Amlexanox Blocks the Interaction between S100A4 and Epidermal Growth Factor and Inhibits Cell Proliferation

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Amlexanox Blocks the Interaction between S100A4 and Epidermal Growth Factor and Inhibits Cell Proliferation is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1161663C
P356DOI10.1371/JOURNAL.PONE.0161663
P8608Fatcat IDrelease_cckohpayrvadlmo6e53ialkrti
P3181OpenCitations bibliographic resource ID3893016
P932PMC publication ID4999211
P698PubMed publication ID27559743

P50authorRuey-Hwang ChouQ60566680
P2093author name stringChin Yu
Ching Chang Cho
P2860cites workDifferential expression of S100A2 and S100A4 during progression of human prostate adenocarcinomaQ78729048
Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animalQ79368389
S100A4 is upregulated in injured myocardium and promotes growth and survival of cardiac myocytesQ80233959
Three distinct anti-allergic drugs, amlexanox, cromolyn and tranilast, bind to S100A12 and S100A13 of the S100 protein familyQ22008832
Epidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 proteinQ24314713
Structural and functional assays of AtTLP18.3 identify its novel acid phosphatase activity in thylakoid lumenQ24614192
Ligand binding assays at equilibrium: validation and interpretationQ24629851
Binding of pEL98 protein, an S100-related calcium-binding protein, to nonmuscle tropomyosinQ24673485
Structure of the soluble methane monooxygenase regulatory protein BQ27618944
The NMR solution structure of human epidermal growth factor (hEGF) at physiological pH and its interactions with suraminQ27665418
The solution structure of human calcium-bound S100A4 mutated at four cysteine lociQ27700152
Refinement of protein structures in explicit solventQ27860639
Intracellular and extracellular roles of S100 proteinsQ28184555
Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interactionQ28208109
S100A13 is involved in the regulation of fibroblast growth factor-1 and p40 synaptotagmin-1 release in vitroQ28280225
Amlexanox reversibly inhibits cell migration and proliferation and induces the Src-dependent disassembly of actin stress fibers in vitroQ28568028
The HADDOCK web server for data-driven biomolecular dockingQ29617755
SHARP2: protein-protein interaction predictions using patch analysis.Q30354186
Tranilast Blocks the Interaction between the Protein S100A11 and Receptor for Advanced Glycation End Products (RAGE) V Domain and Inhibits Cell ProliferationQ31102154
Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1).Q34113420
Review of epidermal growth factor receptor biologyQ34320636
The metastasis promoting protein S100A4 levels associate with disease activity rather than cancer development in patients with idiopathic inflammatory myopathiesQ34560305
Iodine in evolution of salivary glands and in oral healthQ35008249
Human epidermal growth factor: isolation and chemical and biological propertiesQ35075356
The metastasis associated protein S100A4: role in tumour progression and metastasisQ36131038
Interaction of extracellular S100A4 with RAGE prompts prometastatic activation of A375 melanoma cellsQ36797465
Metastasis-inducing S100A4 protein: implication in non-malignant human pathologiesQ37264795
Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibodyQ37605237
Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertensionQ38321973
Expression of MMP-13 is associated with invasion and metastasis of papillary thyroid carcinomaQ39184184
Recurrent deletion of CHD1 in prostate cancer with relevance to cell invasivenessQ39426050
Tumour response to gefitinib is associated with EGF- and gefitinib- but not radiation-modulated EGFR expression.Q39615211
The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806.Q40210597
Nuclear magnetic resonance measurements of slow conformational dynamics in macromoleculesQ40576284
The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factorQ40787009
Non-muscle myosin heavy chain as a possible target for protein encoded by metastasis-related mts-1 geneQ41449150
Metastasis-associated mts1 (S100A4) protein is selectively expressed in white matter astrocytes and is up-regulated after peripheral nerve or dorsal root injuryQ48130394
Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancerQ63966034
Oligomeric forms of the metastasis-related Mts1 (S100A4) protein stimulate neuronal differentiation in cultures of rat hippocampal neuronsQ73038419
Increased expression of S100A4 and its prognostic significance in esophageal squamous cell carcinomaQ73620708
NMR study of the differential contributions of residues of transforming growth factor alpha to association with its receptorQ73699741
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)e0161663
P577publication date2016-01-01
P1433published inPLOS OneQ564954
P1476titleAmlexanox Blocks the Interaction between S100A4 and Epidermal Growth Factor and Inhibits Cell Proliferation
P478volume11

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cites work (P2860)
Q91620971TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis
Q52372117Targeting IκappaB kinases for cancer therapy.

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