scholarly article | Q13442814 |
P356 | DOI | 10.1093/TOXSCI/KFH016 |
P953 | full work available at URL | http://toxsci.oxfordjournals.org/content/77/1/19.full.pdf |
http://academic.oup.com/toxsci/article-pdf/77/1/19/16691419/z1200104000019.pdf | ||
P698 | PubMed publication ID | 14600272 |
P2093 | author name string | Heidrun Ellinger-Ziegelbauer | |
Barry Stuart | |||
Brad Wahle | |||
Hans-Jurgen Ahr | |||
Werner Bomann | |||
P2860 | cites work | Initial sequencing and analysis of the human genome | Q21045365 |
The Sequence of the Human Genome | Q22065842 | ||
Initial sequencing and comparative analysis of the mouse genome | Q22122521 | ||
Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes | Q24308695 | ||
Thymosin beta-10 gene overexpression is a general event in human carcinogenesis | Q24670864 | ||
Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor | Q24683260 | ||
Surfing the p53 network | Q28032484 | ||
The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
Retinoic acid repressed the expression of c-fos and c-jun and induced apoptosis in regenerating rat liver after partial hepatectomy | Q28564781 | ||
Anti-inflammatory agents and inducibility of hepatic drug metabolism | Q28570043 | ||
Microarray analysis of differential gene expression in lead-exposed astrocytes | Q28571265 | ||
p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents | Q28579401 | ||
Annexins: from structure to function | Q29616171 | ||
Transcriptional control of hepatocanalicular transporter gene expression | Q34081626 | ||
Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention | Q34100023 | ||
Challenges and limitations of gene expression profiling in mechanistic and predictive toxicology | Q34164559 | ||
New models for assessing carcinogenesis: an ongoing process | Q34232376 | ||
Physiological function as regulation of large transcriptional programs: the cellular response to genotoxic stress | Q34297822 | ||
Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53 | Q34388427 | ||
Toxicogenomics; transcript profiling and potential application to chemical allergy | Q34646399 | ||
Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes | Q34946568 | ||
Recent studies on metallothionein: protection against toxicity of heavy metals and oxygen free radicals | Q35033016 | ||
Sense and antisense modification of glial alpha B-crystallin production results in alterations of stress fiber formation and thermoresistance | Q36534876 | ||
Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients | Q36621223 | ||
Intracellular pH and the control of multidrug resistance | Q37558951 | ||
Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches | Q38296572 | ||
Transcriptional activation of the small GTPase gene rhoB by genotoxic stress is regulated via a CCAAT element | Q38304655 | ||
Prediction of compound signature using high density gene expression profiling | Q38456725 | ||
Early formation of DNA adducts compared with tumor formation in a long-term tumor study in rats after administration of 2-nitrofluorene | Q39371681 | ||
Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate | Q40674915 | ||
DNA microarrays identification of primary and secondary target genes regulated by p53. | Q40799703 | ||
Transforming growth factor beta induces caspase 3-independent cleavage of alphaII-spectrin (alpha-fodrin) coincident with apoptosis | Q40937155 | ||
Multidrug resistance proteins and other drug transport-related resistance to natural product agents. | Q40938356 | ||
alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response | Q41736665 | ||
A role for ID repetitive sequences in growth- and transformation-dependent regulation of gene expression in rat fibroblasts | Q43634475 | ||
IFN-gamma-inducible protein-10 (CXCL10) is hepatoprotective during acute liver injury through the induction of CXCR2 on hepatocytes | Q43819919 | ||
Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis | Q43858122 | ||
Evidence for phosphate adducts in DNA from mice treated with 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK). | Q44029798 | ||
Gene expression profile induced by 17alpha-ethynyl estradiol, bisphenol A, and genistein in the developing female reproductive system of the rat. | Q44035456 | ||
Modulation of gene and protein expression by carbon tetrachloride in the rat liver | Q44129138 | ||
Gene modulation in total brain induced by exposure to the bicyclic phosphorus ester trimethylolpropane phosphate (TMPP). | Q44133041 | ||
Identifying toxic mechanisms using DNA microarrays: evidence that an experimental inhibitor of cell adhesion molecule expression signals through the aryl hydrocarbon nuclear receptor | Q44264860 | ||
Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways | Q44270136 | ||
Gene expression profile induced by 17 alpha-ethynyl estradiol in the prepubertal female reproductive system of the rat. | Q44374592 | ||
Bioactivation of 2-nitrofluorene to reactive intermediates that bind covalenty to DNA, RNA and protein in vitro and in vivo in the rat | Q44950492 | ||
GGF/neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors | Q48956089 | ||
Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice. | Q52199698 | ||
Activation of distinct multidrug-resistance (P-glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis. | Q53484824 | ||
Aflatoxin B1 binding to plasma albumin and liver DNA upon chronic administration to rats. | Q53536653 | ||
Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents. | Q53554718 | ||
The ineffectiveness of reduced glutathione in preventing the development of liver tumours from aflatoxin-induced pre-neoplastic liver lesions. | Q53775447 | ||
Comparison of early injury to liver endoplasmic reticulum by halomethanes, hexachloroethane, benzene, toluene, bromobenzene, ethionine, thioacetamide and dimethylnitrosamine. | Q53813652 | ||
