| scholarly article | Q13442814 |
| P2093 | author name string | J. V. Bonventre | |
| J. M. Kyriakis | |||
| T. Force | |||
| G. Choukroun | |||
| R. Hajjar | |||
| A. Rosenzweig | |||
| P2860 | cites work | Protein measurement with the Folin phenol reagent | Q20900776 |
| Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase | Q24303413 | ||
| JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 | ||
| Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway | Q24315773 | ||
| Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex | Q24316473 | ||
| Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases | Q24316962 | ||
| Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA | Q27748936 | ||
| Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation | Q28131755 | ||
| A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells | Q28237789 | ||
| Endothelin ETA receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload | Q72415175 | ||
| The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion | Q72724668 | ||
| Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophy | Q72863732 | ||
| Is there major involvement of the renin-angiotensin system in cardiac hypertrophy? | Q73833043 | ||
| GATA4: a novel transcriptional regulator of cardiac hypertrophy? | Q73951488 | ||
| Chronic endothelin receptor blockade attenuates progressive ventricular dilation and improves cardiac function in rats with myocardial infarction: possible involvement of myocardial endothelin system in ventricular remodeling | Q73951519 | ||
| Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy | Q74469678 | ||
| T lymphocyte activation signals for interleukin-2 production involve activation of MKK6-p38 and MKK7-SAPK/JNK signaling pathways sensitive to cyclosporin A | Q74516852 | ||
| Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells | Q28263599 | ||
| A calcineurin-dependent transcriptional pathway for cardiac hypertrophy | Q28269300 | ||
| The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression | Q28504813 | ||
| Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro | Q28570955 | ||
| MAP kinase- and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells | Q28580197 | ||
| A cytoplasmic inhibitor of the JNK signal transduction pathway | Q28586970 | ||
| Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts | Q28609143 | ||
| The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
| Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun | Q29620103 | ||
| The regulation of AP-1 activity by mitogen-activated protein kinases | Q29620431 | ||
| Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors | Q30452676 | ||
| Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy | Q33774336 | ||
| Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes | Q34243039 | ||
| A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression | Q34440843 | ||
| Inhibition of a signaling pathway in cardiac muscle cells by active mitogen-activated protein kinase kinase | Q34452835 | ||
| Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family | Q34453631 | ||
| Phosphorylation of c-jun mediated by MAP kinases. | Q34947174 | ||
| GTPase-deficient G alpha 16 and G alpha q induce PC12 cell differentiation and persistent activation of cJun NH2-terminal kinases | Q36557162 | ||
| The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium | Q36561845 | ||
| The search for physiological substrates of MAP and SAP kinases in mammalian cells | Q36914508 | ||
| Adenovirus infection stimulates the Raf/MAPK signaling pathway and induces interleukin-8 expression | Q39877707 | ||
| Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism | Q40872674 | ||
| Control of cardiac gene expression by mechanical stress | Q40893603 | ||
| Stress-activated protein kinases in cardiovascular disease | Q40989426 | ||
| Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion | Q41074846 | ||
| Sounding the alarm: protein kinase cascades activated by stress and inflammation | Q41106742 | ||
| Mek1 phosphorylation site mutants activate Raf-1 in NIH 3T3 cells | Q41145783 | ||
| The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat | Q41200518 | ||
| Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. | Q41218044 | ||
| JNK is involved in signal integration during costimulation of T lymphocytes. | Q41461688 | ||
| Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy | Q41845484 | ||
| Induction of mitogen-activated protein kinase phosphatase 1 by the stress-activated protein kinase signaling pathway but not by extracellular signal-regulated kinase in fibroblasts | Q42817534 | ||
| Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy | Q44207696 | ||
| Physiological effects of adenoviral gene transfer of sarcoplasmic reticulum calcium ATPase in isolated rat myocytes | Q45880430 | ||
| HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. | Q45945033 | ||
| Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice. | Q46009276 | ||
| The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy. | Q46028223 | ||
| Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes | Q46055914 | ||
| Transcriptional squelching re-examined | Q58985650 | ||
| Inhibition of myocardial endothelin pathway improves long-term survival in heart failure | Q59063327 | ||
| Negative effect of the transcriptional activator GAL4 | Q59072863 | ||
| Cellular Stresses Differentially Activate c-Jun N-terminal Protein Kinases and Extracellular Signal-regulated Protein Kinases in Cultured Ventricular Myocytes | Q63208064 | ||
| Mechanical stretch activates the stress-activated protein kinases in cardiac myocytes | Q71057752 | ||
| Angiotensin II stimulates c-Jun NH2-terminal kinase in cultured cardiac myocytes of neonatal rats | Q71933803 | ||
| Endothelin-1 and its binding sites are upregulated in pressure overload cardiac hypertrophy | Q72289356 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1311–1320 | |
| P577 | publication date | 1998-10-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy | |
| P478 | volume | 102 |
| Q38173671 | A pathway and network review on beta-adrenoceptor signaling and beta blockers in cardiac remodeling |
| Q33883079 | Activation of protein kinase cascades in the heart by hypertrophic G protein-coupled receptor agonists |
| Q44075487 | Aldosterone augments endothelin-1-induced cardiac myocyte hypertrophy with the reinforcement of the JNK pathway |
| Q79808415 | An autocrine role for leptin in mediating the cardiomyocyte hypertrophic effects of angiotensin II and endothelin-1 |
| Q94551088 | Antihypertensive activity of a new c-Jun N-terminal kinase inhibitor in spontaneously hypertensive rats |
| Q40816391 | Calcineurin enhances MAPK phosphatase-1 expression and p38 MAPK inactivation in cardiac myocytes. |
| Q77369735 | Calcineurin inhibitors and cardiac hypertrophy |
| Q33665828 | Cardiac hypertrophy: sorting out the circuitry |
| Q33852546 | Cardiac signal transduction |
| Q36544841 | Characterization of hsp27 kinases activated by elevated aortic pressure in heart. |
| Q43002766 | Chronic activation of extracellular-signal-regulated protein kinases by phenylephrine is required to elicit a hypertrophic response in cardiac myocytes |
| Q28237359 | Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA |
| Q44391284 | Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for ar |
| Q34289211 | Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: therapeutic perspectives |
| Q35127402 | Cytosolic phospholipase A(2) regulates golgi structure and modulates intracellular trafficking of membrane proteins |
| Q36570938 | Cytosolic phospholipase A2α regulates G1 progression through modulating FOXO1 activity |
| Q58198513 | Distinct gene expression profiles in adult mouse heart following targeted MAP kinase activation |
| Q28583675 | Distinct roles of mitogen-activated protein kinase pathways in GATA-4 transcription factor-mediated regulation of B-type natriuretic peptide gene |
| Q36421781 | Electrical and mechanical stimulation of cardiac cells and tissue constructs. |
| Q35056026 | Emerging therapeutic targets in chronic heart failure: part II. |
| Q42560002 | Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation |
| Q35109612 | Garlic Oil Alleviates MAPKs- and IL-6-mediated Diabetes-related Cardiac Hypertrophy in STZ-induced DM Rats |
| Q22253460 | Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stre |
| Q41491151 | Gene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling. |
| Q36358042 | Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy |
| Q40424953 | HSP72 can protect cells from heat-induced apoptosis by accelerating the inactivation of stress kinase JNK. |
| Q24673841 | Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction |
| Q34279049 | Hsp72 and stress kinase c-jun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis |
| Q24290139 | Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death |
| Q24303697 | Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways |
| Q39129176 | Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype |
| Q33827585 | Impulse conduction and gap junctional remodelling by endothelin-1 in cultured neonatal rat ventricular myocytes. |
| Q46720904 | Inhibitory effect of trilinolein on endothelin-1-induced c-fos gene expression in cultured neonatal rat cardiomyocytes |
| Q46438380 | Integrin stimulation-induced hypertrophy in neonatal rat cardiomyocytes is NO-dependent |
| Q91593479 | JNK and cardiometabolic dysfunction |
| Q35783613 | JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure |
| Q24302601 | Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy. |
| Q81044990 | Lipopolysaccharide induces cellular hypertrophy through calcineurin/NFAT-3 signaling pathway in H9c2 myocardiac cells |
| Q33902374 | Mechanical strain activates BNP gene transcription through a p38/NF-kappaB-dependent mechanism |
| Q51438500 | MicroRNA-200c modulates DUSP-1 expression in diabetes-induced cardiac hypertrophy. |
| Q52033655 | Mitogen-activated protein kinase activation and regulation in the pressure-loaded fetal ovine heart. |
