Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells

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Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.181.7.4666
P3181OpenCitations bibliographic resource ID142216
P932PMC publication ID2810501
P698PubMed publication ID18802069
P5875ResearchGate publication ID23267466

P50authorDirk FoellQ90119958
P2093author name stringHudson H Freeze
Pratima Sinha
Geetha Srikrishna
Suzanne Ostrand-Rosenberg
Chinonyerem Okoro
P2860cites workRAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptidesQ22010236
Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesionQ24297271
Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitroQ24540945
Inflammation and cancerQ24649640
RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesisQ24658378
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Inflammation and cancer: back to Virchow?Q28036756
Phagocyte-specific S100 proteins: a novel group of proinflammatory moleculesQ28191271
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shockQ28244377
S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end productsQ28276090
NF-kappaB: linking inflammation and immunity to cancer development and progressionQ29614597
S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional rolesQ29620465
A novel anionic modification of N-glycans on mammalian endothelial cells is recognized by activated neutrophils and modulates acute inflammatory responsesQ31725434
Cluster analysis of S100 gene expression and genes correlating to psoriasin (S100A7) expression at different stages of breast cancer developmentQ33226704
Blockade of S100A8 and S100A9 suppresses neutrophil migration in response to lipopolysaccharideQ73827858
Absence of S100A12 in mouse: implications for RAGE-S100A12 interactionQ79329828
Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cellsQ80274418
Calcium-binding proteins S100A8 and S100A9 as novel diagnostic markers in human prostate cancerQ80404832
Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 responseQ80582229
Carboxylated glycans mediate colitis through activation of NF-kappa BQ81322399
The hetero-oligomeric complex of the S100A8/S100A9 protein is extremely protease resistantQ81441207
CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cellsQ81598364
Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species.Q34287902
A cytokine-mediated link between innate immunity, inflammation, and cancerQ34625152
Myeloid cell function in MRP-14 (S100A9) null miceQ34783815
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cellsQ35052425
L-arginine metabolism in myeloid cells controls T-lymphocyte functions.Q35155944
Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progressionQ35478848
Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammationQ35776579
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapyQ36108095
Tumor immunity: a balancing act between T cell activation, macrophage activation and tumor-induced immune suppressionQ36118293
Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppressionQ36259867
Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor functionQ36384598
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinomaQ36403544
RAGE signaling sustains inflammation and promotes tumor developmentQ36502858
S100A8 and S100A9 in inflammation and cancerQ36538576
Leukocytes, inflammation, and angiogenesis in cancer: fatal attractionsQ36540110
S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern moleculesQ36582027
Altered macrophage differentiation and immune dysfunction in tumor developmentQ36809767
S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathwayQ37331858
N -Glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowthQ38290193
Gene expression profiling of ductal carcinomas in situ and invasive breast tumorsQ38351944
S100A8 and S100A9 overexpression is associated with poor pathological parameters in invasive ductal carcinoma of the breastQ39974430
Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice.Q39997114
Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristicsQ40011425
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activityQ40013431
CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cellsQ40259796
Inflammation induces myeloid-derived suppressor cells that facilitate tumor progressionQ40338318
Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activityQ40372686
Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease.Q40474320
Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regressionQ40513415
The S100 family heterodimer, MRP-8/14, binds with high affinity to heparin and heparan sulfate glycosaminoglycans on endothelial cellsQ40766569
High level expression and dimer characterization of the S100 EF-hand proteins, migration inhibitory factor-related proteins 8 and 14.Q41032857
Expression and complex assembly of calcium-binding proteins MRP8 and MRP14 during differentiation of murine myelomonocytic cellsQ41588196
The terminology issue for myeloid-derived suppressor cellsQ42425163
IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing miceQ44259082
VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression.Q51030448
Myeloid dendritic cell precursors generated from bone marrow suppress T cell responses via cell contact and nitric oxide production in vitro.Q52032290
Expression of S100 proteins in normal human tissues and common cancers using tissue microarrays: S100A6, S100A8, S100A9 and S100A11 are all overexpressed in common cancers.Q53360582
Immunohistochemical investigation of S100A9 expression in pulmonary adenocarcinoma: S100A9 expression is associated with tumor differentiation.Q53399888
Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry.Q53629351
Reduction of established spontaneous mammary carcinoma metastases following immunotherapy with major histocompatibility complex class II and B7.1 cell-based tumor vaccines.Q54142377
Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing HostQ57054792
Two proteins modulating transendothelial migration of leukocytes recognize novel carboxylated glycans on endothelial cellsQ73630482
Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen speciesQ73719137
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)4666-75
P577publication date2008-10-01
P1433published inJournal of ImmunologyQ3521441
P1476titleProinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells
P478volume181

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Q27024450S100A8 and S100A9 in cardiovascular biology and disease
Q35649454S100A8 and S100A9: new insights into their roles in malignancy
Q52725174S100A8/A9 Drives Neuroinflammatory Priming and Protects against Anxiety-like Behavior after Sepsis.
