Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy?

scientific article published on July 1998

Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1083/JCB.142.2.523
P932PMC publication ID2133061
P698PubMed publication ID9679149
P5875ResearchGate publication ID13606245

P2093author name stringA Michael
A Clerk
P H Sugden
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p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2Q28646211
Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38deltaQ28646538
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Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophyQ41845484
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Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated responseQ44237547
Coupling of the type A endothelin receptor to multiple responses in adult rat cardiac myocytes.Q45969731
The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy.Q46028223
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Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein gQ46155378
Does protein kinase C play a role in ischemic preconditioning in rat hearts?Q46669125
The primary structure of p38 gamma: a new member of p38 group of MAP kinasesQ46763189
Endothelin-1-dependent signaling pathways in the myocardiumQ47772935
Cellular Stresses Differentially Activate c-Jun N-terminal Protein Kinases and Extracellular Signal-regulated Protein Kinases in Cultured Ventricular MyocytesQ63208064
Hypertrophic Agonists Stimulate the Activities of the Protein Kinases c-Raf and A-Raf in Cultured Ventricular MyocytesQ63208072
The Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular CardiomyocytesQ63208084
Expression of protein kinase C isoforms during cardiac ventricular developmentQ63208105
Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophyQ63208155
Endothelin-1, phorbol esters and phenylephrine stimulate MAP kinase activities in ventricular cardiomyocytesQ63208226
Alpha 1-adrenergic stimulation of cardiac gene transcription in neonatal rat myocardial cells. Effects on myosin light chain-2 gene expressionQ69826112
Stimulation of hypertrophy of cultured neonatal rat heart cells through an alpha 1-adrenergic receptor and induction of beating through an alpha 1- and beta 1-adrenergic receptor interaction. Evidence for independent regulation of growth and beatingQ70089448
Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytesQ70198102
Preconditioning against myocardial dysfunction after ischemia and reperfusion by an alpha 1-adrenergic mechanismQ70474449
Thrombin induces activation of p38 MAP kinase in human plateletsQ71585578
Activation of multiple mitogen-activated protein kinase signal transduction pathways by the endothelin B receptor requires the cytoplasmic tailQ71825737
Preconditioning of isolated rat heart is mediated by protein kinase CQ71988463
Protein kinase C. Its role in ischemic preconditioning in the ratQ72133144
Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophyQ72863732
Pretreatment with endothelin-1 mimics ischemic preconditioning against infarction in isolated rabbit heartQ73020232
Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cellsQ73106953
Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidneyQ73555562
Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heartQ73702803
Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stressesQ74358725
The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinases/c-Jun N-terminal kinases (SAPKs/JNKs)Q74582929
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P304page(s)523-535
P577publication date1998-07-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleStimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy?
P478volume142

Reverse relations

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