Analysis of novel domain-specific mutations in the zebrafish ndr2/cyclops gene generated using CRISPR-Cas9 RNPs

scientific article published on 01 December 2018

Analysis of novel domain-specific mutations in the zebrafish ndr2/cyclops gene generated using CRISPR-Cas9 RNPs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12041-018-1033-6
P698PubMed publication ID30555080

P50authorAshley N TurnerQ59705598
Anil K ChallaQ59705604
P2093author name stringJames C Davis
Sarah R Glover
Baraa A Hijaz
Riddhi K Patel
Reagan S Andersen
Victoria L Miller
David M Gahan
Ashish S Kaushik
Austin P Walker
Cerissa L Nowell
Ivy E Bookout
John P Gotham
Jordan B Mcgill
Lauren N Brashear
Mia C Rodgers
Samantha D Foster
Yazen A Shihab
Zachariah P Moseley
P2860cites workInduction of the zebrafish ventral brain and floorplate requires cyclops/nodal signallingQ48021528
The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous systemQ48766492
Mechanisms underlying long- and short-range nodal signaling in Zebrafish.Q50730309
Nodal-related signals establish mesendodermal fate and trunk neural identity in zebrafish.Q52168511
Genetic interactions in zebrafish midline development.Q52526562
A temperature-sensitive mutation in the nodal-related gene cyclops reveals that the floor plate is induced during gastrulation in zebrafishQ73471849
I-TASSER server for protein 3D structure predictionQ21284202
Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAsQ21559464
TGF-beta signal transductionQ22003891
I-TASSER: a unified platform for automated protein structure and function predictionQ24605680
Efficient genome editing in zebrafish using a CRISPR-Cas systemQ24610828
Cumulative ligand activity of NODAL mutations and modifiers are linked to human heart defects and holoprosencephalyQ24642861
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial ImmunityQ24669850
LOMETS: a local meta-threading-server for protein structure predictionQ24682449
Functional analysis of the cysteine residues of activin AQ28244034
Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamilyQ28284251
Novel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation PhenotypesQ28552381
DNA targeting specificity of RNA-guided Cas9 nucleasesQ29615793
The transforming growth factor-beta familyQ29615948
The I-TASSER Suite: protein structure and function prediction.Q30370293
A simple strategy for heritable chromosomal deletions in zebrafish via the combinatorial action of targeting nucleasesQ33745521
Nodal signalling in vertebrate development.Q33833716
A structural superfamily of growth factors containing a cystine knot motifQ34061958
Nodal signaling in early vertebrate embryos: themes and variationsQ34101865
The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm.Q34184235
Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst.Q34191577
The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organismsQ34349039
Genetic analysis of chromosomal rearrangements in the cyclops region of the zebrafish genomeQ34602440
Regulation of TGFβ and related signals by precursor processing.Q35089287
Midline signaling in the primordium of the zebrafish anterior central nervous systemQ35090347
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.Q35896845
cyclops encodes a nodal-related factor involved in midline signalingQ36280774
4 Patterning of Body Segments of the Zebrafish EmbryoQ36790084
Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease systemQ37117695
The Drosophila DPP signal is produced by cleavage of its proprotein at evolutionary diversified furin-recognition sitesQ37208940
Site-specific cleavage of BMP4 by furin, PC6, and PC7.Q37447929
Substrate cleavage analysis of furin and related proprotein convertases. A comparative studyQ40643084
Mutations affecting the development of the embryonic zebrafish brainQ47073179
Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetryQ47073917
P4510describes a project that usesCRISPR-Cas methodQ17310682
P433issue5
P921main subjectCRISPRQ412563
Cas9Q16965677
CRISPR-Cas methodQ17310682
P304page(s)1315-1325
P577publication date2018-12-01
P1433published inJournal of GeneticsQ975661
P1476titleAnalysis of novel domain-specific mutations in the zebrafish ndr2/cyclops gene generated using CRISPR-Cas9 RNPs
P478volume97

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cites work (P2860)
Q90239635A method for CRISPR/Cas9 mutation of genes in fathead minnow (Pimephales promelas)
Q64882578Integrating CRISPR-Cas9 Technology into Undergraduate Courses: Perspectives from a National Science Foundation (NSF) Workshop for Undergraduate Faculty, June 2018.
Q90412003Modeling Neuronal Diseases in Zebrafish in the Era of CRISPR

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