Q34802977S100A8/A9 activate key genes and pathways in colon tumor progression
Q36640358S100A8/A9 is associated with estrogen receptor loss in breast cancer
Q90064240S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis
Q34150479S100A9 a new marker for monocytic human myeloid-derived suppressor cells.
Q36287418S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival
Q34821218S100B attenuates microglia activation in gliomas: possible role of STAT3 pathway
Q37051646S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages
Q36733391STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients
Q99711498Schistosoma japonicum SjE16.7 Protein Promotes Tumor Development via the Receptor for Advanced Glycation End Products (RAGE)
Q59800492Sepsis-Induced Immunosuppression in Neonates
Q39012704Serum amyloid A3 exacerbates cancer by enhancing the suppressive capacity of myeloid-derived suppressor cells via TLR2-dependent STAT3 activation
Q64103178Serum biomarkers identification by iTRAQ and verification by MRM: S100A8/S100A9 levels predict tumor-stroma involvement and prognosis in Glioblastoma
Q46375692Serum inhibits the immunosuppressive function of myeloid-derived suppressor cells isolated from 4T1 tumor-bearing mice
Q38939956Signal transducer and activator of transcription proteins: regulators of myeloid-derived suppressor cell-mediated immunosuppression in cancer
Q38204175Signaling pathways involved in MDSC regulation
Q59335796Single-Cell Transcriptomics in Cancer Immunobiology: The Future of Precision Oncology
Q48047291Small GTPase RBJ promotes cancer progression by mobilizing MDSCs via IL-6.
Q90250634Specific Commensal Bacterium Critically Regulates Gut Microbiota Osteoimmunomodulatory Actions During Normal Postpubertal Skeletal Growth and Maturation
Q38015229Strategies for the discovery and development of therapies for metastatic breast cancer
Q47745185Strategies to Improve Vaccine Efficacy against Tuberculosis by Targeting Innate Immunity
Q35033957Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination
Q46064256Surface Glycoproteins of Exosomes Shed by Myeloid-Derived Suppressor Cells Contribute to Function
Q96167094Surgical trauma-induced immunosuppression in cancer: Recent advances and the potential therapies
Q33919802T cells contribute to tumor progression by favoring pro-tumoral properties of intra-tumoral myeloid cells in a mouse model for spontaneous melanoma
Q39218352T helper type 17 cells contribute to anti-tumour immunity and promote the recruitment of T helper type 1 cells to the tumour.
Q38103582T-cell tolerance in cancer
Q36809157TNF Neutralization Results in the Delay of Transplantable Tumor Growth and Reduced MDSC Accumulation
Q36357903TNF signaling drives myeloid-derived suppressor cell accumulation
Q58801821TNFR1 Signaling Contributes to T Cell Anergy During Sepsis
Q50924516TNFα-induced M-MDSCs promote transplant immune tolerance via nitric oxide.
Q47765346Targeting Myeloid-Derived Suppressor Cells in Cancer
Q39044981Targeting cancer-related inflammation in the era of immunotherapy
Q84474553Targeting myeloid regulatory cells in cancer by chemotherapeutic agents
Q30413623Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer
Q38686477Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective.
