scholarly article | Q13442814 |
P50 | author | Jorge Z. Torres | Q47474680 |
P2093 | author name string | Yong Huang | |
Robert Damoiseaux | |||
Chien-Ming Li | |||
Silvia Senese | |||
Yu-Chen Lo | |||
Qiyang Hu | |||
P2860 | cites work | Open Babel: An open chemical toolbox | Q21198766 |
Identification of Direct Protein Targets of Small Molecules | Q21558640 | ||
The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly | Q24299186 | ||
Privileged scaffolds for library design and drug discovery | Q24604575 | ||
Network-based prediction of protein function | Q24670295 | ||
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets | Q24794040 | ||
Microtubule-binding agents: a dynamic field of cancer therapeutics | Q27690249 | ||
Optimal assignment methods for ligand-based virtual screening | Q27998698 | ||
PubChem as a public resource for drug discovery | Q28111749 | ||
Receptor and nonreceptor protein tyrosine phosphatases in the nervous system | Q28185491 | ||
Protein tyrosine phosphatases: mechanisms of catalysis and regulation | Q28288979 | ||
ChEMBL: a large-scale bioactivity database for drug discovery | Q28315179 | ||
SCD1 Inhibition Causes Cancer Cell Death by Depleting Mono-Unsaturated Fatty Acids | Q28481634 | ||
PubChem: a public information system for analyzing bioactivities of small molecules | Q28842768 | ||
Drug-target network | Q29614447 | ||
Exploring polypharmacology using a ROCS-based target fishing approach | Q45783965 | ||
Robust ligand-based modeling of the biological targets of known drugs | Q46202116 | ||
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach | Q46702612 | ||
A high-throughput model for screening anti-tumor agents capable of promoting polymerization of tubulin in vitro. | Q47415501 | ||
Global protein function prediction from protein-protein interaction networks | Q47921995 | ||
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. | Q47967639 | ||
Molecular similarity in medicinal chemistry. | Q54708065 | ||
Database searching for compounds with similar biological activity using short binary bit string representations of molecules | Q73103011 | ||
Structure-activity relationship anatomy by network-like similarity graphs and local structure-activity relationship indices | Q81979863 | ||
Dual ACE/NEP inhibitors - more than playing the ACE card | Q82860693 | ||
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes | Q29615188 | ||
Relating protein pharmacology by ligand chemistry | Q29617492 | ||
A network of protein-protein interactions in yeast | Q30004209 | ||
Discovery of a Novel Series of Inhibitors of Lymphoid Tyrosine Phosphatase with Activity in Human T Cells | Q30500024 | ||
ABL1 regulates spindle orientation in adherent cells and mammalian skin. | Q30512982 | ||
Assessment of prediction accuracy of protein function from protein--protein interaction data | Q30644168 | ||
Bridging chemical and biological space: "target fishing" using 2D and 3D molecular descriptors | Q33265869 | ||
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds | Q33351239 | ||
Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part I: Discovery of 3-(2-hydroxyethoxy)-4-methoxy-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide. | Q33470986 | ||
Target profiling of small molecules by chemical proteomics | Q33494810 | ||
Target fishing for chemical compounds using target-ligand activity data and ranking based methods | Q33504757 | ||
Finding key members in compound libraries by analyzing networks of molecules assembled by structural similarity | Q33514030 | ||
Protein function in the post-genomic era. | Q33906809 | ||
PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach | Q33957682 | ||
Identifying compound-target associations by combining bioactivity profile similarity search and public databases mining | Q33990658 | ||
MetaMapp: mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity | Q34271370 | ||
Development of antibiotic activity profile screening for the classification and discovery of natural product antibiotics. | Q34487377 | ||
Target identification of small molecules based on chemical biology approaches | Q34564656 | ||
Mapping the cellular response to small molecules using chemogenomic fitness signatures | Q34626429 | ||
Target identification and mechanism of action in chemical biology and drug discovery | Q34626974 | ||
TarFisDock: a web server for identifying drug targets with docking approach | Q34974340 | ||
Chemical informatics and target identification in a zebrafish phenotypic screen. | Q35683136 | ||
Modeling cellular machinery through biological network comparison | Q36443509 | ||
SuperPred: drug classification and target prediction | Q36749406 | ||
TargetHunter: An In Silico Target Identification Tool for Predicting Therapeutic Potential of Small Organic Molecules Based on Chemogenomic Database | Q36910563 | ||
Target deconvolution strategies in drug discovery | Q36961595 | ||
A ligand-based approach to mining the chemogenomic space of drugs | Q37270761 | ||
Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds | Q37536897 | ||
Virtual Affinity Fingerprints for Target Fishing: A New Application of Drug Profile Matching | Q38065183 | ||
Tools for in silico target fishing | Q38256258 | ||
Discovery and evaluation of dual CDK1 and CDK2 inhibitors | Q40291591 | ||
BLASTing small molecules--statistics and extreme statistics of chemical similarity scores | Q41940392 | ||
DINIES: drug-target interaction network inference engine based on supervised analysis. | Q42044276 | ||
Exploiting indirect neighbours and topological weight to predict protein function from protein-protein interactions | Q42683787 | ||
Competitive mass spectrometry binding assay for characterization of three binding sites of tubulin. | Q42918547 | ||
Rapid Shape-Based Ligand Alignment and Virtual Screening Method Based on Atom/Feature-Pair Similarities and Volume Overlap Scoring | Q44001483 | ||
Ligand-target prediction using Winnow and naive Bayesian algorithms and the implications of overall performance statistics | Q44134194 | ||
ChemMapper: a versatile web server for exploring pharmacology and chemical structure association based on molecular 3D similarity method. | Q44385818 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | Cytoscape | Q3699942 |
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | e1004153 | |
P577 | publication date | 2015-03-01 | |
P1433 | published in | PLOS Computational Biology | Q2635829 |
P1476 | title | Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens | |
P478 | volume | 11 |
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Q92594995 | Dissecting the mechanisms of cell division |
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Q41045664 | Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division |
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