Intracellular and extracellular roles of S100 proteins

scientific article (publication date: 15 April 2003)

Intracellular and extracellular roles of S100 proteins is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1002/JEMT.10296
P3181OpenCitations bibliographic resource ID2888251
P698PubMed publication ID12645002

P2093author name stringRosario Donato
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)540-51
P577publication date2003-04-15
P1433published inMicroscopy Research and TechniqueQ59757
P1476titleIntracellular and extracellular roles of S100 proteins
P478volume60

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cites work (P2860)
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Q42450906Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction
Q33683985Large-scale proteomic identification of S100 proteins in breast cancer tissues
Q56992670Longitudinal serum S100β and brain aging in the Lothian Birth Cohort 1936
Q84984868Loss of Arnt (Hif1β) in mouse epidermis triggers dermal angiogenesis, blood vessel dilation and clotting defects
Q36308264Loss of myeloid-related proteins 8 and myeloid-related proteins 14 expression in human esophageal squamous cell carcinoma correlates with poor differentiation.
Q47127034MALDI MSI of MeLiM melanoma: Searching for differences in protein profiles
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Q38009240Macrophage-related diseases of the gut: a pathologist's perspective
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Q33383191Mecp2-null mice provide new neuronal targets for Rett syndrome.
Q28575948Metastasis-associated S100A4 (Mts1) protein is expressed in subpopulations of sensory and autonomic neurons and in Schwann cells of the adult rat
Q44918219Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis.
Q39911288Microglial activation is not equivalent to neuroinflammation in alcohol-induced neurodegeneration: The importance of microglia phenotype
Q42285471Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers
Q38492052Molecular Analysis of Inflammatory Bowel Disease: Clinically Useful Tools for Diagnosis, Response Prediction, and Monitoring of Targeted Therapy
Q47612069Molecular analysis of transitional cell carcinoma using cDNA microarray
Q43768901Molecular basis of S100 proteins interacting with the p53 homologs p63 and p73.
Q34698701Molecular determinants of S100B oligomer formation
Q45124518Molecular evolution of a novel marsupial S100 protein (S100A19) which is expressed at specific stages of mammary gland and gut development
Q42151468Molecular mechanisms of Ca(2+) signaling in neurons induced by the S100A4 protein
Q36456638Molecular pathology of breast apocrine carcinomas: a protein expression signature specific for benign apocrine metaplasia.
Q88956893Multifarious diagnostic possibilities of the S100 protein family: predominantly in pediatrics and neonatology
Q36169181Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family
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Q46302002Neural-activity-dependent release of S100B from astrocytes enhances kainate-induced gamma oscillations in vivo.
Q38162092Neurological damage in MSUD: the role of oxidative stress.
Q51835366Neuronal and glial differentiation during lizard (Gallotia galloti) visual system ontogeny.
Q36102944Neuropsychopharmacological understanding for therapeutic application of morphinans
Q30862375New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis
Q38186720Nonclassically Secreted Regulators of Angiogenesis
Q28286769Novel S100A7 (psoriasin)/S100A15 (koebnerisin) subfamily: highly homologous but distinct in regulation and function
Q28568022Novel interaction of the dopamine D2 receptor and the Ca2+ binding protein S100B: role in D2 receptor function
Q42128457Novel interactions of the TRTK12 peptide with S100 protein family members: specificity and thermodynamic characterization
Q33651153Nuclear S100A7 is associated with poor prognosis in head and neck cancer.
Q35905318Nutritional Immunity: S100 Proteins at the Host-Pathogen Interface.
Q38105784Opposing functions of psoriasin (S100A7) and koebnerisin (S100A15) in epithelial carcinogenesis.
Q54405936Osteopontin--an important downstream effector of S100A4-mediated invasion and metastasis.
