| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1155/2011/297868 |
| P8608 | Fatcat ID | release_kqzbsbplxrhunn72ljccd6iqte |
| P932 | PMC publication ID | 3116522 |
| P698 | PubMed publication ID | 21747996 |
| P5875 | ResearchGate publication ID | 51484604 |
| P2093 | author name string | Constantine D Tsoukas | |
| Juris A Grasis | |||
| P2860 | cites work | Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck | Q22009540 |
| Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk. | Q46862843 | ||
| CD2-mediated activation of the Tec-family tyrosine kinase ITK is controlled by proline-rich stretch-4 of the CD2 cytoplasmic tail | Q47697832 | ||
| Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation | Q47713209 | ||
| Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. | Q47720762 | ||
| Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33. | Q47729153 | ||
| Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development | Q47837774 | ||
| Pleckstrin homology domains: a common fold with diverse functions | Q47910921 | ||
| Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk. | Q50930741 | ||
| The role of erk1 and erk2 in multiple stages of T cell development. | Q50954940 | ||
| Reduced airway hyperresponsiveness and tracheal responses during allergic asthma in mice lacking tyrosine kinase inducible T-cell kinase. | Q51221186 | ||
| Impaired T-cell development in the absence of Vav1 and Itk. | Q51960672 | ||
| The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells. | Q51980787 | ||
| A key role for Itk in both IFN gamma and IL-4 production by NKT cells. | Q51982865 | ||
| Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. | Q54113549 | ||
| CD2 signaling in T cells involves tyrosine phosphorylation and activation of the Tec family kinase, EMT/ITK/TSK. | Q54484029 | ||
| Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein | Q22253357 | ||
| A novel transcription factor, T-bet, directs Th1 lineage commitment | Q22253874 | ||
| RasGRP links T-cell receptor signaling to Ras | Q22254082 | ||
| Profound block in thymocyte development in mice lacking p56lck | Q24298882 | ||
| Orai1 is an essential pore subunit of the CRAC channel | Q24300383 | ||
| A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells | Q24302377 | ||
| Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein | Q24306798 | ||
| BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2 | Q24308348 | ||
| p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation | Q24311999 | ||
| Identification, cloning, and characterization of a novel human T-cell-specific tyrosine kinase located at the hematopoietin complex on chromosome 5q | Q24312923 | ||
| LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation | Q24315021 | ||
| Essential role for ZAP-70 in both positive and negative selection of thymocytes | Q24321424 | ||
| Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia | Q24532248 | ||
| Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells | Q24532793 | ||
| Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A | Q24534698 | ||
| A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor | Q24545663 | ||
| Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation | Q24550768 | ||
| RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation | Q24671707 | ||
| STIM1, an essential and conserved component of store-operated Ca2+ channel function | Q24678317 | ||
| Structural characterization of a proline-driven conformational switch within the Itk SH2 domain | Q27639877 | ||
| Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors | Q27643098 | ||
| Regulatory intramolecular association in a tyrosine kinase of the Tec family | Q27734282 | ||
| Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells | Q27860460 | ||
| Interaction of SLP adaptors with the SH2 domain of Tec family kinases | Q28137757 | ||
| Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes | Q28139516 | ||
| Essential role of LAT in T cell development | Q28141618 | ||
| Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex | Q28142028 | ||
| Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells | Q55870100 | ||
| LAT, the Linker for Activation of T Cells: A Bridge Between T Cell-Specific and General Signaling Pathways | Q56551925 | ||
| Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor | Q57185397 | ||
| Identification of Highly Expressed Genes in Peripheral Blood T Cells from Patients with Atopic Dermatitis | Q57273185 | ||
| The SH3 domain of Itk/Emt binds to proline-rich sequences in the cytoplasmic domain of the T cell costimulatory receptor CD28 | Q57754179 | ||
| PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes | Q58617364 | ||
| C57BL/6 mice are more susceptible to antigen-induced pulmonary eosinophilia than BALB/c mice, irrespective of systemic T helper 1/T helper 2 responses | Q73231985 | ||
| Requirement for the SLP-76 adaptor GADS in T cell development | Q73587877 | ||
| Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT | Q73808221 | ||
| Mutation of Tec family kinases alters T helper cell differentiation | Q77149828 | ||
| Tyrosine phosphorylation of the Wiskott-Aldrich syndrome protein by Lyn and Btk is regulated by CDC42 | Q77318009 | ||
| Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet | Q77476285 | ||
| IL-17 enhances IL-1beta-mediated CXCL-8 release from human airway smooth muscle cells | Q79451452 | ||
