scholarly article | Q13442814 |
P356 | DOI | 10.1007/S00018-018-2844-6 |
P698 | PubMed publication ID | 29779041 |
P2093 | author name string | Kai Kaarniranta | |
Antero Salminen | |||
Anu Kauppinen | |||
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Microglial activation milieu controls regulatory T cell responses. | Q48920809 | ||
Myeloid-Derived Suppressor Cells Induce the Expansion of Regulatory B Cells and Ameliorate Autoimmunity in the Sanroque Mouse Model of Systemic Lupus Erythematosus | Q48955929 | ||
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How plausible is a link between HSV-1 infection and Alzheimer's disease? | Q51850423 | ||
Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-alpha-dependent. | Q51957782 | ||
Elimination of GD3 synthase improves memory and reduces amyloid-beta plaque load in transgenic mice. | Q51964751 | ||
Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model. | Q53287908 | ||
Intracellular Aβ-oligomers and early inflammation in a model of Alzheimer's disease. | Q53317540 | ||
Neuronal driven pre-plaque inflammation in a transgenic rat model of Alzheimer's disease. | Q53352665 | ||
Altered arginine metabolism in Alzheimer's disease brains. | Q53463642 | ||
Tumor necrosis factor-α blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation. | Q54269192 | ||
Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. | Q54421148 | ||
IL-18 Induces PD-1-Dependent Immunosuppression in Cancer | Q57556330 | ||
PD1 Negative and PD1 Positive CD4+ T Regulatory Cells in Mild Cognitive Impairment and Alzheimer's Disease | Q57997425 | ||
Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice | Q77384367 | ||
Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells | Q80274418 | ||
Crucial role of granulocytic myeloid-derived suppressor cells in the regulation of central nervous system autoimmune disease | Q83160725 | ||
Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF | Q83300302 | ||
Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs | Q85522762 | ||
Increased abundance of myeloid-derived suppressor cells and Th17 cells in peripheral blood of newly-diagnosed Parkinson's disease patients | Q87709432 | ||
Interleukin 33 in tumor microenvironment is crucial for the accumulation and function of myeloid-derived suppressor cells | Q36597506 | ||
Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival | Q36602163 | ||
Neuroinflammatory phenotype in early Alzheimer's disease | Q36629135 | ||
The role of complement component 3 (C3) in differentiation of myeloid-derived suppressor cells | Q36666775 | ||
STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients | Q36733391 | ||
Myeloid-Derived Suppressor Cell Survival and Function Are Regulated by the Transcription Factor Nrf2. | Q36767546 | ||
Isolation and Flow Cytometric Analysis of Immune Cells from the Ischemic Mouse Brain | Q36788361 | ||
Premetastatic soil and prevention of breast cancer brain metastasis | Q36943888 | ||
Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. | Q36982546 | ||
Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression | Q36983876 | ||
Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta | Q36996975 | ||
Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice | Q37003128 | ||
Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain | Q37053459 | ||
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology | Q37113528 | ||
IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression | Q37342418 | ||
Arginase: an emerging key player in the mammalian immune system | Q37395887 | ||
NF-kappaB in the nervous system | Q37412663 | ||
Inflammation in Alzheimer's disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors | Q37456664 | ||
Siglec receptors and hiding plaques in Alzheimer's disease | Q37458265 | ||
Clusterin: a forgotten player in Alzheimer's disease | Q37570713 | ||
CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis | Q37591247 | ||
Pericyte loss influences Alzheimer-like neurodegeneration in mice. | Q37623577 | ||
The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases. | Q37777395 | ||
Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function | Q37808561 | ||
Regulation and functions of the IL-10 family of cytokines in inflammation and disease | Q37821924 | ||
Role of toll-like receptors in cardiovascular diseases | Q37854080 | ||
Prostaglandins and chronic inflammation | Q37998619 | ||
T-cell trafficking in the central nervous system | Q38020964 | ||
The potential role of proinflammatory and antiinflammatory cytokines in Alzheimer disease pathogenesis. | Q38042681 | ||
