S100A1: a multifaceted therapeutic target in cardiovascular disease

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S100A1: a multifaceted therapeutic target in cardiovascular disease is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1010614909
P356DOI10.1007/S12265-010-9211-9
P8608Fatcat IDrelease_5g37366y4vg4bnddryswmgq7zu
P3181OpenCitations bibliographic resource ID3299815
P932PMC publication ID2933808
P698PubMed publication ID20645037
P5875ResearchGate publication ID45276166

P50authorHugo A. KatusQ27929168
P2093author name stringDavid Rohde
Mirko Voelkers
Patrick Most
Julia Ritterhoff
Thomas G Parker
P2860cites workHeart Disease and Stroke Statistics--2010 Update: A Report From the American Heart AssociationQ22306345
Ca2+ -dependent interaction of S100A1 with the sarcoplasmic reticulum Ca2+ -ATPase2a and phospholamban in the human heartQ24305007
S100A1: a regulator of myocardial contractilityQ24555086
Three-dimensional solution structure of the calcium-signaling protein apo-S100A1 as determined by NMRQ27637285
Structural and motional changes induced in apo-S100A1 protein by the disulfide formation between its Cys 85 residue and beta-mercaptoethanolQ27649355
Functional roles of S100 proteins, calcium-binding proteins of the EF-hand typeQ28139003
Transcriptional regulation of S100A1 and expression during mouse heart developmentQ28139632
S100A1, a new marker for acute myocardial ischemiaQ28142557
Right ventricular upregulation of the Ca(2+) binding protein S100A1 in chronic pulmonary hypertensionQ28143987
Intracellular and extracellular roles of S100 proteinsQ28184555
Titin-actin interaction in mouse myocardium: passive tension modulation and its regulation by calcium/S100A1Q28188329
S100A12 (EN-RAGE) in monitoring Kawasaki diseaseQ28191511
Understanding ATP synthesis: structure and mechanism of the F1-ATPase (Review)Q28203942
Extracellular S100A1 protein inhibits apoptosis in ventricular cardiomyocytes via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2)Q28205358
Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performanceQ28207738
Impaired cardiac contractility response to hemodynamic stress in S100A1-deficient miceQ28209366
The small EF-hand Ca2+ binding protein S100A1 increases contractility and Ca2+ cycling in rat cardiac myocytesQ28217246
Ultrastructural distribution of the S100A1 Ca2+-binding protein in the human heartQ28217514
S100ao (alpha alpha) protein is mainly located in the heart and striated musclesQ28235967
Interaction of S100A1 with the Ca2+ release channel (ryanodine receptor) of skeletal muscleQ28249011
S100A1 in cardiovascular health and disease: closing the gap between basic science and clinical therapyQ28249115
S100A1 gene transfer: a strategy to strengthen engineered cardiac graftsQ28256042
S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytesQ28258841
Cardiac S100A1 protein levels determine contractile performance and propensity toward heart failure after myocardial infarctionQ28261916
S100A1: Structure, Function, and Therapeutic PotentialQ28263662
S100A1 gene therapy preserves in vivo cardiac function after myocardial infarctionQ28272699
Distinct subcellular localization of calcium binding S100 proteins in human smooth muscle cells and their relocation in response to rises in intracellular calciumQ28275090
S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end productsQ28276090
S100A1 increases the gain of excitation-contraction coupling in isolated rabbit ventricular cardiomyocytesQ28277947
S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature)Q28279641
Titin-isoform dependence of titin-actin interaction and its regulation by S100A1/Ca2+ in skinned myocardiumQ28280473
Hydrophobic residues in the C-terminal region of S100A1 are essential for target protein binding but not for dimerizationQ28287795
Altered expression of the Ca(2+)-binding protein S100A1 in human cardiomyopathyQ28295279
Cardiac adenoviral S100A1 gene delivery rescues failing myocardiumQ28296403
Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescueQ28300082
Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein familyQ28301899
Distinct subcellular location of the Ca2+-binding protein S100A1 differentially modulates Ca2+-cycling in ventricular rat cardiomyocytesQ28302811
The three-dimensional solution structure of Ca(2+)-bound S100A1 as determined by NMR spectroscopyQ28575112
Augmentation of Cav1 channel current and action potential duration after uptake of S100A1 in sympathetic ganglion neuronsQ28580012
More ‘malignant’ than cancer? Five-year survival following a first admission for heart failureQ57396381
Ca2+ /S100 regulation of giant protein kinasesQ57838277
S-100ao protein in serum during acute myocardial infarctionQ68748465
S100a0 (alpha alpha) protein: distribution in muscle tissues of various animals and purification from human pectoral muscleQ68866362
Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activationQ73010823
S100A4 is upregulated in injured myocardium and promotes growth and survival of cardiac myocytesQ80233959
Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cellsQ81144246
S100B expression modulates left ventricular remodeling after myocardial infarction in miceQ81378185
The ischemic rat heart releases S100BQ81793588
S100A1: a calcium-modulating inotropic prototype for future clinical heart failure therapyQ84631543
Redox modifications of the C-terminal cysteine residue cause structural changes in S100A1 and S100B proteins.Q30349807
NO/redox disequilibrium in the failing heart and cardiovascular systemQ30475784
Modular motif, structural folds and affinity profiles of the PEVK segment of human fetal skeletal muscle titinQ31577644
Immunocytochemical localization of S100A1 in mitochondria on cryosections of the rat heartQ33292136
S100A1: a regulator of striated muscle sarcoplasmic reticulum Ca2+ handling, sarcomeric, and mitochondrial functionQ33757903
beta-adrenergic receptor blockade in chronic heart failureQ33831388
S100 proteins: structure, functions and pathologyQ34625714
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of CardiologyQ34830023
Cardiac energy metabolism homeostasis: role of cytosolic calciumQ34977128
Molecular mechanisms of S100-target protein interactionsQ35088392
What is the role of beta-adrenergic signaling in heart failure?Q35582718
Calcium-dependent and -independent interactions of the S100 protein family.Q36472950
S100A1: a novel inotropic regulator of cardiac performance. Transition from molecular physiology to pathophysiological relevanceQ36801998
A review of the S100 proteins in cancerQ36848759
Targeting myocardial beta-adrenergic receptor signaling and calcium cycling for heart failure gene therapyQ36865884
Treatment strategies for peripheral artery diseaseQ37519704
S100A1: a pluripotent regulator of cardiac and vascular functionQ37729863
S100-mediated signal transduction in the nervous system and neurological diseases.Q40371571
Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end productsQ42414162
Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarctionQ42450906
Endothelial S100A1 modulates vascular function via nitric oxide.Q42525001
Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytesQ42738033
Isoproterenol-induced myocardial injury resulting in altered S100A4 and S100A11 protein expression in the rat.Q43504846
Regulation of the S100B gene by alpha 1-adrenergic stimulation in cardiac myocytesQ44185618
S100A6 is a negative regulator of the induction of cardiac genes by trophic stimuli in cultured rat myocytesQ45225467
Affinity of S100A1 protein for calcium increases dramatically upon glutathionylationQ46483015
A soluble protein characteristic of the nervous systemQ47721048
S100a0 (alpha alpha) protein in cardiac muscle. Isolation from human cardiac muscle and ultrastructural localizationQ48122912
The brain protein S-100ab induces apoptosis in PC12 cellsQ48136732
Isolation of a rat S100α cDNA and distribution of its mRNA in rat tissuesQ48217089
Rapid desensitization of PC12 cells stimulated with high concentrations of extracellular S100.Q48238883
Expression of members of the S100 Ca2+-binding protein family in guinea-pig smooth muscleQ48410276
Interaction of isoforms of S100 protein with smooth muscle caldesmonQ48518541
S100A1 gene transfer in myocardium.Q50708011
Increased serum levels and expression of S100A8/A9 complex in infiltrated neutrophils in atherosclerotic plaque of unstable angina.Q53495274
Co-expression/co-location of S100 proteins (S100B, S100A1 and S100A2) and protein kinase C (PKC-beta, -eta and -zeta) in a rat model of cerebral basilar artery vasospasm.Q54631849
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectgene therapyQ213901
cardiovascular diseaseQ389735
transport proteinQ2111029
nerve tissue proteinQ6996861
biomedical investigative techniqueQ66648976
cardiovascular agentQ50429907
P304page(s)525-37
P577publication date2010-10-01
P1433published inJournal of Cardiovascular Translational ResearchQ6294906
P1476titleS100A1: a multifaceted therapeutic target in cardiovascular disease
P478volume3

