Regulatory T cells and innate immune regulation in tumor immunity

scientific article published on 13 July 2006

Regulatory T cells and innate immune regulation in tumor immunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S00281-006-0022-7
P698PubMed publication ID16838179
P5875ResearchGate publication ID6947790

P2093author name stringRong-Fu Wang
P2860cites workRecognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptorsQ80444910
Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cellsQ81111394
Inducing and expanding regulatory T cell populations by foreign antigenQ81392563
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848Q24298297
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8Q24310398
Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell functionQ24317859
Cancer immunotherapy: moving beyond current vaccinesQ24548229
Recognition of single-stranded RNA viruses by Toll-like receptor 7Q24568101
Toll-like receptor signallingQ24570126
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cellsQ24645614
Inflammation and cancerQ24649640
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytesQ24676216
Human tumor antigens recognized by T lymphocytesQ24678508
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Foxp3 programs the development and function of CD4+CD25+ regulatory T cellsQ27860714
Pathogen recognition and innate immunityQ27861084
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathwayQ28216760
Toll-like receptors in innate immunityQ28297257
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptorsQ28303818
Regulatory T cell lineage specification by the forkhead transcription factor foxp3Q28510328
IRF-7 is the master regulator of type-I interferon-dependent immune responsesQ28511410
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNAQ28513215
Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and MetastasisQ29396371
Toll-like receptor control of the adaptive immune responsesQ29547305
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survivalQ29547865
Tumour-educated macrophages promote tumour progression and metastasisQ29614307
NF-kappaB: linking inflammation and immunity to cancer development and progressionQ29614597
NF-kappaB functions as a tumour promoter in inflammation-associated cancerQ29614598
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancerQ29614599
The immunobiology of cancer immunosurveillance and immunoeditingQ29616246
An essential role for Scurfin in CD4+CD25+ T regulatory cellsQ29618395
Tolerogenic dendritic cellsQ29618755
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responsesQ29619908
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancerQ29620068
Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph nodeQ30438088
Human tumor antigens for cancer vaccine developmentQ33776127
TLR7: A new sensor of viral infectionQ33780838
Regulatory T cells in autoimmmunity*.Q33904108
The specific regulation of immune responses by CD8+ T cells restricted by the MHC class Ib molecule, Qa-1.Q33932690
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporterQ33936032
The role of different subsets of T regulatory cells in controlling autoimmunityQ34096248
Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cellsQ34147162
Immunity against cancer: lessons learned from melanoma.Q34167925
Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancerQ34210036
Toll-like receptor 2 controls expansion and function of regulatory T cellsQ34264024
Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cellsQ34397184
Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation toleranceQ34448410
Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunityQ34505678
Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.Q34515741
Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.Q34529123
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunityQ34529549
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharideQ34531452
In vivo instruction of suppressor commitment in naive T cellsQ34548023
T-cell-mediated suppression of anti-tumor immunity. An explanation for progressive growth of an immunogenic tumorQ34709824
CD4+ CD25+ suppressor T cells: more questions than answersQ34716304
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitisQ34719541
Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanomaQ34943798
Enhancing antitumor immune responses: intracellular peptide delivery and identification of MHC class II-restricted tumor antigensQ35005930
Regulatory T cells under scrutinyQ35092531
Regulatory T cells in transplantation toleranceQ35092535
At the crossroads of inflammation and cancerQ35888450
An integrated view of suppressor T cell subsets in immunoregulationQ35936478
Qa-1 restriction of CD8+ suppressor T cellsQ35936489
Mechanisms and functional significance of tumour-induced dendritic-cell defectsQ35968465
CD4+ CD25+ T cells responding to serologically defined autoantigens suppress antitumor immune responsesQ35978636
License to heal: bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC.Q36119296
Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigensQ36228356
Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cellsQ36346300
Clonal analysis of cytotoxic and regulatory T cell responses against human melanomaQ36356458
Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligationQ36370469
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responsesQ36376333
The role of stroma in immune recognition and destruction of well-established solid tumorsQ36387256
Regulatory T cells and Toll-like receptors in tumor immunityQ36392367
Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cellsQ36402710
Innate immunity gone awry: linking microbial infections to chronic inflammation and cancerQ36404654
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon inductionQ40437839
Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cellsQ40498116
Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regressionQ40513415
Autologous melanoma-induced activation of regulatory T cells that suppress cytotoxic responseQ41720666
Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].Q41907086
Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cellsQ41908906
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cellsQ42944333
Analysis of regulatory CD8 T cells in Qa-1-deficient miceQ44903222
Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapyQ45871925
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesisQ46576855
Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the CAncer Prostate in Sweden StudyQ47755175
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cellsQ47991722
Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cellsQ50095546
Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivoQ56904016
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinomaQ56904280
Human CD4+ T Cells Express TLR5 and Its Ligand Flagellin Enhances the Suppressive Capacity and Expression of FOXP3 in CD4+CD25+ T Regulatory CellsQ57447880
Sequence Variants in Toll-Like Receptor Gene Cluster (TLR6-TLR1-TLR10) and Prostate Cancer RiskQ61853345
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptideQ73688337
Origin of regulatory T cells with known specificity for antigenQ74381747
Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cellsQ77291206
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cellsQ78806915
Cutting edge: self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cellsQ79317453
Reviving suppression?Q79841487
P433issue1
P304page(s)17-23
P577publication date2006-07-13
P1433published inSeminars in ImmunopathologyQ15724576
P1476titleRegulatory T cells and innate immune regulation in tumor immunity
P478volume28

