NF-kappaB: linking inflammation and immunity to cancer development and progression

scientific article (publication date: October 2005)

NF-kappaB: linking inflammation and immunity to cancer development and progression is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1038/NRI1703
P3181OpenCitations bibliographic resource ID479732
P698PubMed publication ID16175180
P5875ResearchGate publication ID7589085

P50authorMichael KarinQ1458081
Florian GretenQ17321656
P2860cites workThe Hallmarks of CancerQ221226
A proinflammatory cytokine inhibits p53 tumor suppressor activityQ22010796
IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesisQ24320080
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responsesQ24562026
Inflammation and cancerQ24649640
Inflammation and cancer: back to Virchow?Q28036756
Interleukin-1 polymorphisms associated with increased risk of gastric cancerQ28140456
Non-steroidal anti-inflammatory drug use and the risk of gastric cancer: a systematic review and meta-analysisQ28166328
A prospective study of aspirin use and the risk of pancreatic cancer in womenQ28166674
Aspirin for cancer chemoprevention: still a headache?Q28167300
Aspirin and the risk of Hodgkin's lymphoma in a population-based case-control studyQ28167302
Regulation of cutaneous malignancy by gammadelta T cellsQ28188439
Association of aspirin and other non-steroidal anti-inflammatory drug use with incidence of non-Hodgkin lymphomaQ28196753
NF-kappaB regulation in the immune systemQ28205043
COX-2 inhibition and colorectal cancerQ28208652
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trialQ28217835
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatasesQ28239642
IL-1 is required for tumor invasiveness and angiogenesisQ28594748
Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseasesQ29547555
Signaling to NF-kappaBQ29547844
Missing pieces in the NF-kappaB puzzleQ29547864
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survivalQ29547865
Tumour-educated macrophages promote tumour progression and metastasisQ29614307
The two NF-kappaB activation pathways and their role in innate and adaptive immunityQ29614355
NF-kappaB functions as a tumour promoter in inflammation-associated cancerQ29614598
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancerQ29614599
NF-kappaB in cancer: from innocent bystander to major culpritQ29614603
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposisQ29616121
The immunobiology of cancer immunosurveillance and immunoeditingQ29616246
Smoldering and polarized inflammation in the initiation and promotion of malignant diseaseQ29618034
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instabilityQ29618122
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma preventionQ29620087
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicityQ29620119
Perforin and interferon-gamma activities independently control tumor initiation, growth, and metastasis.Q31775425
Possible role of ovarian epithelial inflammation in ovarian cancerQ33724007
Liver regenerationQ33870218
Infections as a major preventable cause of human cancerQ33916455
Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.Q33967257
Tumor angiogenesis, macrophages, and cytokinesQ34009001
Cytokines in cancer pathogenesis and cancer therapyQ34288123
Addicted to death: invasive cancer and the immune response to unscheduled cell deathQ34378991
Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expressionQ34467878
Tumor necrosis factor or tumor promoting factor?Q34568701
von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arraysQ34784862
Nature's TRAIL--on a path to cancer immunotherapyQ35046572
Does the immune system see tumors as foreign or self?Q35077428
The IKK NF-kappa B system: a treasure trove for drug developmentQ35621375
Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease.Q35806727
Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.Q35913517
Inflammation as a tumor promoter in cancer inductionQ35920466
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosisQ36368249
The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancerQ36371644
Regulation of the chemokine receptor CXCR4 by hypoxiaQ36371842
Tumor necrosis factor sustains the generalized lymphoproliferative disorder (gld) phenotypeQ36375875
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent miceQ36497106
Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibitionQ37415678
NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK.Q40431585
Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regressionQ40513415
Helicobacter pylori infection activates NF-kappa B in gastric epithelial cellsQ41088207
Tumour necrosis factor-alpha mediates tumour promotion via a PKC alpha- and AP-1-dependent pathwayQ42523288
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cellsQ42947524
Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: role of proteasesQ43612862
Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour developmentQ44683813
NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.Q45982548
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependentQ46068963
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesisQ46576855
CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice.Q51463026
Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization.Q53384485
TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.Q54697386
The epidemiology of gastric cancerQ57586419
Macrophage infiltration is associated with VEGF and EGFR expression in breast cancerQ58212139
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammationQ59054264
Sequence Variants in Toll-Like Receptor Gene Cluster (TLR6-TLR1-TLR10) and Prostate Cancer RiskQ61853345
c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skinQ73291709
Increased mast cell density in invasive melanomaQ74330260
Inhibition of Rel/Nuclear Factor-kappaB signaling in skin results in defective DNA damage-induced cell cycle arrest and Ha-ras- and p53-independent tumor developmentQ74463183
Inflammation and necrosis promote tumour growthQ80402773
Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-AQ80501633
Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesisQ80998934
Gastric cancer originating from bone marrow-derived cellsQ81067451
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
inflammationQ101991
P304page(s)749-759
P577publication date2005-10-01
P1433published inNature Reviews ImmunologyQ43355
P1476titleNF-kappaB: linking inflammation and immunity to cancer development and progression
P478volume5

Reverse relations

cites work (P2860)
Q36681789(E)-2,4-bis(p-hydroxyphenyl)-2-butenal has an antiproliferative effect on NSCLC cells induced by p38 MAPK-mediated suppression of NF-κB and up-regulation of TNFRSF10B (DR5).
Q3399721417-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition
Q422178502011: the immune hallmarks of cancer
Q898347792α-Hydroxyeudesma-4,11(13)-Dien-8β,12-Olide Isolated from Inula britannica Induces Apoptosis in Diffuse Large B-cell Lymphoma Cells
Q355335213,4-Dihydroxy-benzohydroxamic acid (Didox) suppresses pro-inflammatory profiles and oxidative stress in TLR4-activated RAW264.7 murine macrophages
Q462542228-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions.
Q333990689-Aminoacridine-based anticancer drugs target the PI3K/AKT/mTOR, NF-kappaB and p53 pathways
Q53295110A Role for Lymphotoxin in Primary Sjögren’s Disease
Q47262769A common variant in the precursor miR-146a sequence does not predispose to cholangiocarcinoma in a large European cohort.
Q35108769A compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines
Q34625152A cytokine-mediated link between innate immunity, inflammation, and cancer
Q39928939A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: involvement of nuclear factor-kappaB signaling
Q36962761A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instability
Q35015686A dual role for the immune response in a mouse model of inflammation-associated lung cancer
Q37359026A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension
Q42039947A genome-wide RNA interference screen identifies caspase 4 as a factor required for tumor necrosis factor alpha signaling.
Q90069095A genome-wide screen for human salicylic acid (SA)-binding proteins reveals targets through which SA may influence development of various diseases
Q37976467A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets
Q24630221A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
Q24602478A miR-19 regulon that controls NF-κB signaling
Q28393278A multi-targeted approach to suppress tumor-promoting inflammation
Q44634969A new flavan-3-ol and the anti-inflammatory effect of flavonoids from the fruit peels of Wisteria floribunda.
Q36906449A new look at T cell receptor signaling to nuclear factor-κB
Q37490772A new multicolor bioluminescence imaging platform to investigate NF-κB activity and apoptosis in human breast cancer cells
Q37419942A new role for NFκB in immunosurveillance and its implications for cancer immunotherapy
Q41295458A new role for microRNAs, as ligands of Toll-like receptors
Q44923694A novel mechanism of tissue inhibitor of metalloproteinases-1 activation by interleukin-1 in primary human astrocytes
Q40094086A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells
Q48962375A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hit
Q83979425A phase 2 study of irinotecan, cisplatin, and simvastatin for untreated extensive-disease small cell lung cancer
Q37195823A pilot study on acute inflammation and cancer: a new balance between IFN-gamma and TGF-beta in melanoma
Q39078279A positive feedback loop between STAT3 and cyclooxygenase-2 gene may contribute to Helicobacter pylori-associated human gastric tumorigenesis
Q58543600A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas
Q35617840A quantitative model of thermal injury-induced acute inflammation
Q41892002A redox economical synthesis of bioactive 6,12-guaianolides.
Q34135803A review of the application of inflammatory biomarkers in epidemiologic cancer research
Q38093040A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2011.
Q91716396A typical carcinoid of the lung - a case report with pathological correlation and propagation of the cancer stem cell line BKZ1 with synaptophysin expression
Q36251372A20 suppresses hepatocellular carcinoma proliferation and metastasis through inhibition of Twist1 expression
Q38163423A20-mediated negative regulation of canonical NF-κB signaling pathway
Q37325315A20: central gatekeeper in inflammation and immunity
Q24336707ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB
Q39810390ABIN-1 negatively regulates NF-kappaB by inhibiting processing of the p105 precursor
Q58790965AEBP1 promotes epithelial-mesenchymal transition of gastric cancer cells by activating the NF-κB pathway and predicts poor outcome of the patients
Q92299091AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging
Q35963779ARTD1 Suppresses Interleukin 6 Expression by Repressing MLL1-Dependent Histone H3 Trimethylation.
Q37589257Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer
Q64280054Aberrant expression and high-frequency mutations of in nonmelanoma skin cancer
Q37590127Ablation of gly96/immediate early gene-X1 (gly96/iex-1) aggravates DSS-induced colitis in mice: role for gly96/iex-1 in the regulation of NF-kappaB.
Q33719713Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks
Q47119773Acquisition of EGFR TKI resistance and EMT phenotype is linked with activation of IGF1R/NF-κB pathway in EGFR-mutant NSCLC.
Q41839580Acquisition of Genetic Aberrations by Activation-Induced Cytidine Deaminase (AID) during Inflammation-Associated Carcinogenesis
Q34111440Activated macrophages in the tumour microenvironment-dancing to the tune of TLR and NF-kappaB
Q53070583Activation of AhR with nuclear IKKα regulates cancer stem-like properties in the occurrence of radioresistance.
Q45266303Activation of nuclear factor-kappa B and cell adhesion molecule mRNA expression in duodenal mucosa of dogs with lymphocytic-plasmacytic enteritis
Q90442533Activation of the Toll‑like receptor 2 signaling pathway inhibits the proliferation of HCC cells in vitro
Q28392256Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling
Q46729038Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma
Q42512219Acute inflammation regulates neuroregeneration through the NF-κB pathway in olfactory epithelium
Q33885950Adaptations to climate-mediated selective pressures in humans
Q37685442Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells
Q37036746Advances in targeting IKK and IKK-related kinases for cancer therapy
Q37462069Aging and inflammation: etiological culprits of cancer
Q35188247Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?
Q37711310Alcohol, nutrition and liver cancer: role of Toll-like receptor signaling
Q38966604Allantopyrone A, an α-pyrone metabolite from an endophytic fungus, inhibits the tumor necrosis factor α-induced nuclear factor κB signaling pathway
Q90632706Alpha-Glucosidase Inhibitor Voglibose Suppresses Azoxymethane-Induced Colonic Preneoplastic Lesions in Diabetic and Obese Mice
Q46218163Alpha-lipoic acid improves acetic acid-induced gastric ulcer healing in rats
Q33889390Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells
Q38160777Alterations in macrophages and monocytes from tumor-bearing mice: evidence of local and systemic immune impairment.
Q37041538Altered TAB1:I kappaB kinase interaction promotes transforming growth factor beta-mediated nuclear factor-kappaB activation during breast cancer progression
Q33602290Altered expression of histone deacetylases, inflammatory cytokines and contractile-associated factors in uterine myometrium of Long Evans rats gestationally exposed to benzo[a]pyrene
Q36809767Altered macrophage differentiation and immune dysfunction in tumor development
Q24294345An Atypical E3 Ligase Zinc Finger Protein 91 Stabilizes and Activates NF-κB-inducing Kinase via Lys63-linked Ubiquitination
Q36543809An evolutionarily conserved innate immunity protein interaction network
Q64068156An expanded variant list and assembly annotation identifies multiple novel coding and noncoding genes for prostate cancer risk using a normal prostate tissue eQTL data set
Q36332304An in vitro study showing the three-dimensional microenvironment influence over the behavior of head and neck squamous cell carcinoma
Q47151590An inflammation-based cumulative prognostic score system in patients with diffuse large B cell lymphoma in rituximab era.
Q36338202An integrated method for the identification of novel genes related to oral cancer
Q33528269An integrative modular approach to systematically predict gene-phenotype associations
Q38038498An overview of transcriptional regulation in response to toxicological insult.
Q90485486Annotation and cluster analysis of long noncoding RNA linked to male sex and estrogen in cancers
Q64125847Anti-IL-6 receptor mAb eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T-cell responses
Q33744128Anti-Inflammatory Activity and Structure-Activity Relationships of Brominated Indoles from a Marine Mollusc.
Q41125099Anti-Inflammatory Effects of Capsaicin and Piperine on Helicobacter pylori-Induced Chronic Gastritis in Mongolian Gerbils.
Q35821696Anti-Inflammatory Effects of Novel Standardized Solid Lipid Curcumin Formulations
Q47946921Anti-Inflammatory Effects of Schisandrin B on LPS-Stimulated BV2 Microglia via Activating PPAR-γ.
Q39566599Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF-κB.
Q53283288Anti-carcinogenic action of curcumin by activation of antioxidant defence system and inhibition of NF-κB signalling in lymphoma-bearing mice.
Q50708999Anti-fibrotic effects of tetrandrine on bile-duct ligated rats.
Q47330928Anti-inflammatory Effects of Rosmarinic Acid in Lipopolysaccharide-Induced Mastitis in Mice.
Q37679431Anti-inflammatory activity of compounds isolated from Astragalus sinicus L. in cytokine-induced keratinocytes and skin
Q47160621Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis
Q51382039Anti-rheumatic drug iguratimod (T-614) alleviates cancer-induced bone destruction via down-regulating interleukin-6 production in a nuclear factor-κB-dependent manner.
Q89407909Anti-tumor activity of wogonin, an extract from Scutellaria baicalensis, through regulating different signaling pathways
Q47133210Anticancer activity of Astragalus polysaccharide in human non-small cell lung cancer cells
Q58572122Anticancer effects of curcumin on nude mice bearing lung cancer A549 cell subsets SP and NSP cells
Q48101367Antifibrotic effects of D-limonene (5(1-methyl-4-[1-methylethenyl]) cyclohexane) in CCl4 induced liver toxicity in Wistar rats.
Q50901671Antioxidant activities of curcumin in allergic rhinitis.
Q36945706Antioxidant function of isoflavone and 3,3'-diindolylmethane: are they important for cancer prevention and therapy?
Q49097159Antisense oligonucleotides against TNFR1 prevent toxicity of TNF/IFNγ treatment in mouse tumor models
Q39399212Antitumor effect of berberine against primary effusion lymphoma via inhibition of NF-κB pathway.
Q48514273Antitumor effects of metformin are a result of inhibiting nuclear factor kappa B nuclear translocation in esophageal squamous cell carcinoma.
Q34309920Apc-Mutant Kyoto Apc Delta (KAD) Rats Are Susceptible to 4-NQO-Induced Tongue Carcinogenesis
Q55345439Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro.
Q35910652ApoM Suppresses TNF-α-Induced Expression of ICAM-1 and VCAM-1 Through Inhibiting the Activity of NF-κB
Q61835940Apoptosis Inhibition Can Be Threatening in Aβ-Induced Neuroinflammation, Through Promoting Cell Proliferation
Q33748016Apoptosis induction by 13-acetoxyrolandrolide through the mitochondrial intrinsic pathway.
