S100 proteins in cancer

scientific article

S100 proteins in cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1038/NRC3893
P932PMC publication ID4369764
P698PubMed publication ID25614008
P5875ResearchGate publication ID271330867

P2093author name stringDanna B Zimmer
Anne R Bresnick
David J Weber
P2860cites workSelective expression of S100A11 in lung cancer and its role in regulating proliferation of adenocarcinomas cellsQ84809412
Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibodyQ21132534
S100A9 interaction with TLR4 promotes tumor growthQ21134707
Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamidesQ21145828
S100A7 and the progression of breast cancerQ22000741
Psoriasin (S100A7) expression and invasive breast cancerQ22010926
Psoriasin expression in mammary epithelial cells in vitro and in vivoQ24292122
A putative role for psoriasin in breast tumor progressionQ24298889
S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathwaysQ24598566
Comprehensive molecular portraits of human breast tumoursQ24630844
Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 proteinQ24641894
Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cellsQ24658240
S100A7 (psoriasin) expression is associated with aggressive features and alteration of Jab1 in ductal carcinoma in situ of the breastQ24805971
Common gene pathways and families altered by DNA methylation in breast and prostate cancersQ27025145
Frequent polymorphic variations but rare tumour specific mutations of the S100A2 on 1q21 in non-small cell lung cancerQ81701022
Plasminogen receptor S100A10 is essential for the migration of tumor-promoting macrophages into tumor sitesQ82285506
Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancerQ82606605
Lung metastasis fails in MMTV-PyMT oncomice lacking S100A4 due to a T-cell deficiency in primary tumorsQ82657236
Lost in migrationQ83155814
Hypoxia upregulates ovarian cancer invasiveness via the binding of HIF-1α to a hypoxia-induced, methylation-free hypoxia response element of S100A4 geneQ83353256
Review of S100A9 biology and its role in cancerQ36896567
Premetastatic soil and prevention of breast cancer brain metastasisQ36943888
CD166/ALCAM mediates proinflammatory effects of S100B in delayed type hypersensitivityQ36948770
Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complexQ37000587
Functions of S100 proteins.Q37001259
In vivo screening of S100B inhibitors for melanoma therapyQ37033010
S100B promotes glioma growth through chemoattraction of myeloid-derived macrophagesQ37051646
A colorectal cancer classification system that associates cellular phenotype and responses to therapyQ37175913
Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding proteinQ37332768
Linking folding and bindingQ37373866
Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic targetQ37389009
Solution structure of S100A1 bound to the CapZ peptide (TRTK12).Q37401737
Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growthQ37502777
Designing and developing S100P inhibitor 5-methyl cromolyn for pancreatic cancer therapyQ37665005
Wnt up your mind - intervention strategies for S100A4-induced metastasis in colon cancerQ37679562
Transcriptional regulation and functional implication of S100P in cancerQ37692260
Oxidative modifications of DAMPs suppress inflammation: the case for S100A8 and S100A9.Q37797506
The importance of Ca2+/Zn2+ signaling S100 proteins and RAGE in translational medicineQ37881725
Update on the epidermal differentiation complex.Q37971574
Molecular genetics of prostate cancer: emerging appreciation of genetic complexityQ37972706
From genes to drugs: targeted strategies for melanomaQ37999967
Application of molecular techniques in the diagnosis, prognosis and management of patients with colorectal cancer: a practical approachQ38015538
Joining S100 proteins and migration: for better or for worse, in sickness and in health.Q38118075
Inflammation and skin cancer: old pals telling new storiesQ38165688
Functional evidence implicating S100P in prostate cancer progressionQ38291350
Localisation by in situ hybridisation of S100A4 (p9Ka) mRNA in primary human breast tumour specimens.Q38313886
S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasisQ38320167
Hypoxia and HIF-1 increase S100A8 and S100A9 expression in prostate cancerQ38326104
