| scholarly article | Q13442814 |
| P356 | DOI | 10.1093/PROTEIN/GZQ074 |
| P8608 | Fatcat ID | release_fdz6flonavdttjc6cbhw6llohu |
| P698 | PubMed publication ID | 20952436 |
| P5875 | ResearchGate publication ID | 47449717 |
| P50 | author | Maria R Fernandez-Fernandez | Q64681801 |
| P2093 | author name string | Begoña Sot | |
| P2860 | cites work | ASPP proteins specifically stimulate the apoptotic function of p53 | Q24291844 |
| p53 modulates RPA-dependent and RPA-independent WRN helicase activity | Q24296760 | ||
| Regulation of p53 tetramerization and nuclear export by ARC | Q24304068 | ||
| Interaction of p53 with the human Rad51 protein | Q24309466 | ||
| Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2 | Q24314736 | ||
| 14-3-3 activation of DNA binding of p53 by enhancing its association into tetramers | Q24315405 | ||
| Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes | Q24317228 | ||
| Mechanistic differences in the transcriptional activation of p53 by 14-3-3 isoforms | Q24319736 | ||
| PUMA couples the nuclear and cytoplasmic proapoptotic function of p53 | Q24321694 | ||
| Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine | Q24322674 | ||
| Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 | Q24328775 | ||
| MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway | Q24337839 | ||
| Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53. | Q24533476 | ||
| Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53. | Q24535931 | ||
| General transcriptional coactivator PC4 activates p53 function | Q24607528 | ||
| Regulation of the accumulation and function of p53 by phosphorylation of two residues within the domain that binds to Mdm2. | Q38294763 | ||
| The dimeric structure and the bivalent recognition of H3K4me3 by the tumor suppressor ING4 suggests a mechanism for enhanced targeting of the HBO1 complex to chromatin. | Q39755414 | ||
| Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein | Q39848157 | ||
| S100A6 binds p53 and affects its activity | Q39944401 | ||
| The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity. | Q40412703 | ||
| DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization | Q40960688 | ||
| Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein | Q41121233 | ||
| Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax. | Q41784697 | ||
| Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics | Q41909068 | ||
| Members of the S100 family bind p53 in two distinct ways | Q41943285 | ||
| Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers | Q42285471 | ||
| Human full-length Securin is a natively unfolded protein | Q43057992 | ||
| SnapShot: p53 posttranslational modifications | Q43118019 | ||
| The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo | Q43941701 | ||
| p53 functions in the incorporation step in DNA base excision repair in mouse liver mitochondria | Q47314815 | ||
| Inhibition of p53 transcriptional activity by the S100B calcium-binding protein | Q49236826 | ||
| Role of the C-terminal extension in the interaction of S100A1 with GFAP, tubulin, the S100A1- and S100B-inhibitory peptide, TRTK-12, and a peptide derived from p53, and the S100A1 inhibitory effect on GFAP polymerization. | Q50520466 | ||
| Comparative biophysical characterization of p53 with the pro-apoptotic BAK and the anti-apoptotic BCL-xL. | Q50935470 | ||
| Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2). | Q51151705 | ||
| Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53. | Q51564147 | ||
| Calcium-dependent interaction of S100B with the C-terminal domain of the tumor suppressor p53. | Q51605061 | ||
| Is there a bias in proteome research? | Q52936012 | ||
| Delayed ageing through damage protection by the Arf/p53 pathway | Q57562759 | ||
| The BRCA2 gene product functionally interacts with p53 and RAD51 | Q24650406 | ||
| Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2 | Q24656919 | ||
| Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53 | Q24681065 | ||
| Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex | Q24681633 | ||
| NMR chemical shift and relaxation measurements provide evidence for the coupled folding and binding of the p53 transactivation domain | Q24792064 | ||
| Structure of the negative regulatory domain of p53 bound to S100B(betabeta) | Q27625154 | ||
| Crystal structure of a superstable mutant of human p53 core domain. Insights into the mechanism of rescuing oncogenic mutations | Q27642314 | ||
| In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 | Q27642888 | ||
| DNA damage-induced activation of p53 by the checkpoint kinase Chk2 | Q28138195 | ||
| Intracellular and extracellular roles of S100 proteins | Q28184555 | ||
| Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction | Q28208109 | ||
| Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function | Q28212296 | ||
| No PUMA, no death: implications for p53-dependent apoptosis | Q28213266 | ||
| Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka) | Q28214677 | ||
| Immortalization eliminates a roadblock during cellular reprogramming into iPS cells | Q28254388 | ||
| Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha | Q28267232 | ||
| ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins | Q28273233 | ||
| The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation | Q28280958 | ||
| The S100 family of EF-hand calcium-binding proteins: functions and pathology | Q28284255 | ||
| The interaction of p53 with replication protein A mediates suppression of homologous recombination | Q28288360 | ||
| Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300. | Q28360840 | ||
| Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation | Q28586360 | ||
| Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage | Q28609754 | ||
| The p53-mdm-2 autoregulatory feedback loop | Q28609811 | ||
| Mapping of the p53 and mdm-2 Interaction Domains | Q28609886 | ||
| Binding of natively unfolded HIF-1alpha ODD domain to p53 | Q28910406 | ||
| Mechanism of eukaryotic homologous recombination | Q29547709 | ||