| T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity | Q79609622 | ||
| Subtle defects in pre-TCR signaling in the absence of the Tec kinase Itk | Q79912705 | ||
| Positive regulation of Itk PH domain function by soluble IP4 | Q80108134 | ||
| The related adaptors, adaptor in lymphocytes of unknown function X and Rlk/Itk-binding protein, have nonredundant functions in lymphocytes | Q80641728 | ||
| Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C theta | Q80967943 | ||
| Protein kinase C-theta critically regulates the proliferation and survival of pathogen-specific T cells in murine listeriosis | Q81022651 | ||
| Cutting edge: Itk-dependent signals required for CD4+ T cells to exert, but not gain, Th2 effector function | Q82878750 | ||
| Characterization of a novel interaction between transcription factor TFII-I and the inducible tyrosine kinase in T cells. | Q34460336 | ||
| Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin | Q34465675 | ||
| Cytokine modulators as novel therapies for asthma | Q34504025 | ||
| New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision | Q34547220 | ||
| ADAP-ting TCR signaling to integrins | Q34594450 | ||
| T-cell development and the CD4-CD8 lineage decision | Q34659128 | ||
| Disrupting the intermolecular self-association of Itk enhances T cell signaling | Q34731639 | ||
| WASp in immune-system organization and function | Q34810230 | ||
| ITK and IL-15 support two distinct subsets of CD8+ T cells | Q35033191 | ||
| The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways | Q35064957 | ||
| The role of Tec family kinases in T cell development and function | Q35076690 | ||
| Protein kinase C-theta (PKCtheta): it's all about location, location, location. | Q35096674 | ||
| Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis | Q35575245 | ||
| Tyrosine kinase inhibitors: a new approach for asthma | Q35692069 | ||
| T cell receptor signaling: beyond complex complexes | Q35745872 | ||
| SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK | Q35800290 | ||
| Vav1 acidic region tyrosine 174 is required for the formation of T cell receptor-induced microclusters and is essential in T cell development and activation | Q35810320 | ||
| GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells | Q35834668 | ||
| Antiviral immune responses in Itk-deficient mice. | Q35894892 | ||
| Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome | Q36002814 | ||
| Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development. | Q36024288 | ||
| Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk | Q36066700 | ||
| Tec family kinases in T lymphocyte development and function | Q36072443 | ||
| TEC-family kinases: regulators of T-helper-cell differentiation | Q36085610 | ||
| Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP. | Q36158629 | ||
| The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells | Q36229690 | ||
| Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk. | Q36368328 | ||
| Tec family kinases modulate thresholds for thymocyte development and selection | Q36368982 | ||
| Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways. | Q36370142 | ||
| Itk negatively regulates induction of T cell proliferation by CD28 costimulation | Q36380370 | ||
| T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells | Q36400875 | ||
| A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients | Q36402834 | ||
| Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment | Q36403025 | ||
| Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity | Q36501636 | ||
| Induction of T helper type 2 immunity by a point mutation in the LAT adaptor | Q44029002 | ||
| A LAT mutation that inhibits T cell development yet induces lymphoproliferation | Q44029004 | ||
| NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation | Q44113021 | ||
| SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site | Q44521269 | ||
| Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes. | Q44556255 | ||
| Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK. | Q44881122 | ||
| Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. | Q44894318 | ||
| Requirement for Tec kinases in chemokine-induced migration and activation of Cdc42 and Rac. | Q44928689 | ||
| The Tec29 tyrosine kinase is required during Drosophila embryogenesis and interacts with Src64 in ring canal development | Q44952044 | ||
| Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk. | Q45016183 | ||
| Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet | Q45042146 | ||
| Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter | Q46062240 | ||
| SRC64 regulates the localization of a Tec-family kinase required for Drosophila ring canal growth | Q46366177 | ||
| Interleukin-2-inducible T cell kinase regulates mast cell degranulation and acute allergic responses | Q46391287 | ||
| Itk is not essential for CD28 signaling in naive T cells | Q46425867 | ||
| Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction | Q46517603 | ||
| The influence of the MAPK pathway on T cell lineage commitment | Q46660975 | ||
| Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion | Q46763999 | ||
| Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade | Q28142714 | ||
| Tec kinases: a family with multiple roles in immunity | Q28143522 | ||
| Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment | Q28145381 | ||
| Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha) | Q28189725 | ||
| The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organization | Q28198756 | ||
| T cell receptor signaling precedes immunological synapse formation | Q28203073 | ||
| Characterization of Itk tyrosine kinase: contribution of noncatalytic domains to enzymatic activity | Q28204624 | ||
| SH2 domains, interaction modules and cellular wiring | Q28206773 | ||
| Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases | Q28207891 | ||
| LAT, the linker for activation of T cells: a bridge between T cell-specific and general signaling pathways | Q28213042 | ||
| The proline rich region of the Tec homology domain of ITK regulates its activity | Q28216946 | ||
| Transcription factors of the NFAT family: regulation and function | Q28237645 | ||
| Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity | Q28249985 | ||
| A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9 | Q28270715 | ||
| Human Txk: genomic organization, structure and contiguous physical linkage with the Tec gene | Q28279145 | ||
| Identification of Itk/Tsk Src homology 3 domain ligands | Q28290110 | ||
| SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond | Q28298645 | ||
| A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function | Q28305026 | ||
| Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity | Q28505061 | ||
| Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development | Q28511412 | ||
| Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity | Q28512312 | ||
| A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development | Q28589467 | ||
| RasGRP is essential for mouse thymocyte differentiation and TCR signaling | Q28589756 | ||
| Defective Fas ligand expression and activation-induced cell death in the absence of IL-2-inducible T cell kinase | Q28589905 | ||
| Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells | Q28590075 | ||
| Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension | Q28591494 | ||
| The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival | Q28592807 | ||
| Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses | Q28594762 | ||
| A new tyrosine phosphorylation site in PLC gamma 1: the role of tyrosine 775 in immune receptor signaling | Q28646434 | ||
| A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 | Q29547855 | ||
| Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages | Q29547871 | ||
| NF-kappaB: linking inflammation and immunity to cancer development and progression | Q29614597 | ||
| Structural basis of integrin regulation and signaling | Q29617618 | ||
| In vivo significance of ITK-SLP-76 interaction in cytokine production | Q30156865 | ||
| The Tec family kinase Itk exists as a folded monomer in vivo | Q30157151 | ||
| Inducible T cell tyrosine kinase (ITK): structural requirements and actin polymerization | Q36520324 | ||
| Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec | Q36572135 | ||
| Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase | Q36590074 | ||
| Selective targeting of ITK blocks multiple steps of HIV replication. | Q36627588 | ||
| Requirements for selection of conventional and innate T lymphocyte lineages | Q36648754 | ||
| Dynamic control of signaling by modular adaptor proteins | Q36743016 | ||
| Tec kinases in T cell and mast cell signaling | Q36769470 | ||
| Calcium signalling in lymphocyte activation and disease | Q36912139 | ||
| The Tec family kinase, IL-2-inducible T cell kinase, differentially controls mast cell responses | Q36974135 | ||
| Interleukin 2 plays a central role in Th2 differentiation. | Q37095134 | ||
| Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation | Q37170806 | ||
| Terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase | Q37177808 | ||
| Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo. | Q37208530 | ||
| SKAP-55, SKAP-55-related and ADAP adaptors modulate integrin-mediated immune-cell adhesion | Q37257440 | ||
| A protective function for interleukin 17A in T cell-mediated intestinal inflammation | Q37260173 | ||
| Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production | Q37268943 | ||
| itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2 | Q37312952 | ||
| Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase | Q37399188 | ||
| The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface | Q37419923 | ||
| Gene regulation mediated by calcium signals in T lymphocytes | Q38302789 | ||
| Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav | Q39451395 | ||
| Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. | Q39697358 | ||
| Differential regulation of human NK cell-mediated cytotoxicity by the tyrosine kinase Itk. | Q40162985 | ||
| Dual role of SLP-76 in mediating T cell receptor-induced activation of phospholipase C-gamma1. | Q40200375 | ||
| Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine | Q40425586 | ||
| The regulation of immunity to Leishmania major | Q40444839 | ||
| Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton. | Q40468294 | ||
| Selective Itk inhibitors block T-cell activation and murine lung inflammation | Q40523378 | ||
| Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP. | Q40585986 | ||
| Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells | Q40757721 | ||
| CD28 as a molecular amplifier extending TCR ligation and signaling capabilities. | Q40761126 | ||
