NMDA receptor subunit-dependent [Ca2+] signaling in individual hippocampal dendritic spines

scientific journal article

NMDA receptor subunit-dependent [Ca2+] signaling in individual hippocampal dendritic spines is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1523/JNEUROSCI.1221-05.2005
P3181OpenCitations bibliographic resource ID1954432
P932PMC publication ID6725044
P698PubMed publication ID15987933

P50authorVolker ScheussQ56517298
P2093author name stringKarel Svoboda
Aleksander Sobczyk
P2860cites workGenetic enhancement of learning and memory in miceQ22010371
Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockadeQ24561819
ScanImage: flexible software for operating laser scanning microscopesQ24801746
Synaptic calcium transients in single spines indicate that NMDA receptors are not saturatedQ48204756
Plasticity of calcium channels in dendritic spinesQ48218606
Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivoQ48235995
Fractional contribution of calcium to the cation current through glutamate receptor channelsQ48264301
Variability of neurotransmitter concentration and nonsaturation of postsynaptic AMPA receptors at synapses in hippocampal cultures and slicesQ48268895
Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus.Q48377872
Dendritic spines as individual neuronal compartments for synaptic Ca2+ responsesQ48625348
Ca2+ signaling requirements for long-term depression in the hippocampus.Q49047357
Fractional Ca2+ currents through somatic and dendritic glutamate receptor channels of rat hippocampal CA1 pyramidal neurones.Q49056533
Direct measurement of coupling between dendritic spines and shafts.Q51649619
LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite.Q52030569
Mechanisms of calcium decay kinetics in hippocampal spines: role of spine calcium pumps and calcium diffusion through the spine neck in biochemical compartmentalization.Q52081862
The location and function of NMDA receptors in cat and kitten visual cortexQ69371644
Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristicsQ69702481
Regulation of spine calcium dynamics by rapid spine motilityQ73168260
Somatic EPSP amplitude is independent of synapse location in hippocampal pyramidal neuronsQ74246527
Diversity and dynamics of dendritic signalingQ28142303
Two forms of synaptic plasticity with distinct dependence on age, experience, and NMDA receptor subtype in rat visual cortexQ28189244
Changing subunit composition of heteromeric NMDA receptors during development of rat cortexQ28251123
Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neuronsQ28363018
Developmental and regional expression in the rat brain and functional properties of four NMDA receptorsQ28570615
Molecular diversity of the NMDA receptor channelQ28585736
Structural basis of long-term potentiation in single dendritic spinesQ29547598
Dendritic spine changes associated with hippocampal long-term synaptic plasticityQ29614373
Structure and function of dendritic spinesQ29617057
Transient and persistent dendritic spines in the neocortex in vivoQ29618402
Long-term potentiation--a decade of progress?Q29619421
Rapid Dendritic Morphogenesis in CA1 Hippocampal Dendrites Induced by Synaptic ActivityQ29997835
Two-photon imaging in living brain slicesQ30707400
Brominated 7-hydroxycoumarin-4-ylmethyls: photolabile protecting groups with biologically useful cross-sections for two photon photolysisQ31904757
NMDAR EPSC kinetics do not regulate the critical period for LTP at thalamocortical synapsesQ32063788
Imaging calcium concentration dynamics in small neuronal compartments.Q33197918
Interplay between sodium and calcium dynamics in granule cell presynaptic terminalsQ33907761
Ligand-gated ion channel interactions with cytoskeletal and signaling proteinsQ33938793
NMDA receptor subunits: diversity, development and diseaseQ33950711
Ca(2+) signaling in dendritic spinesQ34278072
Evidence for silent synapses: implications for the expression of LTP.Q34303011
Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal sliceQ34311517
Dendritic spines as basic functional units of neuronal integrationQ34313960
NMDA channel regulation by channel-associated protein tyrosine kinase Src.Q34414146
NMDA receptor antagonists as analgesics: focus on the NR2B subtypeQ34455114
Opposing roles of synaptic and extrasynaptic NMDA receptors in neuronal calcium signalling and BDNF gene regulationQ35172825
NR2B-containing receptors mediate cross talk among hippocampal synapsesQ36047653
Calcium gradients and buffers in bovine chromaffin cellsQ39227699
Release and sequestration of calcium by ryanodine-sensitive stores in rat hippocampal neuronesQ39449873
Interaction with the NMDA receptor locks CaMKII in an active conformationQ40791785
A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion fluxQ40803792
NMDA receptor content of synapses in stratum radiatum of the hippocampal CA1 area.Q40891988
The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitroQ40955590
Simultaneous measurement of Ca2+ influx and reversal potentials in recombinant N-methyl-D-aspartate receptor channelsQ41200055
Blockade of "NMDA" receptors disrupts experience-dependent plasticity of kitten striate cortexQ41250860
The life cycle of Ca(2+) ions in dendritic spines.Q43879113
Activity-dependent decrease in NMDA receptor responses during development of the visual cortexQ44159410
The number of glutamate receptors opened by synaptic stimulation in single hippocampal spines.Q44777547
Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticityQ44895962
State-dependent calcium signaling in dendritic spines of striatal medium spiny neuronsQ45123834
Different modes of expression of AMPA and NMDA receptors in hippocampal synapsesQ48160411
P433issue26
P407language of work or nameEnglishQ1860
P921main subjectdendritic spineQ902079
P304page(s)6037-6046
P577publication date2005-06-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleNMDA receptor subunit-dependent [Ca2+] signaling in individual hippocampal dendritic spines
P478volume25

Reverse relations

cites work (P2860)
Q341176384-Carboxymethoxy-5,7-dinitroindolinyl-Glu: an improved caged glutamate for expeditious ultraviolet and two-photon photolysis in brain slices.
