Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer's Disease: Studies in an S100B Overexpressing Mouse Model

scientific article published on August 22, 2010

Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer's Disease: Studies in an S100B Overexpressing Mouse Model is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2010/153657
P953full work available at URLhttps://downloads.hindawi.com/archive/2010/153657.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20827311/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20827311/pdf/?tool=EBI
https://europepmc.org/articles/PMC2933893
http://downloads.hindawi.com/archive/2010/153657.pdf
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P932PMC publication ID2933893
P698PubMed publication ID20827311
P5875ResearchGate publication ID46181786

P2093author name stringLee A. Shapiro
Patricia M. Whitaker-Azmitia
Lynn A. Bialowas-McGoey
P2860cites workPhysiology & BehaviorQ3618986
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The serum S100B concentration is age dependentQ74171237
Neurotrophic factor S100 beta in major depressionQ74322174
S-100B is increased in melancholic but not in non-melancholic major depressionQ74452780
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Annexin VI binds S100A1 and S100B and blocks the ability of S100A1 and S100B to inhibit desmin and GFAP assemblies into intermediate filamentsQ28293428
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Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer diseaseQ34309107
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The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's diseaseQ34469528
Neurotrophic protein S100 beta stimulates glial cell proliferationQ34886016
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Neurite extension and neuronal survival activities of recombinant S100 beta proteins that differ in the content and position of cysteine residuesQ36222093
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S100beta induction of the proinflammatory cytokine interleukin-6 in neuronsQ37332541
Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's diseaseQ37480839
Purification and characterization of a neurite extension factor from bovine brainQ37553120
S100 beta induces apoptotic cell death in cultured astrocytes via a nitric oxide-dependent pathwayQ48891481
Stimulation of astroglial 5-HT1A receptors releases the serotonergic growth factor, protein S-100, and alters astroglial morphologyQ48895328
Memory and the effect of cold shock in the water maze in S100 beta transgenic miceQ48952450
S-100B but not NGF, EGF, insulin or calmodulin is a CNS serotonergic growth factorQ48969102
Vitamin E increases S100B-mediated microglial activation in an S100B-overexpressing mouse model of pathological agingQ49047427
S100B/RAGE-dependent activation of microglia via NF-kappaB and AP-1 Co-regulation of COX-2 expression by S100B, IL-1beta and TNF-alphaQ49124580
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Serotonin (5-HT) in brains of adult patients with Down syndrome.Q52171088
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S100 beta protein expression in Alzheimer disease: potential role in the pathogenesis of neuritic plaques.Q53203931
Effects of S100A1 and S100B on microtubule stability. An in vitro study using triton-cytoskeletons from astrocyte and myoblast cell lines.Q55475215
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S-100 in the central nervous system of rat, rabbit and guinea pig during postnatal developmentQ40755477
Analysis of S100A1 expression during skeletal muscle and neuronal cell differentiationQ41338705
S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells.Q41863070
Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's diseaseQ42452339
S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA.Q42598364
The S-100 protein causes an increase of intracellular calcium and death of PC12 cellsQ42810541
Correlation of astrocytic S100 beta expression with dystrophic neurites in amyloid plaques of Alzheimer's disease.Q42877912
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Increased S100 beta neurotrophic activity in Alzheimer's disease temporal lobeQ44370291
Transient expression of S-100β immunostaining in developing thalamus and somatosensory cortex of ratQ44403294
Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacksQ44515041
Harm avoidance, anxiety, and response to novelty in the adolescent S-100beta transgenic mouse: role of serotonin and relevance to Down syndromeQ44531001
Both aging and chronic fluoxetine increase S100B content in the mouse hippocampusQ44576804
Neuropathological study of the dorsal raphe nuclei in late-life depression and Alzheimer's disease with and without depressionQ44915202
Receptor for advanced glycation endproduct (RAGE)-mediated nuclear factor-kappaB activation in vasculitic neuropathyQ44916068
Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanismQ45188778
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Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats.Q45941590
Enhanced susceptibility of S-100B transgenic mice to neuroinflammation and neuronal dysfunction induced by intracerebroventricular infusion of human beta-amyloidQ46421892
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Increased clusterin expression in old but not young adult S100B transgenic mice: evidence of neuropathological aging in a model of Down SyndromeQ47652990
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Microglial and astrocytic cell responses in the rat hippocampus after an intracerebroventricular kainic acid injectionQ48281139
Characterization of social behaviors and oxytocinergic neurons in the S-100β overexpressing mouse model of Down SyndromeQ48313047
Clusterin (apolipoprotein J) protein levels are increased in hippocampus and in frontal cortex in Alzheimer's diseaseQ48313613
Cell-specific expression of high levels of human S100 beta in transgenic mouse brain is dependent on gene dosageQ48413490
Cerebrospinal fluid S100B correlates with brain atrophy in Alzheimer's diseaseQ48417985
S-100 beta and insulin-like growth factor-II differentially regulate growth of developing serotonin and dopamine neurons in vitroQ48427378
S100B is increased in mood disorders and may be reduced by antidepressive treatmentQ48479208
Cytokine regulation of human microglial cell IL-8 productionQ48532242
Arundic Acid ameliorates cerebral amyloidosis and gliosis in Alzheimer transgenic miceQ48533154
Transgenic mice overexpressing the neurotrophic factor S-100 beta show neuronal cytoskeletal and behavioral signs of altered aging processes: implications for Alzheimer's disease and Down's syndromeQ48558144
A study of the serotonin transporter in the prefrontal cortex in late-life depression and Alzheimer's disease with and without depressionQ48566499
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Serotonin depletion during synaptogenesis leads to decreased synaptic density and learning deficits in the adult rat: a possible model of neurodevelopmental disorders with cognitive deficitsQ48682281
Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's diseaseQ48771318
Increased S100B blood levels in unmedicated and treated schizophrenic patients are correlated with negative symptomatologyQ48819891
Nerve growth factor inhibits apoptosis induced by S-100 binding in neuronal PC12 cellsQ48825446
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectneuronitisQ17157137
Alzheimer's diseaseQ11081
Down syndromeQ47715
overexpressionQ61643320
P304page(s)797-809
P577publication date2010-08-22
P1433published inCardiovascular Psychiatry and NeurologyQ26842033
P1476titleEffects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer's Disease: Studies in an S100B Overexpressing Mouse Model
P478volume2010

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cites work (P2860)
Q57808520Altered S100 Calcium-Binding Protein B and Matrix Metallopeptidase 9 as Biomarkers of Mesial Temporal Lobe Epilepsy with Hippocampus Sclerosis
Q48110984Comparative proteome analysis for identification of differentially abundant proteins in SIDS.
Q37620620Early and sustained altered expression of aging-related genes in young 3xTg-AD mice
Q47287966Effect of Early-Life Fluoxetine on Anxiety-Like Behaviors in BDNF Val66Met Mice
Q48202410Elevated levels of cerebrospinal fluid neuron-specific enolase (NSE), but not S100B in major depressive disorder
Q37903240Nanoparticles and colloids as contributing factors in neurodegenerative disease
Q38857132Post-natal Deletion of Neuronal cAMP Responsive-Element Binding (CREB)-1 Promotes Pro-inflammatory Changes in the Mouse Hippocampus.

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