Q36815310Apoptosis pathways as promising targets for skin cancer therapy
Q47354821Apoptotic Cells Induced Signaling for Immune Homeostasis in Macrophages and Dendritic Cells
Q42956874Apple, cherry, and blackcurrant increases nuclear factor kappa B activation in liver of transgenic mice.
Q38557650Applying nanomedicine in maladaptive inflammation and angiogenesis
Q38759245Arctigenin Confers Neuroprotection Against Mechanical Trauma Injury in Human Neuroblastoma SH-SY5Y Cells by Regulating miRNA-16 and miRNA-199a Expression to Alleviate Inflammation
Q26830307Are hematopoietic stem cells involved in hepatocarcinogenesis?
Q39109776Arsenic trioxide suppressed mantle cell lymphoma by downregulation of cyclin D1.
Q38725091Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathways
Q90009344Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages
Q43535631Association between NFKB1 -94ins/delATTG promoter polymorphism and cancer risk: a meta-analysis
Q49721789Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer
Q51115447Association of MAP4K4 gene single nucleotide polymorphism with mastitis and milk traits in Chinese Holstein cattle.
Q34176403Association of Mycoplasma hominis infection with prostate cancer
Q86494702Association of interleukin-10, tumor necrosis factor-α and transforming growth factor-β gene polymorphisms with the outcome of diffuse large B-cell lymphomas
Q80732292Association of progressive structural changes in the bronchial epithelium with subepithelial fibrous remodeling: a potential role for hypoxia
Q84818875Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2
Q33660226Astaxanthin protects astrocytes against trauma-induced apoptosis through inhibition of NKCC1 expression via the NF-κB signaling pathway
Q58694758Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling
Q54208087Astragalus membranaceus Extract Attenuates Inflammation and Oxidative Stress in Intestinal Epithelial Cells via NF-κB Activation and Nrf2 Response.
Q33766869Attenuation of Carcinogenesis and the Mechanism Underlying by the Influence of Indole-3-carbinol and Its Metabolite 3,3'-Diindolylmethane: A Therapeutic Marvel
Q55260178Augmented O-GlcNAcylation alleviates inflammation-mediated colon carcinogenesis via suppression of acute inflammation.
Q35085362Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model
Q38341491Aurora-A Contributes to Radioresistance by Increasing NF-κB DNA Binding
Q37696994Avian leukosis virus subgroup J induces VEGF expression via NF-κB/PI3K-dependent IL-6 production
Q42176053Awareness and current knowledge of breast cancer.
Q34059352B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression
Q64116739BAM15 attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue
Q52679779BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment.
Q34972203BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression
Q37696175Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway.
Q33737879Bacterial oncogenesis in the colon
Q34158284Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells
Q37707525Berberine affects osteosarcoma via downregulating the caspase-1/IL-1β signaling axis
Q38696079Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth
Q34685488Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin
Q29616793Beta-arrestins and cell signaling
Q36625618Betulinic acid enhances TGF-β signaling by altering TGF-β receptors partitioning between lipid-raft/caveolae and non-caveolae membrane microdomains in mink lung epithelial cells
Q89029472Beyond Cell Death: New Functions for TNF Family Cytokines in Autoimmunity and Tumor Immunotherapy
Q28743513Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers
Q36133116Bicyclic Cyclohexenones as Inhibitors of NF-κB Signaling
Q39202139Bile acids affect the growth of human cholangiocarcinoma via NF-kB pathway
Q35004559Binding of NF-κB to nucleosomes: effect of translational positioning, nucleosome remodeling and linker histone H1.
Q33684696Bioactive sesquiterpene lactones and other compounds isolated from Vernonia cinerea.
Q46611038Biobehavioral modulation of the exosome transcriptome in ovarian carcinoma
Q38121858Biochemical and molecular mechanisms for the association between obesity, chronic inflammation, and breast cancer
Q37201984Biologic sequelae of I{kappa}B kinase (IKK) inhibition in multiple myeloma: therapeutic implications
Q104495231Biological and physical approaches on the role of piplartine (piperlongumine) in cancer
Q48640596Bioluminescence Imaging to Monitor the Effects of the Hsp90 Inhibitor NVP-AUY922 on NF-κB Pathway in Endometrial Cancer
Q39986163Bioluminescence imaging of hollow fibers in living animals: its application in monitoring molecular pathways
Q46374579Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb.
Q39652497Blocking NF-κB and Akt by Hsp90 inhibition sensitizes Smac mimetic compound 3-induced extrinsic apoptosis pathway and results in synergistic cancer cell death
Q35983857Blocking NF-κB: an inflammatory issue
Q35039902Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease
Q37291635Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells
Q38343228Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress
Q51118615Boswellia serrata resin extract alleviates azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colon tumorigenesis.
Q24293271Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA
Q40230617Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.
Q24304385Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis
Q39066460Breast tumor cell TACE-shed MCSF promotes pro-angiogenic macrophages through NF-κB signaling
Q35925490Brewers' rice modulates oxidative stress in azoxymethane-mediated colon carcinogenesis in rats.
Q64099847Burm. Methanol Extract Attenuates LPS-Induced Inflammatory Activities in Macrophage-Like RAW264.7 Cells
Q34304775C-reactive protein and ovarian cancer: a prospective study nested in three cohorts (Sweden, USA, Italy).
Q38877112C/EBPβ Mediates TNF-α-Induced Cancer Cell Migration by Inducing MMP Expression Dependent on p38 MAPK.
Q35541785CAPC negatively regulates NF-κB activation and suppresses tumor growth and metastasis
Q64279279CCL18 promotes the metastasis of squamous cell carcinoma of the head and neck through MTDH-NF-κB signalling pathway
Q38829381CCL18/PITPNM3 enhances migration, invasion, and EMT through the NF-κB signaling pathway in hepatocellular carcinoma
Q37249670CCR2 promotes hepatic fibrosis in mice
Q36751581CCR7 mediates inflammation-associated tumor progression
Q39437258CD73 represses pro-inflammatory responses in human endothelial cells
Q34533022CDA-2, a urinary preparation, inhibits lung cancer development through the suppression of NF-kappaB activation in myeloid cell
Q91618169CHUK/IKK-α loss in lung epithelial cells enhances NSCLC growth associated with HIF up-regulation
Q36922782CUEDC2: an emerging key player in inflammation and tumorigenesis
Q43981767CUX1 modulates polarization of tumor-associated macrophages by antagonizing NF-κB signaling.
Q26765342Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies
Q36587800Cancer and diet: How are they related?
Q33608038Cancer biology in diabetes
Q93116749Cancer cell-derived long pentraxin 3 (PTX3) promotes melanoma migration through a toll-like receptor 4 (TLR4)/NF-κB signaling pathway
Q37153407Cancer risk in immune-mediated inflammatory diseases (IMID).
Q33649230Cancer stem cell heterogeneity: origin and new perspectives on CSC targeting
Q64079366Cancer testis antigen 55 deficiency attenuates colitis-associated colorectal cancer by inhibiting NF-κB signaling
Q38728887Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation
Q39519626Candida virulence and ethanol-derived acetaldehyde production in oral cancer and non-cancer subjects
Q36358540Carbohydrate antigen 19-9 is a useful prognostic marker in esophagogastric junction adenocarcinoma
Q38976898Carbon disulfide. Just toxic or also bioregulatory and/or therapeutic?
Q50034271Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness.
Q99201955Carcinogenesis: Failure of resolution of inflammation?
Q36921618Caspase-9b Interacts Directly with cIAP1 to Drive Agonist-Independent Activation of NF-κB and Lung Tumorigenesis
Q92064508Cause and effect of microenvironmental acidosis on bone metastases
Q38853856Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway
Q41016182Celastrol inhibits migration and invasion through blocking the NF-κB pathway in ovarian cancer cells
Q41953684Cell Autonomous and Non-Autonomous Functions of IKKβ and NF-κB during the Pathogenesis of Gastrointestinal Tumors
Q36824518Cell-penetrating peptides: Possible transduction mechanisms and therapeutic applications
Q26800103Cell-type specific penetrating peptides: therapeutic promises and challenges
Q37959331Cellular and molecular mechanisms of autoimmune disease
Q37802043Cellular metabolic stress: considering how cells respond to nutrient excess.
Q24623979Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist
Q41142815Ceramide synthase-4 orchestrates the cell proliferation and tumor growth of liver cancer in vitro and in vivo through the nuclear factor-κB signaling pathway
Q88633612Cereblon suppresses the lipopolysaccharide-induced inflammatory response by promoting the ubiquitination and degradation of c-Jun
Q58696034Changes in gut microbiota and plasma inflammatory factors across the stages of colorectal tumorigenesis: a case-control study
Q38646941Characterization and assessment of potential microRNAs involved in phosphate-induced aortic calcification.
Q40264437Characterization of mechanisms involved in secretion of active heparanase
Q47634278Chelidonine inhibits TNF-α-induced inflammation by suppressing the NF-κB pathways in HCT116 cells.
Q37615916Chemical biology of inflammatory cytokine signaling
Q28822335Chemical metabolic inhibitors for the treatment of blood-borne cancers
Q35728558Chemokine receptor 7 (CCR7) gene expression is regulated by NF-κB and activator protein 1 (AP1) in metastatic squamous cell carcinoma of head and neck (SCCHN).
Q36752040Chemokines and squamous cancer of the head and neck: targets for therapeutic intervention?
Q46663854Chemoprevention by white currant is mediated by the reduction of nuclear beta-catenin and NF-kappaB levels in Min mice adenomas
Q37728618Chemoprevention of head and neck squamous cell carcinoma through inhibition of NF-κB signaling
Q35836432Chemopreventive effect of chalcone derivative, L2H17, in colon cancer development
Q53315978Chemopreventive effects of the standardized extract (DA-9601) of Artemisia asiatica on azoxymethane-initiated and dextran sulfate sodium-promoted mouse colon carcinogenesis.
Q36350221Chemosensitization of HepG2 cells by suppression of NF-κB/p65 gene transcription with specific-siRNA
Q35624238Chemotherapeutic properties of phospho-nonsteroidal anti-inflammatory drugs, a new class of anticancer compounds
Q42750382Chitinase-like proteins are autoantigens in a model of inflammation-promoted incipient neoplasia
Q37859424Chlamydial CT441 is a PDZ domain-containing tail-specific protease that interferes with the NF-kappaB pathway of immune response
Q38673438Chromosomal instability triggers cell death via local signalling through the innate immune receptor Toll
Q46489977Chronic Inflammation in Skin Malignancies
Q42590248Chronic NF-kappaB activation delays RasV12-induced premature senescence of human fibroblasts by suppressing the DNA damage checkpoint response.
Q99712023Chronic Stress Promotes Cancer Development
Q34079481Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonism
Q91936590Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles
Q48101725Chronic urinary tract infection and bladder carcinoma risk: a meta-analysis of case-control and cohort studies.
Q34222534Circadian disruption, Per3, and human cytokine secretion
Q37354561Circulating C-reactive protein and colorectal cancer risk: a report from the Shanghai Men's Health Study
Q35918276Circulating Inflammatory Mediators as Potential Prognostic Markers of Human Colorectal Cancer
Q36536034Circulating and tumor-infiltrating mucosal associated invariant T (MAIT) cells in colorectal cancer patients
Q41604995Circulating tumor cell interactions with macrophages: implications for biology and treatment
Q53651858Circulating tumor necrosis factor-α and YKL-40 level is associated with remission status following salvage therapy in relapsed non-Hodgkin lymphoma.
Q40205251Clathrin complexes with the inhibitor kappa B kinase signalosome: imaging the interactome
Q50916755Clinical and genetic factors associated with venous thromboembolism in myeloma patients treated with lenalidomide-based regimens.
Q35478306Clinical response to Auron Misheil Therapy in a man with advanced multifocal hepatocellular carcinoma: A case report
Q42003261Clock gene Per2 as a controller of liver carcinogenesis
Q37728405Cloning and characterization of DULP, a novel ubiquitin-like molecule from human dendritic cells
Q39038239Co-culture with NK-92MI cells enhanced the anti-cancer effect of bee venom on NSCLC cells by inactivation of NF-κB.
Q41143599Co-expression of β-arrestin1 and NF-кB is associated with cancer progression and poor prognosis in lung adenocarcinoma
Q38199426Coffee and cancer risk, epidemiological evidence, and molecular mechanisms
Q50561428Coffee, broccoli and spices are strong inducers of electrophile response element‐dependent transcription in vitro and in vivo – Studies in electrophile response element transgenic mice
Q35247738Color-coded imaging of splenocyte-pancreatic cancer cell interactions in the tumor microenvironment
Q42716078Colorectal carcinoma masked by systemic inflammatory response syndrome: A case report
Q52960400Combination therapy with human umbilical cord mesenchymal stem cells and angiotensin-converting enzyme 2 is superior for the treatment of acute lung ischemia-reperfusion injury in rats.
Q37906730Combinatorial strategies employing nutraceuticals for cancer development
Q39651374Combined activity of oridonin and wogonin in advanced-stage ovarian cancer cells: sensitivity of ovarian cancer cells to phyto-active chemicals
Q36480910Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer
Q39251309Combined effect of dehydroxymethylepoxyquinomicin and gemcitabine in a mouse model of liver metastasis of pancreatic cancer
Q42204382Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress
Q37169890Common Genetic Polymorphisms within NFκB-Related Genes and the Risk of Developing Invasive Aspergillosis
Q40105919Common effector processing mediates cell-specific responses to stimuli
Q53176277Comparative Effects of Curcumin and Tetrahydrocurcumin on Dextran Sulfate Sodium-induced Colitis and Inflammatory Signaling in Mice.
Q58063928Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and -negative gastric MALT lymphomas reveal both unique and overlapping gene programs
Q33779529Comparative genomics RNAi screen identifies Eftud2 as a novel regulator of innate immunity
Q37290391Comprehensive evaluation of a novel nuclear factor-kappaB inhibitor, quinoclamine, by transcriptomic analysis
Q35018212Computational modeling of mammalian signaling networks
Q36388394Concise review: Cancer stem cells and minimal residual disease
Q42747071Concurrent sulforaphane and eugenol induces differential effects on human cervical cancer cells
Q33968131Conditional ablation of Ikkb inhibits melanoma tumor development in mice
Q36336969Conditional deletion of Stat3 in mammary epithelium impairs the acute phase response and modulates immune cell numbers during post-lactational regression
Q41778161Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo
Q38985389Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151.
Q34708248Control of the inflammatory response mechanisms mediated by natural and induced regulatory T-cells in HCV-, HTLV-1-, and EBV-associated cancers
Q28512993Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways
Q34509419Coordinated binding of NF-kappaB family members in the response of human cells to lipopolysaccharide.
Q24307551Copine-I represses NF-kappaB transcription by endoproteolysis of p65
Q36493235Correlation between mimecan expression and coronary artery stenosis in patients with coronary heart disease
Q35156115Correlation of microRNA-16, microRNA-21 and microRNA-101 expression with cyclooxygenase-2 expression and angiogenic factors in cirrhotic and noncirrhotic human hepatocellular carcinoma
Q39547330Counteracting effect of TRPC1-associated Ca2+ influx on TNF-α-induced COX-2-dependent prostaglandin E2 production in human colonic myofibroblasts
Q48209599Critical cholangiocarcinogenesis control by cryptochrome clock genes
Q92926171Crosstalk between cancer and immune cells: Role of tumor-associated macrophages in the tumor microenvironment
Q36691086Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.