Prevention of growth arrest-induced cell death of vascular smooth muscle cells by a product of growth arrest-specific gene, gas6 | Q71130353 | ||
NCAM, vimentin and neonatal myosin heavy chain expression in human muscle diseases | Q73189546 | ||
Gene expression analysis reveals chemical-specific profiles | Q74100166 | ||
Toxicogenomics and drug discovery: will new technologies help us produce better drugs? | Q74466201 | ||
The International Life Sciences Institute's role in the evaluation of alternative methodologies for the assessment of carcinogenic risk | Q77140335 | ||
Identification of toxicologically predictive gene sets using cDNA microarrays | Q77292517 | ||
Recent advances on cyclins, CDKs and CDK inhibitors | Q80818113 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | toxicogenomics | Q841450 |
genotoxicity | Q1009245 | ||
gene expression profiling | Q1502169 | ||
P304 | page(s) | 19-34 | |
P577 | publication date | 2003-11-04 | |
P1433 | published in | Toxicological Sciences | Q2446966 |
P1476 | title | Characteristic expression profiles induced by genotoxic carcinogens in rat liver | |
Characteristic Expression Profiles Induced by Genotoxic Carcinogens in Rat Liver | |||
P478 | volume | 77 |
Q85183513 | A preliminary report on the toxicity of arecoline on early pregnancy in mice |
Q36892476 | A retrospective analysis of toxicogenomics in the safety assessment of drug candidates. |
Q39580169 | Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation |
Q23918078 | Application of oligonucleotide microarray technology to toxic occupational exposures |
Q40042046 | Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: an in silico comparison with mutagenic and nonmutagenic carcinogens across tissues |
Q28396010 | Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans |
Q64251527 | Biological System Responses of Dairy Cows to Aflatoxin B1 Exposure Revealed with Metabolomic Changes in Multiple Biofluids |
Q53316445 | Biomarkers of carcinogenicity and their roles in drug discovery and development. |
Q36009614 | Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma. |
Q30572803 | Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data |
Q40415408 | Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling |
Q28075960 | Critical role of toxicologic pathology in a short-term screen for carcinogenicity |
Q42728391 | Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat. |
Q48605988 | Differential display in rat livers treated for 13 weeks with phenobarbital implicates a role for metabolic and oxidative stress in nongenotoxic carcinogenicity |
Q33255753 | Discovering antibiotic efficacy biomarkers: toward mechanism-specific high content compound screening |
Q47205550 | Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling |
Q45423052 | Distinguishing between genotoxic and non-genotoxic hepatocarcinogens by gene expression profiling and bioinformatic pathway analysis |
Q58802798 | Effect of autophagy-associated proteins on the arecoline-induced liver injury in mice |
Q33580465 | Effects of lipoic acid on immune function, the antioxidant defense system, and inflammation-related genes expression of broiler chickens fed aflatoxin contaminated diets |
Q46095177 | Engineering of Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor. |
Q58774687 | Estradiol Prevents High Glucose-Induced β-cell Apoptosis by Decreased BTG2 Expression |
Q28025433 | Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes |
Q58109635 | Evaluation of Aflatoxin M1 Effects on the Metabolomic and Cytokinomic Profiling of a Hepatoblastoma Cell Line |
Q85026459 | GADD45α induction in the greenscreen HC indicator assay does not occur independently of cytotoxicity |
Q46970658 | Gene expression dose-response of liver with a genotoxic and nongenotoxic carcinogen |
Q36572578 | Gene expression profiling for pharmaceutical safety assessment |
Q50071404 | Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment |
Q47558825 | HAfTs are novel lncRNA transcripts from aflatoxin exposure |
Q42733623 | Identification of biomarkers of chemically induced hepatocarcinogenesis in rasH2 mice by toxicogenomic analysis |
Q43550464 | Identification of specific mRNA signatures as fingerprints for carcinogenesis in mice induced by genotoxic and nongenotoxic hepatocarcinogens |
Q36980449 | Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection. |
Q38514958 | Literature-based compound profiling: application to toxicogenomics |
Q47445329 | Metabolomic analysis of alterations in lipid oxidation, carbohydrate and amino acid metabolism in dairy goats caused by exposure to Aflotoxin B1. |
Q35946295 | Molecular biomarkers in drug development |
Q37121662 | Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. |
Q33628796 | Stem cell proliferation patterns as an alternative for in vivo prediction and discrimination of carcinogenic compounds. |
Q51636797 | Systems Responses of Rats to Aflatoxin B1 Exposure Revealed with Metabonomic Changes in Multiple Biological Matrices |
Q23918082 | The effect of oxythioquinox exposure on normal human mammary epithelial cell gene expression: a microarray analysis study |
Q50769278 | Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats. |
Q35633882 | Toxicogenomic biomarkers for liver toxicity |
Q35968452 | Toxicogenomics and systems toxicology: aims and prospects |
Q36052609 | Toxicogenomics: regulatory perspective on current position |
Q39701197 | Toxicological evaluation of z24, a novel indolin-2-ketone compound, in cultured human liver cells using toxicogenomic techniques |
Q37718523 | Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury. |
Q39197586 | Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models |
Q81019750 | VeloceGenomics: an accelerated in vivo drug discovery approach to rapidly predict the biologic, drug-like activity of compounds, proteins, or genes |
Q48893021 | WITHDRAWN: Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: an alternative approach |
Search more.