Reverse relations

cites work (P2860)
Q41844120An efficient expression and purification strategy for the production of S100 proteins in Escherichia coli
Q88674963Association between serum S100A1 level and Global Registry of Acute Coronary Events score in patients with non-ST-segment elevation acute coronary syndrome
Q37965045Cardiac gene therapy: from concept to reality
Q38506250Cardiomyocytes, endothelial cells and cardiac fibroblasts: S100A1's triple action in cardiovascular pathophysiology
Q48498411Functional evidence for an active role of B-type natriuretic peptide in cardiac remodelling and pro-arrhythmogenicity.
Q37001259Functions of S100 proteins.
Q36617570Gene targeting in ischemic heart disease and failure: translational and clinical studies
Q36698991Gene transfer for congestive heart failure: update 2013.
Q37683440Induction of microRNA-138 by pro-inflammatory cytokines causes endothelial cell dysfunction
Q42390071Inhibition of cardiac CaMKII to cure heart failure: step by step towards translation?
Q97529094Molecular Basis of S100A1 Activation and Target Regulation Within Physiological Cytosolic Ca2+ Levels
Q36678598Molecular Basis of S100A1 Activation at Saturating and Subsaturating Calcium Concentrations
Q36175406Myocardial infarction in a patient with left ventricular noncompaction: a case report.
Q35930186Neoinnervation and neovascularization of acellular pericardial-derived scaffolds in myocardial infarcts.
Q42128457Novel interactions of the TRTK12 peptide with S100 protein family members: specificity and thermodynamic characterization
Q27673395Post-translational S-Nitrosylation Is an Endogenous Factor Fine Tuning the Properties of Human S100A1 Protein
Q35603727Role of S100A1 in hypoxia-induced inflammatory response in cardiomyocytes via TLR4/ROS/NF-κB pathway
Q35911792S100 calcium binding proteins and ion channels
Q35206368S100 proteins in cancer
Q35879854S100A1 (S100 calcium binding protein A1)
Q36756998S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 Dysfunction.
Q39031292S100A1 and S100B: Calcium Sensors at the Cross-Roads of Multiple Chondrogenic Pathways
Q28240188S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4
Q64256146S100A4 inhibits cell proliferation by interfering with the S100A1-RAGE V domain
Q50000872S100B as an antagonist to block the interaction between S100A1 and the RAGE V domain.
Q28259868Targeting S100A1 in heart failure
Q26822507Use of isosorbide dinitrate and hydralazine in African-Americans with heart failure 9 years after the African-American Heart Failure Trial

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