Q37736505Crosstalk between signals initiated from TLR4 and cell surface BAFF results in synergistic induction of proinflammatory mediators in THP-1 cells
Q42586119Crotamine stimulates phagocytic activity by inducing nitric oxide and TNF-α via p38 and NFκ-B signaling in RAW 264.7 macrophages
Q34328887Cryptopleurine targets NF-κB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis
Q54386411Cucurbitacin B suppresses the transactivation activity of RelA/p65.
Q39202485Cucurbitacin E exhibits anti-inflammatory effect in RAW 264.7 cells via suppression of NF-κB nuclear translocation.
Q35108012Cucurbitacin IIb exhibits anti-inflammatory activity through modulating multiple cellular behaviors of mouse lymphocytes
Q36012401Curcumin attenuates gastric cancer induced by N-methyl-N-nitrosourea and saturated sodium chloride in rats
Q38636412Curcumin prevents reperfusion injury following ischemic stroke in rats via inhibition of NF‑κB, ICAM-1, MMP-9 and caspase-3 expression
Q28393316Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment
Q28261784Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis
Q35224208Cyclophilin A (CypA) interacts with NF-κB subunit, p65/RelA, and contributes to NF-κB activation signaling
Q36960346Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates
Q28308101Cysteinyl leukotrienes and their receptors: bridging inflammation and colorectal cancer
Q35626872Cytokine induction of tumor necrosis factor receptor 2 is mediated by STAT3 in colon cancer cells
Q33358117Cytokine plasma levels: reliable predictors for radiation pneumonitis?
Q34542117Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma
Q53544015Cytosolic Hsp60 orchestrates the survival and inflammatory responses of vascular smooth muscle cells in injured aortic vessels.
Q58784334D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation
Q37535386DAMPs and inflammatory processes: the role of redox in the different outcomes
Q36296488DMA(V) in Drinking Water Activated NF-κB Signal Pathway and Increased TGF-β and IL-1β Expressions in Bladder Epithelial Cells of Rats
Q39944664DNA methyltransferase 3B mutant in ICF syndrome interacts non-covalently with SUMO-1.
Q36960228DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways
Q28267996Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer
Q53257548Death-associated protein kinase controls STAT3 activity in intestinal epithelial cells.
Q26826876Dedifferentiation and reprogramming: origins of cancer stem cells
Q28507762Deletion of Fanca or Fancd2 dysregulates Treg in mice
Q39925925Delphinidin, a dietary anthocyanidin in pigmented fruits and vegetables: a new weapon to blunt prostate cancer growth
Q38091116Dendritic cell tumor killing activity and its potential applications in cancer immunotherapy
Q38952158Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Q34212591Deregulated inflammasome signaling in disease
Q24648025Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer
Q35742808Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents.
Q40158562Detection and a possible link between parvovirus B19 and thyroid cancer.
Q55113244Detection of a lipid peroxidation-induced DNA adduct across liver disease stages.
Q38700300Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), an anticancer agent, exerts an anti-inflammatory effect in activated human mast cells
Q36529779Dichotomies in cancer research: some suggestions for a new synthesis
Q39937068Dichotomous metabolism of Enterococcus faecalis induced by haematin starvation modulates colonic gene expression
Q33758929Diet components can suppress inflammation and reduce cancer risk
Q36131792Dietary Glucosinolates Sulforaphane, Phenethyl Isothiocyanate, Indole-3-Carbinol/3,3'-Diindolylmethane: Anti-Oxidative Stress/Inflammation, Nrf2, Epigenetics/Epigenomics and In Vivo Cancer Chemopreventive Efficacy
Q90387094Dietary Inflammatory Index and Site-Specific Cancer Risk: A Systematic Review and Dose-Response  Meta-Analysis
Q90193038Dietary Polyacetylenic Oxylipins Falcarinol and Falcarindiol Prevent Inflammation and Colorectal Neoplastic Transformation: A Mechanistic and Dose-Response Study in A Rat Model
Q37370591Dietary docosahexaenoic and eicosapentaenoic acid: emerging mediators of inflammation.
Q37095276Dietary fiber is associated with circulating concentrations of C-reactive protein in breast cancer survivors: the HEAL study
Q58793547Dietary phytochemicals in breast cancer research: anticancer effects and potential utility for effective chemoprevention
Q48236727Dietary polyacetylenes, falcarinol and falcarindiol, isolated from carrots prevents the formation of neoplastic lesions in the colon of azoxymethane-induced rats
Q34241444Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature
Q34766399Differential activation of NF-κB and nitric oxide in lymphocytes regulates in vitro and in vivo radiosensitivity
Q33864180Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols
Q21135494Differential expression of microRNAs in tumors from chronically inflamed or genetic (APC(Min/+)) models of colon cancer
Q39653034Differential expression of mucins in Middle Eastern patients with colorectal cancer
Q34750616Differential gene expression profiling of gastric intraepithelial neoplasia and early-stage adenocarcinoma
Q90643299Differential impact of classical and non-canonical NF-κB pathway-related gene expression on the survival of breast cancer patients
Q41965715Differential requirements for IKKalpha and IKKbeta in the differentiation of primary human osteoarthritic chondrocytes.
Q39338015Dihydromyricetin suppresses TNF-α-induced NF-κB activation and target gene expression
Q37855820Direct Rel/NF-κB inhibitors: structural basis for mechanism of action
Q34255576Disruption of microtubules sensitizes the DNA damage-induced apoptosis through inhibiting nuclear factor κB (NF-κB) DNA-binding activity
Q47138550Dissecting cellular senescence and SASP in Drosophila
Q26783559Dissecting the Potential Interplay of DEK Functions in Inflammation and Cancer
Q36464593Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4⁺ T cells from patients with GI malignancy
Q37890981Does absolute neutrophil count predict high tumor grade in African-American men with prostate cancer?
Q34176503Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers.
Q39509449Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state
Q38940255Down-regulation of testes-specific protease 50 induces apoptosis in human laryngocarcinoma HEp2 cells in a NF-κB-mediated pathway
Q34542594Downregulation of TRAF2 mediates NIK-induced pancreatic cancer cell proliferation and tumorigenicity
Q47146670Downregulation of miR-141-3p promotes bone metastasis via activating NF-κB signaling in prostate cancer
Q39119385Doxorubicin induces atypical NF-κB activation through c-Abl kinase activity in breast cancer cells
Q35964572Doxycycline Promotes Carcinogenesis & Metastasis via Chronic Inflammatory Pathway: An In Vivo Approach
Q38017594Driving transcriptional regulators in melanoma metastasis
Q91846149Dual TBK1/IKKɛ inhibitor amlexanox attenuates the severity of hepatotoxin-induced liver fibrosis and biliary fibrosis in mice
Q33815901Dual effects of ouabain on the regulation of proliferation and apoptosis in human umbilical vein endothelial cells: involvement of Na(+)-K(+)-ATPase α-subunits and NF-κB.
Q54309191Dynamic activation of the key pathways: linking colitis to colorectal cancer in a mouse model.
Q33754562Dynamic, Large-Scale Profiling of Transcription Factor Activity from Live Cells in 3D Culture
Q37274623Dysregulated molecular networks in head and neck carcinogenesis
Q39794252Dysregulation of hepatocyte cell cycle and cell viability by hepatitis B virus
Q27000278E-cadherin and gastric cancer: cause, consequence, and applications
Q57369632E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury
Q37589139EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-κB activity
Q28397459Early life environment and developmental immunotoxicity in inflammatory dysfunction and disease
Q41130171Ebselen abrogates TNFalpha induced pro-inflammatory response in glioblastoma.
Q40010639Ectodomain shedding of TNF receptor 1 induced by protein synthesis inhibitors regulates TNF-alpha-mediated activation of NF-kappaB and caspase-8.
Q94528302Ectopic Expression of miR-532-3p Suppresses Bone Metastasis of Prostate Cancer Cells via Inactivating NF-κB Signaling
Q33885430Effect of dietary supplementation of procyanidin on growth performance and immune response in pigs
Q34735346Effect of hypoxic stress-activated Polo-like kinase 3 on corneal epithelial wound healing
Q55439924Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer.
Q92799604Effects of Dietary Inclusion of Shrimp Paste on Growth Performance, Digestive Enzymes Activities, Antioxidant and Immunological Status and Intestinal Morphology of Hybrid Snakehead (Channa maculata ♀ × Channa argus ♂)
Q34235551Effects of NFKB1 and NFKBIA gene polymorphisms on susceptibility to environmental factors and the clinicopathologic development of oral cancer
Q35418145Effects of a Chinese Herbal Medicine, Guan-Jen-Huang (Aeginetia indica Linn.), on Renal Cancer Cell Growth and Metastasis
Q43937010Effects of bovine lactoferrin on the immature porcine intestine.
Q35147800Effects of calorie restriction and diet-induced obesity on murine colon carcinogenesis, growth and inflammatory factors, and microRNA expression
Q52724794Effects of consumption of whole grape powder on basal NF-κB signaling and inflammatory cytokine secretion in a mouse model of inflammation.
Q42037601Effects of high mobility group protein box 1 and toll like receptor 4 pathway on warts caused by human papillomavirus
Q42459759Effects of temperature-humidity index and chromium supplementation on antioxidant capacity, heat shock protein 72, and cytokine responses of lactating cows
Q39304368Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial
Q45872155Efficacy of combining ING4 and TRAIL genes in cancer-targeting gene virotherapy strategy: First evidence in preclinical hepatocellular carcinoma
Q60934134Efp promotes in vitro and in vivo growth of endometrial cancer cells along with the activation of nuclear factor-κB signaling
Q26778011Eicosanoid pathway in colorectal cancer: Recent updates
Q42314594Elevated AEG-1 expression in macrophages promotes hypopharyngeal cancer invasion through the STAT3-MMP-9 signaling pathway
Q35828619Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling
Q37571441Elevated expression of TANK-binding kinase 1 enhances tamoxifen resistance in breast cancer
Q58423073Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer
Q38965233Embelin and Its Role in Chronic Diseases
Q34149945Embryonic stem cells and mammary luminal progenitors directly sense and respond to microbial products.
Q26824613Emerging role of Toll-like receptor 4 in hepatocellular carcinoma
Q35172778Emerging strategies for the early detection and prevention of head and neck squamous cell cancer
Q83402616Emerging therapies for multiple myeloma
Q37229916Endogenous damage-associated molecular pattern molecules at the crossroads of inflammation and cancer
Q38781958Endostatin inhibits the growth and migration of 4T1 mouse breast cancer cells by skewing macrophage polarity toward the M1 phenotype
Q42922612Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents
Q36252549Engagement of Components of DNA-Break Repair Complex and NFκB in Hsp70A1A Transcription Upregulation by Heat Shock
Q37684206Enhanced Anti-Cancer Effect of Snake Venom Activated NK Cells on Lung Cancer Cells by Inactivation of NF-κB
Q37680172Enhanced myeloid differentiation factor 88 promotes tumor metastasis via induction of epithelial-mesenchymal transition in human hepatocellular carcinoma
Q37118186Enhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines
Q30436566Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes
Q28388059Epigenetic changes induced by air toxics: formaldehyde exposure alters miRNA expression profiles in human lung cells
Q97653022Epigenetics in modulating immune functions of stromal and immune cells in the tumor microenvironment
Q59091394Epithelial NEMO links innate immunity to chronic intestinal inflammation
Q45942630Epithelial vanin-1 controls inflammation-driven carcinogenesis in the colitis-associated colon cancer model.
Q48146199Epithelial-Mesenchymal Transition in Pancreatic Cancer: A Review.
Q34595133Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer
Q35952706Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1
Q37672258Epithelium: the interplay between innate and Th2 immunity
Q35921787ErbB receptor tyrosine kinase/NF-κB signaling controls mammosphere formation in human breast cancer
Q24337661Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling
Q36877702Essential role of cooperative NF-κB and Stat3 recruitment to ICAM-1 intronic consensus elements in the regulation of radiation-induced invasion and migration in glioma
Q35920666Estrogen Protects against Obesity-Induced Mammary Gland Inflammation in Mice
Q33636941Estrogen receptor β induces antiinflammatory and antitumorigenic networks in colon cancer cells
Q35120661Ethanol extract of Poria cocos reduces the production of inflammatory mediators by suppressing the NF-kappaB signaling pathway in lipopolysaccharide-stimulated RAW 264.7 macrophages
Q35806083Evaluating Nuclear Factor NF-κB Activation following Bone Trauma: A Pilot Study in a Wistar Rats Model
Q38459602Evaluation of Prognostic Nutritional Index in Patients Undergoing Radical Surgery with Nonsmall Cell Lung Cancer
Q64066027Evaluation of the AGE/sRAGE Axis in Patients with Multiple Myeloma
Q35588508Evidence for induction of a tumor metastasis-receptive microenvironment for ovarian cancer cells in bone marrow and other organs as an unwanted and underestimated side effect of chemotherapy/radiotherapy
Q39735786Expression and regulation mechanisms of Sonic Hedgehog in breast cancer
Q34784913Expression and significance of HMGB1, TLR4 and NF-κB p65 in human epidermal tumors
Q33325701Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas
Q40150411Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling
Q39979306Expression of chemokines and chemokine receptors in human colon cancer
Q99711837Expression of p52, a non-canonical NF-kappaB transcription factor, is associated with poor ovarian cancer prognosis
Q35166851Expression of the inflammatory chemokines CCL2, CCL5 and CXCL2 and the receptors CCR1-3 and CXCR2 in T lymphocytes from mammary tumor-bearing mice
Q38932298Extracellular matrix and the myeloid-in-myeloma compartment: balancing tolerogenic and immunogenic inflammation in the myeloma niche
Q35781475Extracellular vesicles derived from renal cancer stem cells induce a pro-tumorigenic phenotype in mesenchymal stromal cells.
Q34853120Extract of Artemisia lavandulaefolia Inhibits In Vitro Angiogenesis in Human Umbilical Vein Endothelial Cells
Q91830768Extract of Makgeolli suldeot downregulates NF-κB-mediated MMP-9 expression, thereby inhibiting invasive activity in a human breast cancer cell line, MDA-MB-231
Q24300387FER tyrosine kinase (FER) overexpression mediates resistance to quinacrine through EGF-dependent activation of NF-kappaB
Q28586517Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response
Q36901888Fatigue is associated with inflammation in patients with head and neck cancer before and after intensity-modulated radiation therapy
Q38721869Ferulic acid suppresses expression of tryptophan metabolic key enzyme indoleamine 2, 3-dioxygenase via NFκB and p38 MAPK in lipopolysaccharide-stimulated microglial cells
Q51835187Fibroblast growth factor 1 ameliorates diabetic nephropathy by an anti-inflammatory mechanism.
Q37452775Fish oil suppresses cell growth and metastatic potential by regulating PTEN and NF-κB signaling in colorectal cancer
Q64938182Flavonoids: New Frontier for Immuno-Regulation and Breast Cancer Control.
