Transglutaminase 2 mediates polymer formation of I-kappaBalpha through C-terminal glutamine cluster

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Transglutaminase 2 mediates polymer formation of I-kappaBalpha through C-terminal glutamine cluster is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M604150200
P698PubMed publication ID16987813
P5875ResearchGate publication ID247488292

P2093author name stringSung-Soo Park
Soo-Youl Kim
Dae-Seok Kim
In-Hoo Kim
Jung-Mo Kim
P2860cites workThe NF-kappa B and I kappa B proteins: new discoveries and insightsQ24313579
Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activationQ24316905
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaBQ24321775
IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complexQ24530641
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complexQ28145172
Transglutaminase 2 induces nuclear factor-kappaB activation via a novel pathway in BV-2 microgliaQ28582000
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesisQ29547538
NF-kappaB: linking inflammation and immunity to cancer development and progressionQ29614597
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylationQ29614709
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-betaQ29617188
Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa BQ29618210
Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignanciesQ33345317
NF-kappa B as a therapeutic target in multiple myelomaQ34521393
Novel transglutaminase inhibitors reverse the inflammation of allergic conjunctivitisQ34827307
Proteasome: an emerging target for cancer therapyQ36104401
Transglutaminase 2 in inflammationQ36486713
IkappaB kinase-independent IkappaBalpha degradation pathway: functional NF-kappaB activity and implications for cancer therapyQ40172372
Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell deathQ42441668
A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.Q45142085
High levels of transglutaminase expression in doxorubicin-resistant human breast carcinoma cellsQ46198386
Transglutaminases.Q53905767
Getting down to specificsQ59087821
P433issue46
P407language of work or nameEnglishQ1860
P304page(s)34965-34972
P577publication date2006-09-20
P1433published inJournal of Biological ChemistryQ867727
P1476titleTransglutaminase 2 mediates polymer formation of I-kappaBalpha through C-terminal glutamine cluster
P478volume281

Reverse relations

cites work (P2860)
Q39162858Anti-cancer effect of a quinoxaline derivative GK13 as a transglutaminase 2 inhibitor.
Q33817561Bcr is a substrate for Transglutaminase 2 cross-linking activity
Q24304987Cancer cells promote survival through depletion of the von Hippel-Lindau tumor suppressor by protein crosslinking
Q28249358Depletion of cathepsin D by transglutaminase 2 through protein cross-linking promotes cell survival
Q53140520Divergent results induced by different types of septic shock in transglutaminase 2 knockout mice.
Q35144563Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice
Q51653169Inter-molecular crosslinking activity is engendered by the dimeric form of transglutaminase 2.
Q35176934Novel 3-arylethynyl-substituted thieno[3,4-b]pyrazine derivatives as human transglutaminase 2 inhibitors.
Q47676785Pluripotency and a secretion mechanism of Drosophila Transglutaminase
Q28247511Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional protein
Q59794754Renal Cell Carcinoma Is Abrogated by p53 Stabilization through Transglutaminase 2 Inhibition
Q92276539Search for Novel Diagnostic Biomarkers of Prostate Inflammation-Related Disorders: Role of Transglutaminase Isoforms as Potential Candidates
Q33490653The mechanism of transglutaminase 2 inhibition with glucosamine: implications of a possible anti-inflammatory effect through transglutaminase inhibition
Q36855739Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.
Q64899070Transglutaminase 2 Up-Regulation Is Associated with Inflammatory Response in PBMC from Healthy Subjects with Hypovitaminosis D.
Q38065965Transglutaminase 2 and NF-κB: an odd couple that shapes breast cancer phenotype
Q39798025Transglutaminase 2 as a cisplatin resistance marker in non-small cell lung cancer
Q53288102Transglutaminase 2 gene ablation protects against renal ischemic injury by blocking constant NF-κB activation
Q28069852Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death
Q39017211Transglutaminase 2 inhibitor abrogates renal cell carcinoma in xenograft models
Q39786229Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells
Q38713951Transglutaminase-catalyzed incorporation of polyamines masks the DNA-binding region of the transcription factor Relish
Q43954716Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-κB-like transcription factor relish
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