Glucocorticoid receptor-mediated transcriptional activation of S100P gene coding for cancer-related calcium-binding protein.Q38333462
Profiling of chromosomal changes in potentially malignant and malignant oral mucosal lesions from South and South-East Asia using array-comparative genomic hybridizationQ38391163
S100A6 as a potential serum prognostic biomarker and therapeutic target in gastric cancerQ39007287
Metastasis-associated protein S100A4 induces a network of inflammatory cytokines that activate stromal cells to acquire pro-tumorigenic propertiesQ39064628
RAGE-binding S100A8/A9 promotes the migration and invasion of human breast cancer cells through actin polymerization and epithelial-mesenchymal transitionQ39068126
Impact of S100A8/A9 expression on prostate cancer progression in vitro and in vivoQ39079681
S100A11 overexpression contributes to the malignant phenotype of papillary thyroid carcinoma.Q39113324
Comparative proteomics of glioma stem cells and differentiated tumor cells identifies S100A9 as a potential therapeutic targetQ39128660
RNA interference suppression of A100A4 reduces the growth and metastatic phenotype of human renal cancer cells via NF-kB-dependent MMP-2 and bcl-2 pathwayQ39129170
Anti-S100A4 antibody suppresses metastasis formation by blocking stroma cell invasion.Q39212411
Prostaglandin E2 stimulates S100A8 expression by activating protein kinase A and CCAAT/enhancer-binding-protein-beta in prostate cancer cellsQ39326250
S100P, a potential novel prognostic marker in colorectal cancerQ39354821
Knockdown of S100A4 decreases tumorigenesis and metastasis in osteosarcoma cells by repression of matrix metalloproteinase-9.Q39403731
In vivo antitumor effect of cromolyn in PEGylated liposomes for pancreatic cancerQ39464914
Stable knockdown of S100A4 suppresses cell migration and metastasis of osteosarcoma.Q39584443
The epithelial-mesenchymal transition mediator S100A4 maintains cancer-initiating cells in head and neck cancersQ39618327
Metastasis-inducing S100A4 and RANTES cooperate in promoting tumor progression in miceQ39707595
RAGE and S100 protein transcription levels are highly variable in human melanoma tumors and cellsQ39749194
Short hairpin RNA-mediated inhibition of S100A4 promotes apoptosis and suppresses proliferation of BGC823 gastric cancer cells in vitro and in vivoQ39769588
S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis.Q39814040
S100A8 and S100A9 overexpression is associated with poor pathological parameters in invasive ductal carcinoma of the breastQ39974430
Adjuvant therapy with small hairpin RNA interference prevents non-small cell lung cancer metastasis development in miceQ40002529
Reciprocal negative regulation between S100A7/psoriasin and beta-catenin signaling plays an important role in tumor progression of squamous cell carcinoma of oral cavity.Q40020050
Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profilingQ40085596
Modified expression of Mts1/S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo.Q40183154
S100A2 induces metastasis in non-small cell lung cancerQ45398473
Calcium-binding properties of wild-type and EF-hand mutants of S100B in the presence and absence of a peptide derived from the C-terminal negative regulatory domain of p53.Q46480214
Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activityQ47662103
A soluble protein characteristic of the nervous systemQ47721048
Expression of antisense RNA to S100A4 gene encoding an S100-related calcium-binding protein suppresses metastatic potential of high-metastatic Lewis lung carcinoma cellsQ48054885
Inhibition of p53 transcriptional activity by the S100B calcium-binding proteinQ49236826
S100A3 suppression inhibits in vitro and in vivo tumor growth and invasion of human castration-resistant prostate cancer cells.Q53248783
Expression of S100 proteins in normal human tissues and common cancers using tissue microarrays: S100A6, S100A8, S100A9 and S100A11 are all overexpressed in common cancers.Q53360582
Ribonucleic acid interference targeting S100A4 (Mts1) suppresses tumor growth and metastasis of anaplastic thyroid carcinoma in a mouse model.Q53631324
S100P calcium-binding protein expression is associated with high-risk proliferative lesions of the breast.Q53645627