Q38080709A chemist and biologist talk to each other about caged neurotransmitters
Q59790674A machine learning approach for online automated optimization of super-resolution optical microscopy
Q41868144A practical guide to the synthesis of dinitroindolinyl-caged neurotransmitters
Q41518514A silent synapse-based mechanism for cocaine-induced locomotor sensitization
Q48136209Aberrant NMDA-dependent LTD after perinatal ethanol exposure in young adult rat hippocampus.
Q24658061Activation of CaMKII in single dendritic spines during long-term potentiation
Q28508281Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin/neuroligin contacts
Q39210660Afferent Input Selects NMDA Receptor Subtype to Determine the Persistency of Hippocampal LTP in Freely Behaving Mice
Q35626044Altered neuronal excitability underlies impaired hippocampal function in an animal model of psychosis
Q42503084Amphetamine and Methamphetamine Increase NMDAR-GluN2B Synaptic Currents in Midbrain Dopamine Neurons.
Q41423935Anomalous diffusion in Purkinje cell dendrites caused by spines
Q54941342Antioxidant and Cell-Signaling Functions of Hydrogen Sulfide in the Central Nervous System.
Q28075378Basic roles of key molecules connected with NMDAR signaling pathway on regulating learning and memory and synaptic plasticity
Q28575343Brain-derived neurotrophic factor regulation of N-methyl-D-aspartate receptor-mediated synaptic currents in suprachiasmatic nucleus neurons
Q41694511CA1 pyramidal cells have diverse biophysical properties, affected by development, experience, and aging
Q80200135Ca(2+) signaling in dendritic spines
Q41092172CaMKII translocation requires local NMDA receptor-mediated Ca2+ signaling
Q35486043Caged compounds for multichromic optical interrogation of neural systems
Q34392610Caged compounds: photorelease technology for control of cellular chemistry and physiology
Q42566179Calcium signaling in dendritic spines
Q37683462Chemistry and biological applications of photo-labile organic molecules
Q37130682Cocaine Self-Administration Elevates GluN2B within dmPFC Mediating Heightened Cue-Elicited Operant Responding
Q36120602Coexistence of glutamatergic spine synapses and shaft synapses in substantia nigra dopamine neurons
Q61447839Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice
Q30495714Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors
Q41512690Computational investigation of Amyloid-β-induced location- and subunit-specific disturbances of NMDAR at hippocampal dendritic spine in Alzheimer's disease.
Q39142409Control of excitatory synaptic transmission by C-terminal Src kinase
Q48430641Control of neuronal excitability by NMDA-type glutamate receptors in early developing binaural auditory neurons.
Q41788581D1/D5 modulation of synaptic NMDA receptor currents
Q50983767Dendritic spine dynamics regulate the long-term stability of synaptic plasticity.
Q56560851Development of anionically decorated 2-(ortho-nitrophenyl)-propyl-caged neurotransmitters for photolysis in vitro and in vivo
Q64075853Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model
Q37331976Developmental changes in the acute ethanol sensitivity of glutamatergic and GABAergic transmission in the BNST.
Q33315224Developmental presence and disappearance of postsynaptically silent synapses on dendritic spines of rat layer 2/3 pyramidal neurons
Q43182527Differential roles of NMDA Receptor Subtypes NR2A and NR2B in dendritic branch development and requirement of RasGRF1.
Q59075187Differential tuning of excitation and inhibition shapes direction selectivity in ferret visual cortex
Q37060479Dissociable roles for the ventromedial prefrontal cortex and amygdala in fear extinction: NR2B contribution.
