Sumoylation is tumor-suppressive and confers proliferative quiescence to hematopoietic progenitors in Drosophila melanogaster larvae

scientific article

Sumoylation is tumor-suppressive and confers proliferative quiescence to hematopoietic progenitors in Drosophila melanogaster larvae is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/BIO.2011043
P932PMC publication ID3507282
P698PubMed publication ID23213407

P2093author name stringChristina Nadar
Indira Paddibhatla
Marta E Kalamarz
Shubha Govind
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Transcription of the Drosophila CKI gene dacapo is regulated by a modular array of cis-regulatory sequences.Q52123721
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Uncoupling cell fate determination from patterned cell division in the Drosophila eye.Q52535869
The tumor suppressor gene, lethal(2)giant larvae (1(2)g1), is required for cell shape change of epithelial cells during Drosophila development.Q52548490
A role for the Drosophila Toll/Cactus pathway in larval hematopoiesis.Q52562914
The two origins of hemocytes in Drosophila.Q52610345
Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre.Q52677781
Definition of Drosophila hemocyte subsets by cell-type specific antigens.Q52688928
New hemocyte-specific enhancer-reporter transgenes for the analysis of hematopoiesis in Drosophila.Q52699478
Tumor susceptibility of p21(Waf1/Cip1)-deficient mice.Q53396439
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Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer modelQ73263614
Hematopoietic stem cell quiescence maintained by p21cip1/waf1Q73532192
Expression analysis of Ubc9, the single small ubiquitin-like modifier (SUMO) E2 conjugating enzyme, in normal and malignant tissuesQ84439039
A Drosophila protein-interaction map centered on cell-cycle regulatorsQ24791344
Cellular immune response to parasitization in Drosophila requires the EBF orthologue collierQ24798651
Role for sumoylation in systemic inflammation and immune homeostasis in Drosophila larvaeQ27312487
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Targeted gene expression as a means of altering cell fates and generating dominant phenotypesQ27861039
Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogasterQ28265495
NF-kappaB: linking inflammation and immunity to cancer development and progressionQ29614597
Stem cells and niches: mechanisms that promote stem cell maintenance throughout lifeQ29620450
A directed screen for genes involved in Drosophila blood cell activationQ30833737
Postembryonic hematopoiesis in DrosophilaQ31847453
Hematopoietic stem cells in DrosophilaQ33552364
Drosophila in cancer research. An expanding role.Q33818861
Innate immunity in Drosophila: Pathogens and pathwaysQ33856116
A protein trap strategy to detect GFP-tagged proteins expressed from their endogenous loci in Drosophila.Q33952883
Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse modelsQ34162785
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient miceQ34381923
Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?Q34542144
Mutations in the NF-kappaB signaling pathway: implications for human diseaseQ34577553
An overexpression screen in Drosophila for genes that restrict growth or cell-cycle progression in the developing eyeQ34615955
Analysis of Ras-induced overproliferation in Drosophila hemocytes.Q34616733
The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein familyQ35079217
Drosophila models for cancer research.Q36344450
SUMO and NF-kappaB ties.Q36832369
Functional analysis of the SUMOylation pathway in Drosophila.Q37269497
Good cells gone bad: the cellular origins of cancer.Q37690993
Intestinal stem cells and epithelial-mesenchymal interactions in the crypt and stem cell nicheQ37783807
Quiescent, Slow-Cycling Stem Cell Populations in Cancer: A Review of the Evidence and Discussion of SignificanceQ37799253
The PDGF/VEGF receptor controls blood cell survival in DrosophilaQ40538412
Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.Q40807096
A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors.Q42878689
Cellular immune response to parasite infection in the Drosophila lymph gland is developmentally regulatedQ43485379
The Drosophila lymph gland as a developmental model of hematopoiesisQ46163386
Lamellocyte differentiation in Drosophila larvae parasitized by LeptopilinaQ46307854
P275copyright licenseCreative Commons Attribution-NonCommercial-ShareAlike 3.0 UnportedQ15643954
P6216copyright statuscopyrightedQ50423863
P433issue3
P921main subjectDrosophila melanogasterQ130888
protein sumoylationQ3503705
P304page(s)161-172
P577publication date2011-12-28
P1433published inBiology OpenQ27724268
P1476titleSumoylation is tumor-suppressive and confers proliferative quiescence to hematopoietic progenitors in Drosophila melanogaster larvae
P478volume1

Reverse relations

cites work (P2860)
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