The novel α-glucan YCP improves the survival rates and symptoms in septic mice by regulating myeloid-derived suppressor cells.

scientific article published on 26 June 2017

The novel α-glucan YCP improves the survival rates and symptoms in septic mice by regulating myeloid-derived suppressor cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/APS.2017.27
P932PMC publication ID5589966
P698PubMed publication ID28649127

P2093author name stringDan Liu
Xiang-Dong Gao
Xiu-Jun Li
Ming You
Huan Dou
Wen-Bing Yao
Ya-Yi Hou
Guang-Feng Zhao
Yu-Xian Song
P2860cites workMyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsisQ36229458
Yeast-Derived Particulate β-Glucan Treatment Subverts the Suppression of Myeloid-Derived Suppressor Cells (MDSC) by Inducing Polymorphonuclear MDSC Apoptosis and Monocytic MDSC Differentiation to APC in Cancer.Q36600997
Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axisQ37200858
Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approachQ37233354
Immunodesign of experimental sepsis by cecal ligation and punctureQ37368111
Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and functionQ37808561
Myeloid-derived suppressor cells in the inflammatory bowel diseasesQ38118052
Human Myeloid-derived Suppressor Cells are Associated With Chronic Immune Suppression After Severe Sepsis/Septic ShockQ39779016
Protective effect of beta-glucan on lung injury after cecal ligation and puncture in rats.Q40432076
Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.Q40605195
Immature myeloid Gr-1+ CD11b+ cells from lipopolysaccharide-immunosuppressed mice acquire inhibitory activity in the bone marrow and migrate to lymph nodes to exert their suppressive functionQ40904585
Lung-residing myeloid-derived suppressors display dual functionality in murine pulmonary tuberculosisQ41718876
A high frequency of MDSCs in sepsis patients, with the granulocytic subtype dominating in gram-positive casesQ42210487
Editorial: the contribution of myeloid-derived suppression to inflammatory diseaseQ42361557
Immunological response to (1,4)-alpha-D-glucan in the lung and spleen of endotoxin-stimulated juvenile rats.Q44765955
β-Glucan enhances antitumor immune responses by regulating differentiation and function of monocytic myeloid-derived suppressor cells.Q45801273
Purification, characterization and enzymatic degradation of YCP, a polysaccharide from marine filamentous fungus Phoma herbarum YS4108.Q46483851
Elimination of Granulocytic Myeloid-Derived Suppressor Cells in Lupus-Prone Mice Linked to Reactive Oxygen Species-Dependent Extracellular Trap FormationQ46662797
Progesterone enhances immunoregulatory activity of human mesenchymal stem cells via PGE2 and IL-6.Q46757921
CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic stressQ46925832
Myeloid-derived suppressor cells control microbial sepsisQ48165805
Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor.Q54421148
Oral and systemic administration of beta-glucan protects against lipopolysaccharide-induced shock and organ injury in ratsQ79913084
Pharmacokinetics of fungal (1-3)-beta-D-glucans following intravenous administration in ratsQ80335566
"Merinoff symposium 2010: sepsis"-speaking with one voiceQ24595002
Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 proteinQ24641894
Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cellsQ24658240
Myeloid derived suppressor cells-An overview of combat strategies to increase immunotherapy efficacyQ28082461
Myeloid-derived suppressor cells as regulators of the immune systemQ28131637
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shockQ28244377
S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end productsQ28276090
The epidemiology of sepsis in the United States from 1979 through 2000Q29547760
The pathophysiology and treatment of sepsisQ29619103
Protective effect of beta-glucan against oxidative organ injury in a rat model of sepsisQ33217018
Macrophage receptors of polysaccharide isolated from a marine filamentous fungus Phoma herbarum YS4108.Q33477866
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapyQ33828888
Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function.Q33979918
Normal responses to injury prevent systemic inflammation and can be immunosuppressiveQ34141225
MicroRNA 21 (miR-21) and miR-181b couple with NFI-A to generate myeloid-derived suppressor cells and promote immunosuppression in late sepsisQ34298403
Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathwayQ34314210
The effect of age on the development and outcome of adult sepsisQ34479183
Marked elevation of human circulating CD4+CD25+ regulatory T cells in sepsis-induced immunoparalysis.Q34535214
Oral delivery and gastrointestinal absorption of soluble glucans stimulate increased resistance to infectious challengeQ34558787
Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremonyQ34585151
Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patientsQ34599210
Sepsis definitions: time for changeQ34649118
Toll-like receptor 2 and Toll-like receptor 4-dependent activation of B cells by a polysaccharide from marine fungus Phoma herbarum YS4108Q34654099
A paradoxical role for myeloid-derived suppressor cells in sepsis and traumaQ34699543
Immunomodulatory effects of polysaccharide from marine fungus Phoma herbarum YS4108 on T cells and dendritic cells.Q34707229
Preparation and immunomodulating activities of a library of low-molecular-weight α-glucans.Q35209043
Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progressionQ35478848
Fungal β-Glucans and Mammalian ImmunityQ35538040
A genomic storm in critically injured humansQ35627656
Immunosuppression in patients who die of sepsis and multiple organ failureQ35991015
Myeloid-derived suppressor cells evolve during sepsis and can enhance or attenuate the systemic inflammatory responseQ36018144
Particulate β-glucan regulates the immunosuppression of granulocytic myeloid-derived suppressor cells by inhibiting NFIA expressionQ36060257
P433issue9
P304page(s)1269-1281
P577publication date2017-06-26
P1433published inActa Pharmacologica SinicaQ15749885
P1476titleThe novel α-glucan YCP improves the survival rates and symptoms in septic mice by regulating myeloid-derived suppressor cells.
P478volume38

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Q92132610Development of a Bioinformatics Framework for Identification and Validation of Genomic Biomarkers and Key Immunopathology Processes and Controllers in Infectious and Non-infectious Severe Inflammatory Response Syndromecites workP2860

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