Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties.

scientific article

Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1189/JLB.1211639
P932PMC publication ID3427612
P698PubMed publication ID22685318

P50authorHarold L. MosesQ47005604
Philip OwensQ63430786
P2093author name stringAnna Chytil
Michael W Pickup
Sergey V Novitskiy
Dina Polosukhina
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Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gammaQ40907616
Transforming growth factor-beta 1 inhibits scavenger receptor activity in THP-1 human macrophagesQ41653372
An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and miceQ42652064
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Smad4 signalling in T cells is required for suppression of gastrointestinal cancer.Q54462818
TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cellsQ57218941
Deactivation of macrophages by transforming growth factor-βQ59068031
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesisQ59276609
Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10.Q64903823
Type I transforming growth factor-beta receptors on neutrophils mediate chemotaxis to transforming growth factor-betaQ68251070
Contrasting effects of TGF-beta 1 and TNF-alpha on the development of dendritic cells from progenitors in mouse bone marrowQ73197413
MMP-9 is differentially expressed in primary human colorectal adenocarcinomas and their metastasesQ83315903
Conditional deletion of TGF-βR1 using Langerin-Cre mice results in Langerhans cell deficiency and reduced contact hypersensitivityQ85094762
Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cellsQ24658240
Myeloid-derived suppressor cells as regulators of the immune systemQ28131637
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Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasisQ28592128
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptorQ28593665
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytesQ29547633
Subsets of myeloid-derived suppressor cells in tumor-bearing miceQ29614297
Macrophage diversity enhances tumor progression and metastasisQ29615847
Transforming growth factor-beta 1 inhibition of macrophage activation is mediated via Smad3.Q33916695
TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progressionQ33936542
The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasisQ34249064
Transforming growth factor type beta induces monocyte chemotaxis and growth factor productionQ34339289
S100A8/A9 activate key genes and pathways in colon tumor progressionQ34802977
Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinomaQ35369888
Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in miceQ35370005
A critical role for macrophages in promotion of urethane-induced lung carcinogenesisQ35566757
Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing miceQ35648172
The biology of myeloid‐derived suppressor cells: The blessing and the curse of morphological and functional heterogeneityQ35750663
TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanismsQ35814020
Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progressionQ36026081
Transforming growth factor beta enhances integrin expression and type IV collagenase secretion in human monocytesQ36305926
Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor betaQ36350227
Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor betaQ36362135
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasisQ36464443
Myeloid-derived suppressor cellsQ36916250
Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells.Q37118160
Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancerQ37209259
Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer?Q37326107
P433issue3
P304page(s)641-651
P577publication date2012-06-08
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleDeletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties
P478volume92

Reverse relations

cites work (P2860)
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