S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells.Q54290587
Reversal of the in vivo metastatic phenotype of human tumor cells by an anti-CAPL (mts1) ribozymeQ58048723
Mutually antagonistic actions of S100A4 and S100A1 on normal and metastatic phenotypesQ58377503
A rapid separation of S100 subunits by high performance liquid chromatography: the subunit compositions of S100 proteinsQ71221320
Effect of mts1 (S100A4) expression on the progression of human breast cancer cellsQ71574517
Metastasis of mammary carcinomas in GRS/A hybrid mice transgenic for the mts1 geneQ71733492
Radiation therapy for malignant melanomaQ71931107
Aberrant regulation and function of wild-type p53 in radioresistant melanoma cellsQ73010028
A heterocomplex formed by the calcium-binding proteins MRP8 (S100A8) and MRP14 (S100A9) binds unsaturated fatty acids with high affinityQ73182618
Prognostic significance of the metastasis-inducing protein S100A4 (p9Ka) in human breast cancerQ73629119
S100B protein in clinical diagnostics: assay specificityQ75227914
Urinary excretion of epidermal-type fatty acid-binding protein and S100A7 protein in patients with cutaneous melanomaQ78595168
Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100BQ79161452
Expression of S100A4 by a variety of cell types present in the tumor microenvironment of human breast cancerQ80471059
Profiling early head and neck cancerQ81348453
Origins of the tumor microenvironment: quantitative assessment of adipose-derived and bone marrow-derived stromaQ27309626
Structure of Ca 2+ -Bound S100A4 and Its Interaction with Peptides Derived from Nonmuscle Myosin-IIA †Q27650317
Divalent Metal Ion Complexes of S100B in the Absence and Presence of PentamidineQ27651040
Fragmenting the S100B-p53 interaction: combined virtual/biophysical screening approaches to identify ligandsQ27658965
Molecular level interactions of S100A13 with amlexanox: inhibitor for formation of the multiprotein complex in the nonclassical pathway of acidic fibroblast growth factorQ27660013
Phenothiazines inhibit S100A4 function by inducing protein oligomerizationQ27660911
S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE)Q28184570
Psoriasin interacts with Jab1 and influences breast cancer progressionQ28191754
Characterization of the metastasis-associated protein, S100A4. Roles of calcium binding and dimerization in cellular localization and interaction with myosinQ28205156
Effect of Mts1 on the structure and activity of nonmuscle myosin IIQ28257003
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasisQ28275735
Differential expression of S100 protein subtypes in malignant melanoma, and benign and malignant peripheral nerve sheath tumorsQ28283566
Novel S100A7 (psoriasin)/S100A15 (koebnerisin) subfamily: highly homologous but distinct in regulation and functionQ28286769
S100A1: a multifaceted therapeutic target in cardiovascular diseaseQ28288362
The S100 protein family: history, function, and expressionQ28293937
A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4Q28306743
Common interactions between S100A4 and S100A9 defined by a novel chemical probeQ28487759
The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phaseQ28507440
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through METQ29618139
S100A4 regulates macrophage chemotaxisQ30495765
A biosensor of S100A4 metastasis factor activation: inhibitor screening and cellular activation dynamicsQ33312065
S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formationQ33322536
Protein profiling of human breast tumor cells identifies novel biomarkers associated with molecular subtypesQ33329750
Expression patterns of S100 proteins in melanocytes and melanocytic lesionsQ33466720
Myeloid-derived suppressor cells in the development of lung cancerQ33555717
Complex formation between S100B protein and the p90 ribosomal S6 kinase (RSK) in malignant melanoma is calcium-dependent and inhibits extracellular signal-regulated kinase (ERK)-mediated phosphorylation of RSKQ33556286
S100P antibody-mediated therapy as a new promising strategy for the treatment of pancreatic cancerQ33685170
Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing miceQ33721765
Folding and binding cascades: shifts in energy landscapesQ33723481
Diversity of conformational states and changes within the EF-hand protein superfamilyQ33790634