| A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity | Q29614209 | ||
| The Ink4/Arf locus is a barrier for iPS cell reprogramming | Q29614210 | ||
| Linking the p53 tumour suppressor pathway to somatic cell reprogramming | Q29616507 | ||
| Suppression of induced pluripotent stem cell generation by the p53-p21 pathway | Q29619160 | ||
| Modulation of microRNA processing by p53 | Q29620776 | ||
| p53 mutant mice that display early ageing-associated phenotypes | Q29622826 | ||
| Modulation of mammalian life span by the short isoform of p53. | Q30312095 | ||
| TROSY and CRINEPT: NMR with large molecular and supramolecular structures in solution. | Q30327393 | ||
| Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A | Q30446685 | ||
| p53 alterations in human cancer: more questions than answers. | Q36777320 | ||
| Transcription-positive cofactor 4 forms complexes with HSSB (RPA) on single-stranded DNA and influences HSSB-dependent enzymatic synthesis of simian virus 40 DNA. | Q36807289 | ||
| Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53 | Q37077431 | ||
| Biology of HIF-1alpha | Q37079724 | ||
| The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development | Q37332559 | ||
| Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein | Q37332768 | ||
| Control of mitochondrial apoptosis by the Bcl-2 family | Q37385623 | ||
| Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90. | Q37402942 | ||
| Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53. | Q37421120 | ||
| HIF at a glance | Q37429370 | ||
| Cytoplasmic functions of the tumour suppressor p53. | Q37466228 | ||
| Mitochondrial MDM4 (MDMX): an unpredicted role in the p53-mediated intrinsic apoptotic pathway | Q37627089 | ||
| The N-terminal domain of p53 is natively unfolded. | Q30879982 | ||
| NMR techniques used with very large biological macromolecules in solution | Q30986393 | ||
| Molecular mechanism of the interaction between MDM2 and p53. | Q33184867 | ||
| Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR. | Q33198227 | ||
| p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity | Q33696861 | ||
| Calcium and S100B regulation of p53-dependent cell growth arrest and apoptosis | Q33775049 | ||
| Regulation of p53 stability | Q33807793 | ||
| Direct NMR observation of a substrate protein bound to the chaperonin GroEL. | Q33920776 | ||
| Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2. | Q33928616 | ||
| Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor | Q33935212 | ||
| Concerted regulation of wild-type p53 nuclear accumulation and activation by S100B and calcium-dependent protein kinase C. | Q33959840 | ||
| Stress signals utilize multiple pathways to stabilize p53 | Q33963268 | ||
| Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. | Q34011633 | ||
| CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90. | Q34036925 | ||
| Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma | Q34116250 | ||
| The role of tetramerization in p53 function | Q34290217 | ||
| The central region of HDM2 provides a second binding site for p53. | Q34335012 | ||
| Hsp70 interactions with the p53 tumour suppressor protein | Q34353830 | ||
| "Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally | Q34369829 | ||
| Cancer risks in BRCA2 mutation carriers | Q34504452 | ||
| The Hsp90 chaperone machinery | Q34774579 | ||
| Awakening guardian angels: drugging the p53 pathway | Q35014385 | ||
| Inhibiting the p53-MDM2 interaction: an important target for cancer therapy | Q35058579 | ||
| Critical contribution of the MDM2 acidic domain to p53 ubiquitination | Q35107890 | ||
| p53's double life: transactivation-independent repression of homologous recombination. | Q35774503 | ||
| Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes. | Q35787179 | ||
| p53: traffic cop at the crossroads of DNA repair and recombination | Q36028209 | ||
| The role of p53 in hypoxia-induced apoptosis | Q36113108 | ||
| Transcription-independent pro-apoptotic functions of p53. | Q36287009 | ||
| p53 in recombination and repair | Q36423948 | ||
| 14-3-3σ Positively Regulates p53 and Suppresses Tumor Growth | Q36549508 | ||
| Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain. | Q36558058 | ||
| DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX. | Q36732878 | ||
| Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability | Q36753352 | ||
| P433 | issue | 1-2 | |
| P921 | main subject | protein-protein interaction | Q896177 |
| P304 | page(s) | 41-51 | |
| P577 | publication date | 2010-10-15 | |
| P1433 | published in | Protein Engineering Design and Selection | Q15762396 |
| P1476 | title | The relevance of protein-protein interactions for p53 function: the CPE contribution | |
| P478 | volume | 24 |
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| Q47164914 | BTK blocks the inhibitory effects of MDM2 on p53 activity |
| Q48243773 | Characterization of an Hsp90-Independent Interaction between Co-Chaperone p23 and Transcription Factor p53. |
| Q39383957 | Golgi-SNARE GS28 potentiates cisplatin-induced apoptosis by forming GS28-MDM2-p53 complexes and by preventing the ubiquitination and degradation of p53. |
| Q28552225 | Influence of Matrices on 3D-Cultured Prostate Cancer Cells' Drug Response and Expression of Drug-Action Associated Proteins |
| Q58552216 | Low Energy Conformations for S100 Binding Peptide from the Negative Regulatory Domain of p53 |
| Q57174649 | Minimotifs dysfunction is pervasive in neurodegenerative disorders |
| Q91816134 | NMR characterization of solvent accessibility and transient structure in intrinsically disordered proteins |
| Q42591177 | Nuclear Localization Signal and p53 Binding Site in MAP/ERK Kinase Kinase 1 (MEKK1) |
| Q52717506 | Regulation of cellular senescence via the FOXO4-p53 axis. |
| Q58582749 | Structural Basis for the Interaction between p53 Transactivation Domain and the Mediator Subunit MED25 |
| Q38740922 | p53 and its mutants on the slippery road from stemness to carcinogenesis |
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