Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion

scientific article published on 9 November 2007

Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.00881.2007
P698PubMed publication ID17993600

P2093author name stringC C Glembotski
S B Barlow
R Whittaker
R A Gottlieb
J-K Jin
M S Glassy
P2860cites workHuman alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosisQ24306784
Expression of the murine alpha B-crystallin gene is not restricted to the lensQ24633848
p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophilsQ28141837
Inhibition of proteasomes induces accumulation, phosphorylation, and recruitment of HSP27 and alphaB-crystallin to aggresomesQ28211937
alpha B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissuesQ28568273
Ischemia-induced association of the stress protein alpha B-crystallin with I-band portion of cardiac titinQ28583343
Transgene overexpression of alphaB crystallin confers simultaneous protection against cardiomyocyte apoptosis and necrosis during myocardial ischemia and reperfusionQ31825986
Alpha B-crystallin in cardiac tissue. Association with actin and desmin filamentsQ34466918
Alpha B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brainQ35416428
Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotectionQ35666876
Protein kinase activation and myocardial ischemia/reperfusion injuryQ35666889
Small heat shock proteins: a new classification scheme in mammalsQ36055893
Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivoQ36952671
Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosisQ40183315
Association of alphaB-crystallin, a small heat shock protein, with actin: role in modulating actin filament dynamics in vivoQ40188464
MAPK-activated protein kinase-2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27.Q40224907
The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.Q40470289
The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activationQ40715426
Mimicking phosphorylation of alphaB-crystallin affects its chaperone activityQ41084011
alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress responseQ41736665
The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturationQ43556597
Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosisQ44306740
Roles for αB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse modelQ44639137
Association of the chaperone alphaB-crystallin with titin in heart muscle.Q44693938
Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?Q52123671
Phosphorylation of alphaB-crystallin in response to various types of stress.Q52191790
CRYAB and HSPB2 deficiency increases myocyte mitochondrial permeability transition and mitochondrial calcium uptake.Q53624149
P433issue1
P921main subjectmitochondrionQ39572
phosphorylationQ242736
P304page(s)H337-44
P577publication date2007-11-09
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titleLocalization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion
P478volume294

Reverse relations

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