphism and its association with risk and lymph node metastasis in nasopharyngeal carcinoma. |
| Q33705238 | PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3). |
| Q35843339 | Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells |
| Q39586846 | Paulistine--The Functional Duality of a Wasp Venom Peptide Toxin |
| Q35120350 | PharmGKB summary: very important pharmacogene information for PTGS2. |
| Q42828953 | Phosphatidylinositol transfer protein alpha regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor |
| Q51102871 | Piceatannol inhibits phorbol ester-induced expression of COX-2 and iNOS in HR-1 hairless mouse skin by blocking the activation of NF-κB and AP-1. |
| Q44955215 | Pilot study of celecoxib and infusional 5-fluorouracil as second-line treatment for advanced pancreatic carcinoma |
| Q28385642 | Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability |
| Q55014420 | Plasma fatty acids and risk of colon and rectal cancers in the Singapore Chinese Health Study. |
| Q37220827 | Polymorphism of -765G > C COX-2 is a risk factor for gastric adenocarcinoma and peptic ulcer disease in addition to H pylori infection: a study from northern India |
| Q34801350 | Polyunsaturated fatty acids (PUFA) and eicosanoids in human health and pathologies |
| Q38282100 | Potency of non-steroidal anti-inflammatory drugs in chemotherapy. |
| Q39710330 | Potential role of cyclooxygenase-2 on the regulation of the drug efflux transporter ABCG2 in breast cancer cell lines |
| Q37769274 | Potentially functional COX-2-1195G>A polymorphism increases the risk of digestive system cancers: a meta-analysis |
| Q36858103 | Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells. |
| Q82718017 | Protective effect of Cox-2 allelic variants on risk of colorectal adenoma development in African Americans |
| Q39469974 | R-flurbiprofen, a novel nonsteroidal anti-inflammatory drug, decreases cell proliferation and induces apoptosis in pituitary adenoma cells in vitro |
| Q39791161 | ROCK and nuclear factor-kappaB-dependent activation of cyclooxygenase-2 by Rho GTPases: effects on tumor growth and therapeutic consequences |
| Q40087518 | Radiosensitization of human glioma cells by cyclooxygenase-2 (COX-2) inhibition: independent on COX-2 expression and dependent on the COX-2 inhibitor and sequence of administration. |
| Q35921577 | Rationale for use of cyclooxygenase-2 inhibitors in prevention and treatment of bladder cancer |
| Q36070440 | Reactive oxygen species and lung tumorigenesis by mutant K-ras: a working hypothesis |
| Q38388872 | Relationship between tumour angiogenesis and expression of cyclo-oxygenase-2 and vascular endothelial growth factor-A in human renal cell carcinoma |
| Q46941211 | Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity |
| Q38849334 | Retinoic acid morpholine amide (RAMA) inhibits expression of Fas ligand through EP1 receptor in colon cancer cells |
| Q36544952 | RhoGDI deficiency induces constitutive activation of Rho GTPases and COX-2 pathways in association with breast cancer progression |
| Q84153148 | Role of heme oxygenase-1 in inflammatory response induced by mechanical stretch in synovial cells |
| Q41765274 | Screen and analysis of key disease genes for precancerous lesions of oral buccal mucosa induced by DMBA in golden hamsters |
| Q38797633 | Secretion of IL-1β from imatinib-resistant chronic myeloid leukemia cells contributes to BCR-ABL mutation-independent imatinib resistance. |
| Q43868181 | Serum carcino-embryonic antigen (CEA) and its possible use as tumor marker for secondary tumors in urinary intestinal reservoirs |
| Q53362473 | Significance of COX-2 expression in human renal cell carcinoma. |
| Q45215951 | Silibinin inhibits tumor promotional triggers and tumorigenesis against chemically induced two-stage skin carcinogenesis in Swiss albino mice: possible role of oxidative stress and inflammation |
| Q55534659 | Single nucleotide polymorphism rs4648298 in miRNAs hsa-miR21 and hsa-miR590 binding site of COX gene is a strong colorectal cancer determinant. |
| Q54433912 | Study on the association of COX-2 genetic polymorphisms with risk of gastric cancer in high incidence Hexi area of Gansu province in China. |
| Q36959617 | Sumoylation of LAP1 is involved in the HDAC4-mediated repression of COX-2 transcription. |
| Q38051084 | Systematic review and meta-analysis of COX-2 expression and polymorphisms in prostate cancer |
| Q21144267 | Systemic therapy for cervical cancer with potentially regulatable oncolytic adenoviruses |
| Q39123466 | TNFα-activated stromal COX-2 signalling promotes proliferative and invasive potential of colon cancer epithelial cells |
| Q38710579 | The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells. |
| Q21342813 | The Role of PPARgamma Receptors and Leukotriene B(4) Receptors in Mediating the Effects of LY293111 in Pancreatic Cancer |
| Q42157330 | The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage |
| Q28540582 | The bitter barricading of prostaglandin biosynthesis pathway: understanding the molecular mechanism of selective cyclooxygenase-2 inhibition by amarogentin, a secoiridoid glycoside from Swertia chirayita |
| Q38103868 | The effect of vascular endothelial growth factor in the progression of bladder cancer and diabetic retinopathy |
| Q37795885 | The impact of cyclooxygenase inhibition on duodenal motility and mucosal alkaline secretion in anaesthetized rats |
| Q33737469 | The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies. |
| Q38339764 | Transcriptional regulation of cyclooxygenase-2 gene in pancreatic beta-cells |
| Q34156486 | Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis |
| Q40626539 | Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells |
| Q36026163 | Utility of immunohistochemical analysis for cyclo-oxygenase 2 in the differential diagnosis of osteoblastoma and osteosarcoma |
| Q33518570 | VEGF gene expression in adult human thymus fat: a correlative study with hypoxic induced factor and cyclooxygenase-2 |
| Q35289963 | Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2. |
| Q45286157 | [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin |
| Q39334198 | iNOS signaling interacts with COX-2 pathway in colonic fibroblasts |
| Q43181472 | miR-21 inhibits the effects of cyclooxygenase-2 inhibitor NS398 on apoptosis and invasion in gastric cancer cells. |
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