PGE(2)-driven induction and maintenance of cancer-associated myeloid-derived suppressor cells | Q38047052 | ||
microRNAs as potential regulators of myeloid-derived suppressor cell expansion | Q38113760 | ||
Pathways mediating resolution of inflammation: when enough is too much | Q38116494 | ||
STAT3 activation: A key factor in tumor immunoescape | Q38140901 | ||
The Potential Role of Chemokines in Alzheimer's Disease Pathogenesis | Q38177234 | ||
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Q29614879 | ||
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders | Q29615839 | ||
Amyloid deposition as the central event in the aetiology of Alzheimer's disease | Q29619450 | ||
Astrocytes are active players in cerebral innate immunity | Q29620562 | ||
TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation | Q30176406 | ||
Myeloid-derived suppressor cells: the dark knight or the joker in viral infections? | Q30411008 | ||
Macrophage migration inhibitory factor promotes tumor growth and metastasis by inducing myeloid-derived suppressor cells in the tumor microenvironment | Q30415763 | ||
Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models. | Q30634663 | ||
Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology | Q30658083 | ||
Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology. | Q30805627 | ||
Brain imaging of neurovascular dysfunction in Alzheimer's disease | Q31066988 | ||
Serum MCP-1 levels are increased in mild cognitive impairment and mild Alzheimer's disease | Q33227799 | ||
PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation | Q33569771 | ||
Neurotoxic reactive astrocytes are induced by activated microglia | Q33602850 | ||
Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells | Q33707270 | ||
Regulatory T cells in multiple sclerosis and myasthenia gravis. | Q33784969 | ||
IL-4 signaling drives a unique arginase+/IL-1β+ microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after traumatic spinal cord injury | Q33801629 | ||
Trafficking of immune cells in the central nervous system | Q33815795 | ||
Interleukin-6 induces Gr-1+CD11b+ myeloid cells to suppress CD8+ T cell-mediated liver injury in mice | Q33843364 | ||
Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer's disease | Q33943122 | ||
Lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors | Q34145236 | ||
The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors | Q34228171 | ||
HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment | Q34243443 | ||
Toll-like receptor 2 controls expansion and function of regulatory T cells | Q34264024 | ||
TGFβ signaling plays a critical role in promoting alternative macrophage activation | Q34306291 | ||
The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells | Q34315871 | ||
HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells | Q34353413 | ||
Transgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's disease | Q34358146 | ||
Microglial phenotype and adaptation | Q34359569 | ||
Suppression of antigen presentation by IL-10 | Q34458595 | ||
Non-steroidal anti-inflammatory drugs as a treatment for Alzheimer's disease: a systematic review and meta-analysis of treatment effect | Q34460952 | ||
Effect of TLR agonists on the differentiation and function of human monocytic myeloid-derived suppressor cells | Q34469457 | ||
Regulatory B cells: origin, phenotype, and function. | Q34473148 | ||
Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo | Q34633199 | ||
Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain | Q34695396 | ||
Myeloid Cells in the Central Nervous System | Q39388337 | ||
Regulatory T cells delay disease progression in Alzheimer-like pathology. | Q39970717 | ||
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease. | Q40154608 | ||
IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. | Q40265668 | ||
Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression | Q40338318 | ||
Herpes and Alzheimer's Disease: Subversion in the Central Nervous System and How It Might Be Halted | Q40496137 | ||
Emerging roles of myeloid derived suppressor cells in hepatic inflammation and fibrosis | Q40614034 | ||
CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells | Q40619963 | ||
Cell trafficking through the choroid plexus | Q41196854 | ||
Modulation of Immune Responses to Herpes Simplex Virus Type 1 by IFNL3 and IRF7 Polymorphisms: A Study in Alzheimer's Disease. | Q41922958 | ||
Myeloid-Derived Suppressor Cells Inhibit T Follicular Helper Cell Immune Response in Japanese Encephalitis Virus Infection. | Q41924234 | ||
