Enhanced suppressive capacity of tumor-infiltrating myeloid-derived suppressor cells compared with their peripheral counterparts

scientific article published on 23 September 2013

Enhanced suppressive capacity of tumor-infiltrating myeloid-derived suppressor cells compared with their peripheral counterparts is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/IJC.28449
P698PubMed publication ID23983191
P5875ResearchGate publication ID256189890

P2093author name stringKris Thielemans
Joeri L Aerts
Sandra Van Lint
Sarah K Maenhout
Perpetua U Emeagi
P2860cites workProinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cellsQ24658240
Myeloid-derived suppressor cells as regulators of the immune systemQ28131637
Cancer despite immunosurveillance: immunoselection and immunosubversionQ28263865
Subsets of myeloid-derived suppressor cells in tumor-bearing miceQ29614297
IDO expression by dendritic cells: tolerance and tryptophan catabolismQ29614752
Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteineQ33584867
Antigen-specific CD4(+) T cells regulate function of myeloid-derived suppressor cells in cancer via retrograde MHC class II signalingQ33772651
Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cellsQ33873201
Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cellsQ33919954
HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironmentQ34243443
Tumor-associated CD8+ T cell tolerance induced by bone marrow-derived immature myeloid cellsQ34312635
Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cellsQ34597798
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responsesQ34650346
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cellsQ35052425
Does the immune system see tumors as foreign or self?Q35077428
The balance of immune responses: costimulation verse coinhibitionQ35998858
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapyQ36108095
Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppressionQ36259867
Myeloid derived suppressor cells in human diseasesQ36338349
The B7 family and cancer therapy: costimulation and coinhibitionQ36944386
Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunityQ36996588
The complex role of B7 molecules in tumor immunologyQ37304913
Myeloid-derived suppressor cell heterogeneity and subset definition.Q37695457
Subsets, expansion and activation of myeloid-derived suppressor cellsQ37727050
Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 familyQ37864700
Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patientsQ37961577
T-regulatory cells: key players in tumor immune escape and angiogenesisQ38006901
On the armament and appearances of human myeloid-derived suppressor cellsQ38031742
Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth.Q39244686
Regulatory T cells stimulate B7-H1 expression in myeloid-derived suppressor cells in ret melanomasQ39424337
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activityQ40013431
CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cellsQ40259796
Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasisQ40339595
Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes.Q40836916
The terminology issue for myeloid-derived suppressor cellsQ42425163
In vivo suppressive function of myeloid-derived suppressor cells is limited to the inflammatory siteQ42728755
Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cellsQ43582877
Studying the immunosuppressive role of indoleamine 2,3-dioxygenase: tryptophan metabolites suppress rat allogeneic T-cell responses in vitro and in vivoQ45197119
CD86 and CD80 differentially modulate the suppressive function of human regulatory T cellsQ47192084
Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma.Q55056515
Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing HostQ57054792
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)1077-1090
P577publication date2013-09-23
P1433published inInternational Journal of CancerQ332492
P1476titleEnhanced suppressive capacity of tumor-infiltrating myeloid-derived suppressor cells compared with their peripheral counterparts
P478volume134

Reverse relations

cites work (P2860)
Q36413721A core of kinase-regulated interactomes defines the neoplastic MDSC lineage
Q34365909A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice
Q34334399AZD1480 delays tumor growth in a melanoma model while enhancing the suppressive activity of myeloid-derived suppressor cells.
Q42124738Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy
Q35798966Axitinib increases the infiltration of immune cells and reduces the suppressive capacity of monocytic MDSCs in an intracranial mouse melanoma model.
Q26750382Cancer-Associated Myeloid Regulatory Cells
Q40903579Change in CD3ζ-chain expression is an independent predictor of disease status in head and neck cancer patients
Q37447879Combined VEGFR and CTLA-4 blockade increases the antigen-presenting function of intratumoral DCs and reduces the suppressive capacity of intratumoral MDSCs
Q57817490Diamonds in the Rough: Harnessing Tumor-Associated Myeloid Cells for Cancer Therapy
Q38993068Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy.
Q38592376Drafting the proteome landscape of myeloid-derived suppressor cells.
Q37107253Dynamics of the spleen and its significance in a murine H22 orthotopic hepatoma model.
Q35828574Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer
Q58542370Gemcitabine nanoparticles promote antitumor immunity against melanoma
Q36597506Interleukin 33 in tumor microenvironment is crucial for the accumulation and function of myeloid-derived suppressor cells
Q36638606Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally located tumours
Q34654430Intratumoral administration of mRNA encoding a fusokine consisting of IFN-β and the ectodomain of the TGF-β receptor II potentiates antitumor immunity
Q42840029Location, location, location: functional and phenotypic heterogeneity between tumor-infiltrating and non-infiltrating myeloid-derived suppressor cells
Q92794706Mediators of Inflammation-Driven Expansion, Trafficking, and Function of Tumor-Infiltrating MDSCs
Q89976160Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer
Q98465646Myeloid-Derived Suppressor Cells in Tumors: From Mechanisms to Antigen Specificity and Microenvironmental Regulation
Q89613164Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
Q37732211Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection
Q92853591Perforin and Granzyme B Expressed by Murine Myeloid-Derived Suppressor Cells: A Study on Their Role in Outgrowth of Cancer Cells
Q28080262Signal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapy
Q41968526TLR7-based cancer immunotherapy decreases intratumoral myeloid-derived suppressor cells and blocks their immunosuppressive function
Q28388630The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
Q33660069The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.
Q38239562The roles of myeloid-derived suppressor cells in transplantation
Q59799202Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression
Q58780996Turn Back the TIMe: Targeting Tumor Infiltrating Myeloid Cells to Revert Cancer Progression

Search more.