| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1024905825 |
| P356 | DOI | 10.1038/NATURE06001 |
| P698 | PubMed publication ID | 17637676 |
| P5875 | ResearchGate publication ID | 6200236 |
| P50 | author | Douglas A. Lauffenburger | Q59755238 |
| Kevin A. Janes | Q66393200 | ||
| P2093 | author name string | Joan S Brugge | |
| Kathryn Miller-Jensen | |||
| P2860 | cites work | Tissue-specificity of apoptosis in hepatoma-derived cell lines | Q40534397 |
| Adenovirus vector-induced inflammation: capsid-dependent induction of the C-C chemokine RANTES requires NF-kappa B. | Q40658021 | ||
| Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway | Q40830298 | ||
| Cell type and stimulus specific regulation of chemokine gene expression | Q42802451 | ||
| Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis | Q45862074 | ||
| A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. | Q51307059 | ||
| A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis | Q73587546 | ||
| A compendium of signals and responses triggered by prodeath and prosurvival cytokines | Q80394534 | ||
| A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway | Q21735927 | ||
| Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes | Q24534395 | ||
| Antiviral actions of interferons | Q24550676 | ||
| Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells | Q24563114 | ||
| The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates | Q28282895 | ||
| Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures | Q29547700 | ||
| NF-kappaB: linking inflammation and immunity to cancer development and progression | Q29614597 | ||
| Data-driven modelling of signal-transduction networks | Q31068825 | ||
| Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data | Q33209549 | ||
| Signaling networks: the origins of cellular multitasking | Q33923713 | ||
| Tumor necrosis factor signaling. | Q34185821 | ||
| Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems | Q34292599 | ||
| The ins and outs of signalling | Q34311175 | ||
| Bow ties, metabolism and disease | Q34343513 | ||
| Single cell profiling of potentiated phospho-protein networks in cancer cells. | Q34549433 | ||
| Cancer gene therapy: fringe or cutting edge? | Q34572090 | ||
| Issues and progress with protein kinase inhibitors for cancer treatment | Q35096214 | ||
| Predicting therapeutic value in the lead optimization phase of drug discovery | Q35140840 | ||
| Targeting the PI3K-Akt pathway in human cancer: rationale and promise | Q35571372 | ||
| A biological approach to computational models of proteomic networks | Q36365865 | ||
| Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway | Q37647530 | ||
| The response of human epithelial cells to TNF involves an inducible autocrine cascade | Q40300089 | ||
| Functional interactions of antiapoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus. | Q40416354 | ||
| P433 | issue | 7153 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 604-608 | |
| P577 | publication date | 2007-07-18 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Common effector processing mediates cell-specific responses to stimuli | |
| P478 | volume | 448 |
| Q37721819 | A multipathway phosphoproteomic signaling network model of idiosyncratic drug- and inflammatory cytokine-induced toxicity in human hepatocytes |
| Q37205345 | A multivariate model of ErbB network composition predicts ovarian cancer cell response to canertinib |
| Q37028306 | A quantitative infection assay for human type I, II, and III interferon antiviral activities |
| Q30410515 | A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies |
| Q36895696 | ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling |
| Q30415276 | An ERK-p38 subnetwork coordinates host cell apoptosis and necrosis during coxsackievirus B3 infection |
| Q30252189 | An engineering design approach to systems biology |
| Q35082775 | An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha |
| Q30157382 | An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment. |
| Q34871428 | Antiviral-activated dendritic cells: a paracrine-induced response state |
| Q31162178 | Benchmarking substrate-based kinase activity inference using phosphoproteomic data |
| Q59804156 | CRB3 and the FERM protein EPB41L4B regulate proliferation of mammary epithelial cells through the release of amphiregulin |
| Q36327210 | Capturing cell-fate decisions from the molecular signatures of a receptor-dependent signaling response |
| Q39313461 | Cell type specificity of signaling: view from membrane receptors distribution and their downstream transduction networks |
| Q28267574 | Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells |
| Q27013063 | Cell-to-cell variability in cell death: can systems biology help us make sense of it all? |
| Q89748642 | Cell-type-specific signaling networks in heterocellular organoids |
| Q39887307 | Combined inhibition of MEK and mTOR signaling inhibits initiation and progression of colorectal cancer |
| Q35018212 | Computational modeling of mammalian signaling networks |
| Q47427679 | Computer simulations in connective tissue research: successes and challenges |
| Q34977987 | Contrast-Enhanced Nanofocus X-Ray Computed Tomography Allows Virtual Three-Dimensional Histopathology and Morphometric Analysis of Osteoarthritis in Small Animal Models. |
| Q36208942 | Cross-talk between receptor tyrosine kinase and tumor necrosis factor-α signaling networks regulates apoptosis but not proliferation |
| Q41771446 | Crosstalk and signaling switches in mitogen-activated protein kinase cascades |
| Q42423679 | Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation |
| Q37081858 | Cytokine-induced signaling networks prioritize dynamic range over signal strength |
| Q31156368 | Data-driven modeling of cellular stimulation, signaling and output response in RAW 264.7 cells |
| Q33766969 | Defining the antigen receptor-dependent regulatory network that induces arrest of cycling immature B-lymphocytes |
| Q30519163 | Dramatic reduction of dimensionality in large biochemical networks owing to strong pair correlations |
| Q33754562 | Dynamic, Large-Scale Profiling of Transcription Factor Activity from Live Cells in 3D Culture |
| Q39025655 | Experimental and computational tools for analysis of signaling networks in primary cells |
| Q38989129 | Foxp3 inhibits HDAC1 activity to modulate gene expression in human T cells |
