scholarly article | Q13442814 |
P2093 | author name string | Hong Tang | |
Xia Wang | |||
Yong Lin | |||
Zi Li | |||
Lang Bai | |||
Wenshu Chen | |||
Shanling Xu | |||
P2860 | cites work | The Hallmarks of Cancer | Q221226 |
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis | Q24300707 | ||
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis | Q24300734 | ||
TNF-alpha induces two distinct caspase-8 activation pathways | Q24313656 | ||
Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis | Q24609324 | ||
Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation | Q28140363 | ||
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination | Q28284721 | ||
Shared principles in NF-kappaB signaling | Q29547234 | ||
Nuclear factor-kappaB in cancer development and progression | Q29547879 | ||
NF-kappaB: linking inflammation and immunity to cancer development and progression | Q29614597 | ||
Acquired activation of the Akt/cyclooxygenase-2/Mcl-1 pathway renders lung cancer cells resistant to apoptosis | Q33714703 | ||
Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression | Q33978041 | ||
DNA damage-induced apoptosis | Q34312499 | ||
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins | Q34377284 | ||
The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy | Q34596902 | ||
TRAF2 exerts its antiapoptotic effect by regulating the expression of Krüppel-like factor LKLF | Q35169970 | ||
Nuclear factor-kappaB: the enemy within | Q35893620 | ||
Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics - an update | Q36066038 | ||
Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs | Q36085634 | ||
The Akt/PKB pathway: molecular target for cancer drug discovery | Q36313193 | ||
Heat shock protein 90: the cancer chaperone | Q36834685 | ||
Akt-dependent and -independent mechanisms of mTOR regulation in cancer | Q37114404 | ||
Drug discovery approaches targeting the PI3K/Akt pathway in cancer | Q37270455 | ||
Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells | Q37273453 | ||
Targeting the PI3K/AKT pathway for the treatment of prostate cancer | Q37564760 | ||
Akt is a downstream target of NF-kappa B. | Q38288465 | ||
Concurrent blockade of the NF-kappaB and Akt pathways potently sensitizes cancer cells to chemotherapeutic-induced cytotoxicity | Q39731546 | ||
Attenuating Smac mimetic compound 3-induced NF-kappaB activation by luteolin leads to synergistic cytotoxicity in cancer cells | Q39801796 | ||
IKKbeta-mediated nuclear factor-kappaB activation attenuates smac mimetic-induced apoptosis in cancer cells | Q39840485 | ||
Blockage of NF-kappaB by IKKbeta- or RelA-siRNA rather than the NF-kappaB super-suppressor IkappaBalpha mutant potentiates adriamycin-induced cytotoxicity in lung cancer cells | Q39959876 | ||
Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells | Q40123984 | ||
Sensitization of TNF-induced cytotoxicity in lung cancer cells by concurrent suppression of the NF-kappaB and Akt pathways | Q40168027 | ||
A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells | Q40171730 | ||
The essential role of the death domain kinase receptor-interacting protein in insulin growth factor-I-induced c-Jun N-terminal kinase activation | Q40263696 | ||
Phase I pharmacokinetic-pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers | Q40425901 | ||
17-allylamino-17-demethoxygeldanamycin synergistically potentiates tumor necrosis factor-induced lung cancer cell death by blocking the nuclear factor-kappaB pathway | Q46902088 | ||
Association of constitutive nuclear factor-kappaB activation with aggressive aspects and poor prognosis in cervical cancer. | Q53303723 | ||
Potential biomarkers involving IKK/RelA signal in early stage non-small cell lung cancer | Q80539024 | ||
P433 | issue | 1 | |
P921 | main subject | NF-κB | Q411114 |
P304 | page(s) | 45-54 | |
P577 | publication date | 2011-01-01 | |
P1433 | published in | Apoptosis | Q15749546 |
P1476 | title | Blocking NF-κB and Akt by Hsp90 inhibition sensitizes Smac mimetic compound 3-induced extrinsic apoptosis pathway and results in synergistic cancer cell death | |
P478 | volume | 16 |
Q35549167 | A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis |
Q33861908 | Abrus agglutinin suppresses human hepatocellular carcinoma in vitro and in vivo by inducing caspase-mediated cell death. |
Q41959409 | Geldanamycin-mediated inhibition of heat shock protein 90 partially activates dendritic cells, but interferes with their full maturation, accompanied by impaired upregulation of RelB. |
Q53123340 | HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells. |
Q43610455 | Heat effect induces production of inflammatory cytokines through heat shock protein 90 pathway in cornea cells. |
Q35517613 | Heat shock protein-90 inhibitors enhance antigen expression on melanomas and increase T cell recognition of tumor cells |
Q37615208 | Histone H4 expression is cooperatively maintained by IKKβ and Akt1 which attenuates cisplatin-induced apoptosis through the DNA-PK/RIP1/IAPs signaling cascade |
Q35823157 | Hsp90 inhibitors and drug resistance in cancer: the potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugs |
Q39552773 | Quantifying nuclear p65 as a parameter for NF-κB activation: Correlation between ImageStream cytometry, microscopy, and Western blot |
Q37151621 | RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species |
Q91522941 | RIP1 promotes proliferation through G2/M checkpoint progression and mediates cisplatin-induced apoptosis and necroptosis in human ovarian cancer cells |
Q38721721 | Revealing protein networks and gene-drug connectivity in cancer from direct information. |
Q37900640 | The role of inflammation in the pathogenesis of lung cancer |
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