Differential role of psoriasin (S100A7) in estrogen receptor α positive and negative breast cancer cells occur through actin remodelingQ33804642
Targeting S100P inhibits colon cancer growth and metastasis by Lentivirus-mediated RNA interference and proteomic analysisQ33822378
The effect of pentamidine on melanoma ex vivo.Q33835672
Simultaneous inhibition of key growth pathways in melanoma cells and tumor regression by a designed bidentate constrained helical peptideQ33934743
Cysteine 81 is critical for the interaction of S100A4 and myosin-IIAQ33958590
The calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanomaQ34094678
Sumoylation and Nuclear Translocation of S100A4 Regulate IL-1β-mediated Production of Matrix Metalloproteinase-13Q34181448
Phase II randomized, double-blind, placebo-controlled study of tasquinimod in men with minimally symptomatic metastatic castrate-resistant prostate cancerQ34217642
Psoriasin (S100A7) increases the expression of ROS and VEGF and acts through RAGE to promote endothelial cell proliferationQ34242174
Inhibition of metastasis in a castration resistant prostate cancer model by the quinoline-3-carboxamide tasquinimod (ABR-215050).Q34250496
Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cellsQ34324710
Molecular interface of S100A8 with cytochrome b558 and NADPH oxidase activationQ34341915
PSAPP mice exhibit regionally selective reductions in gliosis and plaque deposition in response to S100B ablation.Q34376145
Covalent small molecule inhibitors of Ca(2+)-bound S100B.Q34414451
Intervening in β-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasisQ34551546
Identification of small-molecule inhibitors of the human S100B-p53 interaction and evaluation of their activity in human melanoma cells.Q34572489
S100P is a novel interaction partner and regulator of IQGAP1Q34606213
The induction of S100p expression by the Prostaglandin E2(PGE2)/EP4 receptor signaling pathway in colon cancer cellsQ34616607
The role of conformational entropy in molecular recognition by calmodulinQ34632794
S100A8/A9 activate key genes and pathways in colon tumor progressionQ34802977
Functional role of S100A14 genetic variants and their association with esophageal squamous cell carcinomaQ34974664
Structure of the S100A4/myosin-IIA complexQ35047058
S100A8 is a novel therapeutic target for anaplastic thyroid carcinomaQ35055025
S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9Q35075493
S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cellsQ35210979
VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonizationQ35229115
APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasisQ35484686
Tumor-suppressive effects of psoriasin (S100A7) are mediated through the β-catenin/T cell factor 4 protein pathway in estrogen receptor-positive breast cancer cellsQ35639956
Effect of cromolyn on S100P interactions with RAGE and pancreatic cancer growth and invasion in mouse modelsQ35702968
Profiling signaling polarity in chemotactic cells.Q35850143
S100 calcium binding proteins and ion channelsQ35911792
Target binding to S100B reduces dynamic properties and increases Ca(2+)-binding affinity for wild type and EF-hand mutant proteinsQ36291452
Design of Inhibitors for S100B.Q36296626
Sulfiredoxin redox-sensitive interaction with S100A4 and non-muscle myosin IIA regulates cancer cell motilityQ36320546
Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.Q36339222
Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathwaysQ36378382
Coupling S100A4 to Rhotekin alters Rho signaling output in breast cancer cells.Q36476504
A CXCL1 paracrine network links cancer chemoresistance and metastasisQ36482032
RAGE signaling sustains inflammation and promotes tumor developmentQ36502858
Cyclooxygenase-2 is involved in S100A2-mediated tumor suppression in squamous cell carcinoma.Q40243783
S100-mediated signal transduction in the nervous system and neurological diseases.Q40371571
The S100A7-c-Jun activation domain binding protein 1 pathway enhances prosurvival pathways in breast cancerQ40402282
Interleukin-6 is a potent inducer of S100P, which is up-regulated in androgen-refractory and metastatic prostate cancerQ40505958
Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction.Q40509580