Q39570966Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice
Q42183550Forkhead transcription factor FOXO3a protein activates nuclear factor κB through B-cell lymphoma/leukemia 10 (BCL10) protein and promotes tumor cell survival in serum deprivation
Q33665928Formation of 8-nitroguanine, a nitrative DNA lesion, in inflammation-related carcinogenesis and its significance
Q34650781Frequent engagement of RelB activation is critical for cell survival in multiple myeloma
Q59808913From Friend to Enemy: Dissecting the Functional Alteration of Immunoregulatory Components during Pancreatic Tumorigenesis
Q39192491Fucosterol inhibits matrix metalloproteinase expression and promotes type-1 procollagen production in UVB-induced HaCaT cells
Q27009399Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology
Q47709908Functional Toll-like receptor 4 expressed in lactotrophs mediates LPS-induced proliferation in experimental pituitary hyperplasia
Q35087443Functional and intracellular signaling differences associated with the Helicobacter pylori AlpAB adhesin from Western and East Asian strains
Q37866715Functional regulation of HIF-1α under normoxia--is there more than post-translational regulation?
Q39205404Functional roles of tumor necrosis factor-related apoptosis-inducing ligand-DR5 interaction in B16F10 cells by activating the nuclear factor-κB pathway to induce metastatic potential
Q37730952Functions of nuclear factor kappaB in bone
Q37293340G protein-coupled receptor connectivity to NF-kappaB in inflammation and cancer
Q90011228GIT1 regulates angiogenic factor secretion in bone marrow mesenchymal stem cells via NF-κB/Notch signalling to promote angiogenesis
Q52430611GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade.
Q28388105Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascades
Q38746805Galeterone and VNPT55 disrupt Mnk-eIF4E to inhibit prostate cancer cell migration and invasion
Q64891812Gastric carcinogenesis.
Q37559231Gastrokine 1 expression in the human gastric mucosa is closely associated with the degree of gastritis and DNA methylation
Q29614596Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
Q45989122Gender-specific association of NFKBIA promoter polymorphisms with the risk of sporadic colorectal cancer.
Q36652500Gene Expression Quantification of Toll like Receptors 2, 4 and Co-molecules in Human Glioblastoma Cell Line (U87-MG): Toward a New In vitro Model of Inflammation
Q26801146Genetic Association Between NFKBIA -881A>G Polymorphism and Cancer Susceptibility
Q88963822Genetic Modifiers of the Breast Tumor Microenvironment
Q24311010Genetic aspects of inflammation and cancer
Q36732083Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice
Q36622888Genetic polymorphisms in IL10RA and TNF modify the association between blood transfusion and risk of non-Hodgkin lymphoma
Q33641328Genetic susceptibility to lymphoma
Q35556219Genetic variation in inflammatory pathways is related to colorectal cancer survival
Q56558872Ginsenoside-Rg1 enhances angiogenesis and ameliorates ventricular remodeling in a rat model of myocardial infarction
Q54977208Glycogen synthase kinase-3β activity plays a key role in the antitumor effect of nafamostat mesilate in pancreatic cancer cells.
Q24336114Glycogen synthase kinase-3β is a crucial mediator of signal-induced RelB degradation
Q34606453Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis in the colon of Wistar rats
Q42779829Graph-based identification of cancer signaling pathways from published gene expression signatures using PubLiME
Q46750131Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model
Q39770321Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: involvement of cell cycle arrest and inactivation of nuclear factor-kappaB.
Q83737658Growth performance and immune responses in chickens after challenge with lipopolysaccharide and modulation by dietary different oils
Q38949434Gut Microbiota, Inflammation, and Colorectal Cancer.
Q26774708Gut microbiota imbalance and colorectal cancer
Q38190020H. pylori infection, inflammation and gastric cancer
Q91996454HBV-related hepatocarcinogenesis: the role of signalling pathways and innovative ex vivo research models
Q34618294HBx-induced NF-κB signaling in liver cells is potentially mediated by the ternary complex of HBx with p22-FLIP and NEMO.
Q80805979HDAC2 deficiency sensitizes colon cancer cells to TNFalpha-induced apoptosis through inhibition of NF-kappaB activity
Q42218400HPV16 E2-mediated potentiation of NF-κB activation induced by TNF-α involves parallel activation of STAT3 with a reduction in E2-induced apoptosis
Q28393960Health promoting effects of brassica-derived phytochemicals: from chemopreventive and anti-inflammatory activities to epigenetic regulation
Q35545513Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome
Q55266043Heat-stress-modulated induction of NF-κB leads to brucellacidal pro-inflammatory defense against Brucella abortus infection in murine macrophages and in a mouse model.
Q38194131Hedgehog signaling pathway as a new therapeutic target in pancreatic cancer
Q57753449Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment
Q26782813Helicobacter pylori and microRNAs: Relation with innate immunity and progression of preneoplastic conditions
Q38721526Helicobacter pylori inhibits the cleavage of TRAF1 via a CagA-dependent mechanism
Q42317062Helicteric Acid, Oleanic Acid, and Betulinic Acid, Three Triterpenes from Helicteres angustifolia L., Inhibit Proliferation and Induce Apoptosis in HT-29 Colorectal Cancer Cells via Suppressing NF-κB and STAT3 Signaling
Q40004886Heme oxygenase 1 controls early innate immune response of macrophages to Salmonella Typhimurium infection.
Q38116039Heparan sulfate inhibitors and their therapeutic implications in inflammatory illnesses
Q37983752Heparanase enzyme in chronic inflammatory bowel disease and colon cancer
Q34876266Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice
Q36545096Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis
Q39767815Hepatocellular carcinoma repression by TNFα-mediated synergistic lethal effect of mitosis defect-induced senescence and cell death sensitization.
Q87725770Hepatocyte nuclear factor 4α-nuclear factor-κB feedback circuit modulates liver cancer progression
Q33900418Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.
Q38607613Hes1 expression and CYLD repression are essential events downstream of Notch1 in T-cell leukemia.
Q39200116Heterozygous genetic variations of FOXP3 in Xp11.23 elevate breast cancer risk in Chinese population via skewed X-chromosome inactivation
Q28383878Hexavalent chromium Cr(VI) up-regulates COX-2 expression through an NFκB/c-Jun/AP-1-dependent pathway
Q35616490High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFκB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts
Q49787779High RAC3 expression levels are required for induction and maintaining of cancer cell stemness.
Q45345861High expression of Fibronectin 1 suppresses apoptosis through the NF-κB pathway and is associated with migration in nasopharyngeal carcinoma
Q43199306High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis
Q55307923High mobility group box 1 promotes the epithelial-to-mesenchymal transition in prostate cancer PC3 cells via the RAGE/NF-κB signaling pathway.
Q41071204High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells.
Q35531717High-Fat Diet-Induced Retinal Dysfunction
Q36175681High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases
Q33541291High-throughput and single-cell imaging of NF-kappaB oscillations using monoclonal cell lines
Q36602323High-throughput proteomics reveal alarmins as amplifiers of tissue pathology and inflammation after spinal cord injury
Q47161841Hispidulin-7-O-Neohesperidoside from Cirsium japonicum var. ussuriense Attenuates the Production of Inflammatory Mediators in LPS-Induced Raw 264.7 Cells and HT-29 Cells
Q24681342Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL
Q53184876Homeobox A9 directly targeted by miR-196b regulates aggressiveness through nuclear Factor-kappa B activity in non-small cell lung cancer cells.
Q34658467Host gene expression profiling and in vivo cytokine studies to characterize the role of linezolid and vancomycin in methicillin-resistant Staphylococcus aureus (MRSA) murine sepsis model
Q26745544How Mouse Macrophages Sense What Is Going On.
Q28505337Hsp70 inhibits lipopolysaccharide-induced NF-kappaB activation by interacting with TRAF6 and inhibiting its ubiquitination
Q39124267Hugl-1 induces apoptosis in esophageal carcinoma cells both in vitro and in vivo
Q37641275Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice
Q45388286Human T-cell leukemia virus type I tax down-regulates the expression of phosphatidylinositol 3,4,5-trisphosphate inositol phosphatases via the NF-kappaB pathway
Q38359794Human activated macrophages and hypoxia: a comprehensive review of the literature
Q33799921Human biliverdin reductase suppresses Goodpasture antigen-binding protein (GPBP) kinase activity: the reductase regulates tumor necrosis factor-alpha-NF-kappaB-dependent GPBP expression
Q61448596Human papilloma virus and breast cancer: the role of inflammation and viral expressed proteins
Q36216805Human papillomavirus genotypes in penile cancers from Japanese patients and HPV-induced NF-κB activation
Q39445934Human papillomavirus infection induces NF-κB activation in cervical cancer: A comparison with penile cancer
Q46015847Hyper-O-GlcNAcylation activates nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) signaling through interplay with phosphorylation and acetylation.
Q30540051Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells
Q36999112Hypoxic regulation of NF-kappaB signaling
Q24292870IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer
Q52687040ICAM3 mediates inflammatory signaling to promote cancer cell stemness.
Q40331218IKK alpha regulates estrogen-induced cell cycle progression by modulating E2F1 expression
Q24337225IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway
Q33776852IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity
Q33561833IKK/NF-kappaB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis
Q39840485IKKbeta-mediated nuclear factor-kappaB activation attenuates smac mimetic-induced apoptosis in cancer cells
Q50041873IKKα is required in the intestinal epithelial cells for tumour stemness.
Q53236646IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells.
Q38438570IKKα-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy
Q37688677IKKβ inhibitor in combination with bortezomib induces cytotoxicity in breast cancer cells
Q38256438IL-17 Expression by macrophages is associated with proliferative inflammatory atrophy lesions in prostate cancer patients
Q38873952IL-17C mediates the recruitment of tumor-associated neutrophils and lung tumor growth
Q36244747IL-1β-induced modulation of gene expression profile in human dermal fibroblasts: the effects of Thai herbal Sahatsatara formula, piperine and gallic acid possessing antioxidant properties
Q29614594IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
Q62761935INH14, a Small-Molecule Urea Derivative, Inhibits the IKKα/β-Dependent TLR Inflammatory Response
Q42269867IRAK4 turns IL-10+ phospho-FOXO+ monocytes into pro-inflammatory cells by suppression of protein kinase B.
Q64954349IRX5 promotes NF-κB signalling to increase proliferation, migration and invasion via OPN in tongue squamous cell carcinoma.
Q37691938ISG15 and immune diseases
Q99412585Icariin-induced inhibition of SIRT6/NF-κB triggers redox mediated apoptosis and enhances anti-tumor immunity in TNBC
Q39402421Id-1 and the p65 subunit of NF-κB promote migration of nasopharyngeal carcinoma cells and are correlated with poor prognosis.
Q40225454Id1 potentiates NF-kappaB activation upon T cell receptor signaling
Q38131077Identification of MFG-E8 as a novel therapeutic target for diseases
Q36984362Identification of TBK1 and IKKε, the non-canonical IκB kinases, as crucial pro-survival factors in HTLV-1-transformed T lymphocytes
Q38923475Identification of a ligand-induced transient refractory period in nuclear factor-kappaB signaling.
Q39659423Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis
Q64068609Identification of an immune signature predicting prognosis risk of patients in lung adenocarcinoma
Q41612750Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry.
Q90250087Identification of stable reference genes for lipopolysaccharide-stimulated macrophage gene expression studies
Q26823854Identifying novel spatiotemporal regulators of innate immunity
Q33294682IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway
Q33529490IkappaBalpha polymorphism at promoter region (rs2233408) influences the susceptibility of gastric cancer in Chinese
Q36715308Imbalanced network biomarkers for traditional Chinese medicine Syndrome in gastritis patients
Q40208275Immediate early gene-X1 interferes with 26 S proteasome activity by attenuating expression of the 19 S proteasomal components S5a/Rpn10 and S1/Rpn2.
Q92722005Immune senescence and immune activation in elderly colorectal cancer patients
Q37097545Immune surveillance: a balance between protumor and antitumor immunity
Q34025272Immunoglobulin responses at the mucosal interface.
Q36780699Immunoinflammatory mechanisms in lung cancer development: is leptin a mediator?
Q37974937Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment
Q41866274Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs: involvement of MAPK and NF-κB pathways
Q33750160Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor
Q46623243Immunosuppressive activity of alpinetin on activation and cytokines secretion of murine T lymphocytes
Q29636247Immunosuppressive strategies that are mediated by tumor cells
Q38068966Immunotherapy for head and neck cancer patients: shifting the balance
Q34049388Impact of tumour associated macrophages in pancreatic cancer.
Q35178414Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice
Q38088360Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part II: targeting cell cycle events, caspases, NF-κB and the proteasome.
Q64063487Importance of Incorporating Protein Flexibility in Molecule Modeling: A Theoretical Study on Type I NIK Inhibitors
Q46106564Improved Biocompatibility of Black Phosphorus Nanosheets by Chemical Modification
Q28476407In vitro and in vivo anti-inflammatory activity of 17-O-acetylacuminolide through the inhibition of cytokines, NF-κB translocation and IKKβ activity
Q38287065In vitro micro-physiological models for translational immunology
Q64055611In-depth characterization of the Wnt-signaling/β-catenin pathway in an in vitro model of Barrett's sequence
Q37104726Inactivation of FIP200 leads to inflammatory skin disorder, but not tumorigenesis, in conditional knock-out mouse models
Q36557300Inactivation of M2 AChR/NF-κB signaling axis reverses epithelial-mesenchymal transition (EMT) and suppresses migration and invasion in non-small cell lung cancer (NSCLC).
Q43081629Inciting inflammation: the RAGE about tumor promotion
Q39984492Increased cytotoxicity by the combination of radiation and diospyrin diethylether in fibrosarcoma in culture and in tumor
Q43747245Increased expression of TLR-2, COX-2, and SOD-2 genes in the peripheral blood leukocytes of opisthorchiasis patients induced by Opisthorchis viverrini antigen
Q34141506Increased frequency of Mediterranean fever gene variants in multiple myeloma
Q28478544Induction of Bcl-2 expression by hepatitis B virus pre-S2 mutant large surface protein resistance to 5-fluorouracil treatment in Huh-7 cells
Q37039724Induction of Chronic Inflammation and Altered Levels of DNA Hydroxymethylation in Somatic and Germinal Tissues of CBA/CaJ Mice Exposed to (48)Ti Ions
Q33900368Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-α.
Q42292361Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli
Q64120566Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol
Q33555975Infections and cancer: the "fifty shades of immunity" hypothesis
Q37668231Inflammation and EMT: an alliance towards organ fibrosis and cancer progression
Q92444112Inflammation and Oxidative Stress in Chronic Kidney Disease-Potential Therapeutic Role of Minerals, Vitamins and Plant-Derived Metabolites
Q36393268Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression
Q36393263Inflammation and breast cancer. Inflammatory component of mammary carcinogenesis in ErbB2 transgenic mice
Q36597803Inflammation and colorectal cancer: colitis-associated neoplasia
Q35091234Inflammation and increased aromatase expression occur in the breast tissue of obese women with breast cancer
Q24644807Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion
Q33653294Inflammation and oncogenesis: a vicious connection
Q27345379Inflammation and proliferation act together to mediate intestinal cell fusion
Q37250475Inflammation and stem cells in gastrointestinal carcinogenesis.
Q37232937Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4
Q38425458Inflammation in Parkinson's disease: role of glucocorticoids.
