Novel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation Phenotypes

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Novel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation Phenotypes is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1155812C
P356DOI10.1371/JOURNAL.PONE.0155812
P3181OpenCitations bibliographic resource ID1290018
P932PMC publication ID4880214
P698PubMed publication ID27224051

P50authorAshley N TurnerQ59705598
Anil K ChallaQ59705604
P2093author name stringRobert A Kesterson
Evan R Boitet
Daniel Kennedy
Alecia K Gross
Larry W Johnson
Ethan R Downs
Katherine M Hymel
P2860cites workTyrosinase subcellular distribution and kinetic parameters in wild type and C-locus mutant C57BL/6J miceQ71571211
Efficient genome editing in zebrafish using a CRISPR-Cas systemQ24610828
A tyrosinase gene missense mutation in temperature-sensitive type I oculocutaneous albinism. A human homologue to the Siamese cat and the Himalayan mouseQ24619568
Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome EditingQ26770012
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineeringQ29615505
DNA targeting specificity of RNA-guided Cas9 nucleasesQ29615793
Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotesQ34200242
Genome editing using artificial site-specific nucleases in zebrafishQ34377164
Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editingQ34960598
Dissection of a mouse eye for a whole mount of the retinal pigment epitheliumQ35396380
Molecular basis of mouse Himalayan mutationQ35559382
Functional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR-Cas9-mediated mutagenesisQ35656786
A structural role for arginine in proteins: multiple hydrogen bonds to backbone carbonyl oxygensQ36278743
Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease systemQ37117695
Engineering subtle targeted mutations into the mouse genomeQ38126465
Arginyl Residues: Anion Recognition Sites in EnzymesQ40053375
Efficient identification of TALEN-mediated genome modifications using heteroduplex mobility assays.Q40286329
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectCas9Q16965677
CRISPR-Cas methodQ17310682
CRISPRQ412563
P304page(s)e0155812
P577publication date2016-01-01
P1433published inPLOS OneQ564954
P1476titleNovel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation Phenotypes
P478volume11

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cites work (P2860)
Q90568619Analysis of novel domain-specific mutations in the zebrafish ndr2/cyclops gene generated using CRISPR-Cas9 RNPs
Q46275669Epigenetic modification of miR-663 controls mitochondria-to-nucleus retrograde signaling and tumor progression
Q55160430First Year Course-Based Undergraduate Research Experience (CURE) Using the CRISPR/Cas9 Genome Engineering Technology in Zebrafish.
Q50195843Identification and characterization of the tyrosinase gene (TYR) and its transcript variants (TYR_1 and TYR_2) in the crab-eating macaque (Macaca fascicularis).
Q52363995In vivo genome editing thrives with diversified CRISPR technologies.
Q90339315Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands
Q91290944NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer
Q93089858TYR Gene in Llamas: Polymorphisms and Expression Study in Different Color Phenotypes
Q99417081Teleological Role of L-2-Hydroxyglutarate Dehydrogenase in the Kidney

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