Heterogeneous induction of microglia M2a phenotype by central administration of interleukin-4. | Q42014501 | ||
Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain. | Q42126859 | ||
HMGB1 promotes myeloid-derived suppressor cells and renal cell carcinoma immune escape | Q42149043 | ||
IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior. | Q42174144 | ||
Celecoxib inhibits CD133-positive cell migration via reduction of CCR2 in Helicobacter pylori-infected Mongolian gerbils | Q43188046 | ||
Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease | Q43736405 | ||
Innate immune CD11b+Gr-1+ cells, suppressor cells, affect the immune response during Theiler's virus-induced demyelinating disease | Q43906234 | ||
T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response | Q45292627 | ||
Granulocytic myeloid-derived suppressor cells are cryosensitive and their frequency does not correlate with serum concentrations of colony-stimulating factors in head and neck cancer | Q45344986 | ||
Ly6C+ Ly6G- Myeloid-derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury. | Q45908055 | ||
Abeta-specific T-cells reverse cognitive decline and synaptic loss in Alzheimer's mice. | Q46141854 | ||
Alzheimer's disease: A matter of blood-brain barrier dysfunction? | Q46165463 | ||
Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease. | Q46535303 | ||
IL-18 enhances immunosuppressive responses by promoting differentiation into monocytic myeloid-derived suppressor cells | Q46819279 | ||
A complex proinflammatory role for peripheral monocytes in Alzheimer's disease. | Q46827803 | ||
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease | Q46942969 | ||
The regulation of immune tolerance by FOXP3. | Q48010811 | ||
TREM2 expression in the human brain: a marker of monocyte recruitment? | Q48029728 | ||
Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients | Q48093126 | ||
Capillary dysfunction is associated with symptom severity and neurodegeneration in Alzheimer's disease | Q48244938 | ||
Regulatory T cells inhibit microglia activation and protect against inflammatory injury in intracerebral hemorrhage | Q48259284 | ||
Keeping the eIF2 alpha kinase Gcn2 in check | Q38204568 | ||
Microglial diversity by responses and responders | Q38205433 | ||
Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages | Q38266887 | ||
T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases | Q38274179 | ||
Mechanisms of intimate and long-distance cross-talk between glioma and myeloid cells: how to break a vicious cycle. | Q38277068 | ||
miR-34a expands myeloid-derived suppressor cells via apoptosis inhibition | Q38307450 | ||
Regulation of clusterin gene expression by transforming growth factor beta | Q38342490 | ||
Migration of blood cells to β-amyloid plaques in Alzheimer's disease | Q38370756 | ||
TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function. | Q38384707 | ||
Alternatively activated microglia and macrophages in the central nervous system. | Q38525488 | ||
Origin of microglia: current concepts and past controversies | Q38541717 | ||
Linking T cells to Alzheimer's disease: from neurodegeneration to neurorepair | Q38620161 | ||
Myeloid derived suppressor cells in inflammatory conditions of the central nervous system. | Q38623022 | ||
Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke | Q38623025 | ||
Myeloid cell distribution and activity in multiple sclerosis. | Q38642525 | ||
Differential Phenotypes of Myeloid-Derived Suppressor and T Regulatory Cells and Cytokine Levels in Amnestic Mild Cognitive Impairment Subjects Compared to Mild Alzheimer Diseased Patients | Q38652940 | ||
CXCL2/MIF-CXCR2 signaling promotes the recruitment of myeloid-derived suppressor cells and is correlated with prognosis in bladder cancer | Q38741840 | ||
Peripheral Immune Signatures in Alzheimer Disease | Q38743224 | ||
The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease. | Q38779167 | ||
TGF-β: the master regulator of fibrosis | Q38816052 | ||
Pericytes of the neurovascular unit: key functions and signaling pathways. | Q38844788 | ||
Norepinephrine-induced myeloid-derived suppressor cells block T-cell responses via generation of reactive oxygen species | Q38855467 | ||
A polarizing question: do M1 and M2 microglia exist? | Q38908868 | ||
Hypoxia Enhances Immunosuppression by Inhibiting CD4+ Effector T Cell Function and Promoting Treg Activity | Q38917327 | ||
Signal transducer and activator of transcription proteins: regulators of myeloid-derived suppressor cell-mediated immunosuppression in cancer | Q38939956 | ||