Q29620242Inflammation meets cancer, with NF-κB as the matchmaker
Q35024882Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
Q89998669Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
Q26749801Inflammatory and oxidative stress in rotavirus infection
Q44668087Inflammatory cells of immunosuppressive phenotypes in oral lichen planus have a proinflammatory pattern of expression and are associated with clinical parameters
Q36523752Inflammatory events during murine squamous cell carcinoma development.
Q37070898Influence of immunotherapy with autologous dendritic cells on innate and adaptive immune response in cancer.
Q28388503Inhalation of environmental stressors & chronic inflammation: autoimmunity and neurodegeneration
Q38516259Inherited variation in immune response genes in follicular lymphoma and diffuse large B-cell lymphoma
Q34205025Inhibiting NF-κB activation by small molecules as a therapeutic strategy
Q40102265Inhibiting TRAF2-mediated activation of NF-kappaB facilitates induction of AP-1.
Q58793793Inhibiting the CD8 T cell infiltration in the tumor microenvironment after radiotherapy is an important mechanism of radioresistance
Q41514229Inhibition of IKK-NFκB pathway sensitizes lung cancer cell lines to radiation
Q33270518Inhibition of NF-kappaB activation in vivo impairs establishment of gammaherpesvirus latency
Q34561763Inhibition of NF-κB activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis
Q47131486Inhibition of Pro-inflammatory and Anti-apoptotic Biomarkers during Experimental Oral Cancer Chemoprevention by Dietary Black Raspberries
Q40286294Inhibition of RelA phosphorylation sensitizes apoptosis in constitutive NF-kappaB-expressing and chemoresistant cells
Q36917707Inhibition of Soluble Tumor Necrosis Factor Prevents Chemically Induced Carcinogenesis in Mice
Q38906936Inhibition of canonical NF-κB nuclear localization by (-)-DHMEQ via impairment of DNA binding
Q39878770Inhibition of cyclin-dependent kinases by olomoucine and roscovitine reduces lipopolysaccharide-induced inflammatory responses via down-regulation of nuclear factor kappaB.
Q37848684Inhibition of histone deacetylases in inflammatory bowel diseases
Q39095137Inhibition of inflammatory mediators and reactive oxygen and nitrogen species by some depsidones and diaryl ether derivatives isolated from Corynespora cassiicola, an endophytic fungus of Gongronema latifolium leaves
Q35096709Inhibition of type 4 cyclic nucleotide phosphodiesterase blocks intracellular TLR signaling in chronic lymphocytic leukemia and normal hematopoietic cells.
Q34043446Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected]
Q26824586Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation
Q33953090Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity
Q41575754Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers
Q34754173Inhibitory effects of astaxanthin on azoxymethane-induced colonic preneoplastic lesions in C57/BL/KsJ-db/db mice
Q58552990Inhibitory effects of pentoxifylline on inflammation-related tumorigenesis in rat colon
Q57807665Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
Q34614189Innate signaling networks in mucosal IgA class switching
Q37994048Insulin-like growth factors and insulin: at the crossroad between tumor development and longevity
Q37305074Integrating computational and biochemical studies to explore mechanisms in NF-{kappa}B signaling
Q38084539Integrating dietary supplements into cancer care
Q99409494Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer
Q40055318Interferon-alpha induces transient upregulation of c-FLIP through NF-kappaB activation
Q34012857Interferon-β signaling contributes to Ras transformation
Q37081881Interleukin-1 regulates the expression of sphingosine kinase 1 in glioblastoma cells
Q38930857Interleukin-17 and interleukin-22 promote tumor progression in human nonmelanoma skin cancer.
Q60916226Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma
Q34989590Interplay between DNA repair and inflammation, and the link to cancer
Q24307391Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
Q37501316Investigations of the functional states of dendritic cells under different conditioned microenvironments by Fourier transformed infrared spectroscopy
Q33908674Involvement of NF-κB/IL-6 Pathway in the Processing of Colorectal Carcinogenesis in Colitis Mice
Q24315943Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation
Q53644644Ionizing radiation and leukaemia: more questions than answers.
Q79314692Ionizing radiation stimulates secretion of pro-inflammatory cytokines: dose-response relationship, mechanisms and implications
Q35223862Ionizing radiation, inflammation, and their interactions in colon carcinogenesis in Mlh1-deficient mice
Q28388335Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
Q24570128Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
Q39869217Iso-seco-tanapartholides: Isolation, Synthesis and Biological Evaluation.
Q64236794Isoalantolactone inhibits IKKβ kinase activity to interrupt the NF-κB/COX-2-mediated signaling cascade and induces apoptosis regulated by the mitochondrial translocation of cofilin in glioblastoma
Q35049534Itk: the rheostat of the T cell response
Q36397332IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation
Q46430962Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice.
Q37406535KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta
Q50283025KIND1 Loss Sensitizes Keratinocytes to UV-Induced Inflammatory Response and DNA Damage
Q34644229Kaposi Sarcoma Pathogenesis: A Triad of Viral Infection, Oncogenesis and Chronic Inflammation.
Q91742413Kin17 knockdown suppresses the migration and invasion of cervical cancer cells through NF-κB-Snail pathway
Q61816324Knockdown of PHF5A Inhibits Migration and Invasion of HCC Cells via Downregulating NF-B Signaling
Q36624048Knockout of phospholipase Cε attenuates N-butyl-N-(4-hydroxybutyl) nitrosamine-induced bladder tumorigenesis
Q36566015Krüppel-like factor-11, a transcription factor involved in diabetes mellitus, suppresses endothelial cell activation via the nuclear factor-κB signaling pathway.
Q37317234LGR5 expression is controled by IKKα in basal cell carcinoma through activating STAT3 signaling pathway
Q39695090LIGHT, a member of the TNF superfamily, activates Stat3 mediated by NIK pathway
Q36841546LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding
Q33838924LPS-induced cytokine levels are repressed by elevated expression of HSP70 in rats: possible role of NF-kappaB
Q61800291LUBAC determines chemotherapy resistance in squamous cell lung cancer
Q38855550LYG-202 exerts antitumor effect on PI3K/Akt signaling pathway in human breast cancer cells
Q46376244Leukotriene B4-receptor-1 mediated host response shapes gut microbiota and controls colon tumor progression
Q35034303Limiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicing
Q35042272Link between chronic inflammation and human papillomavirus-induced carcinogenesis (Review).
Q39849367Lipopolysaccharide-induced apoptosis in transformed bovine brain endothelial cells and human dermal microvessel endothelial cells: the role of JNK
Q36984127Localization of A20 to a lysosome-associated compartment and its role in NFkappaB signaling
Q51328387Long noncoding RNA-SRLR elicits intrinsic sorafenib resistance via evoking IL-6/STAT3 axis in renal cell carcinoma.
Q35947858Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.
Q30432425Loss of TFF1 is associated with activation of NF-κB-mediated inflammation and gastric neoplasia in mice and humans
Q41243646Loss of Tff1 Promotes Pro-Inflammatory Phenotype with Increase in the Levels of RORγt+ T Lymphocytes and Il-17 in Mouse Gastric Neoplasia
Q37276503Loss of estrogen-related receptor α promotes hepatocarcinogenesis development via metabolic and inflammatory disturbances.
Q34770928Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation
Q40521041Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
Q36386464Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokines
Q36526514Lower expression of activating transcription factors 3 and 4 correlates with shorter progression-free survival in multiple myeloma patients receiving bortezomib plus dexamethasone therapy
Q36891038Lung tumor NF-κB signaling promotes T cell-mediated immune surveillance
Q34080126Lupus serum IgG induces skin inflammation through the TNFR1 signaling pathway
Q24652632Luteolin, a flavonoid with potential for cancer prevention and therapy
Q34586289Lymphocyte deficiency limits Epstein-Barr virus latent membrane protein 1 induced chronic inflammation and carcinogenic pathology in vivo
Q27335708Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis
Q52682420Lysine methyltransferase SMYD2 promotes triple negative breast cancer progression.
Q35737634Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysis
Q34420804MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling
Q34700976MEKK3 expression correlates with nuclear factor kappa B activity and with expression of antiapoptotic genes in serous ovarian carcinoma
Q40009131MG132 proteasome inhibitor modulates proinflammatory cytokines production and expression of their receptors in U937 cells: involvement of nuclear factor-kappaB and activator protein-1.
Q26775996MPNs as Inflammatory Diseases: The Evidence, Consequences, and Perspectives
Q38946767Macrophage activation by polysaccharides from Atractylodes macrocephala Koidz through the nuclear factor-κB pathway
Q51209998Macrophage activation increases the invasive properties of hepatoma cells by destabilization of the adherens junction.
Q29615847Macrophage diversity enhances tumor progression and metastasis
Q54986341Macrophage inflammatory factors promote epithelial-mesenchymal transition in breast cancer.
Q28068581Macrophage migration inhibitory factor: a potential driver and biomarker for head and neck squamous cell carcinoma
Q37993741Macrophage polarization and plasticity in health and disease
Q36198192Macrophage-mediated lymphangiogenesis: the emerging role of macrophages as lymphatic endothelial progenitors
Q37955105Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands.
Q34507403Macrophages facilitate coal tar pitch extract-induced tumorigenic transformation of human bronchial epithelial cells mediated by NF-κB.
Q34329242Macrophages in multiple myeloma: emerging concepts and therapeutic implications
Q34824357Macrophages in the embryo and beyond: much more than just giant phagocytes.
Q83042337Magnetic Fe₃O₄ nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
Q35904209Mammary tissue microenvironment determines T cell-dependent breast cancer-associated inflammation
Q46307051Mapping normal and cancer cell signalling networks: towards single-cell proteomics
Q21146681Maternal undernutrition and cardiometabolic disease: a Latin American perspective
Q41576528Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development
Q36696163Matrix metalloproteinase-9 inhibition down-regulates radiation-induced nuclear factor-kappa B activity leading to apoptosis in breast tumors
Q41191469Matrix metalloproteinases and tissue inhibitor of metalloproteinases are essential for the inflammatory response in cancer cells
Q35886583Mechanisms and pathways of innate immune activation and regulation in health and cancer
Q37137367Mechanisms and therapeutic implications of cell death induction by indole compounds.
Q34494043Mechanisms by Which Pleiotropic Amphiphilic n-3 PUFA Reduce Colon Cancer Risk
Q37692380Mechanisms by which inflammation may increase intestinal cancer risk in inflammatory bowel disease
Q36898702Mechanisms of disease: chronic inflammation and cancer in the pancreas--a potential role for pancreatic stellate cells?
Q36490750Mechanisms of immune evasion by tumors
Q38088305Mechanisms of the joint-protective effects of p38 MAPK inhibitors in rodent arthritis
Q46081282Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation
Q89607086Mechanistic understanding of β-cryptoxanthin and lycopene in cancer prevention in animal models
Q39303608Melatonin MT1 receptor-induced transcriptional up-regulation of p27(Kip1) in prostate cancer antiproliferation is mediated via inhibition of constitutively active nuclear factor kappa B (NF-κB): potential implications on prostate cancer chemoprevent
Q28391500Menopausal hormone therapy and lung cancer-specific mortality following diagnosis: the California Teachers Study
Q37395883Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer
Q37053471Metallothionein 2A inhibits NF-κB pathway activation and predicts clinical outcome segregated with TNM stage in gastric cancer patients following radical resection
Q84098237Metastatic function of BMP-2 in gastric cancer cells: the role of PI3K/AKT, MAPK, the NF-κB pathway, and MMP-9 expression
Q39251789MiR-26a regulates cell cycle and anoikis of human esophageal adenocarcinoma cells through Rb1-E2F1 signaling pathway
Q50117508MiRNAs at the Crossroads between Innate Immunity and Cancer: Focus on Macrophages
Q24648543MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components
Q36090085MicroRNA-125b-5p suppresses Brucella abortus intracellular survival via control of A20 expression.
Q90733672MicroRNA-139-5p regulates chronic inflammation by suppressing nuclear factor-κB activity to inhibit cell proliferation and invasion in colorectal cancer
Q45854940MicroRNA-146b improves intestinal injury in mouse colitis by activating nuclear factor-κB and improving epithelial barrier function
Q38288067MicroRNA-181a-5p Impedes IL-17-Induced Nonsmall Cell Lung Cancer Proliferation and Migration through Targeting VCAM-1.
Q24289060MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11
Q35965465MicroRNA-7/NF-κB signaling regulatory feedback circuit regulates gastric carcinogenesis.
Q24630097MicroRNAs in NF-kappaB signaling
Q57300026Microbial Changes and Host Response in F344 Rat Colon Depending on Sex and Age Following a High-Fat Diet
Q55554558Microbiota, Epithelium, Inflammation, and TGF-β Signaling: An Intricate Interaction in Oncogenesis.
Q37273162Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms
Q51765947Mining the nucleus accumbens proteome for novel targets of alcohol self-administration in male C57BL/6J mice.
Q50785469Mitigation of Radiation-Induced Epithelial Damage by the TLR5 Agonist Entolimod in a Mouse Model of Fractionated Head and Neck Irradiation.
Q38544785Mitochondrial Ca(2+) Remodeling is a Prime Factor in Oncogenic Behavior
Q58556263Mitochondrial dysfunction in cancer
Q38064965Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease
Q40102576MnSOD protects colorectal cancer cells from TRAIL-induced apoptosis by inhibition of Smac/DIABLO release.
Q42705995Modulation of microRNA expression by volatile organic compounds in mouse lung
Q40224980Modulation of transcription factor NF-kappaB in Hodgkin's lymphoma cell lines: effect of (-)-epicatechin
Q92589397Molecular Mechanisms of Cancer-Induced Sleep Disruption
Q36803861Molecular analysis of the bovine anaphylatoxin C5a receptor
Q35740772Molecular damage in cancer: an argument for mTOR-driven aging
Q34384889Molecular marker identification for relapse prediction in 5-FU-based adjuvant chemotherapy in gastric and colorectal cancers
Q24655100Molecular mechanisms involved in farnesol-induced apoptosis
Q37605343Molecular mechanisms underlying chronic inflammation-associated cancers
Q30369661Molecular targets for anticancer redox chemotherapy and cisplatin-induced ototoxicity: the role of curcumin on pSTAT3 and Nrf-2 signalling.
Q37393034Monitoring the autophagy pathway in cancer
Q36167571Monocyte and macrophage plasticity in tissue repair and regeneration
Q90043574Monocytes and Macrophages in Cancer: Unsuspected Roles
Q37022872Monocytes mediate metastatic breast tumor cell adhesion to endothelium under flow
Q39402873Mountain ginseng extract exhibits anti-lung cancer activity by inhibiting the nuclear translocation of NF-κB.
Q24633765Mucins in cancer: function, prognosis and therapy
Q41919605Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Positively Modulates Matrix Metalloproteinase-9 Production in Alveolar Macrophages upon Toll-Like Receptor 7 Signaling and Influenza Virus Infection
Q28390894Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation
Q35890732Multiple Mechanisms of Anti-Cancer Effects Exerted by Astaxanthin
Q36973287Multiple endocrine neoplasia type 1 (MEN1) as a cancer predisposition syndrome: clues into the mechanisms of MEN1-related carcinogenesis
Q27008380Multiple roles of toll-like receptor 4 in colorectal cancer
Q39388171Multiplexed cytokine profiling of serum for detection of colorectal cancer
Q36544693Mutation of cysteine 46 in IKK-beta increases inflammatory responses
Q34768240Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation
Q50972710Myeloid TGF-β signaling contributes to colitis-associated tumorigenesis in mice.