Q34578962Overexpression of S100A4 as a biomarker of metastasis and recurrence in oral squamous cell carcinoma
Q30984031Overexpression of S100A4 in human cancer cell lines resistant to methotrexate
Q37399800Oxidative modifications of S100 proteins: functional regulation by redox
Q38792223PARP1 enhances lung adenocarcinoma metastasis by novel mechanisms independent of DNA repair
Q40458081Peptide mimetic of the S100A4 protein modulates peripheral nerve regeneration and attenuates the progression of neuropathy in myelin protein P0 null mice.
Q36499886Peripheral blood gene expression profiling for cardiovascular disease assessment
Q28305819Peripheral nerve regeneration using autologous porcine skin-derived mesenchymal stem cells
Q38211488Pharmacology of intra-articular triamcinolone
Q92519199Point-of-Care Surface Plasmon Resonance Biosensor for Stroke Biomarkers NT-proBNP and S100β Using a Functionalized Gold Chip with Specific Antibody
Q48824406Postnatal developmental profile of neurons and glia in motor nuclei of the brainstem and spinal cord, and its comparison with organotypic slice cultures
Q38812245Pro-neurogenic effect of β-asarone on RSC96 Schwann cells in vitro.
Q57976328Probing the interaction of distamycin A with S100β: the “unexpected” ability of S100β to bind to DNA-binding ligands
Q33296143Profiling of apoptotic changes in human breast cancer cells using SELDI-TOF mass spectrometry
Q50543875Prognostic impact of S100A9 overexpression in non-small cell lung cancer.
Q48089252Prognostic significance of S100A4-expression and subcellular localization in early-stage breast cancer
Q36425962Prognostic significance of different immunohistochemical S100A2 protein expression patterns in patients with operable nonsmall cell lung carcinoma
Q33783947Proinflammatory effects of S100A8/A9 via TLR4 and RAGE signaling pathways in BV-2 microglial cells
Q61855549Protein expression patterns associated with advanced stage ovarian cancer
Q33891766Protein signatures for survival and recurrence in metastatic melanoma
Q38080394Protein-phospholipid interactions in nonclassical protein secretion: problem and methods of study.
Q58726328Proteome analysis reveals a role of rainbow trout lymphoid organs during Yersinia ruckeri infection process
Q28071331Proteomic Approaches to Biomarker Discovery in Cutaneous T-Cell Lymphoma
Q42702837Proteomic analysis of purified coronavirus infectious bronchitis virus particles
Q36471128Proteomic analysis reveals the deregulation of inflammation-related proteins in acupuncture-treated rats with asthma onset
Q33255758Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages
Q38448646Proteomic characteristics of circulating microparticles in patients with newly-diagnosed type 2 diabetes
Q37297414Pro‑neurogenic effects of andrographolide on RSC96 Schwann cells in vitro
Q37152947RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation.
Q37274344RAGE and its ligands in bone metabolism.
Q37018247Rat retinal transcriptome: effects of aging and AMD-like retinopathy
Q40020050Reciprocal negative regulation between S100A7/psoriasin and beta-catenin signaling plays an important role in tumor progression of squamous cell carcinoma of oral cavity.
Q34687465Relating form and function of EF-hand calcium binding proteins
Q35606748Release of FGF1 and p40 synaptotagmin 1 correlates with their membrane destabilizing ability
Q34503321Reliable disease biomarkers characterizing and identifying electrohypersensitivity and multiple chemical sensitivity as two etiopathogenic aspects of a unique pathological disorder
Q22252919Retinoids for treatment of Alzheimer's disease
Q51987375Role of Scarf and its binding target proteins in epidermal calcium homeostasis.
Q53276425S-100B in Serum and Urine After Traumatic Head Injury in Children
Q49497885S100 Proteins As an Important Regulator of Macrophage Inflammation.
