ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

scientific article published on June 1, 1998

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/542
P953full work available online athttp://www.nature.com/articles/ng0698_175
http://www.nature.com/articles/ng0698_175.pdf
P3181OpenCitations bibliographic resource ID2198301
P698PubMed publication ID9620776

P50authorThanos D HalazonetisQ88944552
P2093author name stringE. S. Stavridi
J. L. Waterman
M. J. Waterman
P2860cites workCancer ResearchQ326097
Mdm2 promotes the rapid degradation of p53Q24322597
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserineQ24322674
A single ataxia telangiectasia gene with a product similar to PI-3 kinaseQ24323579
UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse CellsQ24609948
Regulation of p53 stability by Mdm2Q27860744
p53, the cellular gatekeeper for growth and divisionQ27860990
Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216Q28247771
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2Q28254119
14-3-3sigma is a p53-regulated inhibitor of G2/M progressionQ28276061
The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA bindingQ28639955
The Structural Basis for 14-3-3:Phosphopeptide Binding SpecificityQ29547190
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasiaQ29615437
p53 is required for radiation-induced apoptosis in mouse thymocytesQ29620281
DNA damage induces phosphorylation of the amino terminus of p53Q35199554
Wild-type p53 is a cell cycle checkpoint determinant following irradiationQ37152060
Regulation of the specific DNA binding function of p53Q38324290
p53 transactivation and protein accumulation are independently regulated by UV light in different phases of the cell cycleQ40022281
Apoptosis in cancer therapy: crossing the thresholdQ40694262
Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA.Q40872252
Structural aspects of the p53 protein in relation to gene evolution: a second look.Q41034333
Three distinct signalling responses by murine fibroblasts to genotoxic stressQ42807014
14-3-3 and its possible role in co-ordinating multiple signalling pathwaysQ47986680
14-3-3 protein homologs required for the DNA damage checkpoint in fission yeastQ48080836
Thymocyte apoptosis induced by p53-dependent and independent pathwaysQ54242475
p53 status and the efficacy of cancer therapy in vivoQ72839445
The p53 activation and apoptosis induced by DNA damage are reversibly inhibited by salicylateQ73433534
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)175-8
P577publication date1998-06-01
P1433published inNature GeneticsQ976454
P1476titleATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins
P478volume19

Reverse relations

cites work (P2860)
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Q33632328The PIK-related kinases intercept conventional signaling pathways
Q33771774The cellular response to p53: the decision between life and death
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Q33738458The p53 pathway and apoptosis
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Q38327777The time-dependent serial gene response to Zeocin treatment involves caspase-dependent apoptosis in HeLa cells
Q34786668Transcriptional responses to estrogen and progesterone in mammary gland identify networks regulating p53 activity
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Q34699448Ubiquitin proteasomal pathway mediated degradation of p53 in melanoma
Q64236647Understanding p53 functions through p53 antibodies
Q37649607Unreported intrinsic disorder in proteins: Building connections to the literature on IDPs
Q30868748Utilization of oriented peptide libraries to identify substrate motifs selected by ATM.
Q42800244c-abl is involved in the association of p53 and trk A.
Q35787253cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia
Q33734522p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation.
Q36088355p53 RNA interactions: new clues in an old mystery
Q43583412p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling
Q34388165p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiation
Q91701515p53 modifications: exquisite decorations of the powerful guardian
Q33807807p53 regulation by post-translational modification and nuclear retention in response to diverse stresses
Q36997572p53 regulation upon genotoxic stress: intricacies and complexities
Q77954392p53-Dependent growth arrest and altered p53-immunoreactivity following metabolic labelling with 32P ortho-phosphate in human fibroblasts
Q74083357p53-dependent apoptosis is regulated by a C-terminally alternatively spliced form of murine p53
Q34305233p53-dependent apoptosis pathways.
Q36028209p53: traffic cop at the crossroads of DNA repair and recombination

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