Q39170190Myeloid cell RelA/p65 promotes lung cancer proliferation through Wnt/β-catenin signaling in murine and human tumor cells.
Q30412099Myeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors
Q42408323Myeloid cells in tumor inflammation
Q41978406Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation.
Q39104155Myeloid-derived suppressor cell function is reduced by Withaferin A, a potent and abundant component of Withania somnifera root extract
Q36718219NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions
Q53609454NF-kappaB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage.
Q46535142NF-kappaB activation by the viral oncoprotein StpC enhances IFN-gamma production in T cells
Q36725293NF-kappaB activation in development and progression of cancer
Q33744644NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia
Q34033879NF-kappaB balances vascular regression and angiogenesis via chromatin remodeling and NFAT displacement
Q37721657NF-kappaB fans the flames of lung carcinogenesis
Q37163422NF-kappaB in inflammatory bowel disease
Q28611413NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target
Q37480036NF-kappaB regulation: the nuclear response
Q37293337NF-kappaB signaling pathway and its therapeutic implications in human diseases
Q37701897NF-kappaB signaling: multiple angles to target OA.
Q36711178NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway.
Q33878632NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphoma
Q35900991NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis
Q50956905NF-κB Members Left Home: NF-κB-Independent Roles in Cancer.
Q36179538NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis
Q37374081NF-κB as a Target for Oncogenic Viruses
Q37981941NF-κB as a potential therapeutic target in microbial diseases
Q60301375NF-κB p65 and p105 implicate in interleukin 1β-mediated COX-2 expression in melanoma cells
Q37691276NF-κB signaling
Q49594691NF-κB, inflammation, immunity and cancer: coming of age.
Q35260971NF-κB-Mediated Regulation of Osteoclastogenesis
Q50112594NF-κB/miR-223-3p/ARID1A axis is involved in Helicobacter pylori CagA-induced gastric carcinogenesis and progression
Q35994472NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function
Q34285220NF-κB2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors
Q42411008NFX1 plays a role in human papillomavirus type 16 E6 activation of NFkappaB activity
Q93009350NFкB is a critical transcriptional regulator of atypical cadherin FAT1 in glioma
Q55457074NLRP3 promotes glioma cell proliferation and invasion via the interleukin-1β/NF-κB p65 signals.
Q37185879NO-donating aspirin inhibits the activation of NF-kappaB in human cancer cell lines and Min mice
Q33907548NOD-like receptors in intestinal homeostasis and epithelial tissue repair
Q33808220NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.
Q64981459NSE from diffuse large B-cell lymphoma cells regulates macrophage polarization.
Q89108705Naloxone attenuates ischemic brain injury in rats through suppressing the NIK/IKKα/NF-κB and neuronal apoptotic pathways
Q47363228Nanoparticle distribution during systemic inflammation is size-dependent and organ-specific
Q24298148Negative regulation of protein phosphatase 2Cbeta by ISG15 conjugation
Q36306990Nemo-like kinase (NLK) negatively regulates NF-kappa B activity through disrupting the interaction of TAK1 with IKKβ.
Q33575787Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes
Q28066130Neuraminidase-1: a novel therapeutic target in multistage tumorigenesis
Q36156573Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling
Q24612339Neutrophils responsive to endogenous IFN-beta regulate tumor angiogenesis and growth in a mouse tumor model
Q38810648New directions in poly(ADP-ribose) polymerase biology
Q38032236New insight into the oncogenic mechanism of the retroviral oncoprotein Tax.
Q36845724New technologies used in the study of human melanoma
Q37943790Next-generation treatment strategies for human papillomavirus-related head and neck squamous cell carcinoma: where do we go?
Q53341929Nickel compounds render anti-apoptotic effect to human bronchial epithelial Beas-2B cells by induction of cyclooxygenase-2 through an IKKbeta/p65-dependent and IKKalpha- and p50-independent pathway.
Q28389269Nickel-induced down-regulation of ΔNp63 and its role in the proliferation of keratinocytes
Q96952231Nitrative DNA damage in lung epithelial cells exposed to indium nanoparticles and indium ions
Q37710978Nitric oxide and calcium signaling regulate myocardial tumor necrosis factor-α expression and cardiac function in sepsis
Q38875536Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome
Q36680965Non-hodgkin lymphoma and circulating markers of inflammation and adiposity in a nested case-control study: the multiethnic cohort
Q37840104Novel IkB kinase inhibitors for treatment of nuclear factor-kB-related diseases
Q34277985Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of macrophage migration inhibitory factor
Q40186974Novel insights into the cellular mechanisms of the anti-inflammatory effects of NF-kappaB essential modulator binding domain peptides
Q53111716Novel synthetic curcumin analogs as potent antiangiogenic agents in colorectal cancer.
Q36018005Nrf2 and NF-κB Signaling Pathways Contribute to Porphyra-334-Mediated Inhibition of UVA-Induced Inflammation in Skin Fibroblasts
Q34209307Nuclear Factor-κB modulates cellular glutathione and prevents oxidative stress in cancer cells
Q34303188Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein
Q79758484Nuclear bile acid receptor farnesoid X receptor meets nuclear factor-kappaB: new insights into hepatic inflammation
Q38196790Nuclear factor-kappa-B signaling in lung development and disease: one pathway, numerous functions
Q33648301Nuclear factor-kappaB (NF-kappaB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase
Q79320536Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions
Q37681941Nuclear factor-kappaB and tumor-associated macrophages
Q29547879Nuclear factor-kappaB in cancer development and progression
Q38838562Nucleotide-binding oligomerization domain 2 (NOD2) activation induces apoptosis of human oral squamous cell carcinoma cells
Q37307180Nutrients and risk of colon cancer
Q28079556Obesity and colorectal cancer: molecular features of adipose tissue
Q42076725Obesity promotes colonic stem cell expansion during cancer initiation
Q64057162Obesity, DNA Damage, and Development of Obesity-Related Diseases
Q37325202Olfactomedin 4 deletion induces colon adenocarcinoma in Apc(Min/+) mice
Q39579099Oligomannurarate sulfate sensitizes cancer cells to doxorubicin by inhibiting atypical activation of NF-κB via targeting of Mre11.
Q39355041Oncogenic PI3K mutations lead to NF-κB-dependent cytokine expression following growth factor deprivation
Q40977712Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway.
Q36413217Opposed expression of IKKα: loss in keratinizing carcinomas and gain in non-keratinizing carcinomas
Q36937167Opposing functions of IKKbeta during acute and chronic intestinal inflammation
Q35945066Optical imaging of tumor cells in hollow fibers: evaluation of the antitumor activities of anticancer drugs and target validation
Q38089835Optical molecular imaging in drug discovery and clinical development
Q47330933Oral Cancer Stem Cells Microenvironment.
Q36543791Order, disorder, death: lessons from a superorganism
Q39285343Oroxylin A prevents inflammation-related tumor through down-regulation of inflammatory gene expression by inhibiting NF-κB signaling
Q90400168Over-expression of nuclear factor-κB family genes and inflammatory molecules is related to chronic obstructive pulmonary disease
Q36982546Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.
Q35195028Overexpression of the human ZNF300 gene enhances growth and metastasis of cancer cells through activating NF-kB pathway
Q37729938Oxidative Stress: A New Target for Pancreatic Cancer Prognosis and Treatment
Q36039273Oxidative stress promotes myofibroblast differentiation and tumour spreading
Q41949753Oxymatrine reduces neuroinflammation in rat brain: A signaling pathway
Q99630289P21-Activated Kinase 1: Emerging biological functions and potential therapeutic targets in Cancer
Q42264428PD-L1+MDSCs are increased in HCC patients and induced by soluble factor in the tumor microenvironment.
Q37618064PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65
Q55007045PIAS3-mediated feedback loops promote chronic colitis-associated malignant transformation.
Q40244068PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress.
Q42378816PKCε phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation
Q38537351PLCε signaling in cancer
Q37021709PPARs Mediate Lipid Signaling in Inflammation and Cancer
Q34100984PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells.
Q39247664PTEN/MAPK pathways play a key role in platelet-activating factor-induced experimental pulmonary tumor metastasis
Q35091196Pattern of transcription factor activation in Helicobacter pylori-infected Mongolian gerbils
Q36548470Pattern recognition receptors: a contemporary view on liver diseases.
Q54645079Peering into the aftermath: JAKi rips STAT3 in cancer.
Q37543936Peptides genetically selected for NF-κB activation cooperate with oncogene Ras and model carcinogenic role of inflammation
Q36261424Perfluorooctanoic acid enhances colorectal cancer DLD-1 cells invasiveness through activating NF-κB mediated matrix metalloproteinase-2/-9 expression
Q24312920Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors
Q41878187Perspective: alpha-bugs, their microbial partners, and the link to colon cancer
Q38853680Pharmacological Modulation of Proton Channel Hv1 in Cancer Therapy: Future Perspectives.
Q35849330Pharmacological basis of the use of the root bark of Zizyphus nummularia Aubrev. (Rhamnaceae) as anti-inflammatory agent.
Q36125880Phenotypic MicroRNA Microarrays
Q47105970Phenotypic heterogeneity in modeling cancer evolution.
Q52804185Phosphanegold(I) thiolates, Ph3PAu[SC(OR)=NC 6H 4Me-4] for R = Me, Et and iPr, induce apoptosis, cell cycle arrest and inhibit cell invasion of HT-29 colon cancer cells through modulation of the nuclear factor-κB activation pathway and ubiquitinatio
Q37116334Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: a redox-dependent effect
Q47112561Phosphorylation at S153 as a Functional Switch of Phosphatidylethanolamine Binding Protein 1 in Cerebral Ischemia-Reperfusion Injury in Rats.
Q30425294Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1.
Q33456429Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation
Q36433070Phytochemicals of Aristolochia tagala and Curcuma caesia exert anticancer effect by tumor necrosis factor-α-mediated decrease in nuclear factor kappaB binding activity
Q28394743Piperlongumine inhibits lung tumor growth via inhibition of nuclear factor kappa B signaling pathway
Q38761817Plantamajoside Inhibits UVB and Advanced Glycation End Products-Induced MMP-1 Expression by Suppressing the MAPK and NF-κB Pathways in HaCaT Cells
Q55090047Plasmodium circumsporozoite protein suppresses the growth of A549 cells via inhibiting nuclear transcription factor κB.
Q45253920Platelet-activating factor enhances tumour metastasis via the reactive oxygen species-dependent protein kinase casein kinase 2-mediated nuclear factor-κB activation
Q37154190Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells
Q61807253Platelet-rich plasma plays an antibacterial, anti-inflammatory and cell proliferation-promoting role in an in vitro model for diabetic infected wounds
Q36808629Polarized immune responses differentially regulate cancer development
Q64935031Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor-conditioned macrophages.
Q28395397Polymorphisms in the CHIT1 gene: Associations with colorectal cancer
Q40751696Polymorphisms of NFκB1 and IκBα and Their Synergistic Effect on Nasopharyngeal Carcinoma Susceptibility
Q34084838Polymorphisms of peroxisome proliferator-activated receptors and survival of lung cancer and upper aero-digestive tract cancers.
Q64076444Positive Immuno-Modulation Following Radiofrequency Assisted Liver Resection in Hepatocellular Carcinoma
Q37524210Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity
Q37799995Potential of the dietary antioxidants resveratrol and curcumin in prevention and treatment of hematologic malignancies.
Q37944053Potential role of antioxidant food supplements, preservatives and colorants in the pathogenesis of allergy and asthma
Q34594807Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
Q39391684Potentiating the effects of radiotherapy in rectal cancer: the role of aspirin, statins and metformin as adjuncts to therapy.
Q34937087Pre-treatment of human umbilical cord-derived mesenchymal stem cells with interleukin-6 abolishes their growth-promoting effect on gastric cancer cells
Q85857629Predictive role of levels of soluble interleukin-2 receptor and C-reactive protein in selecting autologous PBSC transplantation for lymphoma
Q89931341Preoperative NLR for predicting survival rate after radical resection combined with adjuvant immunotherapy with CIK and postoperative chemotherapy in gastric cancer
Q37306894Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.
Q34630418Primary intraosseous squamous cell carcinoma arising in an odontogenic cyst: a clinicopathologic analysis of 116 reported cases
Q38980308Pro-angiogenic effects of MDM2 through HIF-1α and NF-κB mediated mechanisms in LNCaP prostate cancer cells
Q40004010Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-kappaB and MAPK signalling
Q34407019Profiling microRNAs in lung tissue from pigs infected with Actinobacillus pleuropneumoniae
Q38296730Profiling of promoter occupancy by the SND1 transcriptional coactivator identifies downstream glycerolipid metabolic genes involved in TNFα response in human hepatoma cells
Q61804254Prognostic value of multiple cytokine analysis in colorectal cancer: a systematic review
Q35346509Prognostic value, clinicopathologic features and diagnostic accuracy of interleukin-8 in colorectal cancer: a meta-analysis
Q35526008Programmable oligomers targeting 5'-GGGG-3' in the minor groove of DNA and NF-kappaB binding inhibition
Q34303405Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis
Q24658240Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells
Q35141643Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity
Q42750201Proteasome activity is required for the initiation of precancerous pancreatic lesions.
Q39510395Proteasome inhibition in myelodysplastic syndromes and acute myelogenous leukemia cell lines
Q89552854Protective Effect of Amygdalin on LPS-Induced Acute Lung Injury by Inhibiting NF-κB and NLRP3 Signaling Pathways
Q91670292Protective Role of Fecal Microbiota Transplantation on Colitis and Colitis-Associated Colon Cancer in Mice Is Associated With Treg Cells
Q88499139Protective and Therapeutic Effects of Engeletin on LPS-Induced Acute Lung Injury
Q34941380Protective effects of hypothalamic beta-endorphin neurons against alcohol-induced liver injuries and liver cancers in rat animal models
Q90243732Protein interaction disruption in cancer
Q53228203Proteome profiling of keratinocytes transforming to malignancy.
Q37247067Pursuing different 'TRADDes': TRADD signaling induced by TNF-receptor 1 and the Epstein-Barr virus oncoprotein LMP1.
Q43832946Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8.
Q48174470Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-κB Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-α and the Fas Ligand
Q35102969RAGE Signaling Significantly Impacts Tumorigenesis and Hepatic Tumor Growth in Murine Models of Colorectal Carcinoma
Q36502858RAGE signaling sustains inflammation and promotes tumor development
Q24658378RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis
Q36544139RASSF8 downregulation promotes lymphangiogenesis and metastasis in esophageal squamous cell carcinoma
Q40050346RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR.
Q54977091RIPK4 promotes bladder urothelial carcinoma cell aggressiveness by upregulating VEGF-A through the NF-κB pathway.
Q92221569RNA helicase p68 deploys β-catenin in regulating RelA/p65 gene expression: implications in colon cancer
Q39279441RNF11 modulates microglia activation through NF-κB signalling cascade
Q42117551Radiation-induced glioblastoma signaling cascade regulates viability, apoptosis and differentiation of neural stem cells (NSC).