Q35911792S100 calcium binding proteins and ion channels
Q43245445S100 protein family and its application in clinical practice
Q37650123S100 protein family in human cancer
Q38127260S100 proteins and the skin: a review
Q34337425S100 proteins and their influence on pro-survival pathways in cancer
Q58086680S100 proteins as therapeutic targets
Q35803078S100 proteins in cartilage: role in arthritis
Q90747880S100 proteins in rheumatic diseases
Q24336983S100 proteins interact with the N-terminal domain of MDM2
Q37270778S100-annexin complexes--biology of conditional association
Q28249115S100A1 in cardiovascular health and disease: closing the gap between basic science and clinical therapy
Q39130164S100A10 as a novel biomarker in colorectal cancer
Q41211662S100A11 is a potential prognostic marker for clear cell renal cell carcinoma
Q36325990S100A11, an dual mediator for growth regulation of human keratinocytes
Q90411342S100A12 in Digestive Diseases and Health: A Scoping Review
Q38059248S100A12: a noninvasive marker of inflammation in inflammatory bowel disease
Q21135467S100A14 stimulates cell proliferation and induces cell apoptosis at different concentrations via receptor for advanced glycation end products (RAGE)
Q47849319S100A16 is a prognostic marker for colorectal cancer.
Q64110775S100A16 regulated by Snail promotes the chemoresistance of nonmuscle invasive bladder cancer through the AKT/Bcl-2 pathway
Q24306405S100A16, a novel calcium-binding protein of the EF-hand superfamily
Q28288362S100A1: a multifaceted therapeutic target in cardiovascular disease
Q36801998S100A1: a novel inotropic regulator of cardiac performance. Transition from molecular physiology to pathophysiological relevance
Q33757903S100A1: a regulator of striated muscle sarcoplasmic reticulum Ca2+ handling, sarcomeric, and mitochondrial function
Q52027067S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation.
Q37762477S100A2 in cancerogenesis: a friend or a foe?
Q37620665S100A2 is a BRCA1/p63 coregulated tumour suppressor gene with roles in the regulation of mutant p53 stability
Q37461400S100A2 level changes are related to human periodontitis
Q38215158S100A2 protein and non-small cell lung cancer. The dual role concept.
Q33597019S100A4 and metastasis: a small actor playing many roles
Q57072975S100A4 as a Target of the E3-Ligase Asb2β and Its Effect on Engineered Heart Tissue
Q64256146S100A4 inhibits cell proliferation by interfering with the S100A1-RAGE V domain
Q42955189S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases.
Q37281646S100A4 mediates endometrial cancer invasion and is a target of TGF-beta1 signaling
Q42620108S100A4 protects the myocardium against ischemic stress
Q38338396S100A6 (Calcyclin) is a prostate basal cell marker absent in prostate cancer and its precursors
Q22000741S100A7 and the progression of breast cancer
Q33648661S100A7 promotes lung adenocarcinoma to squamous carcinoma transdifferentiation, and its expression is differentially regulated by the Hippo-YAP pathway in lung cancer cells
Q42225284S100A7 promotes the migration and invasion of osteosarcoma cells via the receptor for advanced glycation end products
Q34412828S100A8 and S100A9 Positive Cells in Colorectal Carcinoma: Clinicopathological Analysis.
Q34700918S100A8 and S100A9 are associated with colorectal carcinoma progression and contribute to colorectal carcinoma cell survival and migration via Wnt/β-catenin pathway
Q46745779S100A8 and S100A9 in human arterial wall. Implications for atherogenesis.
Q39767672S100A8/A9 induces apoptosis and inhibits metastasis of CasKi human cervical cancer cells
Q58707556S100A8/A9 promotes parenchymal damage and renal fibrosis in obstructive nephropathy
Q37629632S100A8/A9: a mediator of severe asthma pathogenesis and morbidity?
Q42483466S100B alters neuronal survival and dendrite extension via RAGE-mediated NF-κB signaling.