| Q37236447 | From oncogene to network addiction: the new frontier of cancer genomics and therapeutics |
| Q43177116 | Functional characterization of eight human cytochrome P450 1A2 gene variants by recombinant protein expression. |
| Q41976129 | Gene network dynamics controlling keratinocyte migration |
| Q40789598 | Generalized selection to overcome innate immunity selects for host breadth in an RNA virus |
| Q34858312 | How cells explore shape space: a quantitative statistical perspective of cellular morphogenesis |
| Q30434682 | Identifying single-cell molecular programs by stochastic profiling |
| Q28551108 | Improving Osteoblast Response In Vitro by a Nanostructured Thin Film with Titanium Carbide and Titanium Oxides Clustered around Graphitic Carbon |
| Q34137584 | In silico models of cancer |
| Q63976669 | In situ 10-cell RNA sequencing in tissue and tumor biopsy samples |
| Q37657176 | In vivo systems analysis identifies spatial and temporal aspects of the modulation of TNF-α-induced apoptosis and proliferation by MAPKs |
| Q33540104 | Inferring cluster-based networks from differently stimulated multiple time-course gene expression data |
| Q39685676 | Interrogating cell signalling network sensitively monitors cell fate transition during early differentiation of mouse embryonic stem cells |
| Q30427503 | Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression |
| Q34391697 | Light-guiding hydrogels for cell-based sensing and optogenetic synthesis in vivo. |
| Q37101002 | Linear combinations of docking affinities explain quantitative differences in RTK signaling |
| Q92957659 | Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity |
| Q30417244 | Modeling the latent dimensions of multivariate signaling datasets |
| Q30413382 | Models of signalling networks - what cell biologists can gain from them and give to them |
| Q37977173 | Multi-pathway network analysis of mammalian epithelial cell responses in inflammatory environments |
| Q42374637 | Multipathway kinase signatures of multipotent stromal cells are predictive for osteogenic differentiation: tissue-specific stem cells |
| Q40001089 | Multipathway model enables prediction of kinase inhibitor cross-talk effects on migration of Her2-overexpressing mammary epithelial cells |
| Q27010700 | Multiscale models of cell signaling |
| Q37087536 | Network medicine |
| Q28390885 | Network-level effects of kinase inhibitors modulate TNF-α-induced apoptosis in the intestinal epithelium |
| Q27015094 | Normal morphogenesis of epithelial tissues and progression of epithelial tumors |
| Q42564735 | Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation. |
| Q42922990 | Paring down signaling complexity |
| Q36453271 | Patient specific proteolytic activity of monocyte-derived macrophages and osteoclasts predicted with temporal kinase activation states during differentiation. |
| Q39434337 | Phosphoproteomic studies of receptor tyrosine kinases: future perspectives |
| Q47200001 | Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling. |
| Q34616800 | Predicting cytotoxic T-cell age from multivariate analysis of static and dynamic biomarkers |
| Q39449548 | Projection to latent pathways (PLP): a constrained projection to latent variables (PLS) method for elementary flux modes discrimination. |
| Q33747611 | Protein conservation and variation suggest mechanisms of cell type-specific modulation of signaling pathways |
| Q33651942 | Quantitative analysis of castration resistant prostate cancer progression through phosphoproteome signaling |
| Q37330722 | Quantitative modeling perspectives on the ErbB system of cell regulatory processes |
| Q36936477 | Quantitative phosphoproteomic analysis of signaling network dynamics. |
| Q34081008 | RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects |
| Q37608729 | Recent advances and new opportunities in lung mechanobiology |
| Q33871842 | Receptor tyrosine kinase coactivation networks in cancer |
| Q58802584 | Reconstructing phosphorylation signalling networks from quantitative phosphoproteomic data |
| Q92228845 | Robust latent-variable interpretation of in vivo regression models by nested resampling |
| Q33691766 | Screening the cellular microenvironment: a role for microfluidics |
| Q41949853 | Short-term information processing, long-term responses: Insights by mathematical modeling of signal transduction. Early activation dynamics of key signaling mediators can be predictive for cell fate decisions |
| Q34530613 | Signaling network prediction by the Ontology Fingerprint enhanced Bayesian network |
| Q30411399 | Simultaneous profiling of 194 distinct receptor transcripts in human cells |
| Q24646228 | Small RNAs establish delays and temporal thresholds in gene expression |
| Q30415094 | Stochastic profiling of transcriptional regulatory heterogeneities in tissues, tumors and cultured cells |
| Q33915637 | Systematic quantitative characterization of cellular responses induced by multiple signals |
| Q34111154 | Systems pharmacology of arrhythmias |
| Q30276641 | TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors |
| Q37945786 | Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches |
| Q34613012 | Temporal decoding of MAP kinase and CREB phosphorylation by selective immediate early gene expression |
| Q35878760 | The DIONESUS algorithm provides scalable and accurate reconstruction of dynamic phosphoproteomic networks to reveal new drug targets |
| Q39152114 | The Heterocellular Emergence of Colorectal Cancer |
| Q34785870 | The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis. |
| Q30417181 | The extraction of simple relationships in growth factor-specific multiple-input and multiple-output systems in cell-fate decisions by backward elimination PLS regression |
| Q39813810 | Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death |
| Q28477321 | Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli |
| Q47804852 | Transcriptome analysis of reproductive-stage Arabidopsis plants exposed gamma-ray irradiation at various doses |
| Q45073569 | Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer |
| Q38060916 | Understanding resistance to combination chemotherapy |
| Q39355451 | Using network biology to bridge pharmacokinetics and pharmacodynamics in oncology |
| Q30617646 | Using partial least squares regression to analyze cellular response data |
Search more.