Q43572477Rage signalling promotes intestinal tumourigenesis
Q33795121Real-time monitoring of nuclear factor kappaB activity in cultured cells and in animal models.
Q50716567Real-time studies of the progression of bacterial infections and immediate tissue responses in live animals.
Q34152899Recent insights into the role of NF-kappaB in ovarian carcinogenesis
Q37113463Receptor-drug interaction: europium employment for studying the biochemical pathway of g-protein-coupled receptor activation
Q36124088Reduction of inflammatory bowel disease-induced tumor development in IL-10 knockout mice with soluble epoxide hydrolase gene deficiency
Q39277317Regulation of Gastric Metaplasia, Dysplasia, and Neoplasia by Bone Morphogenetic Protein Signaling
Q36180432Regulation of IL-20 Expression by Estradiol through KMT2B-Mediated Epigenetic Modification
Q36483396Regulation of MyD88-dependent signaling events by S nitrosylation retards toll-like receptor signal transduction and initiation of acute-phase immune responses
Q28511500Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination
Q38298517Regulation of angiogenesis by aminoacyl-tRNA synthetases
Q45410310Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways
Q36999102Regulation of hypoxia-inducible factors during inflammation
Q37378324Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB.
Q28512135Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
Q36677304Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor
Q38948512Regulatory T Cells and Cancer: A Two-Sided Story
Q36534827Regulatory T cells and innate immune regulation in tumor immunity
Q37023880Regulatory potential for concerted modulation of Nrf2- and Nfkb1-mediated gene expression in inflammation and carcinogenesis
Q36217010Relationship among human papillomavirus infection, p16(INK4a), p53 and NF-κB activation in penile cancer from northern Thailand
Q35192591Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis
Q38217707Research progress in signalling pathway in diabetic nephropathy
Q40198109Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kappaB but is related to downregulation of initiator caspases and DR4.
Q47584718Response to TNF-α Is Increasing Along with the Progression in Barrett's Esophagus
Q90009252Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells
Q36324806Resveratrol Protects against Helicobacter pylori-Associated Gastritis by Combating Oxidative Stress
Q43162195Resveratrol and piceatannol inhibit iNOS expression and NF-kappaB activation in dextran sulfate sodium-induced mouse colitis
Q34058331Retracted: Plexin-B1 Activates NF-κB and IL-8 to Promote a Pro-Angiogenic Response in Endothelial Cells
Q26749322Review: the Contribution of both Nature and Nurture to Carcinogenesis and Progression in Solid Tumours
Q24324531Ro52-mediated monoubiquitination of IKK{beta} down-regulates NF-{kappa}B signalling
Q27312487Role for sumoylation in systemic inflammation and immune homeostasis in Drosophila larvae
Q52569931Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents.
Q42350897Role of bacteria in carcinogenesis, with special reference to carcinoma of the gallbladder.
Q36439041Role of chronic E. coli infection in the process of bladder cancer- an experimental study
Q64974753Role of epigenetics in transformation of inflammation into colorectal cancer.
Q38542147Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease
Q37710885Role of estrogen in hepatocellular carcinoma: is inflammation the key?
Q36303643Role of macrophage migration inhibitory factor in the regulatory T cell response of tumor-bearing mice
Q33750847Role of microRNAs in resveratrol-mediated mitigation of colitis-associated tumorigenesis in Apc(Min/+) mice
Q38041500Role of nuclear factor-ĸB in breast and colorectal cancer
Q92724115Role of the COP9 Signalosome (CSN) in Cardiovascular Diseases
Q38042019Role of the Helicobacter pylori-induced inflammatory response in the development of gastric cancer
Q28073131Role of the Microbiota in Colorectal Cancer: Updates on Microbial Associations and Therapeutic Implications
Q39914415Role of the nervous system in cancer metastasis.
Q47237527Roles of Heat Shock Proteins in Apoptosis, Oxidative Stress, Human Inflammatory Diseases, and Cancer
Q52722878Roles of NF-κB Signaling in the Regulation of miRNAs Impacting on Inflammation in Cancer.
Q92868309Roles of the hexosamine biosynthetic pathway and pentose phosphate pathway in bile acid-induced cancer development
Q34413441Roles of tumor suppressors in regulating tumor-associated inflammation
Q92725333S100A11 functions as novel oncogene in glioblastoma via S100A11/ANXA2/NF-κB positive feedback loop
Q37376360S100A4 drives non-small cell lung cancer invasion, associates with poor prognosis, and is effectively targeted by the FDA-approved anti-helminthic agent niclosamide
Q39814040S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis.
Q34802977S100A8/A9 activate key genes and pathways in colon tumor progression
Q37164343SAG-UPS attenuates proapoptotic SARM and Noxa to confer survival advantage to early hepatocellular carcinoma
Q35228761SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer
Q54485665SJSZ glycoprotein (38 kDa) modulates macrophage type 1/2-related factors at hepatocarcinogenic stage in N-nitrosodiethylamine-treated Balb/c.
Q50074498SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis
Q36771328STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy.
Q26998940STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer
Q37162367STAT3 in epithelial cells regulates inflammation and tumor progression to malignant state in colon.
Q29547203STATs in cancer inflammation and immunity: a leading role for STAT3
Q90874251Sam68 impedes the recovery of arterial injury by augmenting inflammatory response
Q39230324Santonin-related compound 2 inhibits the nuclear translocation of NF-κB subunit p65 by targeting cysteine 38 in TNF-α-induced NF-κB signaling pathway
Q47599401Sarcopenia is associated with an increased risk of advanced colorectal neoplasia
Q36478254Screening for the Key lncRNA Targets Associated With Metastasis of Renal Clear Cell Carcinoma
Q37687457Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells
Q33799457Secreted interleukin-1alpha induces a metastatic phenotype in pancreatic cancer by sustaining a constitutive activation of nuclear factor-kappaB
Q33329753Selection and characterization of anti-NF-kappaB p65 RNA aptamers
Q37626577Selective TBK1/IKKi dual inhibitors with anticancer potency
Q39029981Selective killing of lung cancer cells by miRNA-506 molecule through inhibiting NF-κB p65 to evoke reactive oxygen species generation and p53 activation
Q36966767Selectively targeting the toll-like receptor 9 (TLR9)--IRF 7 signaling pathway by polymer blend particles
Q37702727Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling
Q40006395Sequestration of NF-kappaB signaling complexes in lipid rafts contributes to repression of NF-kappaB in T lymphocytes under hyperthermia stress
Q39909557Sequestration of PDLIM2 in the cytoplasm of monocytic/macrophage cells is associated with adhesion and increased nuclear activity of NF-kappaB.
Q34130898Sharpin contributes to TNFα dependent NFκB activation and anti-apoptotic signalling in hepatocytes
Q36546794Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome
Q64119071Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication
Q40087723Signal responsiveness of IkappaB kinases is determined by Cdc37-assisted transient interaction with Hsp90.
Q36492439Signal transduction of inflammatory cytokines and tumor development
Q33755839Signaling pathways in cartilage repair
Q35606024Signatures of human regulatory T cells: an encounter with old friends and new players
Q36101233Significance of heparanase in cancer and inflammation
Q57788138Silence of Stomatin-Like Protein 2 Represses Migration and Invasion Ability of Human Liver Cancer Cells via Inhibiting the Nuclear Factor Kappa B (NF-κB) Pathway
Q39178106Silver-based nanoparticles induce apoptosis in human colon cancer cells mediated through p53.
Q93169465Simvastatin Nanoparticles Reduce Inflammation in LPS-Stimulated Alveolar Macrophages
Q35220630Single hind limb burn injury to mice alters nuclear factor-κB expression and [¹⁸F] 2-fluoro-2-deoxy-D-glucose uptake
Q34542388Single-cell and population NF-κB dynamic responses depend on lipopolysaccharide preparation
Q40355223Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation
Q36899787Sleep loss activates cellular inflammatory signaling
Q55214898Sleeping Beauty and the Microenvironment Enchantment: Microenvironmental Regulation of the Proliferation-Quiescence Decision in Normal Tissues and in Cancer Development.
Q35835217Snail interacts with Id2 in the regulation of TNF-α-induced cancer cell invasion and migration in OSCC.
Q33781020Social network ties and inflammation in U.S. adults with cancer
Q39712901Soluble HLA-G induces NF-kappaB activation in natural killer cells.
Q57044552Sorafenib inhibits caspase-1 expression through suppressing TLR4/stat3/SUMO1 pathway in hepatocellular carcinoma
Q27675967Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Q91666430Spliceosome protein Eftud2 promotes colitis-associated tumorigenesis by modulating inflammatory response of macrophage
Q36819933Src family kinases and lipid mediators in control of allergic inflammation
Q24321517Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
Q34624443Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation
Q37972656Stat3: linking inflammation to (gastrointestinal) tumourigenesis
Q33921803Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?
Q36889332Stress signaling in cancer.
Q40072016Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment
Q46544116Stromal signatures in endometrioid endometrial carcinomas.
Q90152398Studying the effects of several heat-inactivated bacteria on colon and breast cancer cells
Q89869413Subcellular western blotting of single cells
Q35021987Substrate cleavage profiling suggests a distinct function of Bacteroides fragilis metalloproteinases (fragilysin and metalloproteinase II) at the microbiome-inflammation-cancer interface
Q39254514Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens
Q50978979Succinamide derivatives of melampomagnolide B and their anti-cancer activities.
Q30449201Suicidal gene therapy in an NF-κB-controlled tumor environment as monitored by a secreted blood reporter
Q37497981Sulindac activates NF-κB signaling in colon cancer cells
Q36425868Sumoylation is tumor-suppressive and confers proliferative quiescence to hematopoietic progenitors in Drosophila melanogaster larvae
Q40188580Suppression of NF-kappaB and AP-1 activation in monocytic cells persistently infected with measles virus
Q35414780Survivin and IAP proteins in cell-death mechanisms
Q42050158Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1.
Q28396388Sustained proliferation in cancer: Mechanisms and novel therapeutic targets
Q33703901Synbindin in extracellular signal-regulated protein kinase spatial regulation and gastric cancer aggressiveness
Q36325314Syndecan-1 deficiency promotes tumor growth in a murine model of colitis-induced colon carcinoma
Q47787057Synergistic effect of baicalein, wogonin and oroxylin A mixture: multistep inhibition of the NF-κB signalling pathway contributes to an anti-inflammatory effect of Scutellaria root flavonoids.
Q37149856Systemic targeting inhibitor of kappaB kinase inhibits melanoma tumor growth
Q40082885TAK1 is required for TGF-beta 1-mediated regulation of matrix metalloproteinase-9 and metastasis.
Q35169027TAK1-TAB2 signaling contributes to bone destruction by breast carcinoma cells
Q36868764TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice
Q24316100TC1 (C8orf4) is upregulated by cellular stress and mediates heat shock response
Q38312850TC1(C8orf4) is upregulated by IL-1beta/TNF-alpha and enhances proliferation of human follicular dendritic cells
Q36659217TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets.
Q36108579TIMP-2 targets tumor-associated myeloid suppressor cells with effects in cancer immune dysfunction and angiogenesis
Q36850457TLR agonists: our best frenemy in cancer immunotherapy
Q28291637TLR signaling
Q37490923TLR4 polymorphisms and ageing: implications for the pathophysiology of age-related diseases
Q41391981TLR7 inhibition: A novel strategy for pancreatic cancer treatment?
Q28389414TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis
Q36121743TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice
Q34835806TNF-alpha-dependent loss of IKKbeta-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis
Q37678189TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion
Q34480157TNFalpha induces ABCA1 through NF-kappaB in macrophages and in phagocytes ingesting apoptotic cells
Q37769438TRAF-mediated regulation of immune and inflammatory responses
Q33794121TRAF2 is an NF-κB-activating oncogene in epithelial cancers.
Q40035477TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis
Q98568662TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα
Q24299200TRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancers
Q38668064TWEAK/Fn14 signaling in tumors
Q37315118Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer
Q27002288Targeted therapy for hepatocellular carcinoma: novel agents on the horizon
Q34067270Targeted tumor necrosis factor receptor I preligand assembly domain improves skin lesions in MRL/lpr mice
Q52372117Targeting IκappaB kinases for cancer therapy.
Q99594459Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study
Q37731951Targeting TLR/IL-1R signalling in human diseases.
Q38125500Targeting cancer stem cells with sulforaphane, a dietary component from broccoli and broccoli sprouts
Q39007389Targeting colon cancer cell NF-κB promotes an anti-tumour M1-like macrophage phenotype and inhibits peritoneal metastasis
Q36653657Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis
Q35155622Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer
Q38028572Targeting kinases for the treatment of inflammatory diseases
Q37415794Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma
Q37286190Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology
Q39438509Targeting radioresistant osteosarcoma cells with parthenolide
Q36547077Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect
Q40195204Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
Q33736691Targeting the tumor microenvironment
Q37274132Targeting the tumor microenvironment: from understanding pathways to effective clinical trials
Q30986775Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice
Q34961213Temporal patterns of fatigue predict pathologic response in patients treated with preoperative chemoradiation therapy for rectal cancer
Q36141554Th1/Th2 Differentiation and B Cell Function by the Atypical PKCs and Their Regulators
Q28275462The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice
Q64388001The BRUCE-ATR Signaling Axis Is Required for Accurate DNA Replication and Suppression of Liver Cancer Development
Q38162225The Chemokine CXCL8 in Carcinogenesis and Drug Response
Q28593201The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
Q37583280The Effects of Metformin on Obesity-Induced Dysfunctional Retinas
Q36029051The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis
Q37521523The Functional Haplotypes of CHRM3 Modulate mRNA Expression and Associate with Bladder Cancer among a Chinese Han Population in Kaohsiung City.
Q36363512The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling Pathway
Q35249092The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice
Q37374645The IKK-related kinases: from innate immunity to oncogenesis
Q28270208The IkappaB kinase - a bridge between inflammation and cancer
Q89658487The Impact of IL-6 and IL-10 Gene Polymorphisms in Diffuse Large B-Cell Lymphoma Risk and Overall Survival in an Arab Population: A Case-Control Study
Q99605605The Macrophages-Microbiota Interplay in Colorectal Cancer (CRC)-Related Inflammation: Prognostic and Therapeutic Significance
Q40500532The Met protooncogene is a transcriptional target of NF kappaB: implications for cell survival
Q96946162The MyD88 inhibitor TJ-M2010-2 suppresses proliferation, migration and invasion of breast cancer cells by regulating MyD88/GSK-3β and MyD88/NF-κB signalling pathways
Q36876973The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR.
Q34596902The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy
Q36386035The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease
Q28390083The NIEHS Superfund Research Program: 25 Years of Translational Research for Public Health
Q33717170The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer: a case-control study and gene expression analyses
Q52597305The New Frontier: the Intestinal Microbiome and Surgery.
Q28268422The Plasmodium circumsporozoite protein, a novel NF-κB inhibitor, suppresses the growth of SW480
Q35193883The Receptor for Advanced Glycation End-products (RAGE) protects pancreatic tumor cells against oxidative injury
Q37108929The Rho-activating CNF1 toxin from pathogenic E. coli: a risk factor for human cancer development?
Q38988591The Role of Indirubins in Inflammation and Associated Tumorigenesis.
Q27486618The Role of Infectious Agents in the Etiology of Ocular Adnexal Neoplasia
Q41500559The Role of Proinflammatory Pathways in the Pathogenesis of Colitis-Associated Colorectal Cancer.