Q38160208S100B as a marker for brain damage and blood-brain barrier disruption following exercise
Q92939138S100B as an Antagonist To Interfere with the Interface Area Flanked by S100A11 and RAGE V Domain
Q42548561S100B expression defines a state in which GFAP-expressing cells lose their neural stem cell potential and acquire a more mature developmental stage
Q39141087S100B induces the release of pro-inflammatory cytokines in alveolar type I-like cells.
Q43284484S100B modulates the hemodynamic response to norepinephrine stimulation
Q37051646S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages
Q39404676S100B protein as a possible participant in the brain metastasis of NSCLC.
Q48579828S100B protein related neonatal hypoxia
Q90751059S100B suppression alters polarization of infiltrating myeloid-derived cells in gliomas and inhibits tumor growth
Q45911403S100B-RAGE dependent VEGF secretion by cardiac myocytes induces myofibroblast proliferation.
Q37702852S100B: a multifunctional role in cardiovascular pathophysiology
Q38730429S100B + A1 CELISA: A Novel Potency Assay and Screening Tool for Redifferentiation Stimuli of Human Articular Chondrocytes.
Q35939963S100P dissociates myosin IIA filaments and focal adhesion sites to reduce cell adhesion and enhance cell migration
Q28184570S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE)
Q36933470S100b as a prognostic biomarker in outcome prediction for patients with severe traumatic brain injury
Q36112314S100β Levels in CSF of Nonambulatory Dogs with Intervertebral Disk Disease Treated with Electroacupuncture
Q30273961SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination
Q52338705Secretion of the Phosphorylated Form of S100A9 from Neutrophils Is Essential for the Proinflammatory Functions of Extracellular S100A8/A9.
Q24654691Secretion without Golgi
Q52591318Sepsis associated encephalopathy studied by MRI and cerebral spinal fluid S100B measurement.
Q28079379Serotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson's Disease
Q91615108Serum S100A12 and S100B proteins are independent predictors of the presence and severity of obstructive sleep apnea
Q45023114Serum S100A12 levels are associated with the presence and severity of obstructive sleep apnea syndrome in male patients
Q48437115Serum S100B but not NSE levels are increased in morbidly obese individuals affected by obstructive sleep apnea-hypopnea syndrome
Q50048507Serum levels of psoriasin (S100A7) and koebnerisin (S100A15) as potential markers of atherosclerosis in patients with psoriasis
Q37000724Silencing of S100A4, a metastasis-associated protein, inhibits retinal neovascularization via the downregulation of BDNF in oxygen-induced ischaemic retinopathy
Q27655607Small Molecules Bound to Unique Sites in the Target Protein Binding Cleft of Calcium-Bound S100B As Characterized by Nuclear Magnetic Resonance and X-ray Crystallography
Q64268568Solitary neurofibroma of the palate mimicking mucocele: A rare case report
Q42107446Solution structure and backbone dynamics of Calsensin, an invertebrate neuronal calcium-binding protein
Q51201229Solving the crystal structure of human calcium-free S100Z: the siege and conquer of one of the last S100 family strongholds.
Q97516957Structural Investigation of Epididymal Microvasculature and Its Relation to Telocytes and Immune Cells in Camel
Q24322846Structural and functional insights into RAGE activation by multimeric S100B
Q27665571Structural characterization of human S100A16, a low-affinity calcium binder
Q35592681Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B-RAGE-derived peptide complex
Q27652244Structure of the S100A6 Complex with a Fragment from the C-Terminal Domain of Siah-1 Interacting Protein: A Novel Mode for S100 Protein Target Recognition † ‡
Q37453455Subject-specific increases in serum S-100B distinguish sports-related concussion from sports-related exertion
Q53278207TNF alpha affects the expression of GFAP and S100B: implications for Alzheimer's disease.