On the origin of myeloid-derived suppressor cells. | Q38968944 | ||
The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells | Q38998427 | ||
Microglia in Physiology and Disease. | Q39037459 | ||
Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease | Q39041998 | ||
Selective Targeting of Myeloid-Derived Suppressor Cells in Cancer Patients Using DS-8273a, an Agonistic TRAIL-R2 Antibody. | Q39103948 | ||
Microglia Function in the Central Nervous System During Health and Neurodegeneration | Q39146780 | ||
Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer | Q39188755 | ||
Elucidating the Role of TREM2 in Alzheimer's Disease | Q39252469 | ||
Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease | Q39313671 | ||
A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma | Q34699543 | ||
CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages. | Q34718815 | ||
COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells | Q34784887 | ||
Modulation of the antitumor immune response by complement | Q34838919 | ||
Cerebral regulatory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10. | Q34945037 | ||
DAMP signaling is a key pathway inducing immune modulation after brain injury. | Q34946249 | ||
Protein tyrosine phosphatase 1B deficiency ameliorates murine experimental colitis via the expansion of myeloid-derived suppressor cells | Q34947778 | ||
S100A8 and S100A9 induce cytokine expression and regulate the NLRP3 inflammasome via ROS-dependent activation of NF-κB(1.). | Q34973392 | ||
Glioma cancer stem cells induce immunosuppressive macrophages/microglia | Q34992518 | ||
Anti-HMGB1 monoclonal antibody ameliorates immunosuppression after peripheral tissue trauma: attenuated T-lymphocyte response and increased splenic CD11b (+) Gr-1 (+) myeloid-derived suppressor cells require HMGB1. | Q35076030 | ||
Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease | Q35080639 | ||
Myeloid-derived suppressor cells regulate T cell and B cell responses during autoimmune disease | Q35115477 | ||
HIF transcription factors, inflammation, and immunity | Q35137138 | ||
Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology | Q35155067 | ||
L-arginine metabolism in myeloid cells controls T-lymphocyte functions. | Q35155944 | ||
Complexity and challenges in defining myeloid-derived suppressor cells | Q35509317 | ||
Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. | Q35553327 | ||
Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b+Gr1+ cells | Q35566772 | ||
The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain. | Q35599843 | ||
Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms | Q35674290 | ||
Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology | Q35813745 | ||
Regulatory T cells: friend or foe in immunity to infection? | Q35934156 | ||
HMGB1 is a therapeutic target for sterile inflammation and infection | Q35953553 | ||
Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology | Q36018333 | ||
Microglia in Alzheimer's Disease: It's All About Context | Q36072124 | ||
Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease | Q36150463 | ||
Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer's disease | Q36180652 | ||
Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer's disease-like mice | Q36180666 | ||
Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer's Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry. | Q36226843 | ||
Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition | Q36232140 | ||
Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer | Q36260673 | ||
Myeloid derived suppressor cells in human diseases | Q36338349 | ||
Noncanonical NF-κB activation mediates STAT3-stimulated IDO upregulation in myeloid-derived suppressor cells in breast cancer | Q36481359 | ||
Myeloid dendritic cells are decreased in peripheral blood of Alzheimer's disease patients in association with disease progression and severity of depressive symptoms. | Q36503723 | ||
P433 | issue | 17 | |
P921 | main subject | Alzheimer's disease | Q11081 |
P304 | page(s) | 3099-3120 | |
P577 | publication date | 2018-05-19 | |
P1433 | published in | Cellular and Molecular Life Sciences | Q5058352 |
P1476 | title | The potential importance of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of Alzheimer's disease | |
P478 | volume | 75 |
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Q59136184 | Functional alterations of myeloid cells during the course of Alzheimer's disease |
Q59804789 | The Yin and Yang of Myeloid Derived Suppressor Cells |
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