Q43091653Distal dendritic inputs control neuronal activity by heterosynaptic potentiation of proximal inputs
Q38956415Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites
Q44750007Distinct and simultaneously active plasticity mechanisms in mouse hippocampus during different phases of Morris water maze training.
Q34070490Distribution of extracellular glutamate in the neuropil of hippocampus
Q39126093Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma
Q34458582Down-regulation of synaptic GluN2B subunit-containing N-methyl-D-aspartate receptors: a physiological brake on CA1 neuron α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hyperexcitability during benzodiazepine withdrawal
Q42125320Dynamic regulation of NMDA receptor transmission
Q48186779Effective release rates at single rat Schaffer collateral-CA1 synapses during sustained theta-burst activity revealed by optical imaging
Q36854707Effects of sex and DTNBP1 (dysbindin) null gene mutation on the developmental GluN2B-GluN2A switch in the mouse cortex and hippocampus
Q90084683Electroacupuncture ameliorates learning and memory deficits via hippocampal 5-HT1A receptors and the PKA signaling pathway in rats with ischemic stroke
Q35137819EphB controls NMDA receptor function and synaptic targeting in a subunit-specific manner
Q36398915Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.
Q38168188Expression mechanisms underlying long-term potentiation: a postsynaptic view, 10 years on
Q53564093Extrasynaptic and synaptic NMDA receptors form stable and uniform pools in rat hippocampal slices.
Q33638949Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release
Q46677393Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS.
Q38168191GluA2-dependent AMPA receptor endocytosis and the decay of early and late long-term potentiation: possible mechanisms for forgetting of short- and long-term memories
Q37350719GluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity.
Q35606178Glutamate spillover promotes the generation of NMDA spikes
Q35585783Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors.
Q48395909Homeostatic metaplasticity of corticospinal excitatory and intracortical inhibitory neural circuits in human motor cortex.
Q83842213In vivo two-photon uncaging of glutamate revealing the structure-function relationships of dendritic spines in the neocortex of adult mice
Q38292612Input transformation by dendritic spines of pyramidal neurons
Q48420995Interaction between αCaMKII and GluN2B controls ERK-dependent plasticity.
Q47892432Intracellular calcium elevation during plateau potentials mediated by extrasynaptic NMDA receptor activation in rat hippocampal CA1 pyramidal neurons is primarily due to calcium entry through voltage-gated calcium channels
Q28509168Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function
Q92297280Kilohertz frame-rate two-photon tomography
Q42287800Locally dynamic synaptic learning rules in pyramidal neuron dendrites
Q26998387Mechanisms of CaMKII action in long-term potentiation
Q35100259Mechanisms of specificity in neuronal activity-regulated gene transcription
Q45935128Metaplastic regulation of long-term potentiation/long-term depression threshold by activity-dependent changes of NR2A/NR2B ratio.
Q42660966Metaplasticity at single glutamatergic synapses
Q64965164Metaplasticity in the Visual Cortex: Crosstalk Between Visual Experience and Reactive Oxygen Species.
Q36754707Modelling intracellular competition for calcium: kinetic and thermodynamic control of different molecular modes of signal decoding
Q38600083Molecular and anatomical evidence for the input pathway- and target cell type-dependent regulation of glutamatergic synapses
Q34974511Molecular determinants controlling NMDA receptor synaptic incorporation
Q46041477Molecular determinants of multiple effects of nickel on NMDA receptor channels
Q48095418Molecular mechanisms of detection and discrimination of dynamic signals
Q48496714N-Methyl d-Aspartate Receptor Expression Patterns in the Human Fetal Cerebral Cortex.
Q36956915NMDA receptor antagonists reveal age-dependent differences in the properties of visual cortical plasticity.
Q34577100NMDA receptor subunits in the adult rat hippocampus undergo similar changes after 5 minutes in an open field and after LTP induction
Q37361657NR2A at CA1 synapses is obligatory for the susceptibility of hippocampal plasticity to sleep loss
Q48914613NR2B-subunit dependent facilitation of long-term potentiation in primary visual cortex following visual discrimination training of adult rats.
Q60937880Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats
Q34553683Nonlinear [Ca2+] signaling in dendrites and spines caused by activity-dependent depression of Ca2+ extrusion.
Q24670490Obligatory role of NR2A for metaplasticity in visual cortex
Q48579924Opposing role of NMDA receptor GluN2B and GluN2D in somatosensory development and maturation.
Q36394413PSD-95 family MAGUKs are essential for anchoring AMPA and NMDA receptor complexes at the postsynaptic density
Q37479508Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines
Q26824647Postsynaptic signaling during plasticity of dendritic spines
Q51052634Presynaptic NMDA receptors act as local high-gain glutamate detector in developing cerebellar molecular layer interneurons.