| Interaction between the Btk PH domain and phosphatidylinositol-3,4,5-trisphosphate directly regulates Btk. | Q40816296 | ||
| Involvement of wiskott-aldrich syndrome protein in B-cell cytoplasmic tyrosine kinase pathway. | Q40968768 | ||
| Functional LCK Is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK. | Q41214304 | ||
| Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene | Q41358116 | ||
| Pleckstrin homology domains interact with filamentous actin | Q41676998 | ||
| Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells | Q41700451 | ||
| T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. | Q41791616 | ||
| WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells | Q41897453 | ||
| Differential sensitivity to Itk kinase signals for T helper 2 cytokine production and chemokine-mediated migration | Q41997870 | ||
| Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK. | Q42579107 | ||
| T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. | Q42742129 | ||
| Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76. | Q43152094 | ||
| Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction | Q43493690 | ||
| Identification of the minimal tyrosine residues required for linker for activation of T cell function | Q43632117 | ||
| Coupling of the TCR to integrin activation by Slap-130/Fyb. | Q43744923 | ||
| Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells | Q43930610 | ||
| The absence of Itk inhibits positive selection without changing lineage commitment | Q44021498 | ||
| Itk phosphorylation sites are required for functional activity in primary T cells | Q30164638 | ||
| Inducible T cell tyrosine kinase regulates actin-dependent cytoskeletal events induced by the T cell antigen receptor | Q30164783 | ||
| Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton | Q30167854 | ||
| The role of Gads in hematopoietic cell signalling. | Q30167860 | ||
| Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins. | Q30168128 | ||
| A specific intermolecular association between the regulatory domains of a Tec family kinase | Q30168752 | ||
| TCR/CD3-Induced activation and binding of Emt/Itk to linker of activated T cell complexes: requirement for the Src homology 2 domain. | Q30168948 | ||
| The SH3 domain of Bruton's tyrosine kinase displays altered ligand binding properties when auto-phosphorylated in vitro | Q30175389 | ||
| Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes | Q30193572 | ||
| Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav. | Q30193575 | ||
| Tec homology (TH) adjacent to the PH domain. | Q30194119 | ||
| Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells | Q30195063 | ||
| The Tec family protein-tyrosine kinases: a subset of kinases for a subset of signalings. | Q30326046 | ||
| CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line | Q30454003 | ||
| Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation. | Q30483548 | ||
| Involvement of LAT, Gads, and Grb2 in compartmentation of SLP-76 to the plasma membrane | Q30655329 | ||
| Emt/Itk associates with activated TCR complexes: role of the pleckstrin homology domain. | Q30816418 | ||
| Calcium signaling mechanisms in T lymphocytes | Q32186061 | ||
| Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation | Q33292130 | ||
| Structure and function of the Wiskott-Aldrich syndrome protein | Q33366576 | ||
| T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells | Q33543765 | ||
| A two-step process for cytokine production revealed by IL-4 dual-reporter mice | Q33677827 | ||
| rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases | Q33869434 | ||
| Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation | Q33890664 | ||
| Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits | Q33912431 | ||
| Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-gamma1. | Q33934437 | ||
| T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells | Q33952975 | ||
| Positive and negative selection of T cells | Q34157557 | ||
| Attenuation of Immunological Symptoms of Allergic Asthma in Mice Lacking the Tyrosine Kinase ITK | Q34195229 | ||
| Itk/Emt: a link between T cell antigen receptor-mediated Ca2+ events and cytoskeletal reorganization | Q34207511 | ||
| The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species | Q34243592 | ||
| Partners in transcription: NFAT and AP-1. | Q34279371 | ||
| Analysis of CD28 cytoplasmic tail tyrosine residues as regulators and substrates for the protein tyrosine kinases, EMT and LCK. | Q34413102 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P304 | page(s) | 297868 | |
| P577 | publication date | 2011-04-07 | |
| P1433 | published in | Journal of Signal Transduction | Q26841830 |
| P1476 | title | Itk: the rheostat of the T cell response | |
| P478 | volume | 2011 |
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| Q27684168 | Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy |
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| Q30009861 | Regulation of immune responsiveness in vivo by disrupting an early T-cell signaling event using a cell-permeable peptide |
| Q39970262 | Rescue of the aggregation prone Itk Pleckstrin Homology domain by two mutations derived from the related kinases, Btk and Tec. |
| Q57752422 | The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases |
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