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad.Q40743083
Transfection of S100A4 produces metastatic variants of an orthotopic model of bladder cancerQ40751670
The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factorQ40787009
Human S100A4 (p9Ka) induces the metastatic phenotype upon benign tumour cellsQ41018525
Differential expression patterns of S100A2, S100A4 and S100A6 during progression of human malignant melanomaQ41093031
Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumoursQ41158050
Non-muscle myosin heavy chain as a possible target for protein encoded by metastasis-related mts-1 geneQ41449150
Induction of the metastatic phenotype by transfection of a benign rat mammary epithelial cell line with the gene for p9Ka, a rat calcium-binding protein, but not with the oncogene EJ-ras-1.Q41562528
Epigenetic regulation of S100 protein expressionQ41810264
Therapeutic safety of high myocardial expression levels of the molecular inotrope S100A1 in a preclinical heart failure modelQ41890749
S100A4 silencing blocks invasive ability of esophageal squamous cell carcinoma cellsQ42092162
Characterization of the Ca2+ -regulated ezrin-S100P interaction and its role in tumor cell migrationQ42149470
S100A14 promotes the growth and metastasis of hepatocellular carcinomaQ42253768
Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction.Q42351969
The Calcium-Dependent Interaction of S100B with Its Protein TargetsQ42431159
The role of S100 genes in breast cancer progressionQ42481244
Evolution of the S100 family of calcium sensor proteinsQ42681277
The S100A4 Oncoprotein Promotes Prostate Tumorigenesis in a Transgenic Mouse Model: Regulating NFκB through the RAGE Receptor.Q42969892
Changes in S100A8 expression in UV-irradiated and aged human skin in vivoQ43873330
Interaction of S100 proteins with the antiallergic drugs, olopatadine, amlexanox, and cromolyn: identification of putative drug binding sites on S100A1 proteinQ43955145
The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis.Q44480772
Psoriasin (S100A7) expression is associated with poor outcome in estrogen receptor-negative invasive breast cancerQ44509716
The Ca2+ sensor S100A1 modulates neuroinflammation, histopathology and Akt activity in the PSAPP Alzheimer's disease mouse modelQ44710510
S100A8 and S100A9-oxidant scavengers in inflammation.Q44967617
Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer.Q45254364
The metastasis-promoting S100A4 protein confers neuroprotection in brain injuryQ45368362
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)96-109
P577publication date2015-02-01
P1433published inNature Reviews CancerQ641657
P1476titleS100 proteins in cancer
P478volume15

Reverse relations

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Q33899239Quantitative proteomics reveal the anti-tumour mechanism of the carbohydrate recognition domain of Galectin-3 in Hepatocellular carcinoma
Q89484239RAGE and Its Ligands: Molecular Interplay Between Glycation, Inflammation, and Hallmarks of Cancer-a Review
Q38964572RAGE: A novel target for breast cancer growth and metastasis
Q64111589Realizing the Clinical Potential of Immunogenic Cell Death in Cancer Chemotherapy and Radiotherapy
Q38700311Reduction in Migratory Phenotype in a Metastasized Breast Cancer Cell Line via Downregulation of S100A4 and GRM3.
Q58721652Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis
Q26776055Regulation of the Intestinal Barrier Function by Host Defense Peptides
Q55610234Regulation of von-Willebrand Factor Secretion from Endothelial Cells by the Annexin A2-S100A10 Complex.
Q38689543Retrospective Proteomic Screening of 100 Breast Cancer Tissues.
Q36909178Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9
Q58576722S100 Proteins in Acute Myeloid Leukemia
Q58086680S100 proteins as therapeutic targets
Q92964700S100 proteins: An emerging cynosure in pregnancy & adverse reproductive outcome
Q39031292S100A1 and S100B: Calcium Sensors at the Cross-Roads of Multiple Chondrogenic Pathways
Q60947864S100A10 and Cancer Hallmarks: Structure, Functions, and its Emerging Role in Ovarian Cancer
Q96576801S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1
Q55293322S100A16 up-regulates Oct4 and Nanog expression in cancer stem-like cells of Yumoto human cervical carcinoma cells.
