The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells.

scientific article

The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/JOP.12572
P698PubMed publication ID28342204

P50authorBo YangQ87669208
P2093author name stringWeizhong Li
Xiaohui Li
Guoxu Han
P2860cites workCDK inhibitors: positive and negative regulators of G1-phase progressionQ27860983
Celecoxib for the prevention of sporadic colorectal adenomasQ28200368
Prostaglandin E2/EP1 signaling pathway enhances intercellular adhesion molecule 1 (ICAM-1) expression and cell motility in oral cancer cellsQ30430640
Role of beta-arrestin 1 in the metastatic progression of colorectal cancerQ34335080
A role for COX2-derived PGE2 and PGE2-receptor subtypes in head and neck squamous carcinoma cell proliferation.Q34348741
Many actions of cyclooxygenase-2 in cellular dynamics and in cancerQ34539982
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasionQ34646962
EP2 and EP4 prostanoid receptor signalingQ35579608
Downregulation of prostaglandin E receptor subtype EP3 during colon cancer developmentQ35596716
Targeting COX-2 and EP4 to control tumor growth, angiogenesis, lymphangiogenesis and metastasis to the lungs and lymph nodes in a breast cancer modelQ39340968
Inhibitive effect of celecoxib on the adhesion and invasion of human tongue squamous carcinoma cells to extracellular matrix via down regulation of MMP-2 expressionQ39667462
Expression of prostaglandin E2 receptors in oral squamous cell carcinomas and growth inhibitory effects of an EP3 selective antagonist, ONO-AE3-240.Q39884442
EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathwaysQ40154550
Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation.Q40559845
Prostaglandin E2 increases growth and motility of colorectal carcinoma cellsQ43559615
Overexpression of cyclooxygenase-2 is associated with radioresistance in oral squamous cell carcinomaQ44768299
Celecoxib: a potent cyclooxygenase-2 inhibitor in cancer prevention.Q50933253
Suppression of azoxymethane-induced colon cancer development in rats by a prostaglandin E receptor EP1-selective antagonist.Q53357845
Cyclin-dependent kinases and cell-cycle transitions: does one fit all?Q53451934
Overexpression of COX-2 gene in oral cancer is independent of stage of disease and degree of differentiation.Q54541146
P433issue10
P304page(s)991-997
P577publication date2017-04-11
P1433published inJournal of Oral Pathology & MedicineQ15724686
P1476titleThe EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells
P478volume46

Search more.