Q38805897Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy
Q21245714Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors
Q38812152Tasquinimod inhibits prostate cancer growth in bone through alterations in the bone microenvironment
Q35071167Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models
Q36370409Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment
Q39360781Tasquinimod: a novel drug in advanced prostate cancer
Q90056672The Engagement Between MDSCs and Metastases: Partners in Crime
Q38953395The Measure of DAMPs and a role for S100A8 in recruiting suppressor cells in breast cancer lung metastasis
Q28388630The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
Q98735532The New Era of Cancer Immunotherapy: Targeting Myeloid-Derived Suppressor Cells to Overcome Immune Evasion
Q28076760The Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer Progression
Q38774994The Role of Myeloid-Derived Suppressor Cells in Viral Infection
Q28077740The Role of Toll-Like Receptors in Hematopoietic Malignancies
Q26799120The Tumor Macroenvironment: Cancer-Promoting Networks Beyond Tumor Beds
Q59804789The Yin and Yang of Myeloid Derived Suppressor Cells
Q36072831The anti-tumor effect of the quinoline-3-carboxamide tasquinimod: blockade of recruitment of CD11b(+) Ly6C(hi) cells to tumor tissue reduces tumor growth
Q38649547The immunobiology of myeloid-derived suppressor cells in cancer
Q58763732The immunomodulatory quinoline-3-carboxamide paquinimod reverses established fibrosis in a novel mouse model for liver fibrosis
Q33660069The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.
Q37507187The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis
Q52764597The novel α-glucan YCP improves the survival rates and symptoms in septic mice by regulating myeloid-derived suppressor cells.
Q88738698The potential importance of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of Alzheimer's disease
Q34342357The pre-metastatic niche: finding common ground
Q48367212The ratio of HLA-DR and VNN2+ expression on CD14+ myeloid derived suppressor cells can distinguish glioblastoma from radiation necrosis patients
Q37212720The receptor RAGE: Bridging inflammation and cancer
Q33709243The receptor for advanced glycation end products promotes pancreatic carcinogenesis and accumulation of myeloid-derived suppressor cells
Q38239562The roles of myeloid-derived suppressor cells in transplantation
Q41379079Tolerance and immune suppression in the tumor microenvironment
Q47123300Toll-like receptor 2 ligand and interferon-γ suppress anti-tumor T cell responses by enhancing the immunosuppressive activity of monocytic myeloid-derived suppressor cells
Q40064673Top-down analysis of low mass proteins in exosomes shed by murine myeloid-derived suppressor cells
Q54940259Tracking the fate of adoptively transferred myeloid-derived suppressor cells in the primary breast tumor microenvironment.
Q92072049Transcriptome Analysis Identifies Immune Markers Related to Visceral Leishmaniasis Establishment in the Experimental Model of BALB/c Mice
Q47553626Transitory presence of myeloid-derived suppressor cells in neonates is critical for control of inflammation.
Q57299995Translational Potential of Therapeutics Targeting Regulatory Myeloid Cells in Tuberculosis
Q38067642Tumor microenvironment and myeloid-derived suppressor cells
Q91729690Tumor microenvironment-derived S100A8/A9 is a novel prognostic biomarker for advanced melanoma patients and during immunotherapy with anti-PD-1 antibodies
Q37982937Tumor microenvironment: a main actor in the metastasis process.
Q28392873Tumor necrosis factor links chronic obstructive pulmonary disease and K-ras mutant lung cancer through induction of an immunosuppressive pro-tumor microenvironment
Q37594369Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation
Q34044797Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages
Q36905043Tumor-induced myeloid-derived suppressor cell function is independent of IFN-γ and IL-4Rα.
Q35169807Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer.
Q37597961Tumor-mediated inhibition of dendritic cell differentiation is mediated by down regulation of protein kinase C beta II expression
Q39064350Tumour-activated liver stromal cells regulate myeloid-derived suppressor cells accumulation in the liver
Q38193589Tumour-induced immune suppression: role of inflammatory mediators released by myelomonocytic cells.
Q34163882Type 1 T Helper Cells Induce the Accumulation of Myeloid-Derived Suppressor Cells in the Inflamed Tgfb1 Knockout Mouse Liver
Q47615254Ubiquitin Conjugation Probed by Inflammation in Myeloid-Derived Suppressor Cell Extracellular Vesicles.
Q26744481Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype
Q41114263Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment
Q34259719Vitamin D analog calcipotriol suppresses the Th17 cytokine-induced proinflammatory S100 "alarmins" psoriasin (S100A7) and koebnerisin (S100A15) in psoriasis
Q41858851Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma.
Q35207111Δ9-Tetrahydrocannabinol-mediated epigenetic modifications elicit myeloid-derived suppressor cell activation via STAT3/S100A8

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