Q47953375S100A4 Is a Biomarker and Regulator of Glioma Stem Cells That Is Critical for Mesenchymal Transition in Glioblastoma
Q64996301S100A4 May Be a Good Prognostic Marker and a Therapeutic Target for Colon Cancer.
Q92458745S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex I protein NDUFS2
Q57072975S100A4 as a Target of the E3-Ligase Asb2β and Its Effect on Engineered Heart Tissue
Q37376360S100A4 drives non-small cell lung cancer invasion, associates with poor prognosis, and is effectively targeted by the FDA-approved anti-helminthic agent niclosamide
Q26743403S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction
Q42700673S100A4 in cancer progression and metastasis: A systematic review
Q64256146S100A4 inhibits cell proliferation by interfering with the S100A1-RAGE V domain
Q47251142S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms
Q90472393S100A4 suppresses cancer stem cell proliferation via interaction with the IKK/NF-κB signaling pathway
Q54120638S100A6 promotes the proliferation and migration of cervical cancer cells via the PI3K/Akt signaling pathway.
Q39247295S100A6 protein: functional roles
Q47927472S100A7: from mechanism to cancer therapy
Q99237974S100A8 and S100A9 Promote Apoptosis of Chronic Eosinophilic Leukemia Cells
Q36287418S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival
Q57777508S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer's Disease
Q50000872S100B as an antagonist to block the interaction between S100A1 and the RAGE V domain.
Q38717429S100B impairs glycolysis via enhanced poly(ADP-ribosyl)ation of glyceraldehyde-3-phosphate dehydrogenase in rodent muscle cells
Q92283914S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis
Q36151388S100β-Positive Cells of Mesenchymal Origin Reside in the Anterior Lobe of the Embryonic Pituitary Gland
Q58749358STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia
Q99711498Schistosoma japonicum SjE16.7 Protein Promotes Tumor Development via the Receptor for Advanced Glycation End Products (RAGE)
Q37314018Serum levels of S100A6 are unaltered in patients with resectable cholangiocarcinoma
Q92636095Significance of 5-S-Cysteinyldopa as a Marker for Melanoma
Q58712956Single-cell heterogeneity in Sézary syndrome
Q97595758Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma
Q35884035Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.
Q51201229Solving the crystal structure of human calcium-free S100Z: the siege and conquer of one of the last S100 family strongholds.
Q36419214Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.
Q49316629Suppression Colitis and Colitis-Associated Colon Cancer by Anti-S100a9 Antibody in Mice
Q36783309Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex
Q91620971TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis
Q38595544Targeting danger-associated molecular patterns after myocardial infarction
Q39178065The Microenvironmental Landscape of Brain Tumors
Q39061503The Multiple Roles of Exosomes in Metastasis
Q34463903The calcium-sensing receptor: A promising target for prevention of colorectal cancer.
Q47682759The importance of calprotectin levels in obstructive sleep apnea syndrome severity
Q26749135The life and works of S100P - from conception to cancer
Q38598852The role of S100 proteins and their receptor RAGE in pancreatic cancer
Q41396244The tumor microenvironment and inflammatory breast cancer
Q37179521The tumor microenvironment: An irreplaceable element of tumor budding and epithelial-mesenchymal transition-mediated cancer metastasis
Q48181383Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma.
Q30924798Toward predicting metastatic progression of melanoma based on gene expression data
Q37619731Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer
Q61797276Transcriptomic and ChIP-sequence interrogation of EGFR signaling in HER2+ breast cancer cells reveals a dynamic chromatin landscape and S100 genes as targets
Q93040540Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients
Q98164431Unveiling functional heterogeneity in breast cancer multicellular tumor spheroids through single-cell RNA-seq
Q38909800Why Calcium? How Calcium Became the Best Communicator
Q48234052X-ray crystal structure of human calcium-bound S100A1.
Q92256343ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins

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