Q26779929The Role of Reactive Oxygen Species in Myelofibrosis and Related Neoplasms
Q28073691The Roles of Mesenchymal Stromal/Stem Cells in Tumor Microenvironment Associated with Inflammation
Q39308380The TNF-α/ROS/HIF-1-induced upregulation of FoxMI expression promotes HCC proliferation and resistance to apoptosis
Q38779629The Upregulation of TRAF1 Induced by Helicobacter pylori Plays an Antiapoptotic Effect on the Infected Cells
Q38809044The achievement of ligand-functionalized organic/polymeric nanoparticles for treating multidrug resistant cancer
Q28242458The activity of hsp90 alpha promoter is regulated by NF-kappa B transcription factors
Q36990593The adaptive immune response to sporadic cancer
Q37067708The anti-arthritic and immune-modulatory effects of NHAG: a novel glucosamine analogue in adjuvant-induced arthritis.
Q35823298The anti-inflammatory TIPE2 is an inhibitor of the oncogenic Ras.
Q34128053The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis
Q27026813The association between type 2 diabetes mellitus and women cancer: the epidemiological evidences and putative mechanisms
Q34547396The association of Streptococcus bovis/gallolyticus with colorectal tumors: the nature and the underlying mechanisms of its etiological role
Q38115636The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders.
Q41897354The biologic importance of tumor-infiltrating lymphocytes
Q36666503The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer development
Q38129243The cytotoxic necrotizing factor 1 from E. coli: a janus toxin playing with cancer regulators.
Q37115437The dark side of a tumor suppressor: anti-apoptotic p53.
Q36835317The death domain-containing kinase RIP1 regulates p27(Kip1) levels through the PI3K-Akt-forkhead pathway
Q92462353The diverse mechanisms and anticancer potential of naphthoquinones
Q34392824The effect of sulindac, a non-steroidal anti-inflammatory drug, attenuates inflammation and fibrosis in a mouse model of chronic pancreatitis
Q26748927The emerging role of FTY720 (Fingolimod) in cancer treatment
Q35231687The functional role of reactive stroma in benign prostatic hyperplasia
Q35513535The generation of carcinogenic etheno-DNA adducts in the liver of patients with nonalcoholic fatty liver disease
Q40141624The host inflammatory response promotes liver metastasis by increasing tumor cell arrest and extravasation.
Q35857513The human cytomegalovirus virion possesses an activated casein kinase II that allows for the rapid phosphorylation of the inhibitor of NF-kappaB, IkappaBalpha
Q24318687The human homolog of the Drosophila headcase protein slows down cell division of head and neck cancer cells
Q34287452The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα
Q37262995The immunological contribution of NF-κB within the tumor microenvironment: a potential protective role of zinc as an anti-tumor agent.
Q38091503The impact of hypoxia on cell death pathways
Q33997838The impact of the use of COL-1492, a nonoxynol-9 vaginal gel, on the presence of cervical human papillomavirus in female sex workers
Q36508039The in vitro study of apoptosis in NB4 cell induced by citral
Q93106964The indole compound MA-35 attenuates tumorigenesis in an inflammation-induced colon cancer model
Q29616025The inflammasome NLRs in immunity, inflammation, and associated diseases
Q37396607The inflammatory microenvironment in epithelial ovarian cancer: a role for TLR4 and MyD88 and related proteins
Q37973270The inflammatory network in the gastrointestinal tumor microenvironment: lessons from mouse models
Q54215473The inhibitory effect of a novel polypeptide fraction from Arca subcrenata on cancer-related inflammation in human cervical cancer HeLa cells.
Q30248605The intestinal microbiome and surgical disease.
Q51540350The joint association of REST and NFKB1 polymorphisms on the risk of colorectal cancer.
Q38231122The molecular landscape of pediatric brain tumors in the next-generation sequencing era.
Q47813995The nuclear factor-kappa B pathway and response to treatment in breast cancer
Q26864149The pleiotropic effects of erythropoietin in infection and inflammation
Q36959905The proinflammatory myeloid cell receptor TREM-1 controls Kupffer cell activation and development of hepatocellular carcinoma
Q36945537The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease
Q95650650The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
Q37212720The receptor RAGE: Bridging inflammation and cancer
Q39865435The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma
Q33685419The regulatory logic of the NF-kappaB signaling system
Q38622386The role of chronic inflammation in the development of gastrointestinal cancers: reviewing cancer prevention with natural anti-inflammatory intervention
Q34920381The role of cytokines in breast cancer development and progression
Q33674221The role of dysregulated glucose metabolism in epithelial ovarian cancer
Q38211081The role of inflammation in gastric cancer
Q37834316The role of lipopolysaccharide/toll-like receptor 4 signaling in chronic liver diseases.
Q38280869The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts
Q39280466The role of tenascin-C in tissue injury and tumorigenesis
Q42371680The role of toll-like receptor 4 in tumor microenvironment
Q37400616The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism
Q35530917The synergistic repressive effect of NF-κB and JNK inhibitor on the clonogenic capacity of Jurkat leukemia cells
Q34264487The threonine protease activity of testes-specific protease 50 (TSP50) is essential for its function in cell proliferation
Q36328530The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).
Q34614516The transcription factor C/EBP-β mediates constitutive and LPS-inducible transcription of murine SerpinB2.
Q36946019The tumor microenvironment and its role in promoting tumor growth
Q37179521The tumor microenvironment: An irreplaceable element of tumor budding and epithelial-mesenchymal transition-mediated cancer metastasis
Q53338021The tumour microenvironment as a target for chemoprevention.
Q34947832The type III histone deacetylase Sirt1 protein suppresses p300-mediated histone H3 lysine 56 acetylation at Bclaf1 promoter to inhibit T cell activation
Q24314649The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling
Q39439223The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress
Q28509686The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation
Q24300863Theileria-induced constitutive IKK activation is independent of functional Hsp90
Q92689597Therapeutic Effect of Y-27632 on Tumorigenesis and Cisplatin-Induced Peripheral Sensory Loss through RhoA-NF-κB
Q42111707Therapeutic effect of a hydroxynaphthoquinone fraction on dextran sulfate sodium-induced ulcerative colitis
Q38249091Therapeutic microRNAs targeting the NF-kappa B signaling circuits of cancers
Q37851151Therapeutic targeting of tumor-stroma interactions.
Q47282821Thermodynamic Aspects and Reprogramming Cellular Energy Metabolism during the Fibrosis Process
Q34483693Thioredoxin-mediated negative autoregulation of peroxisome proliferator-activated receptor alpha transcriptional activity
Q53359242Timp3 loss accelerates tumour invasion and increases prostate inflammation in a mouse model of prostate cancer.
Q38204742Toad glandular secretions and skin extractions as anti-inflammatory and anticancer agents
Q30493047Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation
Q92463719Tobacco, air pollution, environmental carcinogenesis, and thoughts on conquering strategies of lung cancer
Q93080297Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods
Q89509415Toll-like Receptors from the Perspective of Cancer Treatment
Q37718417Toll-like receptor-5 agonist Entolimod broadens the therapeutic window of 5-fluorouracil by reducing its toxicity to normal tissues in mice
Q37340298Toll-like receptors and cancer
Q39023996Toll-like receptors and cutaneous melanoma
Q37051007Toll-like receptors and immune regulation: implications for cancer therapy
Q36898647Toll-like receptors in the brain and their potential roles in neuropathology.
Q24289511Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples
Q92618166Transcription coactivator p300 promotes inflammation by enhancing p65 subunit activation in type 2 diabetes nephropathy
Q33762000Transcription factor co-repressors in cancer biology: roles and targeting
Q44682175Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia
Q33258202Transglutaminase 2 mediates polymer formation of I-kappaBalpha through C-terminal glutamine cluster
Q33707936Transglutaminase regulation of cell function.
Q90683678Translationally controlled tumor protein affects colorectal cancer metastasis through the high mobility group box 1-dependent pathway
Q33755300Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance
Q34629999Trimodal color-fluorescence-polarization endoscopy aided by a tumor selective molecular probe accurately detects flat lesions in colitis-associated cancer
Q34631363Triptolide reverses hypoxia-induced epithelial-mesenchymal transition and stem-like features in pancreatic cancer by NF-κB downregulation
Q36796876Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.
Q38606460Tumor Microenvironment as a New Target for Tumor Immunotherapy of Polysaccharides
Q35408783Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant
Q33759698Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression
Q37762226Tumor immune therapy: lessons from infection and implications for cancer - can IL-7 help overcome immune inhibitory networks?
Q36896195Tumor immunoediting and immunosculpting pathways to cancer progression.
Q37832693Tumor microenvironment is multifaceted
Q39675750Tumor necrosis factor receptor-associated factor-6 and ribosomal S6 kinase intracellular pathways link the angiotensin II AT1 receptor to the phosphorylation and activation of the IkappaB kinase complex in vascular smooth muscle cells
Q41890825Tumor necrosis factor-α-induced a disintegrin and metalloprotease 10 increases apoptosis resistance in prostate cancer cells
Q36997144Tumor stress, cell death and the ensuing immune response.
Q39403895Tumor-Associated Macrophages as Target for Antitumor Therapy.
Q37930487Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer
Q37773280Tumor-associated macrophages as targets for tumor immunotherapy.
Q39367300Tumor-associated macrophages promote angiogenesis and lymphangiogenesis of gastric cancer
Q38105286Tumor-associated macrophages: functional diversity, clinical significance, and open questions
Q39087629Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progression
Q54998169Tumor-derived extracellular vesicles activate primary monocytes.
Q37774865Tumor-initiating and -propagating cells: cells that we would like to identify and control
Q92063581Tumor-neuroglia interaction promotes pancreatic cancer metastasis
Q37085136Tumour immunity: effector response to tumour and role of the microenvironment
Q58260579Tumour-associated macrophages secrete IL-6 and MCP-1 in head and neck squamous cell carcinoma tissue
Q40283143Two distinct ubiquitin-dependent mechanisms are involved in NF-kappaB p105 proteolysis
Q38616699Type I Interferon Supports Inducible Nitric Oxide Synthase in Murine Hepatoma Cells and Hepatocytes and during Experimental Acetaminophen-Induced Liver Damage
Q39497268UDCA slows down intestinal cell proliferation by inducing high and sustained ERK phosphorylation
Q36546697URGCP promotes non-small cell lung cancer invasiveness by activating the NF-κB-MMP-9 pathway.
Q39345375USP2a negatively regulates IL-1β- and virus-induced NF-κB activation by deubiquitinating TRAF6.
Q58759523USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication
Q36601000Ubiquitin and ubiquitin-like proteins in cancer pathogenesis
Q36996420Ubiquitin-like domain of IKKβ regulates osteoclastogenesis and osteolysis
Q42056720Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling.
Q38336119Ultraviolet B radiation activates NF-κB and induces iNOS expression in HR-1 hairless mouse skin: role of IκB kinase-β.
Q36989955Ultraviolet B regulation of transcription factor families: roles of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis
Q90726349Unmethylated CpG motif-containing genomic DNA fragment of Bacillus calmette-guerin promotes macrophage functions through TLR9-mediated activation of NF-κB and MAPKs signaling pathways
Q28389159Unraveling 50-Year-Old Clues Linking Neurodegeneration and Cancer to Cycad Toxins: Are microRNAs Common Mediators?
Q37765590Unravelling the complexity of cancer-immune system interplay
Q84992338Up-regulated myeloid-derived suppressor cell contributes to hepatocellular carcinoma development by impairing dendritic cell function
Q34411599Upregulation of glucose metabolism by NF-κB2/p52 mediates enzalutamide resistance in castration-resistant prostate cancer cells
Q37645486Ursolic acid, a natural pentacyclic triterpenoid, inhibits intracellular trafficking of proteins and induces accumulation of intercellular adhesion molecule-1 linked to high-mannose-type glycans in the endoplasmic reticulum
Q39409408Vascular endothelial growth factor-induced skin carcinogenesis depends on recruitment and alternative activation of macrophages
Q37712961Venom from Cuban Blue Scorpion has tumor activating effect in hepatocellular carcinoma
Q34774880Viral carcinogenesis: factors inducing DNA damage and virus integration
Q37952350Viral interference with innate immunity by preventing NF-κB activity
Q38137030Vitronectin--master controller or micromanager?
Q88621887Walnut phenolic extract inhibits nuclear factor kappaB signaling in intestinal epithelial cells, and ameliorates experimental colitis and colitis-associated colon cancer in mice
Q35847798Walterinnesia aegyptia venom combined with silica nanoparticles enhances the functioning of normal lymphocytes through PI3K/AKT, NFκB and ERK signaling.
Q50666588What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori
Q26827754When ubiquitin meets NF-κB: a trove for anti-cancer drug development
Q24680891Why cancer and inflammation?
Q26797301Why does obesity promote cancer? Epidemiology, biology, and open questions
Q37376262Wogonoside prevents colitis-associated colorectal carcinogenesis and colon cancer progression in inflammation-related microenvironment via inhibiting NF-κB activation through PI3K/Akt pathway
Q64949987Xanthatin inhibits STAT3 and NF-κB signalling by covalently binding to JAK and IKK kinases.
Q49406138Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKKβ/NF-κB signaling in mice
Q46728352Z-ligustilide ameliorated ultraviolet B-induced oxidative stress and inflammatory cytokine production in human keratinocytes through upregulation of Nrf2/HO-1 and suppression of NF-κB pathway
Q34462187Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression
Q36262572alpha-Lipoic acid modulates extracellular matrix and angiogenesis gene expression in non-healing wounds treated with hyperbaric oxygen therapy
Q89623393miR-125b and miR-223 Contribute to Inflammation by Targeting the Key Molecules of NFκB Pathway
Q36193546miR-146a controls the resolution of T cell responses in mice
Q89927111miR-146a rs2431697 identifies myeloproliferative neoplasm patients with higher secondary myelofibrosis progression risk
Q60915354miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα
Q37448131miR-221 promotes growth and invasion of hepatocellular carcinoma cells by constitutive activation of NFκB.
Q55340090miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling.
Q38847523miRNA in Macrophage Development and Function
Q35086852miRNA regulation of cytokine genes
Q38979891miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A.
Q50067509miR‑873 inhibits colorectal cancer cell proliferation by targeting TRAF5 and TAB1.
Q86900164microRNA and NF-kappa B
Q24647606p120-catenin mediates inflammatory responses in the skin
Q28242189p21-activated kinases in cancer
Q33303032p38 mitogen-activated protein kinase inhibition decreases TNFalpha secretion and protects against left ventricular remodeling in rats with myocardial ischemia
Q37479790rpL3 promotes the apoptosis of p53 mutated lung cancer cells by down-regulating CBS and NFκB upon 5-FU treatment
Q49235115α7 nicotinic acetylcholine receptor in tumor-associated macrophages inhibits colorectal cancer metastasis through the JAK2/STAT3 signaling pathway
Q35151060β-Cryptoxanthin supplementation prevents cigarette smoke-induced lung inflammation, oxidative damage, and squamous metaplasia in ferrets
Q64070916β-Hydroxy-β-methylbutyrate Suppresses NF-ĸB Activation and IL-6 Production in TE-1 Cancer Cells

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