Q92237868Probing Single Synapses via the Photolytic Release of Neurotransmitters
Q39389361Promoting neurological recovery of function via metaplasticity
Q64290872Properties of Individual Hippocampal Synapses Influencing NMDA-Receptor Activation by Spontaneous Neurotransmission
Q47940043Propofol attenuates BV2 microglia inflammation via NMDA receptor inhibition
Q46987195Protein kinase A regulates calcium permeability of NMDA receptors.
Q38820173Pushing the threshold: How NMDAR antagonists induce homeostasis through protein synthesis to remedy depression.
Q37877208Quantification of postsynaptic density proteins: glutamate receptor subunits and scaffolding proteins
Q36408158REST-dependent epigenetic remodeling promotes the developmental switch in synaptic NMDA receptors.
Q33566849Rapid functional maturation of nascent dendritic spines
Q37086625Rapid, bidirectional remodeling of synaptic NMDA receptor subunit composition by A-type K+ channel activity in hippocampal CA1 pyramidal neurons
Q36408077Regulation of NMDA receptor Ca2+ signalling and synaptic plasticity
Q36990383Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity
Q37878425Regulation of long-term plasticity induction by the channel and C-terminal domains of GluN2 subunits
Q37039291Regulation of synaptic signalling by postsynaptic, non-glutamate receptor ion channels.
Q46793959Roles of NR2A and NR2B in the development of dendritic arbor morphology in vivo.
Q33464333RuBi-Glutamate: Two-Photon and Visible-Light Photoactivation of Neurons and Dendritic spines
Q28395155Segregation and crosstalk of D1 receptor-mediated activation of ERK in striatal medium spiny neurons upon acute administration of psychostimulants
Q39689536Single- and two-photon fluorescence recovery after photobleaching.
Q42926396Single-molecule patch-clamp FRET microscopy studies of NMDA receptor ion channel dynamics in living cells: revealing the multiple conformational states associated with a channel at its electrical off state
Q37252656Size and Receptor Density of Glutamatergic Synapses: A Viewpoint from Left-Right Asymmetry of CA3-CA1 Connections.
Q37750483Spatiotemporal Regulation of Signaling in and out of Dendritic Spines: CaMKII and Ras.
Q34901087Spine neck plasticity controls postsynaptic calcium signals through electrical compartmentalization.
Q34147787Spine pruning in 5xFAD mice starts on basal dendrites of layer 5 pyramidal neurons
Q28581895Subcellular dynamics of type II PKA in neurons
Q36376173Subcellular synaptic connectivity of layer 2 pyramidal neurons in the medial prefrontal cortex
Q46021064Substrate localization creates specificity in calcium/calmodulin-dependent protein kinase II signaling at synapses.
Q28581987Surface dynamics of GluN2B-NMDA receptors controls plasticity of maturing glutamate synapses
Q36568016Synapse-specific and size-dependent mechanisms of spine structural plasticity accompanying synaptic weakening
Q41467150Synapse-specific metaplasticity: to be silenced is not to silence 2B.
Q38252776Synaptic Plasticity and Memory: New Insights from Hippocampal Left-Right Asymmetries
Q38053382The BCM theory of synapse modification at 30: interaction of theory with experiment
Q36698148The blockade of NMDA receptor ion channels by ketamine is enhanced in developing rat cortical neurons
Q42852137The dynamics of excitatory synapse formation on dendritic spines
Q28473837The effects of NR2 subunit-dependent NMDA receptor kinetics on synaptic transmission and CaMKII activation
Q37856526The mechanisms underlying the spatial spreading of signaling activity
Q38222677The neural rejuvenation hypothesis of cocaine addiction
Q43247737The role of NMDA receptor subtypes in short-term plasticity in the rat entorhinal cortex
Q37951747The role of glutamate in neuronal ischemic injury: the role of spark in fire
Q52371529The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions.
Q46793924Three-dimensional mapping of unitary synaptic connections by two-photon macro photolysis of caged glutamate.
Q33932141Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.
Q30525038Translocation of CaMKII to dendritic microtubules supports the plasticity of local synapses
Q61450039Two-Photon Uncaging of Glutamate
Q35075460Two-photon microscopy for chemical neuroscience
Q41903642Two-photon uncaging of gamma-aminobutyric acid in intact brain tissue
Q29616778Ultrasensitive fluorescent proteins for imaging neuronal activity
Q35547363Variations in the stimulus salience of cocaine reward influences drug-associated contextual memory

Search more.