alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response

scientific article published on August 2000

alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M003864200
P698PubMed publication ID10816593

P2093author name stringGlembotski CC
Martindale JJ
Thuerauf DJ
Hoover HE
P2860cites workInvolvement of multiple cis elements in basal- and alpha-adrenergic agonist-inducible atrial natriuretic factor transcription. Roles for serum response elements and an SP-1-like elementQ38288684
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p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model systemQ41732350
Stimulation of multiple mitogen-activated protein kinase sub-families by oxidative stress and phosphorylation of the small heat shock protein, HSP25/27, in neonatal ventricular myocytesQ41954007
Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy?Q42797088
MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent mannerQ44160668
p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6.Q46291076
Mitogen-activated protein kinase cascades as regulators of stress responsesQ46899777
Small heat shock proteins and protection against ischemic injury in cardiac myocytesQ46972878
Temporospatial expression of the small HSP/alpha B-crystallin in cardiac and skeletal muscle during mouse developmentQ47628295
Dispensability of the actin-binding site and spectrin repeats for targeting sarcomeric alpha-actinin into maturing Z bands in vivo: implications for in vitro binding studiesQ47709623
Dementia, gliosis and expression of the small heat shock proteins hsp27 and alpha B-crystallin in Parkinson's diseaseQ48142025
Tissue-specific expression of the human brain natriuretic peptide gene in cardiac myocytesQ49104362
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cellsQ50336697
Phosphorylation of alphaB-crystallin in mitotic cells and identification of enzymatic activities responsible for phosphorylation.Q52183272
Phosphorylation of alphaB-crystallin in response to various types of stress.Q52191790
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathyQ24311671
Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinasesQ24316962
PRAK, a novel protein kinase regulated by the p38 MAP kinaseQ24336112
Expression of the murine alpha B-crystallin gene is not restricted to the lensQ24633848
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathwayQ24650627
A simplified system for generating recombinant adenovirusesQ24682328
SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosisQ24682451
Nebulette: a 107 kD nebulin-like protein in cardiac muscleQ28274545
Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophyQ28565539
alpha B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissuesQ28568273
Abundance and location of the small heat shock proteins HSP25 and alphaB-crystallin in rat and human heartQ28573782
Stress pathways and heart failureQ33734297
Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophyQ33774336
The p38 signal transduction pathway: activation and functionQ33838955
Future perspectives and potential implications of cardiac myocyte apoptosisQ33870066
Nspl1, a new Z-band-associated proteinQ33889821
A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expressionQ34440843
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase familyQ34453631
Alpha B-crystallin in cardiac tissue. Association with actin and desmin filamentsQ34466918
Regulation of the murine alpha B-crystallin/small heat shock protein gene in cardiac muscleQ36556539
The search for physiological substrates of MAP and SAP kinases in mammalian cellsQ36914508
Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like functionQ37198800
P433issue31
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
cardiac stressQ21119047
P1104number of pages9
P304page(s)23825-23833
P577publication date2000-08-01
P1433published inJournal of Biological ChemistryQ867727
P1476titlealpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response
P478volume275

Reverse relations

cites work (P2860)
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