| Q28296128 | Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale |
| Q35169365 | Mitogen-activated protein kinases: a new therapeutic target in cardiac pathology |
| Q39635390 | Mitogen‐activated protein kinase in endothelin‐1‐induced cardiac differentiation of mouse embryonic stem cells |
| Q58604151 | Mixed Lineage Kinase 3 (MLK3) Prevents Cardiac Dysfunction and Structural Remodeling with Pressure Overload |
| Q73401434 | Myosin light chain kinase mediates sarcomere organization during cardiac hypertrophy in vitro |
| Q24614013 | Myostatin regulates cardiomyocyte growth through modulation of Akt signaling |
| Q43823964 | Osmoregulation of natriuretic peptide receptor signaling in inner medullary collecting duct. A requirement for p38 MAPK. |
| Q54023507 | Overexpression of mitogen-activated protein kinase superfamily proteins unrelated to Ras and AF-1 of estrogen receptor alpha mutation in advanced stage human breast cancer. |
| Q44771526 | PKC-epsilon regulation of extracellular signal-regulated kinase: a potential role in phenylephrine-induced cardiocyte growth |
| Q57174535 | PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart |
| Q53763863 | Phosphatidylinositol 3'-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products. |
| Q40648961 | Protection of Renal Epithelial Cells against Oxidative Injury by Endoplasmic Reticulum Stress Preconditioning Is Mediated by ERK1/2 Activation |
| Q33857393 | Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH(2)-terminal kinases |
| Q39235339 | Regulation of cardiac melusin gene expression by hypertrophic stimuli in the rat. |
| Q34389386 | Role of endothelin in the induction of cardiac hypertrophy in vitro |
| Q36567326 | Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndrome |
| Q46653313 | Role of oxidative stress in hypertrophied myoblasts stimulated by isoproterenol |
| Q38509313 | Samul extract protects against the H2O2-induced apoptosis of H9c2 cardiomyoblasts via activation of extracellular regulated kinases (Erk) 1/2. |
| Q24548383 | Serum response factor-GATA ternary complex required for nuclear signaling by a G-protein-coupled receptor |
| Q38362119 | Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy |
| Q33706919 | Signaling pathways mediating the response to hypertrophic stress in the heart. |
| Q28344062 | Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro |
| Q28204228 | Stimulation of endothelin B receptors in astrocytes induces cAMP response element-binding protein phosphorylation and c-fos expression via multiple mitogen-activated protein kinase signaling pathways |
| Q46875217 | Subdepressor dose of benidipine ameliorates diabetic cardiac remodeling accompanied by normalization of upregulated endothelin system in rats |
| Q50735846 | Systematic Evaluation of Endothelin 1 Measurement Relative to Traditional and Modern Biomarkers for Clinical Assessment and Prognosis in Patients With Chronic Systolic Heart Failure: Serial Measurement and Multimarker Testing. |
| Q46858649 | Targeted activation of c-Jun N-terminal kinase in vivo induces restrictive cardiomyopathy and conduction defects |
| Q28343890 | Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy |
| Q39752687 | Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling |
| Q40388321 | The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice |
| Q34793636 | The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy. |
| Q61912834 | The Multiple Actions of the Insulin-Like Growth Factor-I Signaling in the Myocardium |
| Q34992234 | The effect of adrenalectomy on the cardiac response to subacute fetal anemia. |
| Q36067020 | The role of endothelin-1 in myocarditis and inflammatory cardiomyopathy: old lessons and new insights. |
| Q36610320 | The role of the paracrine/autocrine mediator endothelin-1 in regulation of cardiac contractility and growth. |
| Q24548283 | The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes |
| Q42504443 | The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo. |
| Q45046483 | Transgenic mice with cardiac-specific over-expression of MLK7 have increased mortality when exposed to chronic beta-adrenergic stimulation |
| Q43960692 | Up-regulation of thrombospondin-1 gene by epidermal growth factor and transforming growth factor beta in human cancer cells--transcriptional activation and messenger RNA stabilization |
| Q37101602 | With great power comes great responsibility: using mouse genetics to study cardiac hypertrophy and failure |
| Q41736665 | alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response |
| Q28346420 | c-Jun N-terminal kinase-interacting protein 1 inhibits gene expression in response to hypertrophic agonists in neonatal rat ventricular myocytes |
| Q39927730 | c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling |
| Q46514933 | p38 MAP-kinase in cultured adult rat ventricular cardiomyocytes: expression and involvement in hypertrophic signalling |
| Q34372422 | p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. |
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