Q28259868Targeting S100A1 in heart failure
Q34127542Targeting S100B in Cerebral Ischemia and in Alzheimer's Disease
Q42431159The Calcium-Dependent Interaction of S100B with Its Protein Targets
Q27646625The Effects of CapZ Peptide (TRTK-12) Binding to S100B–Ca2+ as Examined by NMR and X-ray Crystallography
Q37704016The Relationship of Serum S100B Levels with Infarction Size and Clinical Outcome in Acute Ischemic Stroke Patients
Q48244517The Role of Danger Signals in the Pathogenesis and Perpetuation of Critical Illness
Q34897380The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis
Q42151789The S100B/RAGE Axis in Alzheimer's Disease
Q33877008The calcium-dependent interaction between S100B and the mitochondrial AAA ATPase ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A.
Q92887845The contribution of S100B to the glioprotective effects of valproic and arundic acids
Q38979165The danger from within: alarmins in arthritis
Q33851482The danger signal S100B integrates pathogen- and danger-sensing pathways to restrain inflammation
Q36629607The diagnostic and prognostic value of MRP8/MRP14 in intrahepatic cholangiocarcinoma
Q35723493The distribution of immunomodulatory cells in the lungs of patients with idiopathic pulmonary fibrosis
Q30810756The expression of RAGE and EN-RAGE in leprosy
Q26851306The heavy chain has its day: regulation of myosin-II assembly
Q44002553The impact of increased blood lactate on serum S100B and prolactin concentrations in male adult athletes
Q38326185The impact of surgical timing and intervention on outcome in traumatized dogs and cats.
Q36461096The ligand/RAGE axis: lighting the fuse and igniting vascular stress
Q33343721The metastasis-associated protein S100A4 exists in several charged variants suggesting the presence of posttranslational modifications
Q45368362The metastasis-promoting S100A4 protein confers neuroprotection in brain injury
Q36814092The metastasis-promoting protein S100A4 regulates mammary branching morphogenesis
Q40526700The myeloid expressed EF-hand proteins display a diverse pattern of lipid raft association
Q26859392The neuroimmunology of schizophrenia
Q27007680The new insight into the role of antimicrobial proteins-alarmins in the immunopathogenesis of psoriasis
Q34561697The receptor for advanced glycation end products and its ligands: a new inflammatory pathway in lung disease?
Q37800755The relevance of protein-protein interactions for p53 function: the CPE contribution.
Q42234262The role of S100A12 as a systemic marker of inflammation
Q33976905The role of S100A14 in epithelial ovarian tumors.
Q34613001The role of TG2 in regulating S100A4-mediated mammary tumour cell migration
Q36338158The role of glial adenosine receptors in neural resilience and the neurobiology of mood disorders
Q35891644The use of matrix coating assisted by an electric field (MCAEF) to enhance mass spectrometric imaging of human prostate cancer biomarkers
Q21132534Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody
Q41915588Thermodynamic and kinetic analysis of peptides derived from CapZ, NDR, p53, HDM2, and HDM4 binding to human S100B
Q38621771Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site.
Q37692260Transcriptional regulation and functional implication of S100P in cancer
Q28306619Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense
Q42873472Transient receptor potential canonical 3 (TRPC3) mediates thrombin-induced astrocyte activation and upregulates its own expression in cortical astrocytes.
Q35582533Two functional S100A4 monomers are necessary for regulating nonmuscle myosin-IIA and HCT116 cell invasion
Q92058313Ubiquitination of Listeria Virulence Factor InlC Contributes to the Host Response to Infection
Q38044377Update of faecal markers of inflammation in children with cystic fibrosis.
Q35109940Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients.
Q35715722Urinary FSP1 is a biomarker of crescentic GN
Q35022269Various forms of tissue damage and danger signals following hematopoietic stem-cell transplantation
Q42762235Voltammetric detection of S100B protein using His-tagged receptor domains for advanced glycation end products (RAGE) immobilized onto a gold electrode surface
Q54285606[Analysis of the mRNA expression of the S100β protein in adipocytes of patients with diabetes mellitus, type 2].
Q46070291¹H, ¹³C and ¹⁵N resonance assignments of Ca²⁺-bound human S100A15.