Reverse relations

cites work (P2860)
Q48201872A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer
Q36821572Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?
Q37437275Blockade of MCP-1/CCR4 signaling-induced recruitment of activated regulatory cells evokes an antitumor immune response in head and neck squamous cell carcinoma
Q50960953Cancerous HLA class I expression and regulatory T cell infiltration in gastric cancer.
Q87033216Changes of Th17/Tc17 and Th17/Treg cells in endometrial carcinoma
Q39100186Circulating T regulatory cells migration and phenotype in glioblastoma patients: an in vitro study
Q35570420Distribution, characterization, and induction of CD8+ regulatory T cells and IL-17-producing CD8+ T cells in nasopharyngeal carcinoma.
Q50318735Effects of iodine-131 radiotherapy on Th17/Tc17 and Treg/Th17 cells of patients with differentiated thyroid carcinoma
Q64071947Gastric Cancer Stem Cells Effect on Th17/Treg Balance; A Bench to Beside Perspective
Q36049894Hepatocellular carcinoma and macrophage interaction induced tumor immunosuppression via Treg requires TLR4 signaling
Q55516289High levels of CCL2 or CCL4 in the tumor microenvironment predict unfavorable survival in lung adenocarcinoma.
Q34616226Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function
Q37413874IFN-alpha enhances peptide vaccine-induced CD8+ T cell numbers, effector function, and antitumor activity
Q92619203Imbalance of Th1/Th2 and Th17/Treg during the development of uterine cervical cancer
Q44798815Immune response in cervical lymph nodes from patients with primary oral squamous cell carcinoma
Q34265357Immunity over inability: The spontaneous regression of cancer
Q39628849In vitro selective depletion of CD4(+)CD25(+) regulatory T-cells from PBMC using anti-tac-SAP.
Q35895255Increased P-35, EBI3 Transcripts and Other Treg Markers in Peripheral Blood Mononuclear Cells of Breast Cancer Patients with Different clinical Stages
Q41066538Low intratumoral regulatory T cells and high peritumoral CD8(+) T cells relate to long-term survival in patients with pancreatic ductal adenocarcinoma after pancreatectomy
Q34847859Mesothelin virus-like particle immunization controls pancreatic cancer growth through CD8+ T cell induction and reduction in the frequency of CD4+ foxp3+ ICOS- regulatory T cells.
Q50042197New Insights into the Tumor Microenvironment Utilizing Protein Array Technology
Q42554303Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors.
Q35218562Resiquimod as an immunologic adjuvant for NY-ESO-1 protein vaccination in patients with high-risk melanoma
Q42323672T regulatory cell markers in oral squamous cell carcinoma: Relationship with survival and tumor aggressiveness.
Q61812765The Oncogene Addiction Switch from NOTCH to PI3K Requires Simultaneous Targeting of NOTCH and PI3K Pathway Inhibition in Glioblastoma
Q33631986The role of regulatory T cells in cancer
Q35798986Trial watch: Naked and vectored DNA-based anticancer vaccines
Q64099099Zoledronic acid blocks the interaction between breast cancer cells and regulatory T-cells
Q49481424hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway

Search more.